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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
CIBERSORT
 
Resource Report
Resource Website
1000+ mentions
CIBERSORT (RRID:SCR_016955) data analytics software, software application, software resource Software tool to provide an estimation of the abundances of member cell types in a mixed cell population, using gene expression data. Used for characterizing cell composition of complex tissues from their gene expression profiles, large scale analysis of RNA mixtures for cellular biomarkers and therapeutic targets. estimation, abundance, cell, type, mixed, population, gene, expression, data, tissue, complex, analysis, RNA, biomarker, therapeutic, target, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Stanford University; Stanford; California
B&J Cardan Oncology Research Fund ;
Damon Runyon Cancer Research Foundation ;
Doris Duke Charitable Foundation ;
Ludwig Institute for Cancer Research ;
NCI T32 CA09302;
NCI U01 CA154969;
NIAID U19 AI090019;
Siebel Stem Cell Institute ;
Thomas and Stacey Siebel Foundation ;
US Department of Defense
PMID:25822800 Not freely available for download or distribution, Available for non commercial users, Registration required biotools:CIbERSORt https://bio.tools/CIBERSORT SCR_016955 SciCrunch Registry 2026-09-26 02:19:28 1908
PhyML
 
Resource Report
Resource Website
5000+ mentions
PhyML (RRID:SCR_014629) software resource, source code, web application Web phylogeny server based on the maximum-likelihood principle. phylogenic software, phylogeny, maximum likelihood, web server, bio.tools is used by: ProtTest
is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
works with: PAML
DOI:10.1093/molbev/msq060 Public server, Source code is available on request biotools:phyml, OMICS_04241 https://bio.tools/phyml, https://sources.debian.org/src/phyml/ SCR_014629 SciCrunch Registry 2026-09-26 02:19:24 7951
QmRLFS-finder
 
Resource Report
Resource Website
10+ mentions
QmRLFS-finder (RRID:SCR_014584) data analytics software, software application, software resource A software which predicts R-loop Forming Sequences (RLFSs) in nucleic acid sequences based on the experimentally supported structural models of RLFSs. The tool identifies and visualizes RLFS coordinates from natural or artificial DNA or RNA input sequences and creates standard-compliant output files for later annotation and analysis. r-loop, r loop, rlf, rlfs, dna, rna, input sequences, output files, annotation, analysis, bio.tools uses: UCSC Genome Browser
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
Singapore Agency for Science Technology and Research PMID:26400173
PMID:25883153
Open Source biotools:qmrlfs-finder https://omictools.com/qmrlfs-finder-tool, https://bio.tools/qmrlfs-finder SCR_014584 SciCrunch Registry QmRLFS finder 2026-09-26 02:19:26 16
FunRich: Functional Enrichment analysis tool
 
Resource Report
Resource Website
100+ mentions
FunRich: Functional Enrichment analysis tool (RRID:SCR_014467) data analytics software, software application, software resource, standalone software A software tool used for functional enrichment and interaction network analysis of genes and proteins. Users can search against a default background database or load customized database. The results can be depicted as venn, bar, column, pie and doughnut charts. network analysis, background database, charts, data analytics software, standalone software, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
PMID:25921073
PMID:26149235
Public, Open Source biotools:funrich https://bio.tools/funrich SCR_014467 SciCrunch Registry 2026-09-26 02:19:24 431
topGO
 
Resource Report
Resource Website
1000+ mentions
topGO (RRID:SCR_014798) software resource, software toolkit Software package which provides tools for testing GO terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied. r, go, go graph, local similarities, software tool, software package, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
works with: Gene Ontology
is hosted by: Bioconductor
Available for download biotools:topgo https://bio.tools/topgo SCR_014798 SciCrunch Registry 2026-09-26 02:19:25 3080
Clinotator
 
Resource Report
Resource Website
1+ mentions
Clinotator (RRID:SCR_016054) software application, software resource Software that performs clinical interpretation of ambiguous ClinVar annotations. This software takes batches of variants as input and queries NCBI eutilities to generate scoring metrics. clinical, age, weight, score, metric, vcf, python, nbci, annotation, variant, scoring, bio.tools is listed by: bio.tools
is listed by: Debian
Free biotools:clinotator https://bio.tools/clinotator SCR_016054 SciCrunch Registry clinotator.py 2026-09-26 02:19:26 2
DANPOS2
 
