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https://unclineberger.org/ogr/

Cancer genomics project management and data sharing support facility.

Proper citation: University of North Carolina at Chapel Hill Lineberger Office of Genomics Research Core Facility (RRID:SCR_028317) Copy   

•   Source: SciCrunch Registry

https://cancer.mcw.edu/researchers-and-clinicians/shared-resources/biorepository-and-tissue-analytics-shared-resource

Facility provides access to human stem cells, 3D organoids, and other human-relevant disease models to support more predictive drug discovery, improved safety and toxicity assessment, and deeper mechanistic insight. Leveraging organoid and microphysiological platforms, the core enables next-generation therapeutics and clinical trial-in-a-dish approaches that advance biomedical innovation and precision medicine.

Proper citation: Medical College of Wisconsin Cancer Center Stem Cell and Organoid Core Facility (RRID:SCR_028315) Copy   

•   Source: SciCrunch Registry

https://www.cruk.cam.ac.uk/core-facilities/proteomics/

Core offers services for identification, quantification, and structural characterisation of proteins using next–generation mass spectrometry platforms. Uses mass spectrometry platforms that include Orbitrap Lumos, Ascend and Astral Zoom systems. Services include designing of experimental strategies, implementing and validating previously developed proteomic workflows to profile proteins from diverse biological samples, as well as developing methods and assays when required. Core focuses and specializes in using stable isotopic labelling strategies (Tandem Mass Tags) as well as label-free methods using different acquisition methods (DDA and DIA) for relative quantification of protein expression levels and enrichment within protein complexes. Develops and runs PRM (parallel reaction monitoring) assays for targeted quantification of defined panels of proteins.

Proper citation: Cancer Research UK Cambridge Institute Proteomic Core Facility (RRID:SCR_028276) Copy   

•   Source: SciCrunch Registry

https://research.utk.edu/oried/core-facilities/advanced-microscopy-and-imaging-center/

Multi-user, multi-disciplinary facility that provides microscopy and imaging services. It houses instrumentation for optical microscopy including laser scanning confocal microscopy and total internal reflection microscopy (TIRF), scanning as well as transmission electron microscopy, MALDI mass spectrometry imaging, and an X-ray MicroCT. Offers complete technical support, individual training and courses that cover both the practical applications and physical principles of microscopy. Provides consultations for development of microscopy projects for inclusion in grant proposals.

Proper citation: University of Tennessee KnoxvilleAdvanced Microscopy and Imaging Center AMIC Core Facility (RRID:SCR_028273) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/environmental-exposure-analytical-chemistry-laboratory

Facility for trace-level analysis of anthropogenic organic chemicals in environmental and biological specimens.Specializes in mass spectrometry based analysis, including targeted and nontargeted methods. Capable of quantifying nearly all the organic analytes monitored by the Centers for Disease Control and Prevention (CDC) in the National Health and Nutrition Examination Survey (NHANES) program. Commonly assayed targets include phthalates, bisphenols, per- and polyfluoroalkyl substances (PFAS), glyphosate, organophosphate flame retardants, organophosphate pesticides, and other compound classes at biologically and environmentally relevant concentrations. Our nontargeted analysis workflows are capable of detecting hundreds to thousands of chemical features in a single sample, enabling the identification of unknown organic compounds without a priori target selection.Laboratory operates as a shared resource within NYU Langone's Division of Advanced Research Technologies (DART), which is part of the Office of Science and Research (OSR). We provide precise chemical analysis to support studies on environmental exposures and their health impacts.

Proper citation: NYU Langone Health Environmental Exposure and Analytical Chemistry Laboratory Core Facility (RRID:SCR_028274) Copy   

•   Source: SciCrunch Registry

https://ycmd.yale.edu/

Full-service core facility specializing in high throughput assay development and screening of chemical and genomic probes.

Proper citation: Yale Center for Molecular Discovery YCMD Core Facility (RRID:SCR_028309) Copy   

•   Source: SciCrunch Registry

https://sites.northwestern.edu/mltof/about/

Core offers instrumentation for electrical/magnetic/optical characterization of thin film and semi-conductor materials and devices. Temperature range depending on technique is -1.8K to 400K.

Proper citation: Northwestern University Magnet Low Temperature and Optics Facility MLTOF Core Facility (RRID:SCR_028307) Copy   

•   Source: SciCrunch Registry

http://go.osu.edu/mbgc

Core provides integrated, end-to-end support for molecular biology and genomics research. Services include DNA/RNA extraction, sample quality control, genotyping, qPCR/ddPCR, and next-generation sequencing using Illumina and Oxford Nanopore platforms. In addition to laboratory services, MBGC offers consultation, experimental design guidance, troubleshooting, and training to support high-quality and reproducible research outcomes.

Proper citation: Ohio State University Molecular Biology and Genomics Core Facility (RRID:SCR_028289) Copy   

•   Source: SciCrunch Registry

https://www.utm.utoronto.ca/research-innovation/research-innovation-core

Core brings together UTM’s Growth Facilities, Imaging Facility, Life Sciences Facilities, and NMR Centre into a unified ecosystem that supports academic researchers with shared tools, expert support, and hands‑on training. Provided services include design of multi-scale experimental workflows,cross-platform training,coordinated sample preparation across scales,seamless facility operations,facilitation of data integration, and troubleshooting.

Proper citation: University of Toronto Research and Innovation Core Facility (RRID:SCR_028286) Copy   

•   Source: SciCrunch Registry

https://boku.ac.at/cf/bmosa

Core provides high throughput microbiology screening services and high-end mass spectrometry for diverse range of molecules.

