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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
National institute that is the largest scientific organization in the world dedicated to research focused on the understanding, treatment, and prevention of mental disorders and the promotion of mental health. NIMH envisions a world in which mental illnesses are prevented and cured. The mission of NIMH is to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery and cure. For the Institute to continue fulfilling this vital public health mission, it must foster innovative thinking and ensure that a full array of novel scientific perspectives are used to further discovery in the evolving science of brain, behavior, and experience. In this way, breakthroughs in science can become breakthroughs for all people with mental illnesses. In support of this mission, NIMH will generate research and promote research training to fulfill the following four objectives: * Promote discovery in the brain and behavioral sciences to fuel research on the causes of mental disorders * Chart mental illness trajectories to determine when, where, and how to intervene * Develop new and better interventions that incorporate the diverse needs and circumstances of people with mental illnesses * Strengthen the public health impact of NIMH-supported research To reach these goals, the NIMH divisions and programs are designed to emphasize translational research spanning bench, to bedside, to practice. For targeted priorities and funding initiatives, please visit our division websites
Proper citation: National Institute of Mental Health (RRID:SCR_011431) Copy
http://clinicalcenter.nih.gov/
The NIH Clinical Center is the nation's largest hospital devoted entirely to clinical research. Clinician-investigators translate scientific observations and laboratory discoveries into new approaches to diagnosing, treating, and preventing disease. The Clinical Center was recognized with the 2011 Lasker~Bloomberg Public Service Award for serving as a model research hospital—providing innovative therapy and high-quality patient care, treating rare and severe diseases, and producing outstanding clinician-scientists whose collective work has set a standard of excellence in biomedical research. About 1,500 clinical research studies are in progress at the Clinical Center. Half are studies of the natural pathogenesis of disease, especially rare diseases, which often are not studied anywhere else. What researchers learn by studying rare diseases adds to the basic understanding of common diseases. Most other studies are clinical trials, the first tests of new drugs and therapies in people. The clinical trials at the Clinical Center are predominantly Phase I and Phase II—first-in-human to test safety and efficacy. Clinical and laboratory research is conducted shoulder-to-shoulder, and this tandem approach drives all aspects of the Clinical Center's operations. More than 400,000 research volunteers have participated in clinical research studies at the Clinical Center since the hospital opened in 1953. Each year, the center sees 10,000 new research participants, of which there are two types: patient volunteers and healthy volunteers. Patient volunteers are people with specific diseases or conditions who help medical investigators learn more about their condition or test new medications, procedures, or treatments. A healthy volunteer is a person with no known significant health problems who plays a vital role in research to test a new drug, device, or intervention. At the Clinical Center, clinical research participants are active partners in medical discovery, a partnership that has resulted in a long list of medical milestones, including the first cure of a solid tumor with chemotherapy, gene therapy, use of AZT to treat AIDS, and successful replacement of a mitral valve.
Proper citation: NIH Clinical Center (RRID:SCR_011464) Copy
The National Institute on Minority Health and Health Disparities (NIMHD) leads scientific research to improve minority health and eliminate health disparities. To achieve its mission, the NIMHD: * Plans, reviews, coordinates, and evaluates all minority health and health disparities research and activities of the NIH; * Conducts and supports research on health disparities; * Promotes and supports the training of a diverse research workforce; * Translates and disseminates research information; and * Fosters innovative collaborations and partnerships. The NIMHD envisions an America in which all populations will have an equal opportunity to live long, healthy and productive lives.
