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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core is outgrowth of Michigan-UNC Peer Support Core, funded through Michigan Center for Diabetes Translational Research, 2016-21. It continues the Peer Support Core’s emphasis on the variety of peers and peer support approaches and the processes that undergird them, while expanding on these to include families and communities. Services include individual consultation to researchers and on research projects, national outreach, and facilitation such as through webinars and annual research workshops of national Special Interest Group of researchers interested in contributions of and interactions among community, peer, and family supports for reducing inequity in diabetes prevention and management.
Proper citation: Michigan Center for Diabetes Translational Research Leveraging Community, Peer, and Family Support Core Facility (RRID:SCR_015169) Copy
http://diabetesresearchcenter.dom.wustl.edu/translational-diagnostics-core/
Core provides range of assays for human and animal hormones, peptides, and metabolites related to metabolic disorders.
Proper citation: Washington University School of Medicine Diabetes Research Center Translational Diagnostics Core (RRID:SCR_015161) Copy
http://chicagodiabetesresearch.org/cores/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provides analytic support for a wide range of projects in diabetes translation research ranging from program evaluation to cost-effectiveness analysis.
Proper citation: Chicago Center for Diabetes Translation Research Quantitative Analysis Core (RRID:SCR_015208) Copy
http://cure.med.ucla.edu/cores/morphology-and-imaging
Core facility which provides services through centralized resources and facilities, as well as training and assistance for the application of morphological, imaging and stem cell biology technologies and promoting collaborations among CURE:DDRCC investigators with independently-funded research projects.
Proper citation: CURE - Digestive Diseases Research Center Morphology and Imaging Core (RRID:SCR_015209) Copy
http://www.cure.med.ucla.edu/cores/human-studies
Core facility whose services include secretory tests, motility and pH tests, videoendoscopy, biopsy and histology, serum bank of patients with ulcer hemorrhage, and visceral sensitivity and autonomic function tests.
Proper citation: CURE - Digestive Diseases Research Center Human Studies Core (RRID:SCR_015207) Copy
http://www.einstein.yu.edu/centers/diabetes-translational-research/lcmc/
Core facility that supports type II translational research in diabetes prevention and control. The life course perspective focuses on biopsychosocial and behavioral processes that individuals experience during particular periods in their life, and examines the interplay between these exposures in shaping disease risk.
Proper citation: New York Regional Center for Diabetes Translation Research Life Course Methodology Core (RRID:SCR_015176) Copy
https://case.edu/medicine/cddrcc/cores/
Collection of four cores: the biorepository core, for clinical specimen storage; the Histology/Imaging Core, for tissue preparation and sectioning; the Mouse Models Core, for education and training on various mouse modeling techniques; and the Clinical Component of the Administrative Core, for clinical study design consultation.
Proper citation: Cleveland Digestive Diseases Research Core Facilities (RRID:SCR_015216) Copy
http://www.med.upenn.edu/idom/drc/cores/ria.html
Core which offers high quality immunoassay services to basic, translational, and clinical investigators performing diabetes and related metabolic disease research. The core also provides consultation and training and education services.
Proper citation: Penn Diabetes Research Center Radioimmunoassay and Biomarkers Core Facility (RRID:SCR_010028) Copy
https://labnodes.vanderbilt.edu/community/profile/id/2230
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that supports diabetes, endocrine, and metabolic research across a range of species. Its objective is to provide sensitive, reproducible, and inexpensive analyses of hormones, amino acids, and other relevant chemicals.
Proper citation: Vanderbilt Diabetes Research and Training Center Hormone Assay and Analytical Services Core Facility (RRID:SCR_010181) Copy
https://labnodes.vanderbilt.edu/community/profile/id/2229
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides any Vanderbilt researcher with access to imaging equipment and expert technical support for microscopy and analysis of tissue and cellular physiology.
Proper citation: Vanderbilt Diabetes Research and Training Center Cell Imaging Shared Resource Core Facility (RRID:SCR_010165) Copy
http://fcon_1000.projects.nitrc.org/indi/pro/nyu.html
Datasets including a collection of scans from 49 psychiatrically evaluated neurotypical adults, ranging in age from 6 to 55 years old, with age, gender and intelligence quotient (IQ) information provided. Future releases will include more comprehensive phenotypic information, and child and adolescent datasets, as well as individuals from clinical populations. The following data are released for every participant: * At least one 6-minute resting state fMRI scan (R-fMRI) * * One high-resolution T1-weighted mprage, defaced to protect patient confidentiality * Two 64-direction diffusion tensor imaging scans * Demographic information (age, gender) and IQ-measures (Verbal, Performance, and Composite; Weschler Abbreviated Scale of Intelligence - WASI) * Most participants have 2 R-fMRI scans, collected less than 1 hour apart in the same scanning session. Rest_1 is always collected first.
