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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
PeakSeq
 
Resource Report
Resource Website
10+ mentions
PeakSeq (RRID:SCR_005349) PeakSeq software resource A software program for identifying and ranking peak regions in ChIP-Seq experiments. It takes as input, mapped reads from a ChIP-Seq experiment, mapped reads from a control experiment and outputs a file with peak regions ranked with increasing Q-values. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Yale University; Connecticut; USA
PMID:19122651 biotools:peakseq, OMICS_00453 https://bio.tools/peakseq SCR_005349 SciCrunch Registry 2026-10-24 12:45:25 39
TIGRFAMS
 
Resource Report
Resource Website
100+ mentions
TIGRFAMS (RRID:SCR_005493) JCVI TIGRFAMS, TIGRFAM data or information resource, data set, database Consists curated multiple sequence alignments, Hidden Markov Models (HMMs) for protein sequence classification, and associated information designed to support automated annotation of (mostly prokaryotic) proteins. Starting with release 10.0, TIGRFAMs models use HMMER3, which provides excellent search speed as well as exquisite search sensitivity. See the "TIGRFAMs Complete Listing" page to review the accession, protein name, model type, and EC number (if assigned) of all models. TIGRFAMs is a member database in InterPro. The HMM libraries and supporting files are available to download and use for free from our FTP site. sequence alignment, hidden markov model, protein sequence, classification, protein, protein family, sequence homology, sequence, homology, function, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: InterPro
is related to: InterPro
has parent organization: J. Craig Venter Institute
PMID:23197656 Free nif-0000-03560, OMICS_01700, biotools:tigrfams https://bio.tools/tigrfams http://www.tigr.org/TIGRFAMs SCR_005493 SciCrunch Registry TIGRFAMs 2026-10-24 12:45:27 142
Segemehl
 
Resource Report
Resource Website
10+ mentions
Segemehl (RRID:SCR_005494) Segemehl software resource A software to map short sequencer reads to reference genomes. It is able to detect not only mismatches but also insertions and deletions. Furthermore, it is not limited to a specific read length and is able to mapprimer- or polyadenylation contaminated reads correctly. segemehl implements a matching strategy based on enhanced suffix arrays (ESA). Segemehl now supports the SAM format, reads gziped queries to save both disk and memory space and allows bisulfite sequencing mapping and split read mapping. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: ANNOgesic
has parent organization: University of Leipzig; Saxony; Germany
PMID:24512684
PMID:22581174
PMID:19750212
DOI:10.1371/journal.pcbi.1000502
Acknowledgement requested, Free, Public biotools:segemehl, OMICS_00683 https://bio.tools/segemehl, https://sources.debian.org/src/segemehl/ SCR_005494 SciCrunch Registry segemehl - short read mapping with gaps 2026-10-24 12:45:27 48
PASS
 
Resource Report
Resource Website
1000+ mentions
PASS (RRID:SCR_005490) PASS software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 19, 2020.A program to align short sequences that has been developed with an innovative strategy to perform fast gapped and ungapped alignment onto a reference sequence. It supports several data formats and allows the user to modulate very finely the sensitivity of the alignments. The program is designed to handle huge amounts of short reads generated by ILLUMINA, SOLiD and Roche-454 technology. The optimization of the internal data structure and a filter based on precomputed short-word alignments allow the program to skip false positives in the extension phase, thus reducing the execution time without loss of sensitivity. The final alignment is performed by dynamic programming., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: PASS-bis
has parent organization: University of Padua; Padua; Italy
PMID:19218350 THIS RESOURCE IS NO LONGER IN SERVICE biotools:pass, OMICS_00673 https://bio.tools/pass SCR_005490 SciCrunch Registry PASS: a program to align short sequences 2026-10-24 12:45:27 2085
Maq
 
Resource Report
Resource Website
50+ mentions
Maq (RRID:SCR_005485) Maq software resource A set of programs that map and assemble fixed-length Solexa/SOLiD reads in a fast and accurate way. command-line, curses/ncurses, opengl, c, c++, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: SourceForge
DOI:10.1101/gr.078212.108 GNU General Public License, v2 OMICS_00668, biotools:maq https://bio.tools/maq, https://sources.debian.org/src/maq/ SCR_005485 SciCrunch Registry mapass2, Mapping and Assembly with Quality, Mapping and Assembly with Qualities, Maq: Mapping and Assembly with Qualities 2026-10-24 12:45:27 74
ea-utils
 