Proper citation: National Institute on Minority Health and Health Disparities (RRID:SCR_011441) Copy
NLM collects, organizes, and makes available biomedical science information to scientists, health professionals, and the public. The Library's Web-based databases, including PubMed/Medline and MedlinePlus, are used extensively around the world. NLM conducts and supports research in biomedical communications; creates information resources for molecular biology, biotechnology, toxicology, and environmental health; and provides grant and contract support for training, medical library resources, and biomedical informatics and communications research. Celebrating its 175th anniversary in 2011, the National Library of Medicine (NLM), in Bethesda, Maryland, is a part of the National Institutes of Health, U.S. Department of Health and Human Services (HHS). Since its founding in 1836 as the library of the U.S. Army Surgeon General, NLM has played a pivotal role in translating biomedical research into practice. It is the world's largest biomedical library and the developer of electronic information services that deliver trillions of bytes of data to millions of users every day. Scientists, health professionals, and the public in the United States and around the globe search the Library's online information resources more than 1 billion times each year. The Library is open to all and has many services and resources for scientists, health professionals, historians, and the general public. NLM has over 17 million books, journals, manuscripts, audiovisuals, and other forms of medical information on its shelves, making it the largest health-science library in the world. In today's increasingly digital world, NLM carries out its mission of enabling biomedical research, supporting health care and public health, and promoting healthy behavior by: * Acquiring, organizing, and preserving the world's scholarly biomedical literature; * Providing access to biomedical and health information across the country in partnership with the 5,800-member National Network of Libraries of Medicine (NN/LM); * Serving as a leading global resource for building, curating and providing sophisticated access to molecular biology and genomic information, including those from the Human Genome Project and NIH Common Fund; * Creating high-quality information services relevant to toxicology and environmental health, health services research, and public health; * Conducting research and development on biomedical communications systems, methods, technologies, and networks and information dissemination and utilization among health professionals, patients, and the general public; * Funding advanced biomedical informatics research and serving as the primary supporter of pre- and post-doctoral research training in biomedical informatics at 18 U.S. universities.
Proper citation: National Library of Medicine (RRID:SCR_011446) Copy
http://orf.od.nih.gov/Construction/Funding/
http://orf.od.nih.gov/Construction/Funding/
Proper citation: Office of research facilities development and operations (RRID:SCR_012864) Copy
The National Institutes of Health (NIH) has established a new center, called the National Center for Advancing Translational Sciences (NCATS). Currently, many costly, time-consuming bottlenecks exist in the translational pipeline. Working in partnership with the public and private sectors, the Center will develop innovative ways to reduce, remove or bypass these bottlenecks. This will speed the delivery of new drugs, diagnostics and medical devices to patients. The mission of the National Center for Advancing Translational Sciences is to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. NCATS is formed primarily by uniting and realigning existing NIH programs that play key roles in translational science. The Center will not be a drug development company, but will focus on using science to create powerful new tools and technologies that can be adopted widely by translational researchers in all sectors.
Proper citation: National Center for Advancing Translational Sciences (RRID:SCR_012857) Copy
http://aidsinfo.nih.gov/DrugsNew/Default.aspx?MenuItem=Drugs
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 12,2025. The AIDSinfo Drug Database provides fact sheets on HIV/AIDS related drugs. The fact sheets describe the drug''s use, pharmacology, side effects, and other information. The database includes: -Approved and investigational HIV/AIDS related drugs -Three versions of each fact sheet: patient, health professional, and Spanish. AIDSinfo is a 100% federally funded U.S. Department of Health and Human Services (DHHS) project that offers the latest federally approved information on HIV/AIDS clinical research, treatment and prevention, and medical practice guidelines for people living with HIV/AIDS, their families and friends, health care providers, scientists, and researchers. Sponsors: -National Institutes of Health (NIH) Office of AIDS Research National Institute of Allergy and Infectious Diseases (NIAID) National Library of Medicine (NLM) -Health Resources and Services Administration (HRSA) -Centers for Disease Control and Prevention (CDC) -Centers for Medicare and Medicaid Services (CMS)
Proper citation: AIDSinfo Drug Database (RRID:SCR_012899) Copy
http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml
This resource gives information about the U.S. Human Genome Project, which was was a 13-year effort to to discover all the estimated 20,000-25,000 human genes and make them accessible for further biological study. The primary project goals were to: - identify all the approximately 20,000-25,000 genes in human DNA, - determine the sequences of the 3 billion chemical base pairs that make up human DNA, - store this information in databases, - improve tools for data analysis, - transfer related technologies to the private sector, and - address the ethical, legal, and social issues (ELSI) that may arise from the project. To help achieve these goals, researchers also studied the genetic makeup of several nonhuman organisms. These include the common human gut bacterium Escherichia coli, the fruit fly, and the laboratory mouse. These parallel studies helped to develop technology and interpret human gene function. Sponsors: The DOE Human Genome Program and the NIH National Human Genome Research Institute (NHGRI) together sponsored the U.S. Human Genome Project.
