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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
ggplot2
 
Resource Report
Resource Website
10000+ mentions
ggplot2 (RRID:SCR_014601) data processing software, data visualization software, software application, software resource Open source software package for statistical programming language R to create plots based on grammar of graphics. Used for data visualization to break up graphs into semantic components such as scales and layers. plotting system, r, graphics, data analysis, multi-layered graphics, bio.tools uses: ggpubr
uses: ggeffects
uses: ggsignif
is used by: riboWaltz
is used by: ClustVis
is used by: ggrepel
is used by: PlotsOfData
is used by: EnhancedVolcano
is used by: tidyverse
is used by: ComplexUpset
is used by: ggfortify
is used by: forestmodel
is used by: ggvenn
is used by: metaviz
is used by: ggVennDiagram
is used by: ggcyto
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
is related to: ggraph
is related to: ggbiplot
is related to: GGally
is related to: ggstatsplot
is related to: ggpointdensity
has parent organization: CRAN
works with: Plotly
works with: cowplot
works with: ggalluvial
works with: ggforce
works with: ggbreak
works with: ggrastr
works with: tidybayes
works with: ggsurvfit
works with: ggtext
works with: ggsci
Free, Freely available biotools:ggplot2 http://docs.ggplot2.org/current/, https://github.com/tidyverse/ggplot2, https://bio.tools/ggplot2 http://ggplot2.org/ SCR_014601 SciCrunch Registry grammar of graphics plot2 2026-09-28 09:33:16 42192
Metastats
 
Resource Report
Resource Website
100+ mentions
Metastats (RRID:SCR_014610) data analysis software, data processing software, software application, software resource, web application A statistical software package for comparing metagenomic datasets and clinical data sets comprised of two treatment populations, with each treatment population being made up of multiple samples. It relies on a non-parametric t-test. microbiome, statistics, software, metagenomics, clinical data, data analysis software, machine learning, web application, bio.tools is listed by: Human Microbiome Project
is listed by: bio.tools
is listed by: Debian
Open source, Acknowledgement requested biotools:metastats https://bio.tools/metastats SCR_014610 SciCrunch Registry 2026-09-26 02:15:27 390
OpenWorm
 
Resource Report
Resource Website
10+ mentions
OpenWorm (RRID:SCR_014650) simulation software, software application, software resource, web application 3D web browser that allows users to simulate and dissect virtual C. elegans. Users can explore the anatomy of a virtual, 3D worm by zooming in and out, rotating the model, and viewing the worm's different layers. NeuroML format and connector are used to enhance the simulation, and supporting programs and code are available for coders. simulation, model, web application, web browser, c elegans, nematode, worm, roundworm, open source, 3d, dissect, anatomy, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: WormBase
is hosted by: GitHub
PMID:25404913
DOI:10.3389/fncom.2014.00137
Open source, Code is available on GitHub, Available on the App Store SCR_014984, biotools:OpenWorm https://bio.tools/OpenWorm SCR_014650 SciCrunch Registry OpenWorm Browser, Open Worm 2026-09-26 02:15:28 21
FluoRender
 
Resource Report
Resource Website
100+ mentions
FluoRender (RRID:SCR_014303) data analysis software, data processing software, data visualization software, software application, software resource Interactive rendering tool for confocal microscopy data visualization. Combines rendering of multi-channel volume data and polygon mesh data, where properties of each dataset can be adjusted independently and quickly. Designed for neurobiologists, allowing them to better visualize confocal data from fluorescently-stained brains, but it is also useful for other biological samples. Features include feature tracking, 3D measurement tools, multiple render modes for multi-channel confocal data, and volume paint selection and segmentation. rendering tool, confocal microscopy data visualization, neurobiology, fluorescent stain, brain, bio.tools is used by: VVD Viewer
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Utah; Utah; USA
Free, Available for download, Freely available biotools:fluorender https://bio.tools/fluorender SCR_014303 SciCrunch Registry FluoRender Visualization 2026-09-26 02:15:24 130
NiftyFit
 
Resource Report
Resource Website
10+ mentions
NiftyFit (RRID:SCR_014301) software library, software resource, software toolkit Software package for multi-parametric model-fitting of 4D Magnetic Resonance Imaging data. Software library to facilitate voxel wise fitting on a number of datatypes including T1 and T2 relaxometry, Arterial Spin Labeled MRI, Diffusion Weighted Imaging and Dynamic Contrast Enhanced MRI. T software library, voxel wise fit, relaxometry, mri, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University College London; London; United Kingdom
EPSRC ;
MRC ;
NIHR BRC ;
NIHR
PMID:26972806 Free, Available for download, Freely available biotools:niftyfit, BioTools:niftyfit https://github.com/KCL-BMEIS/niftyreg, https://bio.tools/niftyfit, https://bio.tools/niftyfit, https://bio.tools/niftyfit SCR_014301 SciCrunch Registry 2026-09-26 02:15:24 14
ProtTest
 