Resource Report
Resource Website
100+ mentions
DANPOS2 (RRID:SCR_015527) software resource, software toolkit Software toolkit with various functions for the analysis of nucleosome and protein occupancy by sequencing. nucleosome analysis, protein analysis, protein occupancy, bio.tools uses: Dpos
is listed by: bio.tools
is listed by: Debian
Available for download, Different versions are available for download biotools:danpos https://bio.tools/danpos SCR_015527 SciCrunch Registry DANPOS 2026-09-26 02:19:26 114
PREDDIMER
 
Resource Report
Resource Website
10+ mentions
PREDDIMER (RRID:SCR_011963) PREDDIMER analysis service resource, data analysis service, production service resource, service resource Prediction tool to reconstruct putative dimer conformations for given sequences of transmembrane protein fragments, which are considered as ideal alpha-helices. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24202542 Free OMICS_01614, biotools:preddimer https://bio.tools/preddimer SCR_011963 SciCrunch Registry PREDDIMER - Prediction tool for an ensemble of transmembrane ?-helical dimer conformations 2026-09-26 02:18:47 15
Cube-DB
 
Resource Report
Resource Website
1+ mentions
Cube-DB (RRID:SCR_013233) Cube-DB data or information resource, database Cube-DB is a database of pre-evaluated conservation and specialization scores for residues in paralogous proteins belonging to multi-member families of human proteins. Protein family classification follows (largely) the classification suggested by HUGO Gene Nomenclature Committee. Sets of orhtologous protein sequences were generated by mutual-best-hit strategy using full vertebrate genomes available in Ensembl. The scores, described on documentation page, are assigned to each individual residue in a protein, and presented in the form of a table (html or downloadable xls formats) and mapped, when appropriate, onto the related structure (Jmol, Pymol, Chimera). protein, functional divergence, vertebrate, genome, ortholog, protein sequence, data set, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioinformatics Institute; Singapore; Singapore
PMID:22139934 nlx_149432, biotools:cube-db https://bio.tools/cube-db SCR_013233 SciCrunch Registry Cube-DB: Detection of Functional Divergence in Human Protein Families 2026-09-26 02:18:50 3
Open Trials
 
Resource Report
Resource Website
1+ mentions
Open Trials (RRID:SCR_015570) data or information resource, database Database that contains data such as registry entries, portions of regulatory documents describing individual trials, structured data on methods and results, and researchers and papers from and/or related to clinical trials. The initiative aims to locate, match, and share all publicly accessible data and documents, on all trials conducted, on all medicines and other treatments, globally. clinical trial, clinical trial database, clinical trial data, open database, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Oxford; Oxford; United Kingdom
Laura and John Arnold Foundation ;
Wellcome Trust ;
World Health Organisation ;
West of England Academic Health Science Network
Open source biotools:opentrials https://bio.tools/opentrials SCR_015570 SciCrunch Registry 2026-09-26 02:18:55 3
Genome Aggregation Database
 
Resource Report
Resource Website
5000+ mentions
Genome Aggregation Database (RRID:SCR_014964) gnomAD data or information resource, database Database that aggregates exome and genome sequencing data from large-scale sequencing projects. The gnomAD data set contains individuals sequenced using multiple exome capture methods and sequencing chemistries. Raw data from the projects have been reprocessed through the same pipeline, and jointly variant-called to increase consistency across projects. database, genome, , bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is related to: Broad Institute Genomics Platform
has parent organization: Broad Institute
has parent organization: Broad Institute of MIT and Harvard
Broad Institute Open source, Available to the biomedical community, The community can contribute to this resource biotools:gnomad https://github.com/macarthur-lab/gnomad_browser/issues, https://bio.tools/gnomad SCR_014964 SciCrunch Registry gnomAD 2.0, gnomAD Browser, gnomAD version 2.0, Exome Aggregation Consortium 2026-09-26 02:18:54 5310
lncRNAdb
 
Resource Report
Resource Website
100+ mentions
lncRNAdb (RRID:SCR_015491) data or information resource, database Searchable database of comprehensive annotations of eukaryotic long non-coding RNAs. Entries are manually curated from referenced literature. reference database, eukaryotic annotation, annotation database, eukaryotic long non coding rna database, functional long noncoding rnas, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
Open source, Acknowledgement requested, The community can contribute to this resource biotools:lncrnadb https://bio.tools/lncrnadb SCR_015491 SciCrunch Registry lncRNAdb v2.0, Long Noncoding RNA Database, Long Noncoding RNA Database v2.0 2026-09-26 02:18:54 165
UniCarbKB
 