Proper citation: Human Genome Project Information (RRID:SCR_013028) Copy
http://public.csr.nih.gov/Pages/default.aspx
The Center for Scientific Review (CSR) is the portal for NIH grant applications and their review for scientific merit. We receive all research grant applications sent to NIH and handle the review of more than 70% of those by organizing peer review groups (study sections) to evaluate research grant applications. Our mission is to see that NIH grant applications receive fair, independent, expert, and timely reviews — free from inappropriate influences — so NIH can fund the most promising research. The Center specifically: * Serves as the central receipt point for all research and training grant applications submitted to NIH. Also receives some of the applications submitted to other components of the U.S. Department of Health and Human Services (HHS) and refers them to these components; * Assigns all NIH applications to the appropriate NIH institutes or centers for consideration for funding and also to the scientific review groups within CSR or other institutes or centers for review; * Provides the scientific merit review of most research grant and fellowship applications submitted to NIH; * Provides staff support to the Office of the Director, NIH, in the formulation of grant and award policies and procedures; and * Assists other NIH components in providing information on the NIH peer review system and information about the research grant and fellowship application process and procedures to the scientific community, Congress, other NIH staff, and the general public.
Proper citation: Center for Scientific Review (RRID:SCR_013211) Copy
National institute whose mission is to reduce the burden of neurological disease - a burden borne by every age group, by every segment of society, by people all over the world. To accomplish this goal the NINDS supports and conducts basic, translational, and clinical research on the normal and diseased nervous system. The Institute also fosters the training of investigators in the basic and clinical neurosciences, and seeks better understanding, diagnosis, treatment, and prevention of neurological disorders. NINDS: * Conducts, fosters, coordinates, and guides research on the causes, prevention, diagnosis, and treatment of neurological disorders and stroke, and supports basic research in related scientific areas. * Provides grants-in-aid to public and private institutions and individuals in fields related to its areas of interest, including research project, program project, and research center grants. * Operates a program of contracts for the funding of research and research support efforts in selected areas of institute need. * Provides individual and institutional fellowships to increase scientific expertise in neurological fields. * Conducts a diversified program of intramural and collaborative research in its own laboratories, branches, and clinics. * Collects and disseminates research information related to neurological disorders.
Proper citation: National Institute of Neurological Disorders and Stroke (RRID:SCR_013116) Copy
A software resource application which organizes research literature. Users can import PDF articles into the application and create a searchable library. ReadCube enables users to perform keyword searches and provides references as well as note-taking tools. ReadCube also recommends articles to users based on library contents. For publishers, ReadCube enables interactive PDF versions of articles with tools for readers to make notes or perform author and keyword searches.
Proper citation: ReadCube (RRID:SCR_013777) Copy
A web application which finds new and relevant scientific literature based on keyword searches and filters. Users can also share, organize, and collaborate on papers using tools within Scizzle.