Resource Report
Resource Website
1000+ mentions
ProtTest (RRID:SCR_014628) data analysis software, data processing software, software application, software resource, web application Web-based software used for the selection of best-fit models of protein evolution., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bioinformatics, model, best fit model, protein evolution, amino acid replacement, server, bio.tools uses: PhyML
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
is hosted by: GitHub
PMID:15647292
DOI:10.1093/bioinformatics/btr088
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_11547, biotools:prottest https://github.com/ddarriba/prottest3, https://bio.tools/prottest, https://sources.debian.org/src/prottest/ SCR_014628 SciCrunch Registry 2026-09-26 02:15:27 1984
FATCAT
 
Resource Report
Resource Website
100+ mentions
FATCAT (RRID:SCR_014631) software resource, web application Web server for flexible protein structure comparison. Structure alignment is formulated as the aligned fragment pairs chaining process allowing at most t twists, and the flexible structure alignment is transformed into a rigid structure alignment when t is forced to be 0., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. web server, protein, comparison, structure, flexible protein structure, protein structure comparison, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: FATCAT Flexible Structural Neighborhood
NIGMS GM101457;
NIGMS GM63208;
NIGMS GM076221;
NSF DBI-0349600
PMID:14534198 THIS RESOURCE IS NO LONGER IN SERVICE biotools:fatcat https://bio.tools/fatcat SCR_014631 SciCrunch Registry (Flexible structure AlignmenT by Chaining Aligned fragment pairs allowing Twists, (Flexible structure AlignmenT by Chaining Aligned fragment pairs allowing Twists (FATCAT) 2026-09-26 02:15:28 139
SortMeRNA
 
Resource Report
Resource Website
500+ mentions
SortMeRNA (RRID:SCR_014402) data analysis software, data processing software, sequence analysis software, software application, software resource Sequence analysis software for filtering, mapping and OTU-picking NGS reads. SortMeRNA takes as input a file of reads (fasta or fastq format) and one or multiple rRNA database file(s), and sorts apart rRNA and rejected reads into two files specified by the user., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence analysis software, filter, map, otu picking, ngs, sort, rna, rrna, bio.tools uses: QIIME
is listed by: Debian
is listed by: bio.tools
PMID:23071270
DOI:10.1093/bioinformatics/bts611
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02619, biotools:sortmerna https://bio.tools/sortmerna, https://sources.debian.org/src/sortmerna/ SCR_014402 SciCrunch Registry 2026-09-26 02:15:25 624
CummeRbund
 
Resource Report
Resource Website
100+ mentions
CummeRbund (RRID:SCR_014568) data analysis software, data processing software, sequence analysis software, software application, software resource Software R package used for simplifying and analyzing Cufflink RNA-Seq output. This program takes various output files from a cuffdiff run and creates a SQLite database of the results that will describe the appropriate relationships between the genes, transcripts, transcription start sites and CDS regions. r software, cufflink, rna-seq, sqlite, gene, transcript, transcription start site, cds region, r, rnaseq, rna seq, bio.tools, FASEB list uses: R Project for Statistical Computing
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
has parent organization: Harvard University; Cambridge; United States
Free, Freely available biotools:cummerbund, OMICS_07349 https://bio.tools/cummerbund, https://sources.debian.org/src/r-bioc-cummerbund/ SCR_014568 SciCrunch Registry 2026-09-26 02:15:27 366
FastQC
 
Resource Report
Resource Website
10000+ mentions
Rating or validation data
FastQC (RRID:SCR_014583) data analysis software, data management software, data processing software, software application, software resource Quality control software that perform checks on raw sequence data coming from high throughput sequencing pipelines. This software also provides a modular set of analyses which can give a quick impression of the quality of the data prior to further analysis. quality control, sequence data, sequencing, analysis, data quality, pipeline, raw sequence data, modular set, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
Open source, Available for download biotools:fastqc, SCR_005539, OMICS_01043 https://omictools.com/fastqc-tool, https://bio.tools/fastqc, https://sources.debian.org/src/fastqc/ SCR_014583 SciCrunch Registry FastQC v0.11.5 2026-09-26 02:15:27 19827
Mascot
 
