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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
ProtParam Tool
 
Resource Report
Resource Website
5000+ mentions
ProtParam Tool (RRID:SCR_018087) analysis service resource, data analysis software, data processing software, production service resource, sequence analysis software, service resource, software application, software resource Software tool to calculate various physicochemical parameters for given protein stored in Swiss-Prot or TrEMBL or for user entered protein sequence. Protein can either be pecified as Swiss-Prot/TrEMBL accession number or ID, or in form of raw sequence. Computed parameters include molecular weight, theoretical pI, amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, aliphatic index and grand average of hydropathicity. Calculate phycicochemical parameter, protein, Swiss-Prot, TrEMBL, protein sequence, molecular weight, theortical pl, amino acid composition, atomic composition, extinction coefficient, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
NHGRI U01 HG02712;
Swiss Federal Government through Federal Office of Education and Science
PMID:10027275 Free, Freely available biotools:protparam https://bio.tools/protparam SCR_018087 SciCrunch Registry ProtParam 2026-10-10 12:40:09 7206
pepwheel
 
Resource Report
Resource Website
1+ mentions
pepwheel (RRID:SCR_018398) data access protocol, service resource, software resource, web service Web tool to visualise protein sequences as helices. Draws helical wheel diagram for protein sequence. EMBOSS pepwheel displays peptide sequences in helical representation. Computational proteomics, data analysis pipeline, label free quantification, mass spectrometry, quantitative proteomics, visualise protein sequence, helical wheel diagram, peptice sequence display, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: EMBOSS
works with: Proteome Discoverer
Free, Freely available biotools:pepwheel https://bio.tools/pepwheel SCR_018398 SciCrunch Registry 2026-10-10 12:40:54 2
TDimpute
 
Resource Report
Resource Website
1+ mentions
TDimpute (RRID:SCR_018306) data analysis software, data processing software, software application, software resource Software tool to transfer learning based deep neural network to impute missing gene expression data from DNA methylation data. Transfer learning; gene expression prediction; DNA methylation; TCGA, neural network, missing gene expression, data, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/803692 Free, Available for download, Freely available biotools:tDimpute, BioTools:TDimpute https://bio.tools/TDimpute, https://bio.tools/TDimpute, https://bio.tools/TDimpute SCR_018306 SciCrunch Registry 2026-10-10 12:40:12 1
Protein Interactions Calculator
 
Resource Report
Resource Website
10+ mentions
Protein Interactions Calculator (RRID:SCR_018574) analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Web server for inter residue interaction calculations in single site. Determines accessible surface area and residue depth, which is distance of residue from surface of protein. Recognizes specific kind of interactions, such as apolar–apolar residue interactions or ionic interactions, that are formed between buried or exposed residues or near surface or deep inside. Recognizes interactions including disulphide bonds, hydrophobic interactions, ionic interactions, hydrogen bonds, aromatic- aromatic interactions, aromatic-sulphur interactions and cation interactions within protein or between proteins in complex. Protein interaction, interaction calculation, single site, accessible surface are, residue depth, protein surface, residue distance, residue interaction, protein complex, bio.tools is listed by: Debian
is listed by: bio.tools
Department of Biotechnology Government of India PMID:17584791 Free, Freely available biotools:pic https://bio.tools/pic http://crick.mbu.iisc.ernet.in/~PIC SCR_018574 SciCrunch Registry 2026-10-10 12:40:55 34
LRPath
 
Resource Report
Resource Website
1+ mentions
LRPath (RRID:SCR_018572) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web tool to perform gene set enrichment testing. Used to test for predefined biologically relevant gene sets that contain more significant genes from experimental dataset than expected by chance. Logistic regression approach for identifying enriched biological groups in gene expression data. Gene, map, gene set, gene set testing, identifying enriched biologically group, gene expression data, gene expression, data, bio.tools is listed by: bio.tools
is listed by: Debian
NHGRI R01 HG003749;
NIDA U54 DA021519;
NIEHS P30 ES06096;
NIEHS U01 ES015675;
NLM R01 LM008106
PMID:19038984 Free, Freely available biotools:lrpath https://bio.tools/lrpath SCR_018572 SciCrunch Registry 2026-10-10 12:40:16 4
Plant Co-expression Annotation Resource
 
