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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://cran.r-project.org/web/packages/evora/
R package for quantifying variation in DNA methylation as a cancer biomarker.
Proper citation: EVORA (RRID:SCR_007329) Copy
http://www.nia.nih.gov/research/dab/nia-mutant-mouse-aging-colony-handbook
THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 09, 2013. Supply aged mutant and transgenic mice for NIH-supported research directly related to the biology of aging. The mice are raised by the NIA's contractor, Taconic Farms, in Specific Pathogen-Free (SPF) barrier facilities. The strains in the mutant mouse aging colony have been donated by the investigators who developed the models, and those investigators are still the legally recognized owners of the intellectual property. A Material Transfer Agreement (MTA) is required to purchase the mice (a one-time requirement per strain). There are restrictions to the use of this colony as described in the MTA. These restrictions include a prohibition against breeding the mice purchased from the NIA Mutant Mouse Aging Colony, agreement that the mice will not be used for commercial purposes, and agreement that the mice and all derivatives will not be transferred to third parties. The restrictions are further spelled out in the MTA. Animals are sold by age, not weight, and ages are stated in 1 month intervals only; all animals born within a calendar month are considered to be the same age, so date of birth (DOB) is given as month/year. All mice are virgins. The mutant mouse aging colony is slated to end in September 2013. Old mice will be available until September 2013 but the availability of young mice will end earlier. Entries of different strains into the mutant mouse aging colony will end at different times, dependent on the lifespan and pattern of use of the strain. Mouse models include: * Snell Dwarf (3623) ??????????????? last entry will be the November 2011 DOB (date of birth) * Ames Dwarf (324) ??????????????? last entry will be the October 2012 DOB * A53T ???????????????????????-synuclein Transgenic (322) ??????????????? last entry will be the December 2012 DOB * GFP Transgenic (317) ??????????????? last entry will be the January 2013 DOB
Proper citation: NIA Mutant Mouse Aging Colony Handbook (RRID:SCR_007328) Copy
Collects, stores, and distributes samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals. The NNTC mission is to bolster research on the effects of HIV infection on human brain by providing high-quality, well-characterized tissue samples from patients who died with HIV, and for whom comprehensive neuromedical and neuropsychiatric data were gathered antemortem. Researchers can request tissues from patients who have been characterized by: * degree of neurobehavioral impairment * neurological and other clinical diagnoses * history of drug use * antiretroviral treatments * blood and CSF viral load * neuropathological diagnosis The NNTC encourages external researchers to submit tissue requests for ancillary studies. The Specimen Query Tool is a web-based utility that allows researchers to quickly sort and identify appropriate NNTC specimens to support their research projects. The results generated by the tool reflect the inventory at a previous time. Actual availability at the local repositories may vary as specimens are added or distributed to other investigators.
Proper citation: National NeuroAIDS Tissue Consortium (RRID:SCR_007323) Copy
http://seurat.r-forge.r-project.org/
Software tool which provides interactive visualization capability for the integrated analysis of high-dimensional gene expression data. Visual analytics for the integrated analysis of microarray data.
Proper citation: SEURAT (RRID:SCR_007322) Copy
Website with multiple information including curent news and publications, clinical trials, and a mitochondria database. :clinical trials related to mitochondria; publications related to mitochondria, mitochondria database : :
Proper citation: Mitochondria News and Research (RRID:SCR_007325) Copy
http://www.nih.gov/science/models/
Information about national and international activities and major resources that are being developed to facilitate biomedical research using animal models Mammalian Models: * Mouse * Rat Non-Mammalian Models * S. cerevisiae (budding yeast) * S.pombe (Fission Yeast) * Neurospora (filamentous fungus) * D. discoideum (social amoebae) * C. elegans (round worm) * Daphnia * D. melanogaster (fruit fly) * D. rerio (zebrafish) * Xenopus (frog) * Gallus (chicken) Other Model Organisms: * Arabidopsis
Proper citation: Model Organisms for Biomedical Research (RRID:SCR_007282) Copy
Portal to neurogenetic resources: the mouse brain library, digital atlases of the mouse brain, extensive brain microarray data in WebQTL, and internet access to microscopes and stereology tools.Mouse Brain Library. Mouse Brain Library is an expanding collection of high-resolution histological images, atlases, MRIs, and databases on brain structure of more than 120 different lines of mice. Nervenet also includes several useful genetics and gene mapping databases to download (SNP databases, Map Manager databases, and the Portable Dictionary of the Mouse Genome). The publications section includes revised, expanded, and annotated papers, tutorials, and reviews on neurogenetics, gene mapping, complex trait analysis, stereology, and the control of neuron number.