Resource Report
Resource Website
10+ mentions
UniCarbKB (RRID:SCR_014410) data or information resource, database International effort which has created a glycomics knowledgebase with access to a database of information on the glycan structures of glycoproteins. It serves as and promotes an online information storage and search platform for glycomics and glycobiology research. Open access knowledgebase offers resource supported by querying interfaces, annotation technologies and the adoption of common standards to integrate structural, experimental and functional data. knowledgebase, glycomics, glycerin structure, glycoprotein, cell line, glycoproteomics knowledge platform, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Macquarie University; Sydney; Australia
has parent organization: University of Gothenburg; Gothenburg; Sweden
has parent organization: SIB Swiss Institute of Bioinformatics
is parent organization of: UniCarb-DB
DOI:10.1093/nar/gkt1128 Free, Freely available biotools:unicarbkb https://bio.tools/unicarbkb http://www.unicarbkb.org SCR_014410 SciCrunch Registry 2026-09-26 02:18:53 28
SnpSift
 
Resource Report
Resource Website
500+ mentions
SnpSift (RRID:SCR_015624) software resource, software toolkit, source code Software toolkit for filtering and manipulating annotated files. After annotation, the software's filter function can find relevant genomic variants in large data files. annotation, filtering, genomic variant, single nucleotide polymorphism, bio.tools is listed by: bio.tools
is listed by: Debian
works with: SnpEff
PMID:22728672 Open Source, Free, Available for download biotools:snpsift https://bio.tools/snpsift SCR_015624 SciCrunch Registry SnpEff 2026-09-26 02:18:55 631
ApiDB CryptoDB
 
Resource Report
Resource Website
10+ mentions
ApiDB CryptoDB (RRID:SCR_013455) ApiDB CryptoDB data or information resource, database An integrated genomic and functional genomic database for the parasite Cryptosporidium. CryptoDB integrates whole genome sequence and annotation along with experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining. Organisms included in CryptoDB are Cryptosporidium parvum, Cryptosporidium hominis, Cryptosporidium muris and environmental isolate sequences from numerous species. CryptoDB is allied with the databases PlasmoDB and ToxoDB via ApiDB, an NIH/NIAID-funded Bioinformatics Resource Center. Tools include: * BLAST: Identify Sequence Similarities * Sequence Retrieval: Retrieve Specific Sequences using IDs and coordinates * PubMed and Entrez: View the Latest Cryptosporidium Pubmed and Entrez Results * Genome Browser: View Sequences and Features in the genome browser * CryptoCyc: Explore Automatically Defined Metabolic Pathways * Searches via Web Services: Web service access to our data cryptosporidium parvum, cryptosporidium, cryptosporidium genome, cryptosporidium orf, cryptosporidium sage tag alignments, cryptosporidium snp, genomic sequence, dna motif, snp, est, orf, data set, bio.tools uses: SynView
is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
has parent organization: Eukaryotic Pathogen Database Resources
NIAID contract HHSN266200400037C PMID:16381902 nif-0000-02698, biotools:cryptodb, r3d100012265 https://bio.tools/cryptodb http://cryptodb.org/ SCR_013455 SciCrunch Registry CryptoDB, Cryptosporidium Genomics Resource 2026-09-26 02:18:51 26
Examl
 
Resource Report
Resource Website
50+ mentions
Examl (RRID:SCR_016087) Examl software application, software resource, source code Source code for large-scale phylogenetic analyses on whole-transcriptome and whole-genome alignments using supercomputers. phylogenetic, analysis, database, large scale, whole genome, whole transcriptome, alignment, efficiency, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
Heidelberg Institute for Theoretical Studies PMID:25819675 Free, Available for download OMICS_08024, biotools:ExaML https://bio.tools/ExaML, https://sources.debian.org/src/examl/ SCR_016087 SciCrunch Registry Examl:Exascale Maximum Likelihood 2026-09-26 02:18:55 62
ExPASy ABCD database
 
