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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
NanoPipe
 
Resource Report
Resource Website
1+ mentions
NanoPipe (RRID:SCR_016852) NanoPipe analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Web tool for analysis of MinION (ONT) long sequencing reads. Used for analysis of reads generated by the Oxford Nanopore sequencing devices. Provides alignments to any target of interest, alignment statistics and information about polymorphisms. analysis, MinION, long, sequence, read, Oxford Nanopore, alignment, target, statistics, polymorphism, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Muenster; Muenster; Germany
Institute of Bioinformatics Muenster ;
Germany
PMID:30689855 Free, Available for download, Freely Available biotools:NanoPipe https://github.com/IOB-Muenster/nanopipe2, https://bio.tools/NanoPipe SCR_016852 SciCrunch Registry NanoPipe, nanopipe2 2026-09-19 12:55:16 5
DETONATE
 
Resource Report
Resource Website
1+ mentions
DETONATE (RRID:SCR_017035) DETONATE data analysis software, data processing software, sequence analysis software, software application, software resource Software tool to evaluate de novo transcriptome assemblies from RNA-Seq data. Consists of RSEM-EVAL and REF-EVAL packages. RSEM-EVAL is reference-free evaluation method. REF-EVAL is reference based and can be used to compare sets of any kinds of genomic sequences. evaluate, de novo, transcriptome, assembly, RNAseq, data, RSEM-EVAL, REF-EVAL, dataset, genomic, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
NHGRI R01 HG005232;
NLM T15 LM007359
PMID:25608678 Free, Available for download, Freely available biotools:detonate https://bio.tools/detonate SCR_017035 SciCrunch Registry DE novo TranscriptOme rNa-seq Assembly with or without the Truth Evaluation, DETONATE 2026-09-19 12:55:16 2
REDIportal
 
Resource Report
Resource Website
10+ mentions
REDIportal (RRID:SCR_018490) atlas, data or information resource, database, portal, service resource, topical portal Comprehensive database of A-to-I RNA Editing Events. Atlas of A-to-I RNA editing events in human and other organisms. Collection of A-to-I events in body sites of healthy individuals from GTEx project. RNA Editing sites can be searched by genomic region, gene name and other relevant features as tissue of origin. Query results are shown in sortable and downloadable tables in which main characteristics of individual RNA editing events are reported. RNA-Seq and DNA-Seq coverage per site as well as RNA editing levels are provided. A-to-I RNA Editing Events, RNA editing events collection, atlas, database, GTEx project, genomic region, gene name, RNAseq, DNAseq, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CLAIRE
is related to: SIGNOR
Consiglio Nazionale delle Ricerche ;
Italian Ministero dell Istruzione
PMID:27587585 Free, Freely available biotools:rediportal https://bio.tools/rediportal SCR_018490 SciCrunch Registry 2026-09-19 12:55:18 37
MB-GAN
 
Resource Report
Resource Website
1+ mentions
MB-GAN (RRID:SCR_019289) simulation software, software application, software resource Software tool as deep learning simulation framework for simulating realistic microbiome data. Can automatically learn from given microbial abundances and compute simulated abundances that are indistinguishable from it. Metagenomics, deep learning, generative adversarial network, microbiome data simulation, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Texas at Dallas; Texas; USA
DOI:10.1101/863977 Free, Available for download, Freely available biotools:mb-gan https://bio.tools/mb-gan SCR_019289 SciCrunch Registry Microbiome Simulation via Generative Adversarial Network 2026-09-19 12:55:18 1
iontree
 
Resource Report
Resource Website
iontree (RRID:SCR_002813) software resource Software package that provides utility functions to manage and analyse MS2/MS3 fragmentation data from ion trap mass spectrometry. It was designed for high throughput metabolomics data with many biological samples and a large numer of ion trees collected. Tests have been done with data from low-resolution mass spectrometry but could be readily extended to precursor ion based fragmentation data from high resoultion mass spectrometry. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24958264 Free, Freely available, Available for download OMICS_02656, biotools:iontree https://bio.tools/iontree SCR_002813 SciCrunch Registry iontree: Data management and analysis of ion trees from ion-trap mass spectrometry 2026-09-19 12:55:28 0
Composition Profiler
 