Proper citation: Neurogenetics Online (RRID:SCR_007280) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 19, 2015. Commercial brain atlases distributed by Theime Medical Publishers. It supports a complete electronic version of the Talairach Atlas, as well as gyral-level description of the human brain and atlases for cerebral vasculature, cranial nerves and a probabilistic functional atlas. In addition, this tool permits the incorporation of user image data, both structural and functional, into the viewer for direct co-visualization with the atlas. This CD-ROM provides numerous tools for the analysis of functional images: It contains the fully color-coded and labeled Talairach-Tournoux brain atlas in the axial, coronal and sagittal orientations, along with Brodmann''s areas and gyri in the axial orientation. -Allows anatomical and functional images to be loaded and registered. -Enables interactive placement of the Talairach landmarks in 3D Space. -Provides automatic data-to-atlas warping based on the Talairaich proportional grid system transformation. In addition, real-time interactive warping for fine tuning is available. -Allows the user to place marks on the activation loci in the warped functional images, display these marks with the atlas, and edit them simultaneously on the axial, cornal and sagittal orientations. Mark placement is assisted by a grey-value thresholding feature. -Provides simultaneous display of the atlas, anatomical image and functional image withing one interactively blended image. Atlas-data blending and anatomical-functional image blending are controlled independently. -Labels the data by means of the atlas. The atlas can be flipped left/right so that Brodmann''s areas areas and gyri can be labeled on both hemispheres. -Provides additional functions such as friendly navigation, simultaneous display of axial, coronal and sagittal atlas plates, cross-referenced display, image and atlas sequencing, readout of the Talairach coordinates and intensities, save, print, help.
Proper citation: Brain Atlas for Functional Imaging (RRID:SCR_007356) Copy
https://www.icts.uiowa.edu/confluence/dashboard.action
A group of software packages for image analysis, mainly used in MRI image processing. BRAINS (Brain Research: Analysis of Images, Networks, and Systems) contains manual and automated tools for structural identification and methods for tissue classification and cortical surface generation. BRAINS2 is most commonly used to analyze magnetic resonance (MR) scans, but the package can also be used to analyze images acquired with positron emission tomography (PET), single photon emission computed tomography (SPECT), and functional magnetic resonance (fMR). It is implemented in an object-oriented, cross-platform compatible manner and includes a toolbar and command line interface, a graphical interface, and a computational kernel.
Proper citation: Brain Research: Analysis of Images, Networks and Systems (RRID:SCR_007357) Copy
BrainVISA is a modular an customizable software platform built to host heterogeneous tools dedicated to neuroimaging research. Many toolboxes have already been developed for BrainVISA (T1 MRI, sulcal identification and morphometry, cortical surface analysis, diffusion imaging and tractography, fMRI, nuclear imaging, EEG and MEG, TMS, histology and autoradiography, etc.). Anatomist is a software for interactive visualization of multimodal data and for manipulation of structured 3D objects. It allows to build scenes that merge or combine images, meshes, regions of interest, fibers, textures, color palettes, referential changes, etc. A user can interact in 3D and in real time with the objects of an Anatomist scene: change point of view, select objects, add/suppress objects, change colors, draw regions of interests, do manual registration, etc. BrainVISA main features are: * Harmonization of communications between different software. For instance, BrainVISA toolboxes are using home-made software but also third-party software such as FreeSurfer, FSL, SPM, nipy, R-project, Matlab, etc. * Ontology-based data organization allowing database sharing and automation of mass of data analysis. * Fusion and interactive visualization of multimodal data (using Anatomist software). * Automatic generation of graphical user interfaces. * Workflow monitoring and data quality checking. * Full customization possible. * Runs on Linux, Mac and Windows. * Programming Language: C++, Python * Supported Data Format: ANALYZE, DICOM, GIfTI, MINC, NIfTI-1, Other Format
Proper citation: BrainVISA / Anatomist (RRID:SCR_007354) Copy
http://www.fei.com/software/amira-3d-for-life-sciences/
Software tool for visualizing, manipulating, and understanding data from tomography, microscopy, MRI and other imaging processes.Used to import and export options, to processes 3D image filtering and DTI based fiber tracking to visualization, volume and surface rendering, author tools for virtual reality navigation, video generation, and more.