Resource Report
Resource Website
10+ mentions
ExPASy ABCD database (RRID:SCR_017401) ABCD ExPASy, The ABCD database data or information resource, database Repository of sequenced antibodies, integrating curated information about antibody and its antigen with cross links to standardized databases of chemical and protein entities. Manually curated repository of sequenced antibodies, developed by Geneva Antibody Facility at University of Geneva, in collaboration with CALIPHO and Swiss Prot groups at SIB Swiss Institute of Bioinformatics. Database provides list of sequenced antibodies with their known targets. Each antibody is assigned unique ID number that can be used in academic publications to increase reproducibility of experiments. Sequenced antibody, manually curated, known target, ExPASy, repository, chemically defined antibodies, antibody, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
is related to: SIB Swiss Institute of Bioinformatics
has parent organization: University of Geneva; Geneva; Switzerland
ProCare Foundation ;
Swiss National Science Foundation ;
University of Geneva
PMID:31410491 Free, Freely available SCR_019000, biotools:AbCD_database https://bio.tools/ABCD_database SCR_017401 SciCrunch Registry ExPASy ABCD (AntiBodies Chemically Defined) Database, The ABCD database, AntiBodies Chemically Defined, AntiBodies Chemically Defined Expert Protein Analysis System database, ExPASy ABCD Database, The AntiBodies Chemically Defined Database 2026-09-26 02:18:56 13
Signaling Pathways Project
 
Resource Report
Resource Website
10+ mentions
Signaling Pathways Project (RRID:SCR_018412) SPP data or information resource, database Web multi omics knowledgebase based upon public, manually curated transcriptomic and cistromic datasets involving genetic and small molecule manipulations of cellular receptors, enzymes and transcription factors. Integrated omics knowledgebase for mammalian cellular signaling pathways. Web browser interface was designed to accommodate numerous routine data mining strategies. Datasets are biocurated versions of publically archived datasets and are formatted according to recommendations of the FORCE11 Joint Declaration on Data Citation Principles73, and are made available under Creative Commons CC 3.0 BY license. Original datasets are available. Data integration, genetic database, gene regulatory network, cell signalling, cellular signalling network, transcriptomic data, manualy curated, cistromic data, cellular receptor, enzyme, transcrptomic factor, mammalian cellular signaling pathway, data mining strategy, dataset, , bio.tools is used by: Hypothesis Center
is listed by: Debian
is listed by: bio.tools
works with: Gene Expression Omnibus (GEO)
works with: NCBI Sequence Read Archive (SRA)
CPRIT RP150578;
Dan L. Duncan NCI Comprehensive Cancer Center at Baylor College of Medicine ;
NCI CA125123;
NHLBI HL127624;
NIDDK DK095686;
NIDDK DK097748;
NIDDK DK097771;
NIDDK DK105126;
NIDDK DK107535;
NIDDK DK48807;
NIDDK DK56338
PMID:31672983 Free, Freely available r3d100013650, biotools:Signaling_Pathways_Project https://bio.tools/Signaling_Pathways_Project, https://doi.org/10.17616/R31NJN0Y https://www.signalingpathways.org SCR_018412 SciCrunch Registry 2026-09-26 02:18:57 34
MethBase
 
Resource Report
Resource Website
1+ mentions
MethBase (RRID:SCR_017487) data or information resource, database, service resource Central reference methylome database created from public BS-seq datasets. Provides methylation level at individual sites, regions of allele specific methylation, hypo- or hyper-methylated regions, partially methylated regions, and detailed meta data and summary statistics. Methylome, database, public, BSseq, dataset, methylation, site, region, allele, specific, metadata, statistics, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Southern California; Los Angeles; USA
Free, Freely available BioTools:MethBase, biotools:Methbase https://bio.tools/MethBase, https://bio.tools/MethBase, https://bio.tools/MethBase SCR_017487 SciCrunch Registry MethBase: a reference methylome database 2026-09-26 02:18:56 1
VeryFastTree
 
Resource Report
Resource Website
1+ mentions
VeryFastTree (RRID:SCR_023594) software application, software resource, source code Software tool for speeding up estimation of phylogenetic trees for large alignments through parallelization and vectorization strategies. large alignments, phylogenetic tree, phylogenetic tree creation, bio.tools is listed by: bio.tools
is related to: FastTree
ERDF ;
MICINN ;
Xunta de Galicia
PMID:32573652
DOI:10.1093/bioinformatics/btaa582
Free, Available for download, Freely available biotools:veryfasttree https://bio.tools/veryfasttree SCR_023594 SciCrunch Registry 2026-09-26 02:18:59 8

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