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https://www.beatson.gla.ac.uk/advanced-technologies/bair.html

Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.

Proper citation: Beatson Institute for Cancer Research United Kingdom Beatson Advanced Imaging Resource Core Facility (RRID:SCR_023875) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/bsbc/index.html

Core fosters research and teaching activities related to bioinformatics and systems biology at UNMC. Provides infrastructure, resources, and educational training in bioinformatics with ultimate goal of promoting synergistic research activities at the intersection of computational and experimental disciplines. Used to analyze biomolecular datasets including DNA, RNA, proteins, etc.

Proper citation: University of Nebraska Medical Center Bioinformatics and Systems Biology Core Facility (RRID:SCR_023767) Copy   

•   Source: SciCrunch Registry

https://biologics.utexas.edu/research/advanced-protein-therapeutics-core

Core catalyzes translation of scientific discoveries into novel protein cancer therapies. Offers therapeutic antibody and enzyme discovery, engineering, and optimization services.

Proper citation: University of Texas at Austin Advanced Protein Therapeutics Core Facility (RRID:SCR_023740) Copy   

•   Source: SciCrunch Registry

https://www.dartmouth-hitchcock.org/pathology/research#ibr

Institutional resource collaboratively run by Office of Research Operations and Department of Pathology and Laboratory Medicine that provides services in support of Dartmouth Research Communities and in alignment with Institutional Review Board approved protocols including Clinical Trials. Provides collection, processing, storage, and distribution of annotated human bio-specimens to clinicians and other investigators in support of clinical trials, industry sponsored projects, and scientific investigations.

Proper citation: Dartmouth Health Hitchcock Medical Center Biorepository Core Facility (RRID:SCR_023735) Copy   

•   Source: SciCrunch Registry

https://research.utsa.edu/cores/stem-cell-core/

Provides service, advice and training across spectrum of induced pluripotent stem cell workflow, from adult tissue to gene edited differentiated progeny. Provided services include Isolation and cryopreservation of cells from adult tissues, Reprogramming of adult tissues to IPSCs, Full quality control panel ensuring high quality iPSCs, Gene editing of pluripotent stem cells, Custom research utilizing pluripotent stem cells and their 2D and 3D differentiated progeny, Consultation and project planning assistance.

Proper citation: University of Texas at San Antonio Stem Cell Core Facility (RRID:SCR_023748) Copy   

•   Source: SciCrunch Registry

https://bic.nd.edu/

Offers instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for isolation and purification of macromolecules for subsequent detailed biophysical analysis.

Proper citation: University of Notre Dame ND Biophysics Instrumentation Core Facility (RRID:SCR_023867) Copy   

•   Source: SciCrunch Registry

https://boc.wisc.edu/

Core provides instrumentation for light and fluorescence based microscopy, including epifluorescence, confocal, and super-resolution imaging.Provides access to and training on basic and advanced light microscopy techniques. Expertise and advice is available for the design of experiments involving these techniques.

Proper citation: University of Wisconsin-Madison Biochemistry Optical Core Facility (RRID:SCR_023952) Copy   

•   Source: SciCrunch Registry

https://ibt.tamu.edu/centers/translational-cancer-research/stephan-lab/mlots/index.html

Supports lead optimization programs and has established roster of medium throughput microphysiologic screening platforms including tissue- and tumor-on-a-chip platforms, organoid, and spheroid culture systems that will be used to evaluate efficacy and toxicity of new lead compounds and drug combinations.Provides resources to identify toxic liabilities in lead series molecules before entering pre-clinical or clinical testing. MLOTS can evaluate NME for cardiovascular, neuro, or liver toxicity relative to reference standards using in vitro screening platforms. Facility will potentially enhance the effectiveness of CPRITs drug discovery programs.

Proper citation: Texas A and M University Health Institute of Biosciences and Technology Microphysiological Lead Optimization and Toxicity Screening Core Facility (RRID:SCR_023717) Copy   

•   Source: SciCrunch Registry

https://www.sdstate.edu/genomics-sequencing-facility

Facility offers custom sequencing services from DNA/RNA extractions to sequencing using Illumina and Oxford Nanopore platforms. Projects examples include bulk RNAseq, 3\'RNASeq, Single Cell transcriptomics (10X Genomics), Genome sequencing, and amplicon sequencing (ie 16SRNA, genotyping). Services include experimental design and bioinformatics data analysis.

Proper citation: South Dakota State University Genomics Sequencing Core Facility (RRID:SCR_023959) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/cancer/research/shared-resources/biostatistics_research_informatics.html

Core provides statistical support to SCI members by engages them on their data related needs. Specifically, BSR members assist researchers at each stage of study’s lifecycle, including project design, mid study evaluation and interpretation and reporting of results. In addition, BSR members mentor SCI investigators in research methods. BSR assists with development and review of proposed studies and planning of research related data management systems.

Proper citation: Stanford University School of Medicine Cancer Institute Biostatistics Shared Resource Core Facility (RRID:SCR_023696) Copy   

•   Source: SciCrunch Registry

https://www.mri.cnrs.fr

Imaging and cytometry facility of the Montpellier area.

Proper citation: Montpellier Imaging Resources Core Facility (RRID:SCR_023727) Copy   

•   Source: SciCrunch Registry

http://researchservices.pitt.edu/facilities/machine-shop

Core specializes in mechanical design, fabrication, and repair of research equipment and instrumentation.