Resource Report
Resource Website
5000+ mentions
Mascot (RRID:SCR_014322) data processing software, signal processing software, software application, software resource, standalone software A software package and server used to identify and characterize proteins from primary sequence databases using mass spectrometry data. Mascot integrates peptide mass fingerprinting, sequence querying, and MS/MS ion searching in order to search for proteins in databases like SwissProt, NCBInr, EMBL EST divisions, contaminants, and cRAP. If a license is purchased, users may: search data sets that exceed the 1200 spectrum limit of the free version; set up automated, high throughput work; add and edit proteins and quantification methods; and search a preferred collection of sequence databases. The software package works with instruments from AB Sciex, Agilent, Bruker, Jeol, Shimadzu, Thermo Scientific, and Waters. server, software package, mass spectrometry, protein, identify, characterize, bio.tools is used by: MSQuant
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MascotScan
Free, Can be licensed for in-house use, Available for download biotools:MASCOT http://www.matrixscience.com/search_intro.html, https://bio.tools/MASCOT SCR_014322 SciCrunch Registry Mascot Server 2026-09-26 02:15:24 7141
GROMACS
 
Resource Report
Resource Website
5000+ mentions
GROMACS (RRID:SCR_014565) simulation software, software application, software resource, software toolkit Software package created to perform molecular dynamics. Molecular dynamics package mainly designed for simulations of proteins, lipids, and nucleic acids. Can also be used for research on non-biological systems, such as polymers. simulation, molecular dynamics, software package, software toolkit, biochemical, molecule, protein, lipid, nucleic acid, bond interaction, bio.tools is used by: CHARMM-GUI
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
European Research Council ;
Nvidia ;
Stream Computing Performance Engineers ;
Swedish eScience Research Center ;
Swedish Foundation for International Cooperation in Research and Higher Education ;
Swedish Foundation for Strategic Research ;
Swedish National Infrastructure for Computing ;
Swedish Research Council
PMID:26620784
DOI:10.1016/0010-4655(95)00042-E
Free, Available for download biotools:gromacs, OMICS_05081 https://bio.tools/gromacs, https://sources.debian.org/src/gromacs/, https://github.com/gromacs/gromacs SCR_014565 SciCrunch Registry Gromacs 2026-09-26 02:15:27 9367
GEMINI
 
Resource Report
Resource Website
500+ mentions
GEMINI (RRID:SCR_014819) software resource Framework for exploring genetic variation in the context of the genome annotations available for the human genome. Users can load a VCF file into a database and each variant is automatically annotated by comparing it to several genome annotations from source such as ENCODE tracks, UCSC tracks, OMIM, dbSNP, KEGG, and HPRD. framework, genetic variation, annotation, human, genome, vcf, database, , bio.tools, FASEB list uses: KEGG
uses: ENCODE
uses: OMIM
uses: dbSNP
uses: HPRD - Human Protein Reference Database
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Utah; Utah; USA
DOI:10.1371/journal.pcbi.1003153 Freely available biotools:gemini https://github.com/arq5x/gemini, https://bio.tools/gemini SCR_014819 SciCrunch Registry GEnome MINIng (GEMINI), GEMINI - a flexible framework for exploring genome variation, Genome Mining, GEnome MINIng 2026-09-26 02:15:29 532
PAML
 
Resource Report
Resource Website
1000+ mentions
PAML (RRID:SCR_014932) PAML data analysis software, data processing software, software application, software resource, software toolkit Package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood. PAML estimates parameters and tests hypotheses to study the evolutionary process from a phylogenetic tree., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. phylogenetic analysis, dna, protein sequences, evolutionary process, estimate parameters, test hypothesis, maximum likelihood, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at Berkeley; Berkeley; USA
works with: PAUP
works with: PHYLIP
works with: PhyML
works with: RAxML
PMID:9367129
DOI:10.1093/molbev/msm088
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04238, biotools:paml https://bio.tools/paml, https://sources.debian.org/src/paml/ SCR_014932 SciCrunch Registry Phylogenetic Analysis by Maximum Likelihood, Phylogenetic Analysis by Maximum Likelihood (PAML) 2026-09-26 02:15:30 4962
CHiCAGO
 
Resource Report
Resource Website
100+ mentions
CHiCAGO (RRID:SCR_014941) data analysis software, data processing software, software application, software resource, software toolkit Statistical pipeline for detecting significant chromosomal interactions in Capture Hi-C data. CHiCAGO uses a convolution background model accounting for both random Brownian collisions between chromatin fragments and technical noise. CHiCAGO then performs a p-value weighting procedure based on the expected true positive rates at different distance ranges, with scores representing soft-thresholded -log weighted p-values., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. capture hi-c, capture hi-c data, chic, brownian collisions, chromatin, p-value weighting, genomic organization, genome, statistical analysis, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Babraham Institute
BBSRC ;
MRC UK ;
EMBL
PMID:27306882 THIS RESOURCE IS NO LONGER IN SERVICE biotools:chicago https://bitbucket.org/chicagoTeam/chicago, https://bio.tools/chicago SCR_014941 SciCrunch Registry Capture HiC Analysis of Genomic Organisation, Capture HiC Analysis of Genomic Organization, CHiCAGO: Capture HiC Analysis of Genomic Organisation 2026-09-26 02:15:30 163
SOAPnuke
 