Proper citation: NYU Institute for Pediatric Neuroscience Sample (RRID:SCR_010458) Copy
http://fcon_1000.projects.nitrc.org/indi/pro/VirginiaTech.html
Dataset including a T1 weighted anatomical image as well as two 10-minute resting state scans acquired during the same session from 25 psychiatrically screened healthy adults (community sample) ranging in age from 18 to 65 years old, with age, sex, education level, and ethnicity provided. Some subjects also returned several weeks after the first scan for a second scanning session. The number of days between scan sessions, for subjects that had two sessions, is indicated in the demographics spreadsheet. The study scanning protocol included: # 13 sec localizer # 4 minute 38 second T1 weighted anatomical # Subject given instructions for resting state scan #1 # 10 minute 4 second resting state scan #1 # Subject given instructions for resting state scan #2 # 10 minute 4 second resting state scan #2 Scanning was performed on one of three different 3T Siemens TIM TRIOs at the Human Neuroimaging Lab at Baylor College of Medicine in Houston, Texas. All scans were acquired using the standard Siemen''s TIM 12-channel head matrix. The resting state scans were acquired with a custom sequence that is a slight modification to the standard Siemen''s EPI sequence that supports real-time fMRI. Images were acquired slightly oblique to minimize dephasing in the orbito-frontal cortex. Detailed scanning parameters are included in separate .pdf files.
Proper citation: Virginia Tech Carilion Research Institute Sample (RRID:SCR_010459) Copy
http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/6219
A public-use microdata sample focusing on the older population created from the 1990 census. This sample consists of 3 percent of households with at least one member aged 60 or older. Although, the highest age presented is age 90, this allows analysis of data on the very old for most states with a reasonable degree of reliability. Since data for all members in households containing a person 60 years and over will be on the file, users will be able to analyze patterns such as living arrangements and sources of household income from which older members may benefit. Additionally, users will be able to augment the PUMS-O sample with a PUMS file. The Census Bureau has issued two regular PUMS files for the entire population. One PUMS file will contain 1 percent of all households; the other PUMS file will contain 5 percent of all households. Both files have most sample data items, and differ only in geographical composition. The 1-percent file contains geographic areas that reflect metropolitan vs. non-metropolitan areas. The 5-percent file shows counties or groups of counties as well as large sub-county areas such as places of 100,000 or more. The geography on the 5-percent PUMS file matches that of the PUMS-O file. Since data for different households are present on the two files, users can merge the PUMS-O file with the 5-percent PUMS to construct an 8-percent sample. However, weighted averages must be constructed for any estimates created because each sample yields state-level estimates. Thus, it is possible to analyze substate areas even for the very old. In states where the geographic areas identified on the PUMS-O and the 5-percent PUMS are coterminous with State Planning and Service Areas (used by service providers in relation to the Older Americans Act), the Planning and Service Areas are identified. * Dates of Study: 1990-2000 Links: 1980: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/08101 2000: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/04204
Proper citation: Public Use Microdata Sample for the Older Population (RRID:SCR_010487) Copy
Whole genome sequencing data for 454 unrelated Scripps Wellderly Study participants with European ancestry from a project that is studying the genetic architecture of exceptional healthspan from a cohort comprised of more than 1300 healthy individuals over the age of 80 years. SWGR_v1.0 includes chromosome-specific VCF4.1 bgzipped and tabix indexed files. Annotations for each variant can be found at Scripps Genome ADVISER (SG-ADVISER, http://genomics.scripps.edu/) Additional data releases are expected.
