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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.psbc.org/home/index.htm
At Puget Sound Blood Center, when we talk about the work of our Research Institute, what we are really talking about is saving lives. Many recognize the lifesaving work of the Blood Center for its role in maintaining the blood supply for Western Washington. But that is only the beginning of how the Blood Center touches the lives of people all over the world. The Blood Center is widely considered the premier knowledge source on blood research and transfusion medicine and has been developing cutting-edge technologies and establishing best practices in this field for over sixty-six years. Medical institutions worldwide rely on the Blood Center''s research work. Scientific equipment manufacturers, as well as pharmaceutical companies turn to the Blood Center for help in developing effective equipment and successful therapies that are saving lives around the world every day.
Proper citation: Puget Sound Blood Center (RRID:SCR_010527) Copy
Brain bank that harvests, banks and disperses postmortem tissue for use in brain and medical research. It also provides neuropathologic diagnoses of organic dementia in a cohort of NIH sponsored research subjects. The bank includes tissue primarily from patients with Alzheimer's but also includes Huntington's, Parkinson's, and other disorders.
Proper citation: Oregon Brain Bank (RRID:SCR_013085) Copy
http://www.psoriasis.org/netcommunity/act_biobank
The National Psoriasis Victor Henschel BioBank is a collection of biological samples and clinical information used by qualified scientists to further the field of psoriasis genetics. Once completed, the National Psoriasis BioBank will be the largest collection of psoriasis DNA samples in the world, moving us closer to understanding the causes of psoriatic diseases, discovering more and better treatments and finding a cure. The BioBank is currently collecting DNA from people with and without psoriasis and/or psoriatic arthritis. Simply by donating your DNA����??a blood sample and a swab of your cheek cells����??and providing us with your medical history, you can help us find a cure. Samples will be processed and stored at a private laboratory and not at the National Psoriasis Foundation. The National Psoriasis BioBank is part of the Genetic Alliance BioBank (GA BioBank), a centralized repository for the collection, storage and distribution of biological samples (including DNA, serum, cells and tissues) and clinical data for genetic researchers.
Proper citation: National Psoriasis BioBank (RRID:SCR_010537) Copy
http://www.eurobiobank.org/en/partners/description/inncb_copy.htm#organisation
A biobank of human biological material and genetic information. It provides samples and information to researchers in order to identify new genes and clarify pathogenic mechanisms of diseases. The biobank offers biochemical and molecular diagnoses of genetic dystonias, Parkinson's disease and NBIA disorders, as well as storage of biological samples for external institutions.
Proper citation: Movement Disorders Biobank (RRID:SCR_010659) Copy
http://brainhealthregistry.org/
A website aimed at recruiting and assessing subjects for all types of neuroscience studies with the internet. The hope is to accelerate various types of observational studies and clinical trials, and also reduce costs. They are interested in having people, including healthy subjects of all ages, join the registry. Joining only takes a few minutes. The web-based project is designed to speed up cures for Alzheimer's, Parkinson's and other brain disorders. It uses online questionnaires and online neuropsychological tests (which are very much like online brain games).
Proper citation: Brain Health Registry (RRID:SCR_010230) Copy
http://cihd.cores.utah.edu/mgd/
Core facility which provides custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of interest. It also provides hardware, reagents, and expertise for optimizing and performing HRMA for genes of interest.
Proper citation: Center for Iron and Heme Disorders at the University of Utah Mutation Generation and Detection Core (RRID:SCR_015339) Copy
http://www.cancer.iu.edu/research-trials/facilities/angiobiocore/index.shtml
Core facility which conducts validated and reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology Angiogenesis Core (RRID:SCR_015345) Copy
http://medicine.yale.edu/labmed/ycceh/cores/core_d/index.aspx
Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice.
Proper citation: Yale Cooperative Center of Excellence in Hematology Animal Modeling Core (RRID:SCR_015349) Copy
http://zfrhmaps.tch.harvard.edu/cemh/CoreC.htm
Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis.