Resource Report
Resource Website
100+ mentions
ea-utils (RRID:SCR_005553) ea-utils software resource Command-line software tools for processing biological sequencing data. Barcode demultiplexing, adapter trimming, etc. Primarily written to support an Illumina based pipeline - but should work with any FASTQs. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.2174/1875036201307010001 MIT License OMICS_01041, biotools:ea-utils https://bio.tools/ea-utils, https://sources.debian.org/src/ea-utils/ SCR_005553 SciCrunch Registry ea-utils: FASTQ processing utilities 2026-10-24 12:45:28 289
MethylExtract
 
Resource Report
Resource Website
10+ mentions
MethylExtract (RRID:SCR_005446) MethylExtract software resource A user friendly software tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation. bisulfite sequencing, methylation map, methylation, sequence variation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Granada; Granada; Spain
Acknowledgement requested biotools:methylextract, OMICS_00605 https://bio.tools/methylextract SCR_005446 SciCrunch Registry High-Quality methylation maps and SNV calling from BS-Seq experiments 2026-10-24 12:45:27 14
GobyWeb
 
Resource Report
Resource Website
1+ mentions
GobyWeb (RRID:SCR_005443) GobyWeb software resource Web application that facilitates the management and analysis of high-throughput sequencing (HTS) data. In the back-end, it uses the Goby framework, BWA, STAR, Last, GSNAP, Samtools, VCF-tools, along with a cluster of servers to provide rapid alignment and efficient analyses. GobyWeb makes it possible to analyze hundreds of samples in consistent ways without having to use command line tools. GobyWeb provides tools that streamline frequent data analyses for RNA-Seq, Methyl-Seq, RRBS, or DNA-Seq datasets and to enable teams of investigators to share reads and results of analyses. GobyWeb can be extended for new analyses by developing plugins. high-throughput sequencing, gene expression, dna methylation, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Weill Cornell Medical College; New York; USA
PMID:23936070 Acknowledgement requested, GNU Lesser General Public License, v3 OMICS_00601, biotools:gobyweb https://bio.tools/gobyweb SCR_005443 SciCrunch Registry 2026-10-24 12:45:26 3
Bowtie
 
Resource Report
Resource Website
10000+ mentions
Bowtie (RRID:SCR_005476) alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Software ultrafast memory efficient tool for aligning sequencing reads. Bowtie is short read aligner. sequence, analysis, long, reference, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools is used by: deFuse
is used by: Short Read Sequence Typing for Bacterial Pathogens
is used by: TopHat
is used by: BS Seeker
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Bowtie 2
has parent organization: Johns Hopkins University; Maryland; USA
is required by: RelocaTE
Amazon Web Services in Education Research ;
NHGRI R01 HG006102;
NIGMS R01 GM083873
PMID:19261174
DOI:10.1186/gb-2009-10-3-r25
Free, Available for download, Freely available biotools:bowtie, OMICS_00653 https://github.com/BenLangmead/bowtie, https://bio.tools/bowtie, https://sources.debian.org/src/bowtie/ SCR_005476 SciCrunch Registry 2026-10-24 12:45:27 13799
TreQ
 
Resource Report
Resource Website
TreQ (RRID:SCR_005505) TreQ software resource A software read mapper for high-throughput DNA sequencing reads, in particular one to several hundred nucleotides in length, and for large edit distance between sequencing read and match in the reference genome. It can cope particularly well with indels for single-best hit recall of 200nt reads simulated from the human reference genome. TreQ performs best at a running time comparable to BWA at large edit distance settings. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Rutgers University; New Jersey; USA
PMID:22962448 GNU General Public License OMICS_00695, biotools:treq https://bio.tools/treq SCR_005505 SciCrunch Registry TreQ: Indel-tolerant Read Mapper 2026-10-24 12:45:28 0
MicrobesOnline
 
