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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/2.12/bioc/html/rGADEM.html
R package with tools for de novo motif discovery in large-scale genomic sequence data.
Proper citation: rGADEM (RRID:SCR_001091) Copy
http://sourceforge.net/projects/qips/
A software package for analyzing ChIP-seq (Chromatin ImmunoPrecipitation on sequencing) data that finds enriched regions of arbitrary lengths and is therefore especially suited for analyzing ChIP-seq of histone marks or polymerase.
Proper citation: qips (RRID:SCR_001092) Copy
An application designed for compression of data files containing reads from DNA sequencing in FASTQ format. Its main features include multithreaded compression of FASTQ output, python and C++ libraries, and support for lossy IDs compression.
Proper citation: DSRC (RRID:SCR_001005) Copy
A high-performance visualization tool for interactive exploration of large, integrated genomic datasets written primarily in JavaScript. It supports a wide variety of data types, including array-based and next-generation sequence data, and genomic annotations.
Proper citation: JBrowse (RRID:SCR_001004) Copy
http://www.nature.com/subject/nextgenseq
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2025. A collection of latest articles published by Nature Publishing Group about the current state of next generation sequencing technologies.
Proper citation: NextGenSeq(at)nature.com (RRID:SCR_001083) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowWorkspace.html
Software package that facilitates comparison of automated gating methods against manual gating done in flowJo. This package allows you to import basic flowJo workspaces into BioConductor and replicate the gating from flowJo using the flowCore functionality. Gating hierarchies, groups of samples, compensation, and transformation are performed so that the output matches the flowJo analysis.
Proper citation: flowWorkspace (RRID:SCR_001155) Copy
http://131.174.198.125/bioinfo/gimmemotifs/
Software that provides a de novo motif prediction pipeline, especially suited for ChIP-seq datasets. It incorporates several existing motif prediction algorithms in an ensemble method to predict motifs and clusters these motifs using the WIC similarity scoring metric., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: GimmeMotifs (RRID:SCR_001146) Copy
http://dna.leeds.ac.uk/illuminator/
A sequence alignment program for the output from Illumina GA-II clonal sequencers. It uses an algorithm that indexes the reference sequence as a series of 8-mers and then matches the genomic reads to the 8-mer index, in a mutation-tolerant way permitting identification of single-nucleotide substitutions and indels.
Proper citation: Illuminator (RRID:SCR_001019) Copy
http://www.bioconductor.org/packages/release/bioc/html/ArrayExpress.html
Software to access the ArrayExpress Repository at EBI and build Bioconductor data structures: ExpressionSet, AffyBatch, NChannelSet
Proper citation: ArrayExpress (R) (RRID:SCR_000120) Copy
http://sourceforge.net/projects/dtailor/
A fully extendable software framework, for property-based design of synthetic DNA sequences.
Proper citation: D-Tailor (RRID:SCR_000115) Copy
http://www.bioconductor.org/packages/release/bioc/html/AffyRNADegradation.html
Software package that helps with the assessment and correction of RNA degradation effects in Affymetrix 3' expression arrays. The parameter d gives a robust and accurate measure of RNA integrity. The correction removes the probe positional bias, and thus improves comparability of samples that are affected by RNA degradation.
Proper citation: AffyRNADegradation (RRID:SCR_000118) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 18,2023. A free bioinformatics software tool to help identify fusion transcripts from paired-end transcriptome sequencing data. The source codes of SnowShoes-FTD are provided in two formats: one configured to run on the Sun Grid Engine for parallelization with shorter run time, and the other formatted to run on a single LINUX node.
Proper citation: SnowsShoes-FTD (RRID:SCR_000076) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/VariantAnnotation.html
Software package to annotate variants, compute amino acid coding changes, and predict coding outcomes.
Proper citation: VariantAnnotation (RRID:SCR_000074) Copy
http://soap.genomics.org.cn/SOAPfusion.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 22,2022. An open source software tool for fusion discovery with paired-end RNA-Seq reads. The tool follows a different strategy by finding fusions directly and verifying them, differentiating it from all other existing tools by finding the candidate regions and searching for the fusions afterwards.
Proper citation: SOAPfusion (RRID:SCR_000079) Copy
http://www.bioconductor.org/packages/release/bioc/html/timecourse.html
Software functions for data analysis and graphical displays for developmental microarray time course data.
Proper citation: timecourse (RRID:SCR_000077) Copy
http://patchwork.r-forge.r-project.org/
Software tool for analyzing and visualizing allele-specific copy numbers and loss-of-heterozygosity in cancer genomes. The data input is in the format of whole-genome sequencing data which enables characterization of genomic alterations ranging in size from point mutations to entire chromosomes. High quality results are obtained even if samples have low coverage, ~4x, low tumor cell content or are aneuploid. Patchwork takes BAM files as input whereas PatchworkCG takes input from CompleteGenomics files. TAPS performs the same analysis as Patchwork but for microarray data.
Proper citation: Patchwork (RRID:SCR_000072) Copy
http://www.cebitec.uni-bielefeld.de/index.php/2-uncategorised/99-tacoa?highlight=WyJ0YWNvYSJd
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software that can accurately predict the taxonomic origin of genomic fragments from metagenomic data sets by combining the advantages of the k -NN approach with a smoothing kernel function.
Proper citation: TACOA (RRID:SCR_000107) Copy
http://bioinf.scri.ac.uk/tablet/
A lightweight, high-performance graphical viewer for next generation sequence assemblies and alignments.
Proper citation: Tablet (RRID:SCR_000017) Copy
http://www.autoprime.de/AutoPrimeWeb
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16,2023. Server to rapidly design primers for real-time PCR measurement of eukaryotic expression.
Proper citation: AutoPrime (RRID:SCR_000097) Copy
http://sourceforge.net/projects/sirnarules/
An open-source JAVA program that is surprisingly efficient at predicting active siRNAs.
Proper citation: siRNArules (RRID:SCR_000096) Copy
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