Resource Report
Resource Website
1000+ mentions
SOAPnuke (RRID:SCR_015025) data analysis software, data processing software, sequence analysis software, software application, software resource Multi-threaded software for rapid quality control and preprocessing of high throughput sequencing data specified for different experiments. It consists of four modules that speed up the report on statistics graphs of raw datasets, preprocessed datasets and preprocessing status. sequence data, fastq, dge dataset, rna, metagenomics, bio.tools is listed by: SOAP
is listed by: bio.tools
is listed by: Debian
Open Source, Free biotools:soapnuke https://bio.tools/soapnuke SCR_015025 SciCrunch Registry 2026-09-26 02:15:31 1698
Bowtie 2
 
Resource Report
Resource Website
1000+ mentions
Bowtie 2 (RRID:SCR_016368) alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Ultrafast and memory efficient tool for aligning sequencing reads to long reference sequences. Supports gapped, local, and paired end alignment modes. More suited to finding longer, gapped alignments in comparison with original Bowtie method. sequence, analysis, long, reference, sequence, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools is used by: HLA-HD
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Bowtie
NHGRI R01 HG006102;
NIGMS R01 GM083873
PMID:22388286 Free, Available for download, Freely available biotools:bowtie2 http://bowtie-bio.sourceforge.net/bowtie2/index.shtml, https://github.com/BenLangmead/bowtie2, https://bio.tools/bowtie2 SCR_016368 SciCrunch Registry , bowtie 2, bowtie2 v 2.2.3 2026-09-26 02:15:28 1993
MetaMapR
 
Resource Report
Resource Website
1+ mentions
MetaMapR (RRID:SCR_014685) data processing software, data visualization software, software application, software resource An open-source software program for integrating enzymatic transformations with metabolite structural similarity, mass spectral similarity and empirical associations to generate connected metabolic networks and display results using data visualization techniques. metabolomics, metabolomics tool, enzymatic transformations, metabolite structural similarity, mass spectral similarity, metabolic networks, data visualization, bio.tools is listed by: Metabolomics Workbench
is listed by: Debian
is listed by: bio.tools
PMID:25847005 Open source biotools:metamapr https://bio.tools/metamapr SCR_014685 SciCrunch Registry 2026-09-26 02:15:28 9
GEN3VA
 
Resource Report
Resource Website
1+ mentions
GEN3VA (RRID:SCR_015682) data analysis software, data processing software, software application, software resource Software tool for aggregation and analysis of gene expression signatures from related studies.Used to aggregate and analyze gene expression signatures extracted from GEO by crowd using GEO2Enrichr. Used to view aggregated report that provides global, interactive views, including enrichment analyses, for collections of signatures from multiple studies sharing biological theme. GEO2Enrichr, gene expression signatures, enrichment analyses, multiple studies, biological theme, bio.tools is listed by: bio.tools
is listed by: Debian
works with: Gene Expression Omnibus (GEO)
NCI U54 CA189201;
NHLBI U54 HL127624;
NIGMS R01 GM098316
PMID:27846806 Free, Freely available biotools:gen3va https://github.com/MaayanLab/gen3va, https://bio.tools/gen3va SCR_015682 SciCrunch Registry GENE Expression and Enrichment Vector Analyzer 2026-09-26 02:15:35 5
Off-Spotter
 
Resource Report
Resource Website
50+ mentions
Off-Spotter (RRID:SCR_015739) algorithm resource, software resource, web application Web application that identifies genomic instances for a given combination of gRNA(s), PAM, number of mismatches, and seed. This tool is limited to a single 1,000 nucleotides sequence or fewer than twenty CR-separated 20-mers. CRISPR, Cas, sgrna, prokaryotic immune system, genetic engineering, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Thomas Jefferson University; Pennsylvania; USA
William M. Keck Foundation PMID:25630343 Freely available, Free, Available for download, Tutorial available biotools:off-spotter https://bio.tools/off-spotter SCR_015739 SciCrunch Registry Off-Spotter: tool for CRISPR/Cas design, Off-spotter sgRNA algorithm 2026-09-26 02:15:36 53

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