Resource Report
Resource Website
100+ mentions
MicrobesOnline (RRID:SCR_005507) MicrobesOnline analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software resource, source code MicrobesOnline is designed specifically to facilitate comparative studies on prokaryotic genomes. It is an entry point for operon, regulons, cis-regulatory and network predictions based on comparative analysis of genomes. The portal includes over 1000 complete genomes of bacteria, archaea and fungi and thousands of expression microarrays from diverse organisms ranging from model organisms such as Escherichia coli and Saccharomyces cerevisiae to environmental microbes such as Desulfovibrio vulgaris and Shewanella oneidensis. To assist in annotating genes and in reconstructing their evolutionary history, MicrobesOnline includes a comparative genome browser based on phylogenetic trees for every gene family as well as a species tree. To identify co-regulated genes, MicrobesOnline can search for genes based on their expression profile, and provides tools for identifying regulatory motifs and seeing if they are conserved. MicrobesOnline also includes fast phylogenetic profile searches, comparative views of metabolic pathways, operon predictions, a workbench for sequence analysis and integration with RegTransBase and other microbial genome resources. The next update of MicrobesOnline will contain significant new functionality, including comparative analysis of metagenomic sequence data. Programmatic access to the database, along with source code and documentation, is available at http://microbesonline.org/programmers.html. microbe, genome, bacteria, archaea, fungi, prokaryote, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
DOE DE-AC02-05CH11231 PMID:19906701 nlx_144607, biotools:microbesonline https://bio.tools/microbesonline SCR_005507 SciCrunch Registry Microbial Genomics Database, Microbes Online 2026-10-24 12:45:28 166
DiProGB
 
Resource Report
Resource Website
1+ mentions
DiProGB (RRID:SCR_005651) DiProGB software resource Genome browser that encodes the genome sequence by physico-chemical dinucleotide properties such as stacking energy, melting temperature or twist angle. Analyses can be performed for the + and ?, as well as for the double strand. genome, browser, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Dinucleotide Property Database
PMID:19605418 Free, Freely available biotools:diprogb, OMICS_00880 https://bio.tools/diprogb SCR_005651 SciCrunch Registry DiProGB - The Dinucleotide Properties Genome Browser, Dinucleotide Properties Genome Browser 2026-10-24 12:45:30 4
Bambino
 
Resource Report
Resource Website
1+ mentions
Bambino (RRID:SCR_005649) Bambino analysis service resource, data analysis service, production service resource, service resource, software resource A variant detector and graphical alignment viewer for next-generation sequencing data in the SAM/BAM format, which is capable of pooling data from multiple source files. Bambino may be launched online via Java Web Start or downloaded and run locally. java, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: National Cancer Institute
PMID:21278191 Https://cgwb.nci.nih.gov/goldenPath/bamview/documentation/Bambino_Click-thru-agreement-for-executable_final.txt OMICS_00876, biotools:bambino https://bio.tools/bambino SCR_005649 SciCrunch Registry Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format 2026-10-24 12:45:30 5
BS Seeker
 
Resource Report
Resource Website
1+ mentions
BS Seeker (RRID:SCR_005641) data analysis software, data processing software, sequence analysis software, software application, software resource Software which performs accurate and fast mapping of bisulfite-treated short reads. Supplementary information and examples are provided on the site. bisulfite sequencing, sequence analysis software, short read, sequence mapping, bio.tools uses: Bowtie
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Bs-Seeker2
has parent organization: University of California at Los Angeles; California; USA
PMID:20416082 Free, Available for download, Freely available OMICS_00578, biotools:bs_seeker https://bio.tools/bs_seeker SCR_005641 SciCrunch Registry Bisulfite Sequence Seeker 2026-10-24 12:45:30 3
eTRIKS
 
Resource Report
Resource Website
10+ mentions
eTRIKS (RRID:SCR_003765) eTRIKS consortium, data or information resource, organization portal, portal, service resource Research informatics and analytics platform for the IMI OncoTrack consortium. data sharing, drug discovery, translational research, informatics, knowledge management, metadata standard, platform, analytics, tool development, bio.tools uses: tranSMART
is used by: U-BIOPRED
is used by: Predict-TB
is used by: OncoTrack
is used by: ABIRISK
is used by: RA MAP
is listed by: Consortia-pedia
is listed by: Debian
is listed by: bio.tools
is related to: Roche
is related to: Janssen Research and Development
is related to: Merck
is related to: Pfizer Animal Genetics
is related to: Imperial College London; London; United Kingdom
is related to: French National Center for Scientific Research
is related to: Clinical Data Interchange Standards Consortium
is related to: University of Luxembourg; Luxembourg; Luxembourg
is related to: IDBS
is related to: BioSci Consulting
is related to: TraIT
is related to: EMIF
is related to: Open PHACTS
has parent organization: Imperial College London; London; United Kingdom
Innovative Medicines Initiative ;
EFPIA
PMID:29482119 biotools:eTRIKS, nlx_158034 https://bio.tools/eTRIKS SCR_003765 SciCrunch Registry European Translational Information and Knowledge Management Services, European Translational Information & Knowledge Management Services 2026-10-24 12:45:01 11
RAREMETAL
 
