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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://research.manchester.ac.uk/en/equipments/biomolecular-nmr-facility/
Core provides advanced NMR spectroscopy for researching the atomic-level structure, dynamics, and interactions of biological macromolecules. It supports structural biology, biocatalysis, and drug discovery by analyzing proteins, DNA, RNA, and carbohydrates. Includes 800MHz NMR spectrometer with H/F-C-N Cryoprobe.
Proper citation: University of Manchester Biomolecular NMR Core Facility (RRID:SCR_028357) Copy
Bruker Invenio S is an entry-level FT-IR spectrometer designed for routine productivity and basic research and development. Analytical instrument that identifies chemical compounds and molecular structures by measuring how samples absorb infrared light. Offers upgradable Invenio platform featuring the Transit channel and MultiTect technology.
Proper citation: Bruker: Invenio S FT-IR Spectrometer (RRID:SCR_028359) Copy
Facility contains equipment for all basic molecular biology needs. Training and help are provided. Provides molecular biology services ranging from DNA preparations to cloning and mutagenesis projects.
Proper citation: University College London Molecular Biology Core Facility (RRID:SCR_028350) Copy
https://www.research.chop.edu/cag-genotyping-core
Core is equipped with liquid handling technology and experienced staff members. Offers both standard and custom Illumina array project design. With the capacity to process >2300 samples/week and generate >480 million genotypes per day, the genotyping core fully integrates with our Biorepository and Bioinformatics group, offering the collaborator the opportunity for a seamless experience from DNA extraction to data release.
Proper citation: Children's Hospital of Philadelphia CHOP CAG Genotyping Core Facility (RRID:SCR_028400) Copy
https://www.research.chop.edu/single-cell-technology-core
Core offers services and access to single-cell, spatial and in situ technologies. Provides instruments, experienced research assistants and bioinformaticians to experimental and computational support. Services include 10x Genomics single cell assays, 10x Genomics Visium CytAssist and Visium HD spatial transcriptomics, 10x Genomics Xenium in situ spatial transcriptomics, Vizgen MERSCOPE in situ spatial transcriptomics, NanoString GeoMx Digital Spatial Profiler RNA and protein assays.
Proper citation: Children's Hospital of Philadelphia CHOP Single Cell Technology Core Facility (RRID:SCR_028401) Copy
https://www.research.chop.edu/chop-high-throughput-sequencing-core
Core is service facility providing instrumentation, library preparation, and sequencing services to CHOP, UPenn, and external investigators in genomic, epigenomic and transcriptomic studies.
Proper citation: Children's Hospital of Philadelphia CHOP High Throughput Sequencing Core Facility (RRID:SCR_028398) Copy
https://www.crukscotlandinstitute.ac.uk/about/research-integrity.html
Core enables and promotes responsible research practices to generate trustworthy data, and to safeguard research data. The service is comprised of 4 pillars; governance, good research practice support, stewardship and knowledge exchange.
Proper citation: Cancer Research UK Scotland Institute Research Integrity Service Core Facility (RRID:SCR_028431) Copy
https://uwhistologyandimaging.org/
Core provides histology, immunohistochemistry, imaging, quantitative image analysis, and pathology consultation services. Offers experience, expertise and instrumentation across all platforms. Through the partnership with the Comparative Pathology Program (CPP), we have board certifies veterinary pathologists on staff who are available for research consultation and collaboration.
Proper citation: University of Washington Histology and Imaging Core Facility (RRID:SCR_028435) Copy
https://sites.google.com/fieldmuseum.org/research/laboratories/core-laboratories/sem
Interdepartmental core facility for scanning electron microscope imaging and elemental analysis of objects. Provides Hitachi SU7000 field emission scanning electron microscope, an Oxford Ultim Max 170 infinity EDS detector with BEX (backscatter electron and X-ray imaging detector), a Leica EM Ace600 sputter coater and a Hitachi IM4000II ion milling system.
Proper citation: Field Museum of Natural History Scanning Electron Microscopy Laboratory Core Facility (RRID:SCR_028394) Copy
https://institutducerveau.org/plateforme-dexploration-preclinique-phenoparc
Core provides infrastructure (A1 and A2 zoned) and technical expertise for standardized husbandry, breeding, experimental use of rodent and health monitoring (SPF and SOPF zones) in compliance with regulatory and ethical guidelines. The platform offers technical services such as Surgery on brain and spinal cord, Behavioral tests (anxiety, depression, cognition, motor/locomotor and visual parameters, spontaneous activity, USV recording etc… ), embryo transfer. Training and technical support are available for rodent handling, experimental design, and data reproducibility.