Proper citation: BOKU University Bioactive Molecules Screening and Analysis BMOSA Core Facility (RRID:SCR_028285) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/advanced-tissue-imaging-shared-resource

Core offers streamlined, multiplexed tissue analysis services including tissue sectioning, staining, imaging, spatial RNA sequencing, analysis and interpretation of results.

Proper citation: Roswell Park Comprehensive Cancer Center Advanced Tissue Imaging Shared Resource ATISR Core Facility (RRID:SCR_028378) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/small-molecule-and-metabolite-core

Core focuses on quantitative bioanalytical assay development, validation and implementation for drugs, metabolites and biomarkers in blood, serum, plasma, urine, ultrafiltrate and microdialysate utilizing mass spectrometry techniques.

Proper citation: Children's Hospital of Philadelphia CHOP Small Molecule and Metabolite Core Facility (RRID:SCR_028411) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/qualitative-research-core

Core supports all Children's Hospital of Philadelphia Research Institute personnel and faculty who are interested in utilizing qualitative methods. Provides research support across a broad range of settings, including in-hospital clinical research, primary care, public health, and community-based settings. Services include free introductory videos, yearly seminars, customized project workshops, and hands-on project support and grantmaking.

Proper citation: Children's Hospital of Philadelphia CHOP Qualitative Research Core Facility (RRID:SCR_028412) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/biorepository-laboratory-services

Core is comprehensive data and biospecimen bank (malignant and normal tissue and their derivatives, blood and bone marrow) for research along with a range of services that accompany biospecimens. Facilitates access to human tissue, blood and bone marrow for investigators with Institutional Review Board (IRB) approved protocols emphasizing translational research. Helps investigators to establish Biospecimen and Data Research (BDR) protocols and supports the submission of grants by providing feasibility analysis, cost estimates and letters of support.

Proper citation: Roswell Park Comprehensive Cancer Center Biorepository and Laboratory Services Shared Resource BLS Core Facility (RRID:SCR_028376) Copy   

•   Source: SciCrunch Registry

https://biotech.rpi.edu/core-facilities/proteomics

Facility provides mass spectrometry-based analytical support.Houses multiple mass spectrometry platforms with complementary ionization capabilities, including EI, APCI, ESI, and MALDI, enabling qualitative and quantitative analysis of diverse sample types across a range of volatility, polarity, and molecular weight. Several systems are coupled with chromatographic separation platforms, allowing complex mixtures to be separated prior to mass spectrometric analysis. Supports research in areas including proteomics, small-molecule analysis, carbohydrate and glycosaminoglycan-related analysis, metabolomics-oriented method development, and drug-discovery-related projects.Particular strength of the Core is the analysis of complex biomolecules, including proteins, peptides, carbohydrates, and heparin/glycosaminoglycan-related samples. The Core works closely with investigators to evaluate feasibility, develop appropriate workflows, and interpret mass spectrometry data in the context of each project.

Proper citation: Rensselaer Polytechnic Institute RPI-Proteomics Core Facility (RRID:SCR_028377) Copy   

•   Source: SciCrunch Registry

https://chop.ilab.agilent.com/sc/5558/chop-engineered-cell-therapy-core/?tab=about

Core provides services and expertise to advance chimeric antigen receptor (CAR) T or other cell therapy research.Services include guidance in the design, construction, and selection of CARs and other cell therapies against a multitude of targets and diseases. Core offers small-scale lentivirus production and small-scale T cell transduction and expansion for experimental purposes.

Proper citation: Children's Hospital of Philadelphia CHOP Engineered Cell Therapy Core Facility (RRID:SCR_028415) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/biostatistics-statistical-genomics

Core offers services in design, oversight, implementation, analysis, publication, and reporting of scientific studies including articulating study objectives and hypotheses, grant writing, conceiving appropriate cost-effective designs and models for achievement of study objectives, monitoring interim and final analyses, and co-authoring abstracts and manuscripts.

Proper citation: Roswell Park Comprehensive Cancer Center Biostatistics and Statistical Genomics Shared Resource BSGSR Core Facility (RRID:SCR_028371) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/gmp

Core provides clean rooms, cell therapy equipment, manufacturing know-how, capabilities and comprehensive suite of quality assurance and control procedures.

Proper citation: Roswell Park Comprehensive Cancer Center GMP Engineering and Cell Manufacturing Core Facility (RRID:SCR_028373) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/chop-microbiome-center

Core is sequencing and analytical resource of the PennCHOP Microbiome Program, providing end-to-end solutions for microbiome research. Sequencing lab offers expertise in next-generation DNA sequencing for microbiome studies, working with customers to provide optimized workflows and protocols customized for each study. Provides expertise in bioinformatics and statistical analysis of microbiome data. Develops an analytical plan specific to your project and can integrate microbiome data with other data sources, such as metabolomics or dietary intake information.

Proper citation: Children's Hospital of Philadelphia CHOP Microbiome Center Core Facility (RRID:SCR_028408) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/comparative-oncology

Core offers services for preclinical models including barrier facilities with fully automated environmental controls for the housing of research models. Specialized husbandry with trained staff who perform all manipulations inside Biosafety cabinets for maintenance of a pathogen-free environment for models held in micro isolation (MI) housing systems. In addition to housing pre-clinical models in state-of-the-art facilities, COSR provides Specialized Surgical Services and procedural training, consultation in experimental design, irradiation services, in-house hematological testing, genotyping services, design and conduct of pre-clinical toxicological studies.

Proper citation: Roswell Park Comprehensive Cancer Center Comparative Oncology Shared Resource COSR Core Facility (RRID:SCR_028389) Copy   

•   Source: SciCrunch Registry