Resource Report
Resource Website
10+ mentions
Composition Profiler (RRID:SCR_014630) software resource, web application Web tool for discovery and visualization of differences in amino acid composition. Two samples of amino acid sequences serve as input and a bar chart composed of twenty data points is output. web tool, web application, amino acid, amino acid composition, sequence, bar chart, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:17578581 Source code available, Acknowledgement requested biotools:composition_profiler https://bio.tools/composition_profiler SCR_014630 SciCrunch Registry 2026-09-19 12:55:29 39
CAZy- Carbohydrate Active Enzyme
 
Resource Report
Resource Website
1000+ mentions
CAZy- Carbohydrate Active Enzyme (RRID:SCR_012909) CAZy data or information resource, database Database that describes the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds. This specialist database is dedicated to the display and analysis of genomic, structural and biochemical information on Carbohydrate-Active Enzymes (CAZymes). CAZy data are accessible either by browsing sequence-based families or by browsing the content of genomes in carbohydrate-active enzymes. New genomes are added regularly shortly after they appear in the daily releases of GenBank. New families are created based on published evidence for the activity of at least one member of the family and all families are regularly updated, both in content and in description. An original aspect of the CAZy database is its attempt to cover all carbohydrate-active enzymes across organisms and across subfields of glycosciences. One can search for CAZY Family pages using the Protein Accession (Genpept Accession, Uniprot Accession or PDB ID), Cazy family name or EC number. In addition, genomes can be searched using the NCBI TaxID. This search can be complemented by Google-based searches on the CAZy site. carbohydrate, carbohydrate-binding, carbohydrate binding module, carbohydrate esterase, catalytic binding, glycosidic bond, glycosidic hydrolase, glycosyl transferase, polysaccharide lyase, enzyme class, enzyme, module, genome, virus, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: OMICtools
has parent organization: Aix-Marseille University; Provence-Alpes-Cote d'Azur; France
PMID:24270786 r3d100012321, biotools:cazy, OMICS_01677, nif-0000-02642, SCR_012935 https://bio.tools/cazy SCR_012909 SciCrunch Registry Carbohydrate-Active enZYme, Carbohydrate-Active enZYmes Database 2026-09-19 12:55:31 2435
ProP Server
 
Resource Report
Resource Website
50+ mentions
ProP Server (RRID:SCR_014936) software resource, web application Web application which predicts arginine and lysine propeptide cleavage sites in eukaryotic protein sequences using an ensemble of neural networks. Furin-specific prediction is the default. It is also possible to perform a general proprotein convertase prediction. web application, prediction, arginine, lysine, cleavage, propeptide, eukaryotic, protein, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1093/protein/gzh013 Open source biotools:prop, BioTools:prop https://bio.tools/prop, https://bio.tools/prop, https://bio.tools/prop SCR_014936 SciCrunch Registry ProP, ProP 1.0 Server, ProP 1.0 2026-09-19 12:55:31 78
GeneWise
 
Resource Report
Resource Website
1000+ mentions
GeneWise (RRID:SCR_015054) software resource, web application Gene alignment tool from the EBI which predicts gene structure using similar protein sequences. See also the associated GenomeWise tool. gene alignment, dna sequence, protein sequence, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: European Bioinformatics Institute
PMID:15123596 Freely available, Available for download biotools:wise https://bio.tools/wise SCR_015054 SciCrunch Registry 2026-09-19 12:55:31 1079
mlgt
 