Resource Report
Resource Website
1+ mentions
Plant Co-expression Annotation Resource (RRID:SCR_018429) Plantannot data access protocol, data or information resource, service resource, software resource, web service Webserver for identifying targets for genetically modified crop breeding pipelines. Used to find proteins that have no annotation or function assigned and could be related to molecular mechanisms regarding abiotic stresses in plants. System aggregates orthology, coexpression networks and genomic data to filter genomes of plants downloaded from Phytozome and NCBI and select candidate proteins in that regard. Omics, plant, annotation, function, breeding, genetically modified crops, abiotic stress in plant, plant genome, plant genomic data, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Phytozome
is related to: NCBI
is related to: Machado
Embrapa DOI:10.1101/2020.05.22.110510 Free, Freely available biotools:plantannot https://www.machado.cnptia.embrapa.br/plantannot2, https://bio.tools/plantannot SCR_018429 SciCrunch Registry Plantannot v2 2026-10-10 12:40:14 1
GalaxyWEB
 
Resource Report
Resource Website
100+ mentions
GalaxyWEB (RRID:SCR_018558) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web server for protein structure prediction and refinement. Used to predict protein structure from sequence by template based modeling. Used for refinement after providing starting model structure and locations of loops or termini to be refined. Protein structure prediction, protein structure refinement, protein sequence, template based modeling, model structure, loop location, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Seoul National University; Seoul; South Korea
Ministry of Land ;
Transport and Maritime Affairs of Korea ;
National Research Foundation of Korea ;
Seoul National University
PMID:22649060 Free, Freely available biotools:galaxyweb https://bio.tools/galaxyweb SCR_018558 SciCrunch Registry 2026-10-10 12:40:55 231
MaxAlign
 
Resource Report
Resource Website
10+ mentions
MaxAlign (RRID:SCR_018552) analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Web tool for maximizing usable data in alignment. Maximizes number of characters that are present in gap free columns alignment area by selecting optimal subset of sequences. Removes sequences with many gaps in post process of alignments in order to improve alignment area. Maximizing data, post process alignment, gap free column alignment area, sequence subset selection, improve alignment area, bio.tools is listed by: Debian
is listed by: bio.tools
Foundation for Science and Technology Portuguese Ministry of Science. PMID:17725821 Free, Available for download, Freely available biotools:maxalign https://bio.tools/maxalign SCR_018552 SciCrunch Registry MaxAlign 1.1, MaxAlign 1.1 Server 2026-10-10 12:40:21 11
HPEPDOCK Server
 
Resource Report
Resource Website
50+ mentions
HPEPDOCK Server (RRID:SCR_018561) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web server for blind peptide protein docking based on hierarchical algorithm. Blind peptide-protein docking by fast modeling of peptide conformations and global sampling of binding orientations. Blind peptide protein docking, peptide conformation modeling, global sampling, blind orientation, protein, modeling, docking, bio.tools is listed by: bio.tools
is listed by: Debian
Huazhong University of Science and Technology ;
National Key Research and Development Program of China ;
National Natural Science Foundation of China
PMID:29746661 Free, Freely available biotools:hpepdock https://bio.tools/hpepdock SCR_018561 SciCrunch Registry 2026-10-10 12:40:16 73
GalaxyRefine
 
Resource Report
Resource Website
100+ mentions
GalaxyRefine (RRID:SCR_018531) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web server for protein structure prediction, refinement, and related methods. First rebuilds side chains and performs side-chain repacking and subsequent overall structure relaxation by molecular dynamics simulation. Protein structure prediction, protein, structure prediction, protein structure, molecular dynamics simulation, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Seoul National University; Seoul; South Korea
National Research Foundation of Korea ;
Seoul National University.
PMID:23737448 biotools:galaxyrefine https://bio.tools/galaxyrefine SCR_018531 SciCrunch Registry 2026-10-10 12:40:21 316
EpiEstim
 