Proper citation: Scripps Wellderly Genome Reference (RRID:SCR_010250) Copy
http://fcon_1000.projects.nitrc.org/indi/retro/cobre.html
Data set of raw anatomical and functional MR data from 72 patients with Schizophrenia and 75 healthy controls (ages ranging from 18 to 65 in each group). All subjects were screened and excluded if they had: history of neurological disorder, history of mental retardation, history of severe head trauma with more than 5 minutes loss of consciousness, history of substance abuse or dependence within the last 12 months. Diagnostic information was collected using the Structured Clinical Interview used for DSM Disorders (SCID). A multi-echo MPRAGE (MEMPR) sequence was used with the following parameters: TR/TE/TI = 2530/(1.64, 3.5, 5.36, 7.22, 9.08)/900 ms, flip angle = 7��, FOV = 256x256 mm, Slab thickness = 176 mm, Matrix = 256x256x176, Voxel size =1x1x1 mm, Number of echos = 5, Pixel bandwidth =650 Hz, Total scan time = 6 min. With 5 echoes, the TR, TI and time to encode partitions for the MEMPR are similar to that of a conventional MPRAGE, resulting in similar GM/WM/CSF contrast. Rest data was collected with single-shot full k-space echo-planar imaging (EPI) with ramp sampling correction using the intercomissural line (AC-PC) as a reference (TR: 2 s, TE: 29 ms, matrix size: 64x64, 32 slices, voxel size: 3x3x4 mm3). Slice Acquisition Order: Rest scan - collected in the Axial plane - series ascending - multi slice mode - interleaved MPRAGE - collected in the Sag plane - series interleaved - multi slice mode - single shot The following data are released for every participant: * Resting fMRI * Anatomical MRI * Phenotypic data for every participant including: gender, age, handedness and diagnostic information.
Proper citation: COBRE (RRID:SCR_010482) Copy
Data set of annual questionnaires of a long-term prospective study of 1,337 former Johns Hopkins University medical students to identify precursors of premature cardiovascular disease and hypertension. The purpose of the study has broadened, however, as the cohort has aged. The study has been funded for 15 years. Participants were an average of 22 years of age at entry and have been followed to an average age of 69 years. Data are collected through annual questionnaires, supplemented with phone calls and substudies. Self-reports of diseases and risk factors have been validated. Every year from 1988 to 2003, anywhere from 2 to 6 questionnaires have been administered, in categories such as the following, which repeat periodically: Morbidity, Supplemental Illness, Health Behavior, Family and Career, Retirement, Job Satisfaction, Blood Pressure and Weight, Medications, Work Environment, Social Network, Diabetes, Osteoarthritis, Health Locus of Control, Preventive Health Services, General Health, Functional Limitations, Memory Functioning, Smoking, Religious Beliefs and Practices, Links with Administrative Data, National Death Index searches for all nonrespondents * Dates of Study: 1946-2003 * Study Features: Longitudinal * Sample Size: 1,337 (1946)
Proper citation: Precursors of Premature Disease and Death (RRID:SCR_010483) Copy
Core whose services include consultation in the choice of genomics methodologies to be applied to research problems being addressed by Digestive Diseases Center members, training in the conduct of functional genomics and metagenomics relevant to GI research, providing mammalian gene expression, cytokine/transcription factor/signaling pathway arrays, and gut microbial profiling/metagenomics to DDC members at discounted prices, and conducting periodic workshops and disseminating information about new technologies available in the Core and to obtain feedback on needed technologies / services.
Proper citation: Texas Medical Center Digestive Diseases Center Functional Genomics and Microbiome (RRID:SCR_015214) Copy
http://diabetesresearch.med.umich.edu/Core_MCDTR_Intervention.php
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that provides assistance to the Michigan Center for Diabetes Translational Research. Its three main services are consultation on content development and technologies, consultation about evidence for translatable diabetes interventions, and providing access to patient-centered health platforms.
Proper citation: Michigan Center for Diabetes Translational Research Intervention and Technology Research Core (RRID:SCR_015170) Copy
http://diabetesresearchcenter.dom.wustl.edu/immunology-of-type-1-diabetes-core/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core facility that provides logistic support to investigators examining autoimmune or type 1 diabetes mellitus (T1DM) or other endocrine autoimmunities. Its main purpose is to foster fundamental studies on T1DM through support for acquisition and use of diabetogenic strains of mice, islet isolation, and distribution of cells and antibodies relevant for immunological studies of T1DM.
Proper citation: Washington University School of Medicine Diabetes Research Center Immunology of Type 1 Diabetes Core (RRID:SCR_015143) Copy
https://digestivediseasescenters.org/content/ddrc-uab-molecular-pathology-and-human-celltissue-core
Core that provides both morphological analysis of mucosal tissues and instructs investigators in the techniques used to prepare tissue sections and analyze the morphology and cellular components of the mucosa and primary human gut (intestinal and rectal) cells, gastric mononuclear cells and genital (cervical and vaginal) cells and instruction on how to construct mucosal tissue explants in a transwell chamber system.
Proper citation: Mucosal HIV and Immunobiology Center Molecular Pathology and Human Cell and Tissue Core (RRID:SCR_015265) Copy
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