Resource Report
Resource Website
mlgt (RRID:SCR_001211) mlgt data processing software, software application, software resource Software for processing and analysis of high throughput (Roche 454) sequences generated from multiple loci and multiple biological samples. Sequences are assigned to their locus and sample of origin, aligned and trimmed. Where possible, genotypes are called and variants mapped to known alleles. roche, windows, os x, genotype, variant, allele, high throughput sequencing, locus, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Manchester; Manchester; United Kingdom
THIS RESOURCE IS NO LONGER IN SERVICE BioTools:mlgt, OMICS_02131, biotools:mlgt https://bio.tools/mlgt, https://bio.tools/mlgt, https://bio.tools/mlgt SCR_001211 SciCrunch Registry Multi-Locus Geno-Typing, mlgt: Multi-Locus Geno-Typing 2026-09-19 12:55:49 0
SOAP
 
Resource Report
Resource Website
100+ mentions
SOAP (RRID:SCR_000689) SOAP, data processing software, software application, software resource Software package that provides full solution to next generation sequencing data analysis consisting of an alignment tool (SOAPaligner/soap2), a re-sequencing consensus sequence builder (SOAPsnp), an indel finder ( SOAPindel ), a structural variation scanner ( SOAPsv ), a de novo short reads assembler ( SOAPdenovo ), and a GPU-accelerated alignment tool for aligning short reads with a reference sequence. (SOAP3/GPU)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, next generation sequencing, alignment, short read, bio.tools lists: SOAPfusion
lists: SOAPfuse
lists: SOAPnuke
lists: GapCloser
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: BGI; Shenzhen; China
is parent organization of: SOAP3
is parent organization of: SOAPaligner/soap2
PMID:18227114 THIS RESOURCE IS NO LONGER IN SERVICE nlx_154652, biotools:soap https://bio.tools/soap SCR_000689 SciCrunch Registry SOAP: short oligonucleotide alignment program, Short Oligonucleotide Analysis Package 2026-09-19 12:55:49 403
iDASH
 
Resource Report
Resource Website
1+ mentions
iDASH (RRID:SCR_003524) iDASH data or information resource, organization portal, portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 6, 2023. National Center for Biomedical Computing (NCBC) that develops new algorithms, opensource tools, computational infrastructure, and services for biomedical and behavioral researchers nationwide to promote the secure sharing and consuming of biomedical and behavioral resources (software, data, and computing systems) with iDASH collaborators. The center addresses fundamental challenges to research progress by providing a secure, privacypreserving environment in which researchers can analyze genomic, transcriptomic, clinical, behavioral, and social data relevant to health. Three driving biological projects in iDASH (Molecular Phenotyping of Kawasaki Disease, Post-Marketing Surveillance of Hematologic Medications, and Individualized Intervention to Enhance Physical Activity) span the molecular-individualpopulation spectrum, and they will motivate, inform, and support tool development. iDASH will collaborate with other NCBCs and will disseminate tools via annual workshops, presentations at major conferences, and scientific publications. data sharing, computing, biomedical, behavior, molecular, phenotyping, kawasaki disease, hematologic medication, individualized intervention, physical activity, phenotype, data set, image, cyberinfrastructure, schema, domain model, algorithm, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: DataCite
is related to: National Centers for Biomedical Computing
is related to: NIH Data Sharing Repositories
is related to: National Centers for Biomedical Computing
has parent organization: University of California at San Diego; California; USA
has parent organization: University of California; California; USA
NIH Roadmap for Bioinformatics and Computational Biology ;
NHLBI U54 HL108460
PMID:22081224 THIS RESOURCE IS NO LONGER IN SERVICE https://api.datacite.org/dois?prefix=10.15147, biotools:iDASH, nif-0000-38239 https://bio.tools/iDASH SCR_003524 SciCrunch Registry iDASH Repository, Integrating Data for Analysis Anonymization and SHaring 2026-09-19 12:55:52 2
biobambam
 