Proper citation: Scizzle (RRID:SCR_013781) Copy
http://grants.nih.gov/grants/gwas/
http://grants.nih.gov/grants/gwas/
Proper citation: Genome association studies (RRID:SCR_011257) Copy
The Fogarty International Center is dedicated to advancing the mission of the National Institutes of Health by supporting and facilitating global health research conducted by U.S. and international investigators, building partnerships between health research institutions in the U.S. and abroad, and training the next generation of scientists to address global health needs. Fogarty International Center''s programs provide funding to perform research and to train researcher in a variety of global health topics. Through these extensive programs, Fogarty and its partners throughout the National Institutes of Health (NIH) are working to build sustainable research capacity in low- and middle-income countries. Current Programs Research and Research Training Programs * Biodiversity (ICBG) * Bioethics * Brain Disorders * Chronic Diseases: Chronic, Non-communicable Diseases and Disorders Across the Lifespan (NCD-Lifespan); Millennium Promise Awards: Non-communicable Chronic Diseases Research Training (NCoD); Clinical, Operational and Health Services (ICOHRTA) * Ecology and Evolution of Infectious Diseases (EEID) * Environmental and Occupational Health (ITREOH) * Framework * Framework Innovations * Framework Signature Innovations * Global Environmental and Occupational Health (GEOHealth) * Global Infectious Diseases (GID) * HIV: Fogarty HIV Research Training; AIDS International Training and Research (AITRP); Clinical, Operational and Health Services AIDS/TB (IICOHRTA-AIDS/TB) * Informatics (ITGH) * Medical Education Partnership Initiative (MEPI) * New Foreign Investigators (GRIP) * Research Collaboration (FIRCA) * Tobacco * Trauma and Injury * Womens and Girls Health Administrative Grant Supplements Career Development Opportunities for Individuals * Fellows and Scholars Programs: Global Health Fellows and Scholars; Scholars and Fellows (FICRS-F) * Fulbright-Fogarty Fellowships in Public Health * Independent Scientist in Global Health (ISGHA) * Japanese Researcher Fellowships (JSPS) * Junior Research Scientists (IRSDA) Other Programs * American Reinvestment and Recovery Act (ARRA) * Genetics * Population * Stigma
Proper citation: Fogarty International Center (RRID:SCR_011229) Copy
The NIH is comprised of the Office of the Director and 27 Institutes and Centers. The Office of the Director is the central office at NIH. The OD is responsible for setting policy for NIH and for planning, managing, and coordinating the programs and activities of all the NIH components. The NIH Director provides overall leadership to NIH activities in both scientific and administrative matters. Although each institute within the NIH has a separate mission, the NIH Director plays an active role in shaping the agency''s research agenda and outlook. With a unique and critical perspective on the mission of the entire NIH, the Director is responsible for providing leadership to the institutes for identifying needs and opportunities, especially for efforts that involve several institutes. The NIH Director is assisted by the Principal Deputy Director, who shares in the overall direction of the agency''s activities. In carrying out these responsibilities, the NIH Director stays informed about program priorities and accomplishments through regular staff meetings, discussions, and briefing sessions with OD and institute staff. The Director also receives input from: * the extramural scientific community, including both individual researchers and scientific organizations * patient advocacy and voluntary health groups that deal directly with NIH or indirectly through Congress and the media * the Congress and the Administration the Council of Public Representatives, which brings public views to NIH. Ongoing discussions with these groups and others provides the basis for an established framework within which priorities for the agency are identified, reviewed, and justified. Dr. Francis Collins, the NIH Director, has outlined five key themes for NIH: * Applying high throughput technologies to understand fundamental biology, and to uncover the causes of specific diseases * Translating basic science discoveries into new and better treatments * Putting science to work for the benefit of health care reform * Encouraging a greater focus on global health * Reinvigorating and empowering the biomedical research community Program offices in the Office of the Director are responsible for stimulating specific areas of research throughout NIH and for planning and supporting research and related activities. Current program areas are: minority health, women''s health, AIDS research, disease prevention, and behavioral and social sciences research. Program offices within the Office of the Director fund research through the institutes.
Proper citation: NIH Office of the Director (RRID:SCR_012748) Copy
http://www.niaid.nih.gov/Pages/default.aspx
NIAID research strives to understand, treat, and ultimately prevent the myriad infectious, immunologic, and allergic diseases that threaten millions of human lives. Major areas of investigation: * Acquired Immunodeficiency Syndrome (AIDS) * Asthma and Allergic Diseases * Biodefense * Emerging and Re-emerging Infectious Diseases * Enteric Diseases * Fundamental Immunology * Genetics and Transplantation * Immune-Mediated Diseases * Influenza * Pathogen Genomics * Sexually Transmitted Infections (STIs) * Vaccine Development * Drug Research and Development * Antimicrobial Resistance * Minority and Women''s Health
Proper citation: National Institute of Allergy and Infectious Diseases (RRID:SCR_012740) Copy
Supports cross-cutting, trans-NIH programs that require participation by at least two NIH Institutes or Centers (ICs) or would otherwise benefit from strategic planning and coordination. The requirements for the Common Fund encourage collaboration across the ICs while providing the NIH with flexibility to determine priorities for Common Fund support. To date, the Common Fund has been used to support a series of short term, exceptionally high impact, trans-NIH programs known collectively as the NIH Roadmap for Medical Research. The Common Fund is coordinated by the Office of Strategic Coordination, one of the six offices of the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) within the Office of the Director. The intent of NIH Common Fund programs is to provide a strategic and nimble approach to address key roadblocks in biomedical research that impede basic scientific discovery and its translation into improved human health. In addition, these programs capitalize on emerging opportunities to catalyze the rate of progress across multiple biomedical fields. Common Fund programs are expected to transform the way a broad spectrum of health research is conducted. Initiatives that comprise Common Fund programs are intended to be catalytic in nature by providing limited term investments in strategic areas to stimulate further research through IC-funded mechanisms.