Resource Report
Resource Website
10+ mentions
EpiEstim (RRID:SCR_018538) data analysis software, data processing software, software application, software resource, software toolkit Framework and software to estimate time varying reproduction numbers during epidemics. Tools to quantify transmissibility throughout epidemic from analysis of time series of incidence. Used to estimate time varying instantaneous reproduction numbers from incidence time series. Estimate time varying, reproduction number, epidemics, quantify transmissibility, time series analysis, reproductionc number analysis, incidence time series, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
United Kingdom Medical Research Council PMID:24043437 Free, Available for download, Freely available biotools:EpiEstim https://bio.tools/EpiEstim SCR_018538 SciCrunch Registry Estimate Time Varying Reproduction Numbers from Epidemic Curves 2026-10-10 12:40:55 35
betaVAEImputation
 
Resource Report
Resource Website
1+ mentions
betaVAEImputation (RRID:SCR_018730) data analysis software, data processing software, software application, software resource Software tool as deep learning framework based on variational autoencoder to impute missing values in transcriptome and methylome data analysis. Genomic data, handling missing data, deep learning framework, variational autoencoder, imputing missing values, transcriptome, methylome, data analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:betavaeimputation https://bio.tools/betavaeimputation SCR_018730 SciCrunch Registry 2026-10-10 12:40:19 2
CRISPR-ERA
 
Resource Report
Resource Website
10+ mentions
CRISPR-ERA (RRID:SCR_018710) data access protocol, service resource, software resource, web service Software comprehensive design tool for CRISPR mediated gene editing, repression and activation. Fast and comprehensive guide RNA design tool for genome editing, repression and activation. Used for automated genome wide sgRNA design. Design tool, CRISPR mediated gene editing, gene repression, gene activation, guide RNA design, genome, automated genome, sgRNA design, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Stanford University; Stanford; California
FANEDD ;
NIDA R01 DA036858;
NIDCR ;
NIH Office of The Director ;
NIH Office of the Director OD017887;
NSFC
PMID:26209430 Free, Freely available biotools:CRISPR-ERA https://bio.tools/CRISPR-ERA SCR_018710 SciCrunch Registry CRISP-Editing, Repression and Activation 2026-10-10 12:40:25 13
MiXCR
 
Resource Report
Resource Website
50+ mentions
MiXCR (RRID:SCR_018725) data analysis software, data processing software, software application, software resource Software tool to processes big immunome data from raw sequences to quantitated clonotypes by MiLaboratory LLC. Universal software for analysis of T- and B-cell receptor repertoire high throughput sequencing data. Software for comprehensive adaptive immunity profiling. Process immunome data, raw sequence, quantitated clonotype, B cell receptor, sequencing data analysis, T cell receptor, high throughput sequencing data, adaptive immunity profiling, MiLaboratory, bio.tools is listed by: Debian
is listed by: bio.tools
Russian Science Foundation PMID:25924071 Restricted biotools:MiXCR, BioTools:MiXCR https://github.com/milaboratory/mixcr, https://bio.tools/MiXCR, https://bio.tools/MiXCR, https://bio.tools/MiXCR SCR_018725 SciCrunch Registry 2026-10-10 12:40:57 73
BcForms
 
Resource Report
Resource Website
BcForms (RRID:SCR_018654) data access protocol, software resource, software toolkit, web service Software toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks. Web tool for describing molecular structure of macromolecular complexes, including non canonical monomeric forms, circular topologies, and crosslinks. Describes semantic meaning of whole cell computational models. Molecular structure description, molecular complex, atom, bond, protein, complex, modification, crosslinked residue, semantic meaning description, bio.tools is used by: BpForms
is used by: ObjTables
is listed by: Debian
is listed by: bio.tools
is related to: BpForms
NIBIB P41 EB023912;
NIGMS R35 GM119771;
NSF 1649014
PMID:32423472 Free, Freely available biotools:bcforms https://bio.tools/bcforms SCR_018654 SciCrunch Registry 2026-10-10 12:40:18 0
precrec
 