Proper citation: Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core (RRID:SCR_015352) Copy
http://www.kidneycenter.pitt.edu/cores/imaging_core.html
Core that provides qualitative and quantitative image analysis of the kidney and lower urinary tract through performing light and electron microscopic analysis of epithelial cells and tissues, quantifying and reconstructing kidney and lower urinary tract-associated tissues and organs in 3D, and visualizing and quantifying molecular and cellular dynamics in living animals.
Proper citation: Pittsburgh Center for Kidney Research Kidney Imaging (RRID:SCR_015289) Copy
https://www.uab.edu/medicine/obriencenter/cores/clinical-studies-of-aki-core
Core facility which provides investigators access to patients with AKI through an established international network of collaborating investigators. It also provides core resources to support the design and conduct of clinical research in AKI and genomics resources to perform systematic genomic analyses and allow correlation with clinical phenotypic information.
Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Clinical Studies of AKI (RRID:SCR_015287) Copy
http://www.kidneycenter.pitt.edu/cores/cell_physiology.html
Core that provides investigators with in vitro systems for the study of transport processes at the molecular, cell, and epithelial levels.
Proper citation: Pittsburgh Center for Kidney Research Cellular Physiology (RRID:SCR_015284) Copy
http://www.kidneycenter.pitt.edu/cores/single_nephron_core.html
Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest.
Proper citation: Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285) Copy
https://www.uab.edu/medicine/obriencenter/cores/biostatistics-core
Core provides statistical expertise in the conceptualization and design of projects, expertise in data management for the resulting clinical and bioinformatics data, and assistance with the preparation of project reports, presentations and manuscripts.
Proper citation: University of Alabama at Birmingham-University of California San Diego O'Brien Center for Acute Kidney Injury Research Biostatistical Core (RRID:SCR_015283) Copy
http://sharedresources.fredhutch.org/core-facilities/genomics
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides expertise and support for generating genomics-based data. Services for DNA arrays, genetic analysis, and high-throughput screening are provided through three specialized laboratories.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Genomics Shared Resource (RRID:SCR_015327) Copy
http://obriencenter.yale.edu/humangenetics.aspx
Core that provides infrastructure support for several key steps in translational research, including development of HIC protocols, patient recruitment, patient DNA extraction and archiving, tools for high throughput SNP genotyping and DNA sequencing, and analysis of genetic linkage and linkage disequilibrium.
Proper citation: George M. O'Brien Kidney Center at Yale Human Genetics and Clinical Research Core (RRID:SCR_015298) Copy
http://cihd.cores.utah.edu/ironheme/
Core facility that provides analysis of metals, precursor porphyrins and heme for cell pellets, tissue, whole blood, urine, feces and other complex biological materials. It also provides measurements of activity of the enzymes responsible for heme biosynthesis for cell pellets, tissue and blood.
Proper citation: Center for Iron and Heme Disorders at the University of Utah Iron and Heme Core (RRID:SCR_015336) Copy
Core whose aim is to translate basic science research into effective diagnostic and therapeutic strategies that will improve the lives of patients by interrupting the pathogenesis of chronic kidney disease and its attendant high risk of cardiovascular disability and death. It combines comprehensive human genetics with phenotyping of subjects.
Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Clinical and Translational Core (RRID:SCR_015295) Copy
https://www.cincinnatichildrens.org/research/divisions/n/nephrology/biomarker-lab
Core whose goals are to provide high throughput Clinical Biofluid Profiling Services (including initial web-based and in-person consultation, study design, sample preparation and processing, data acquisition, data analysis, protein purification, target identification, and specific assay development and validation) and services pertaining to Biomarker measurement and validation (including design of ELISA and Western Blots, measurement of known and emerging markers of acute and chronic kidney diseases, as well as consultation for biomarker statistics and clinical trials design).
Proper citation: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center Biomarker Core (RRID:SCR_015300) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/histology-core
Core that provides light microscopy services like prosection, tissue fixation, processing, embedding, sectioning, staining and cover slipping of paraffin, frozen and soft plastic tissue sections, as well as specialized and routine fixation, tissues processing, ultramicrotomy, staining, photomicrograph production, and analysis.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Histology Core (RRID:SCR_015385) Copy
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