Proper citation: NIH Common Fund (RRID:SCR_012790) Copy
Established in 1986, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) was established in 1986. The mission of the NIAMS is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases. The Institute also conducts and supports basic research on the normal structure and function of bones, joints, muscles, and skin. Basic research involves a wide variety of scientific disciplines, including immunology, genetics, molecular biology, structural biology, biochemistry, physiology, virology, and pharmacology. Clinical research includes rheumatology, orthopaedics, dermatology, metabolic bone diseases, heritable disorders of bone and cartilage, inherited and inflammatory muscle diseases, and sports and rehabilitation medicine.
Proper citation: National Institute of Arthritis and Musculoskeletal and Skin Diseases (RRID:SCR_012715) Copy
http://sigs.nih.gov/biospecimens/Pages/default.aspx
The mission of the Biospecimens Interest Group is to serve as an educational and tutorial vehicle for disseminating information, best practices, regulations, and ethical/legal information formulated and issued by various NIH offices, federal agencies and other leading biospecimens organizations. Please join our listserv so we can inform you about the date, time and the place for future meetings, speakers, website and other activities --- https://list.nih.gov/cgi-bin/wa?SUBED1=biospecimens&A=1. Meetings and seminars are videocast. Vision: #. To create a place where all stakeholders may exchange scientific data, ideas, and information concerning the creation and use of high quality biospecimens for research, assay validation, technology development and other appropriate uses. #. To promote and facilitate interaction between NIH intramural and extramural stakeholders who are interested in and involved with a variety of clinically-oriented, translational research projects using high quality biospecimens. #. To encourage leading stakeholders to address critical elements in study design and statistical analysis of data to facilitate the production of accurate, optimal, and clinically meaningful results (best outcome). #. To educate stakeholders about the potential barriers and obstacles that may obstruct the sharing and collaboration between stakeholders across different organizations and countries. #. To increase the awareness for the necessity of high quality biospecimens and the harmonization, and when appropriate, standardized procedures (best practices, SOPs) for annotating, collecting, transporting, processing, storing, and sharing biospecimens to ensure optimal reproducibility of outcomes and the privacy of the patients (donors) through adherence to the ethical and legal requirements associated with the use of biospecimens. #. To provide the connectivity to various biorepositories and biospecimens around the world, especially those containing rare and difficult to get biospecimens.
Proper citation: NIH Biospecimens Interest Group (RRID:SCR_004903) Copy
http://www.ninds.nih.gov/research/index.htm
The National Institute of Neurological Disorders and Stroke (NINDS) conducts and supports research on brain and nervous system disorders. Created by the U.S. Congress in 1950, NINDS is one of the more than two dozen research institutes and centers that comprise the National Institutes of Health (NIH). NINDS has occupied a central position in the world of neuroscience for more than 50 years. It provides access to different research programs both extramural and intramural. Research Topics: Epilepsy, Parkinson''s Disease, Traumatic Brain Injury, Anticonvulsant Screening, CounterACT, Bioengineering, Neural Interfaces, Stem Cell Research. Offices and Programs: *Channels, Synapses and Neural Circuits *Neural Environment *Neurodegeneration *Neurogenetics *Office of Clinical Research *Office of International Activities *Office of Minority Health and Research *Office of Translational Research *Office of Training and Career Development *Repair and Plasticity *Systems and Cognitive Neuroscience
Proper citation: National Institutes of Neurological Disorders and Stroke Research Programs (RRID:SCR_007209) Copy
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