Resource Report
Resource Website
10+ mentions
RAREMETAL (RRID:SCR_003573) RAREMETAL software resource A software program that facilitates the meta-analysis of rare variants from genotype arrays or sequencing. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Michigan; Ann Arbor; USA
PMID:24894501 biotools:raremetal, OMICS_00243 https://bio.tools/raremetal SCR_003573 SciCrunch Registry 2026-10-24 12:45:00 22
SeWeR - SEquence analysis using WEb Resources
 
Resource Report
Resource Website
SeWeR - SEquence analysis using WEb Resources (RRID:SCR_004167) data or information resource, portal, service resource, software resource, topical portal Sequence analysis using Web Resources (SeWeR) is an integrated, Dynamic HTML (DHTML) interface to commonly used bioinformatics services available on the World Wide Web. It is highly customizable, extendable, platform neutral, completely server-independent and can be hosted as a web page as well as being used as stand-alone software running within a web browser. It doesn''t require any server to host itself. The goal of SeWeR is to turn your web-browser into a powerful sequence-analysis tool. It is written entirely in JavaScript1.2. SeWeR can be downloaded and mirrored freely. The whole package is just around 300K. You can even run it from a floppy. SeWeR is not compatible with Netscape 6. SeWeR now generates graphics. Savvy is a plasmid drawing software that generates plasmid map in the revolutionary Scalable Vector Graphics format from W3C. nucleic acid, protein, pcr, alignment, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Centre for Cellular and Molecular Biology; Hyderabad; India
PMID:11395442 biotools:sewer, nlx_18981 https://bio.tools/sewer SCR_004167 SciCrunch Registry SEquence analysis using WEb Resources, SeWeR 2026-10-24 12:45:08 0
PerM
 
Resource Report
Resource Website
50+ mentions
PerM (RRID:SCR_004223) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package to perform highly efficient genome scale alignments for hundreds of millions of short reads produced by the ABI SOLiD and Illumina sequencing platforms. It capable of providing full sensitivity for alignments within 4 mismatches for 50bp SOLID reads and 9 mismatches for 100bp Illumina reads.Efficient mapping of short sequencing reads with periodic full sensitive spaced seeds. Short sequencing mapping, short sequencing read, next-generation sequencing, genome, alignment, short read, abi, solid, illumina, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Clippers
has parent organization: Google Code
has parent organization: University of Southern California; Los Angeles; USA
PMID:19675096
DOI:10.1093/bioinformatics/btp486
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00675, biotools:perm https://bio.tools/perm, https://sources.debian.org/src/perm/ SCR_004223 SciCrunch Registry PERiodic seed Mapping, Periodic seed Mapping 2026-10-24 12:45:09 60
TAGS
 
Resource Report
Resource Website
100+ mentions
TAGS (RRID:SCR_004294) TAGS data analysis software, data processing software, software application, software resource, time-series analysis software Software tool for gene set enrichment analysis for expression time series, which can incorporate existing knowledge and analyze the dynamic property of a group of genes that have functional or structural associations. The installation file is for Windows., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, enrichment analysis, time series, function, structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Tsinghua University; Beijing; China
THIS RESOURCE IS NO LONGER IN SERVICE biotools:tags, nlx_31187 https://bio.tools/tags http://166.111.130.26/member/yliu/TAGS/ SCR_004294 SciCrunch Registry 2026-10-24 12:45:10 139
BSRD
 
Resource Report
Resource Website
10+ mentions
BSRD (RRID:SCR_004249) BSRD data or information resource, data repository, database, service resource, storage service resource A repository for bacterial small regulatory RNA. They welcome you to submit new experimental validated sRNA targets. srna target, srna, small regulatory non-coding rna, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23203879 Acknowledgement requested, The community can contribute to this resource biotools:bsrd, OMICS_01533 https://bio.tools/bsrd SCR_004249 SciCrunch Registry BSRD - Bacterial Small Regulatory RNA Database, Bacterial Small Regulatory RNA Database 2026-10-24 12:45:09 29

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