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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://sourceforge.net/projects/microanalyzer/
Java tool that performs the preprocessing of Expression and SNPs microarray Affymetrix. The software allows the automatic download and the use of the clustering and visualization software as the Mev 4.0. The tool is equipped by a graphical interface (Swing) that allows to the user to: Create the workspace (files .cel, preferred algorithms , output, libraries to use); Run/save analysis and workspace settings (xml); Efficient download of the libraries (http, ftp, MD5); Customize basic and graphical settings (objects serialization and deserialization). Type of SNPs: Mapping 500k or preceding chips, SNP 5.0, SNP 6.0. Available for 32 or 64 bit systems, and for Windows and Linux Systems.
Proper citation: Micro-Analyzer (RRID:SCR_000394) Copy
http://functsnp.sourceforge.net/
An R package for linking SNPs (Single Nucleotide Polymorphisms) to functional knowledge.
Proper citation: FunctSNP (RRID:SCR_000393) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowStats.html
Software using statistical methods and functionality to analyze flow data that is beyond the basic infrastructure provided by the flowCore package.
Proper citation: flowStats (RRID:SCR_000399) Copy
http://code.google.com/p/d2-tools/
Software toolbox for counting the frequency of K-tuple from sequencing datasets and calculate the dissimilarity.
Proper citation: d2-tools (RRID:SCR_000425) Copy
A user-sponsored molecular visualization software system on an open-source foundation. The software has the capabilities to view, render, animate, export, present and develop three dimensional molecular structures.
Proper citation: PyMOL (RRID:SCR_000305) Copy
http://bioconductor.org/packages/2.12/bioc/html/Clonality.html
Software package for clonality testing providing statistical tests for clonality versus independence of tumors from the same patient based on their loss of heterozygosity (LOH) or genomewide copy number profiles.
Proper citation: Clonality (RRID:SCR_000293) Copy
http://sourceforge.net/projects/limsforproteomi/
Laboratory information management system for proteomics. The software works with 2DPAGE-based proteomics workflow.
Proper citation: LIPAGE (RRID:SCR_000290) Copy
https://github.com/johnomics/RADtools
Software tools for processing RAD Sequencing Illumina reads. Version 1.0 is a pipeline for transforming Illumina reads into candidate genetic markers.
Proper citation: RADtools (RRID:SCR_000324) Copy
https://sites.google.com/site/emesbioinformatics/group-software/nimbl
MATLAB code to quality control and prioritize differentially methylated markers from illumina infinium arrays.
Proper citation: NIMBL (RRID:SCR_000482) Copy
http://www.bioconductor.org/packages/release/bioc/html/iBMQ.html
Software for integrated Bayesian Modeling of eQTL data. It implements a joint hierarchical Bayesian model where all genes and SNPs are modeled concurrently.
Proper citation: iBMQ (RRID:SCR_000481) Copy
http://www.uwyo.edu/buerkle/software/bamova/
Software that implements a Bayesian Analysis of Molecular Variance and different likelihood models for three different types of molecular data (including two models for high throughput sequence data).
Proper citation: bamova (RRID:SCR_000510) Copy
http://sourceforge.net/projects/foursig/
A suite of software programs for analyzing and visualizing 4C-seq data.
Proper citation: fourSig (RRID:SCR_000516) Copy
A collection of cook-book like manuals for various microarray designs. MAGMA is a collaboration between the Norwegian Microarray Consortium NMC and MolMine AS
Proper citation: Mini Analysis Guide for Microarrays (RRID:SCR_000596) Copy
https://github.com/GregoryFaust/samblaster
Software tool to mark duplicates and extract discordant and split reads from SAM files. This fast and flexible program for marking duplicates in read-id grouped paired-end SAM files can also optionally output discordant read pairs and/or split read mappings to separate SAM files, and/or unmapped/clipped reads to a separate FASTQ file. When marking duplicates, samblaster will require approximately 20MB of memory per 1M read pairs.
Proper citation: SAMBLASTER (RRID:SCR_000468) Copy
An efficient software tool for the local alignment of pyrosequencing reads produced by the GS FLX (454) Genome Analyzer technology against a reference genome sequence. The approach explores the characteristics of the data in re-sequencing applications and uses state of the art BWT-based indexing techniques combined with a flexible seed-based approach, leading to a fast and accurate algorithm which needs very little user parameterization. Although initially developed having this specific technology in mind, this software performs equally well on any other platform that can return its sequencing reads in the FASTA, FASTQ or SFF formats, including Illumina, Ion Torrent and Pacific Biosciences technologies.
Proper citation: TAPyR (RRID:SCR_000588) Copy
http://metagenomics.atc.tcs.com/SPHINX/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 1, 2023. Hybrid binning tool that achieves high binning efficiency by utilizing both "compositional" and "similarity" features of the query sequence during the binning process. SPHINX can analyze sequences in metagenomic data sets as rapidly as composition based approaches, but nevertheless has the accuracy and specificity of similarity based algorithms., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: SPHINX (RRID:SCR_000534) Copy
http://open-ms.sourceforge.net/documentation/knime-integration/
A graphical user interface (GUI) for rapid composition of HPLC-MS analysis workflows. Workflow construction is reduced to drag-and-drop of analysis tools and adding connections in between.
Proper citation: TOPPAS (RRID:SCR_000533) Copy
http://mendel.stanford.edu/SidowLab/downloads/gerp/
Software that identifies constrained elements in multiple alignments by quantifying substitution deficits. These deficits represent substitutions that would have occurred if the element were neutral DNA, but did not occur because the element has been under functional constraint. We refer to these deficits as Rejected Substitutions. Rejected substitutions are a natural measure of constraint that reflects the strength of past purifying selection on the element. GERP estimates constraint for each alignment column; elements are identified as excess aggregations of constrained columns. A false-positive rate (which is user-settable) is calculated using "shuffled" alignments in which the order of columns is randomized., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: GERP (RRID:SCR_000563) Copy
http://www.broadinstitute.org/cancer/cga/mutect
Software for the reliable and accurate identification of somatic point mutations in next generation sequencing data of cancer genomes.
Proper citation: MuTect (RRID:SCR_000559) Copy
http://www.ijbcb.org/ESPRITPIPE/php/onlinetool.php
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 9, 2022. Software tool for estimating Species Richness Using 16S rRNA Pyrosequences., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: ESPRIT (RRID:SCR_000552) Copy
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