Resource Report
Resource Website
1+ mentions
precrec (RRID:SCR_018659) data analytics software, software application, software resource, software toolkit Software R package for fast and accurate precision recall and ROC curve calculations. Calculates accurate precision recall and Receiver Operator Characteristics curves. Precision recall, receiver operator characteristics, receiver operator characteristics curve, curve calculations, precision recall calculation, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CRAN
DOI:10.1093/bioinformatics/btw570 Free, Freely available biotools:precrec https://bio.tools/precrec SCR_018659 SciCrunch Registry 2026-10-10 12:40:18 2
Datanator
 
Resource Report
Resource Website
1+ mentions
Datanator (RRID:SCR_018651) application programming interface, data access protocol, data or information resource, database, software resource, web application Software toolkit for discovering data needed to build, calibrate, and validate mechanistic models of cells. Integrated database of molecular data for quantitatively modeling cellular behavior. Web application for identifying relevant data for modeling specific organism in specific environmental condition. Data discovering, cell model, model cellular biochemistry, modeling specific organism, specific environmental condition, genomics, proteomics, epigenomics, metabolomics, system biology, bio.tools uses: BpForms
is listed by: Debian
is listed by: bio.tools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
NIBIB P41 EB023912;
NIGMS R35 GM119771
DOI:10.1101/2020.08.06.240051 Free, Freely available biotools:datanator, r3d100013339 https://github.com/karrlab/datanator, https://bio.tools/datanator, https://doi.org/10.17616/R31NJMSB SCR_018651 SciCrunch Registry 2026-10-10 12:40:18 2
PrognoScan
 
Resource Report
Resource Website
100+ mentions
PrognoScan (RRID:SCR_018740) analysis service resource, data or information resource, database, production service resource, service resource Database for meta analysis of prognostic value of genes from server at Kyushu Institute of Technology. Collection of publicly available cancer microarray datasets with clinical annotation, as well as tool for assessing biological relationship between gene expression and prognosis. Provides platform for evaluating potential tumor markers and therapeutic targets. Kyushu Institute of Technology, meta analysis, prognostic gene value, cancer microarray dataset, clinical annotation, gene expression, tumor marker, therapeutic target, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
PMID:19393097 Free, Freely available SCR_018741, biotools:prognoscan http://dna00.bio.kyutech.ac.jp/PrognoScan/index.html, https://bio.tools/prognoscan SCR_018740 SciCrunch Registry 2026-10-10 12:40:57 461
Evolutionary Couplings Server
 
Resource Report
Resource Website
10+ mentions
Evolutionary Couplings Server (RRID:SCR_018745) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web server provides functional and structural information about proteins from their evolutionary record using methods from statistical physics. Computes evolutionary couplings from sequence alignments and predicts 3D structure for your protein of interest. Allows to run former EVcouplings, EVmutation, EVfold and EVcomplex jobs. Coevolutionary sequence analysis, evolutionary coupling, protein sequence, RNA sequence alignment, predict protein structure, evolutionary sequence covariantion, 3D protein structure prediction, , bio.tools is listed by: bio.tools
is listed by: Debian
DOE CSGF fellowship ;
NIGMS R01 GM106303;
NSF GRFP DGE1144152
PMID:30304492 Free, Freely available biotools:EVcouplings https://github.com/debbiemarkslab/evcouplings, https://bio.tools/EVcouplings SCR_018745 SciCrunch Registry EVcouplings 2026-10-10 12:40:19 26
StoatyDive
 
Resource Report
Resource Website
1+ mentions
StoatyDive (RRID:SCR_018796) data analysis software, data processing software, software application, software resource Software tool to evaluate and classify predicted peak profiles to assess binding specificity of protein to its targets. Can be used for sequencing data such as CLIP-seq or ChIP-Seq, or any other type of peak profile data. Evaluate predicted peak profile, classify predicted peak profile, assess binding specificity, protein-target specificity, sequencing data, CLIP-seq data, CHIP-Seq data, peak profile data, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available SCR_018800, biotools:StoatyDive https://bio.tools/StoatyDive SCR_018796 SciCrunch Registry 2026-10-10 12:40:27 1

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