Proper citation: Advanced 3D Visualization and Volume Modeling (RRID:SCR_007353) Copy
DICOMscope is a free DICOM viewer which can display uncompressed, monochrome DICOM images from all modalities and which supports monitor calibration according to DICOM part 14 as well as presentation states. The application is rather a feasibility study for DICOM presentation states. DICOMscope offers a print client (DICOM Basic Grayscale Print Management) which also implements the optional Presentation LUT SOP Class.
Proper citation: DICOMscope (RRID:SCR_007344) Copy
Center that acquires, maintains, and distributes genetic stocks and information about stocks of the small free-living nematode Caenorhabditis elegans for use by investigators initiating or continuing research on this genetic model organism. A searchable strain database, general information about C. elegans, and links to key Web sites of use to scientists, including WormBase, WormAtlas, and WormBook are available.
Proper citation: Caenorhabditis Genetics Center (RRID:SCR_007341) Copy
http://fmri.wfubmc.edu/software/PickAtlas
A software toolbox that provides a method for generating Region of Interest (ROI) masks based on the Talairach Daemon database. The atlases include Brodmann area, Lobar, Hemisphere, Anatomic Label (gyral anatomy), and Tissue type. The atlases have been extended to the vertex in MNI space, and corrected for the precentral gyrus anomaly. Additional atlases (including non-human atlases) can be added without difficulty., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: WFU PickAtlas (RRID:SCR_007378) Copy
https://ranchobiosciences.com/
Company offers Data Curation, Data Governance and Models, Bioinformatics Analysis, Workflows and Pipelines, Knowledge Mining, Target Profiles, Building Databases with content, Business Analyst services to clients in Pharmaceutical and Biotech companies, Foundations, Government and Hospitals.
Proper citation: RanchoBiosciences (RRID:SCR_007252) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. A database tool that allows for any combination of the Boolean operations union/disjunction (OR), intersection/conjunction (AND), and subtraction/negation (NOT) to be performed on multiple datasets. Booly brings the power of biological data integration to the researcher by helping researchers analyze and integrate their data. Booly offers a simple contribution model, where users can simply cut and paste spreadsheet data to create new datasets that could thereafter be stored, shared, and compared. Users may also take advantage of publically available datasets created by other members such as Gene Ontology datasets and species-species BLAST datasets.
Proper citation: Booly: A Resource for Biological Data Integration (RRID:SCR_007373) Copy
Portal for Macromolecular X-Ray Crystallography to produce and support an integrated suite of programs that allows researchers to determine macromolecular structures by X-ray crystallography, and other biophysical techniques. Used in the education and training of scientists in experimental structural biology for determination and analysis of protein structure.
Proper citation: CCP4 (RRID:SCR_007255) Copy
http://www.cmrr.umn.edu/stimulate
An fMRI analysis software package with a GUI (Graphical User Interface) front end. Stimulate offers a comprehensive set of fMRI analysis tools integrated into a single package for convenient and flexible data processing. Users can point and click with the mouse to modify analysis or display variables. Activation maps can be calculated from the fMRI data and overlaid onto structural MRI image displays.
Proper citation: Stimulate (RRID:SCR_007375) Copy
http://www.bitplane.com/imaris/imaris
Imaris provides range of capabilities for working with three dimensional images. Uses flexible editing and processing functions, such as interactive surface rendering and object slicing capabilities. And output to standard TIFF, Quicktime and AVI formats. Imaris accepts virtually all image formats that are used in confocal microscopy and many of those used in wide-field image acquisition. Imaris version 10.1 for image analysis workflows using AI trainable object detection.
Proper citation: Imaris (RRID:SCR_007370) Copy
http://pbil.univ-lyon1.fr/cap3.php
This form allows you to assemble a set of contiguous sequences (contigs) with the CAP3 program. The CAP3 program has a capability to clip 5'' and 3'' low-quality regions of reads. It uses base quality values in computation of overlaps between reads, construction of multiple sequence alignments of reads, and generation of consensus sequences. The program also uses forward-reverse constraints to correct assembly errors and link contigs. Results of CAP3 on four BAC data sets are presented. The performance of CAP3 was compared with that of PHRAP on a number of BAC data sets. PHRAP often produces longer contigs than CAP3 whereas CAP3 often produces fewer errors in consensus sequences than PHRAP. It is easier to construct scaffolds with CAP3 than with PHRAP on low-pass data with forward-reverse constraints. Sponsors: This project was supported by NIH Grant R01HG01502-02 from NHGRI. Keywords: CAP3, Program, Form, Computation, DNA, Dataset, Database, Program,, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CAP3 Sequence Assembly Program (RRID:SCR_007250) Copy
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