Resource Report
Resource Website
50+ mentions
biobambam (RRID:SCR_003308) data processing software, software application, software resource Software tools for read pair collation based algorithms on BAM files including * bamcollate2: reads BAM and writes BAM reordered such that alignment or collated by query name * bammarkduplicates: reads BAM and writes BAM with duplicate alignments marked using the BAM flags field * bammaskflags: reads BAM and writes BAM while masking (removing) bits from the flags column * bamrecompress: reads BAM and writes BAM with a defined compression setting. This tool is capable of multi-threading. * bamsort: reads BAM and writes BAM resorted by coordinates or query name * bamtofastq: reads BAM and writes FastQ; output can be collated or uncollated by query name standalone software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1186/1751-0473-9-13 Free, Available for download, Freely available biotools:biobambam, OMICS_04664 https://bio.tools/biobambam, https://sources.debian.org/src/biobambam2/ SCR_003308 SciCrunch Registry 2026-09-19 12:55:52 65
Phenoscape
 
Resource Report
Resource Website
10+ mentions
Phenoscape (RRID:SCR_003799) Phenoscape data or information resource, portal Project to create a scalable infrastructure that enables linking phenotypes across different fields of biology by the semantic similarity of their descriptions. phenotype, bio.tools is listed by: Debian
is listed by: bio.tools
is parent organization of: Teleost Anatomy Ontology
is parent organization of: Vertebrate Taxonomy Ontology
is parent organization of: Phenoscape Knowledgebase
NSF DBI-1062404;
NSF DBI-1062542;
NSF BDI-0641025;
NSF EF-0905606;
NSF EF-0423641
biotools:Phenoscape, nlx_158096 https://bio.tools/Phenoscape SCR_003799 SciCrunch Registry 2026-09-19 12:55:52 10
FASTX-Toolkit
 
Resource Report
Resource Website
1000+ mentions
FASTX-Toolkit (RRID:SCR_005534) data processing software, software application, software resource, software toolkit Software tool as collection of command line tools for Short-Reads FASTA/FASTQ files preprocessing. Short reads, FASTA file, FASTQ file, preprocessing, command line tools, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Cold Spring Harbor Laboratory
SCR_019035, SCR_015042, biotools:fastx-toolkit, OMICS_01045 https://github.com/agordon/fastx_toolkit, https://bio.tools/fastx-toolkit SCR_005534 SciCrunch Registry FASTQ/A short-reads pre-processing tools 2026-09-19 12:55:55 2864
Mammalian Gene Collection
 
Resource Report
Resource Website
10+ mentions
Mammalian Gene Collection (RRID:SCR_007024) MGC biomaterial supply resource, cell repository, material resource NIH initiative project to provide full-length open reading frame (FL-ORF) clones for human, mouse, and rat genes, cow. MGC cDNA clones were obtained by screening of cDNA libraries, by transcript-specific RT-PCR cloning, and by DNA synthesis of cDNA inserts. All MGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of MGC project in March 2009, GenBank records of MGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which they have MGC clones will likely change in future, users planning to order MGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as the UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene). cell line, cdna, frozen, clone, vector, gene, open reading frame, sequence, expressed sequence tag, bio.tools, FASEB list is listed by: One Mind Biospecimen Bank Listing
is listed by: bio.tools
is listed by: Debian
is related to: One Mind Biospecimen Bank Listing
is related to: NIDDK Information Network (dkNET)
is related to: ATCC
is related to: GenBank
is related to: Invitrogen Clones
is related to: Open Biosystems
is related to: Zebrafish Gene Collection
has parent organization: National Cancer Institute
NIH Blueprint for Neuroscience Research Free, Freely available biotools:mammalian_gene_collection, nif-0000-00195 https://bio.tools/mammalian_gene_collection SCR_007024 SciCrunch Registry Mammalian Gene Collection 2026-09-19 12:55:56 46
Sickle
 
Resource Report
Resource Website
1000+ mentions
Sickle (RRID:SCR_006800) Sickle data processing software, software application, software resource Software tool for windowed adaptive trimming for fastq files using quality. Supports quality values like Illumina, Solexa, and Sanger. Takes the quality values and slides a window across them whose length is 0.1 times the length of the read. bio.tools, windowed, adaptive, trimming, FASTQ, quality, value, read is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available OMICS_01077, biotools:sickle, SCR_016901 https://bio.tools/sickle, https://sources.debian.org/src/sickle/ SCR_006800 SciCrunch Registry sickle - A windowed adaptive trimming tool for FASTQ files using quality 2026-09-19 12:55:56 1664
SeqTrace
 
