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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://cran.r-project.org/web/packages/muma/
Software that provides guidelines for the whole process of metabolomic data interpretation, from data pre-processing, to dataset exploration and visualization, to identification of potentially interesting metabolites. Guidelines outline the following processes: preprocessing of high-throughput data (normalization and scalings); principal component analysis with help tool for choosing best-separating principal components and automatic testing for outliers; automatic univariate analysis for parametric and non-parametric data, with generation of specific reports (volcano and box plots); partial least square discriminant analysis (PLS-DA); orthogonal partial least square discriminant analysis (OPLS-DA); Statistical Total Correlation Spectroscopy (STOCSY); and Ratio Analysis Nuclear Magnetic Resonance (NMR) Spectroscopy (RANSY).
Proper citation: MUMA (RRID:SCR_002412) Copy
A suite of software tools for analyzing and manipulating next-generation sequencing datasets, such as FASTQ, BED and BAM format files. These tools provide a stable and modular platform for data management and analysis.
Proper citation: NGSUtils (RRID:SCR_001236) Copy
http://bioconductor.org/packages/release/bioc/html/nondetects.html
Software R package to model and impute non-detects in results of qPCR experiments.Used to directly model non-detects as missing data.
Proper citation: nondetects (RRID:SCR_001702) Copy
http://cran.r-project.org/web/packages/enviPick/
Software for sequential partitioning, clustering and peak detection of centroided LC-MS mass spectrometry data (.mzXML). Interactive result and raw data plot.
Proper citation: enviPick (RRID:SCR_003059) Copy
http://www.ks.uiuc.edu/Research/vmd/
A molecular visualization program for displaying, animating, and analyzing large biomolecular systems using 3-D graphics and built-in scripting. VMD supports computers running MacOS X, Unix, or Windows, is distributed free of charge, and includes source code.
Proper citation: Visual Molecular Dynamics (RRID:SCR_001820) Copy
https://apsampler.sourceforge.net/
A software tool that allows multi-locus and multi-level association analysis of genotypic and phenotypic data.
Proper citation: APSampler (RRID:SCR_000042) Copy
https://cran.r-project.org/src/contrib/Archive/MetaDE/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30, 2022. Software package that implements 12 major meta-analysis methods for differential expression analysis.Package was removed from the CRAN repository.Formerly available versions can be obtained from the archive.Archived on 2018-01-23 as check problems were not corrected in time.
Proper citation: MetaDE (RRID:SCR_000199) Copy
http://open2dprot.sourceforge.net/Flicker/
An open-source stand-alone computer program for visually comparing 2D gel images.
Proper citation: Flicker (RRID:SCR_000288) Copy
http://cutenmr.sourceforge.net/
A multi-platform NMR processing application.
Proper citation: cuteNMR (RRID:SCR_000347) Copy
http://sourceforge.net/projects/jmoldraw/
2-D chemical structure drawing software program.
Proper citation: JMolDraw (RRID:SCR_000349) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowFlowJo.html
A Bioconductor package that can import gates defined by the commercial package FlowJo and work with them in a manner consistent with the other flow packages in Bioconductor. FlowJo is a commercial GUI based software package from TreeStar Inc. for the visualization and analysis of flow cytometry data. One of the FlowJo standard export file types is the FlowJo Workspace. This is an XML document that describes files and manipulations that have been performed in the FlowJo GUI environment. This package can take apart the FlowJo workspace and deliver the data into R in the flowCore paradigm.
Proper citation: flowFlowJo (RRID:SCR_000410) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowStats.html
Software using statistical methods and functionality to analyze flow data that is beyond the basic infrastructure provided by the flowCore package.
Proper citation: flowStats (RRID:SCR_000399) Copy
http://www.bioconductor.org/packages/release/bioc/html/iBMQ.html
Software for integrated Bayesian Modeling of eQTL data. It implements a joint hierarchical Bayesian model where all genes and SNPs are modeled concurrently.
Proper citation: iBMQ (RRID:SCR_000481) Copy
http://www.uwyo.edu/buerkle/software/bamova/
Software that implements a Bayesian Analysis of Molecular Variance and different likelihood models for three different types of molecular data (including two models for high throughput sequence data).
Proper citation: bamova (RRID:SCR_000510) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowQ.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. Software that provides quality control and quality assessment tools for flow cytometry data.
Proper citation: flowQ (RRID:SCR_000575) Copy
http://www.bioconductor.org/packages/release/bioc/html/SigFuge.html
Algorithm for testing significance of clustering in RNA-seq data.
Proper citation: SigFuge (RRID:SCR_000444) Copy
https://code.google.com/p/jmzidentml/
A Java application programming interface (API) for the Human Proteome Organisation (HUPO) Proteomics Standards Initiative (PSI) mzIdentML standard for peptide and protein identification data.
Proper citation: jmzIdentML API (RRID:SCR_000878) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowWorkspace.html
Software package that facilitates comparison of automated gating methods against manual gating done in flowJo. This package allows you to import basic flowJo workspaces into BioConductor and replicate the gating from flowJo using the flowCore functionality. Gating hierarchies, groups of samples, compensation, and transformation are performed so that the output matches the flowJo analysis.
Proper citation: flowWorkspace (RRID:SCR_001155) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Open source viewer / browser software for the SAM / BAM format commonly used in the assembly tasks of Next Generation Sequencing data.
Proper citation: GenoViewer (RRID:SCR_001203) Copy
http://www.bioinformatics.org/peakanalyzer/wiki/
A set of standalone software programs for the automated processing of any genomic loci, with an emphasis on datasets consisting of ChIP-derived signal peaks. The software is able to identify individual binding / modification sites from enrichment loci, retrieve peak region sequences for motif discovery, and integrate experimental data with different classes of annotated elements throughout the genome. PeakAnalyzer requires a peak file and a feature annotation file in BED or GTF format. Complete annotation files for the current builds of the human (HG19) and mouse (MM9) genomes are provided with the software distribution.
Proper citation: PeakAnalyzer (RRID:SCR_001194) Copy
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