Proper citation: University of Pittsburgh Dietrich School Machine Shop Core Facility (RRID:SCR_023720) Copy   

•   Source: SciCrunch Registry

https://www.uniklinik-freiburg.de/medizin1/forschung/lighthouse-core-facility.html

Core specializes in areas of flow cytometry and cell sorting; light microscopy including confocal, widefield fluorescence, high content screening, lightsheet, slide scanning, highly multiplexed microscopy; and digital PCR / QPCR. It is located at University of Freiburg Medical Center and hosts institutions including Dept. of Medicine I, Center for Chronic Immunodeficiency (CCI), CCCF / DKTK, and Medical Faculty of University of Freiburg.

Proper citation: University of Freiburg Medical Center Lighthouse Core Facility (RRID:SCR_023785) Copy   

•   Source: SciCrunch Registry

https://www.cch.uleth.ca

Provides comprehensive solution characterization of macromolecules or macromolecular interactions and assemblies. This includes description of stoichiometry, size composition, cargo loading.Core is equipped with analytical ultracentrifuges featuring multi-wavelength UV-visible detection, as well as Rayleigh interference optics and fluorescence emission detection for fluorescent tags with 488 nm excitation.

Proper citation: University of Lethbridge Canadian Center for Hydrodynamics Core Facility (RRID:SCR_023791) Copy   

•   Source: SciCrunch Registry

https://med.miami.edu/research/cores/biomarker-and-immunoassay-laboratory

Provides biomarker testing for human clinilcal research studies across multiple disciplines.Provides expertise with chemistry, special chemistry, radioimmunoassay, nephelometric and ELISA and multiplexing assay methods utilizing automated and manual procedures. Laboratory has Clinical Laboratory Improvement Act certification and follows guidelines established by CLIA for quality control and proficiency testing to ensure results. Core coordinates proper pre-analytical sample collection and processing procedures with project leaders; performs biochemical assays on samples submitted to the laboratory by investigators in manner that assures strict quality control both within and between assay runs; reports results to project staff in timely fashion; makes available expertise and technical assistance for establishing and validating new methodologies to support University of Miami investigators.

Proper citation: University of Miami Miller School of Medicine Biomarkers and Immunoassay Laboratory Core Facility (RRID:SCR_023705) Copy   

•   Source: SciCrunch Registry

https://gtp.med.upenn.edu/core-laboratories-public/vector-core

Resource for investigators requiring viral vectors for preclinical studies and other basic research applications such as gene therapies for acquired and inherited diseases.Provides production of high quality vectors and distribution of improved vector technologies services.

Proper citation: University of Pennsylvania Perelman School of Medicine Vector Core Facility (RRID:SCR_022432) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/labs-and-centers/quantitative/ultrasound-research-laboratory

Develops new ultrasound technologies and clinical applications, to bridge gap between technology and clinical applications, and to provide ultrasound imaging resources to other research. Consists of core group of scientists, sonographers and technicians with expertise in ultrasound technology and computer programming. This group works with clinicians in multiple specialties; including radiologists, cardiologists and surgeons. Core provides ultrasound scanner, sonographer and part-time radiologist on staff to conduct clinical and pre-clinical imaging.Helps with studies involving measurement of angiogenesis, vascularity, tissue elasticity, contrast agents, and effects of various physical and pharmaceutical agents on blood flow and tissue vascularity. Studies include research on cancer, cardiovascular disease and musculoskeletal disease.

Proper citation: University of Pennsylvania Perelman School of Medicine Ultrasound Research Laboratory Core Facility (RRID:SCR_022431) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/cactis-lab

CACTIS mission is to oversee proposed research protocols that involve human, animal, phantom or specimen studies in an effort to achieve two goals, to ensure that all research performed on CT scanners comply with CACTIS and University policy, and Federal Regulations, and to determine if CACTIS can maintain the resources required to carry out each research protocol, including personnel, software, hardware and scan time. Additionally, CACTIS oversees the day-to-day operations of all CT procedures associated with research protocols, provides information regarding the use of CT facilities to the research community at the University of Pennsylvania, provides CACTIS users with all of the policies of the institution governing research, and ensures that CACTIS is in compliance with these policies. The service center strives to support the Perelman School of Medicine�s research endeavors by providing CT research services for a fee designed only to cover actual costs.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Advanced Computer Tomography Imaging Services Core Facility (RRID:SCR_022395) Copy   

•   Source: SciCrunch Registry

https://www.cceb.med.upenn.edu/bac

Provides wide range of biostatistical and epidemiological consulting services.

Proper citation: University of Pennsylvania Perelman School of Medicine Biostatistics Analysis Center Core Facility (RRID:SCR_022393) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-acute-biobanking-core

Core encourages and facilitates microbiome focused research in pathogenesis, diagnosis and treatment of patients with critical illness. Core assists in research by providing de-identified samples with linked clinical metadata to support research in this area, collect specimens as needed in support of microbiome research, and offer support for development of such research in the critical care setting.

Proper citation: University of Pennsylvania Perelman School of Medicine Acute Care Biobanking Core Facility (RRID:SCR_022392) Copy   

•   Source: SciCrunch Registry