Resource Report
Resource Website
50+ mentions
SeqTrace (RRID:SCR_005580) SeqTrace data processing software, software application, software resource A software application for viewing and processing DNA sequencing chromatograms (trace files) that makes it easy to quickly generate high-quality finished sequences from a large number of trace files. SeqTrace can automatically identify, align, and compute consensus sequences from matching forward and reverse traces, filter low-quality base calls, and perform end trimming of finished sequences. The finished DNA sequences can then be exported to common sequence file formats, such as FASTA. SeqTrace also includes a full-featured trace file viewer and editor. You can view your sequencing chromatograms at a variety of scales and zoom levels, simultaneously view matching forward and reverse traces, edit the called bases, and export individual DNA sequences as well as forward/reverse alignments. SeqTrace supports popular trace file formats, including ABIF, SCF, and ZTR. dna sequencing trace file, dna sequencing, trace file, trace, python, gtk, chromatogram, graphic, sequence analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
has parent organization: University of Colorado Boulder; Colorado; USA
PMID:22942788 GNU General Public License, v3 OMICS_01021, biotools:seqtrace https://bio.tools/seqtrace SCR_005580 SciCrunch Registry Seqtrace - User-friendly software for viewing and processing DNA sequencing trace files 2026-09-19 12:55:55 64
RESCUE-ESE
 
Resource Report
Resource Website
50+ mentions
RESCUE-ESE (RRID:SCR_008496) data or information resource, database, organization portal, portal Specific short oligonucleotide sequences that enhance pre-mRNA splicing when present in exons, termed exonic splicing enhancers (ESEs), play important roles in constitutive and alternative splicing (ESE References). A hybrid computational/experimental method, RESCUE-ESE, was recently developed for identifying sequences with ESE activity. In this approach, specific hexanucleotide sequences are identified as candidate ESEs on the basis that they have both significantly higher frequency of occurrence in exons than in introns and also significantly higher frequency in exons with weak (non-consensus) splice sites than in exons with strong (consensus) splice sites. Representative hexamers from ten different classes of candidate ESEs, together with 6 or 7 bases of flanking sequence context on each side, were introduced into a weak (poorly spliced) exon in a splicing reporter construct. These reporter minigenes were then transfected into cultured cells, where they are transcribed and spliced, and the relative level of inclusion of the test exon was assayed by quantitative (radio-labeled) RT-PCR. Point mutants of these sequences were also analyzed to confirm the precise motifs responsible for ESE activity. The RESCUE-ESE approach identified 238 hexamers as candidate ESEs using a large database of human genes of known exon-intron structure containing over 30,000 nonredudant exons. In more recent analyses by Yeo et al., the RESCUE-ESE approach was utilized to predict hexamers as candidate ESEs in other vertebrate genes, namely, Fugu rubipes, Zebrafish and Mouse. This allows the identification of motifs that are conserved in vertebrates. This web server allows a sequence to be checked for presence of these candidate ESE hexamers. bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
biotools:rescue-ese, nif-0000-31403 https://bio.tools/rescue-ese http://genes.mit.edu/burgelab/rescue-ese/ SCR_008496 SciCrunch Registry RESCUE-ESE 2026-09-19 12:55:58 96
HCLUST
 
Resource Report
Resource Website
1000+ mentions
HCLUST (RRID:SCR_009154) HCLUST software application, software resource Software application that is a simple clustering method that can be used to rapidly identify a set of tag SNP's based upon genotype data (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, r, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:h-clust, SCR_009102, nlx_154195, nlx_154331 https://bio.tools/h-clust SCR_009154 SciCrunch Registry R/HCLUST 2026-09-19 12:55:59 1460

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