Proper citation: Paris Brain Institute PhenoICMice Core Facility (RRID:SCR_028531) Copy
https://nyulangone.sharepoint.com/sites/pophealth-data-hub
Core to improve access, efficiency, and support for research teams working with a wide range of data sources to study and address population health issues. Part of data ecosystem of research data hubs and related services at NYULH. Our goal is to help Population Health PIs and Analysts solve their administrative and analysis issues. This includes data acquisition, storage, cleaning, analysis, and dissemination.
Proper citation: New York University Langone Health NYULH Population Health Data Hub Core Facility (RRID:SCR_028492) Copy
Core provides services in design, construction, and production of custom research grade viral vectors for biomedical research including Adeno-associated viral (AAV) vectors, Retroviral vectors (MLV-based), Lentiviral vectors (LV), Virus-Like Particles (VLPs / Nanoblades).
Proper citation: Catholic University of Leuven Viral Vector Core Facility (RRID:SCR_028527) Copy
https://research.ncsu.edu/metric/
Molecular Education, Technology and Research Innovation Center (METRIC) is an NC State University-wide Shared Core Research Facility administered by the Office of Research and Innovation. We provide internal and external researchers with access to instrumentation and technical expertise across three primary analytical platforms: Mass Spectrometry: Supports qualitative and quantitative analyses, including high-resolution accurate mass (HRAM) measurements, proteomics, metabolomics, and small molecule analysis. Magnetic Resonance (NMR & EPR): Provides structural and dynamic characterization of molecules in solution. Capabilities include multi-nuclear solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy for studying paramagnetic species, transition metal complexes, and free radicals. X-Ray Diffraction: Offers atomic-level structural determination. The facility is equipped for single-crystal X-ray diffraction of both small molecules (including absolute configuration determination) and macromolecules/proteins.
Proper citation: North Carolina State University NCSU METRIC Core Facility (RRID:SCR_028548) Copy
Core provides specialized imaging services for primarily biological research, with additional applications for materials chemistry, forensic science, and engineering technology. Available instrumentation includes various light microscopes, a laser-scanning confocal, scanning and transmission electron microscopes, and X-ray imaging.
Proper citation: Sam Houston State University SHSU-Microscopy Core Facility (RRID:SCR_028477) Copy
Core for high resolution imaging and structural analysis of biological specimens, soft matter, and nanomaterials. Used to process samples from solution or powder, allowing researchers to visualize internal structures down to the subnanometer scale. It is critically important that the samples are non-magnetic.
Proper citation: University College London Mathematical and Physical Sciences Transmission Electron Microscopy Core Facility (RRID:SCR_028489) Copy
https://mcw.ilab.agilent.com/service_center/show_external/4967/cvc_core
Microscopy core managed by Cardiovascular Research Center. Operates as a teach and train service for confocal, slide scanning and general widefield fluorescence imaging.
Proper citation: Medical College of Wisconsin Cardiovascular Research Center CVRC Microscopy Core Facility (RRID:SCR_028523) Copy
Core provides access to analytical cytometers and cell sorters for trained users and operator-assisted cell sorting by appointment during business hours. Assists with protocol and assay development, including sample preparation, selection of antibodies and fluorochromes, proper staining and compensation controls, and selection of appropriate buffers. Offers assistance with data analysis using FlowJo, FCS Express, DIVA and SpectroFlo software is also available by appointment.
Proper citation: Medical College of Wisconsin Children's Research Institute Flow Cytometry Core Facility (RRID:SCR_028480) Copy
https://medicine.llu.edu/research/core-facilities/advanced-imaging-and-microscopy-core
Core offers microscopy services. Provides three offline analysis systems with Intel Xeon-based processors. Two of these are custom-built Origin computers and the third is a Dell Precision computer. All analysis workstations have the most recent versions of the Fiji build of Image J and RStudio.
Proper citation: Loma Linda University School of Medicine Advanced Imaging and Microscopy Core Facility (RRID:SCR_028455) Copy
Core provides services in confocal microscopy (CLSM, including FRET, ion imaging, and colocalization), scanning electron microscopy (SEM, including ESEM for wet samples), SEM prep instrumentation (critical point dryer and sputter coater), epifluorescence microscopy and polarizing microscopy.
Proper citation: University of Wisconsin Madison Newcomb Imaging Center NIC Core Facility (RRID:SCR_028453) Copy
cGMP facility responsible for the bulk product manufacture, purification, and characterization of clinical-grade materials. Offers vialing of sterile investigational products such as peptides, proteins, carbohydrates, and adjuvants. Service also conducts lot release tests which are required for products release for preclinical and investigational use either in-house or with validated contract vendors.
Proper citation: Memorial Sloan Kettering Cancer Center MSKCC Clinical Grade Production Core Facility (RRID:SCR_028454) Copy
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