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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
J-Express
 
Resource Report
Resource Website
50+ mentions
J-Express (RRID:SCR_003609) J-Express software resource Gene expression analysis software using Java. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is parent organization of: Mini Analysis Guide for Microarrays
PMID:11301307 Acknowledgement requested biotools:j-express, OMICS_00767 https://bio.tools/j-express SCR_003609 J-Express: Gene expression analysis software 2026-09-19 12:50:23 87
bioRxiv
 
Resource Report
Resource Website
1000+ mentions
bioRxiv (RRID:SCR_003933) bioRxiv community building portal, data or information resource, database, portal A free archive and distribution service for unpublished preprints in the life sciences allowing authors to make their findings immediately available to the scientific community and receive feedback on draft manuscripts before they are submitted to journals. An article may be posted prior to, or concurrently with, submission to a journal but should not be posted if it has already been published. Once an article is published in a journal, bioRxiv will update the preprint with a link to the published version. preprint, life science, bio.tools, FASEB list is used by: PrePubMed
is listed by: LabWorm
is listed by: bio.tools
is listed by: Debian
is related to: Overleaf
has parent organization: Cold Spring Harbor Laboratory
Free, Acknowledgement requested, The community can contribute to this resource biotools:bioRxiv, nlx_158302 https://bio.tools/bioRxiv SCR_003933 bioRxiv - the preprint server for biology 2026-09-19 12:50:29 1368
Git
 
Resource Report
Resource Website
50+ mentions
Git (RRID:SCR_003932) software application, software development tool, software resource, version source control system A free and open source distributed version control system designed to handle everything from small to very large projects with speed and efficiency. Git is easy to learn and has a tiny footprint with lightning fast performance. It outclasses SCM tools like Subversion, CVS, Perforce, and ClearCase with features like cheap local branching, convenient staging areas, and multiple workflows. version control, distributed, bio.tools is used by: DataLad
is used by: G-Node Data Infrastructure Services
is listed by: bio.tools
is listed by: Debian
works with: git-annex
GNU General Public License, v2 nlx_158301, biotools:Git https://bio.tools/Git SCR_003932 2026-09-19 12:50:29 73
Quantitative Enrichment of Sequence Tags
 
Resource Report
Resource Website
10+ mentions
Quantitative Enrichment of Sequence Tags (RRID:SCR_004065) QuEST software resource A Kernel Density Estimator-based package for analysis of massively parallel sequencing data from chromatin immunoprecipitation (ChIP-seq) experiments. genome-wide, transcription factor binding site, chip-seq, transcription factor, binding site, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Stanford University; Stanford; California
PMID:19160518 OMICS_00458, biotools:quest https://bio.tools/quest SCR_004065 Quantitative Enrichment of Sequence Tags: QuEST 2026-09-19 12:50:32 49
Pash 3.0
 
Resource Report
Resource Website
1+ mentions
Pash 3.0 (RRID:SCR_004078) Pash 3.0 software resource Performs sequence comparison and read mapping and can be employed as a module within diverse configurable analysis pipelines, including ChIP-Seq and methylome mapping by whole-genome bisulfite sequencing. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:21092284 biotools:pash, OMICS_00586 https://bio.tools/pash SCR_004078 2026-09-19 12:50:32 1
EpiGRAPH
 
Resource Report
Resource Website
10+ mentions
EpiGRAPH (RRID:SCR_004326) EpiGRAPH software resource A software for genome and epigenome analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00633, biotools:epigraph https://bio.tools/epigraph SCR_004326 2026-09-19 12:50:36 18
PubChem
 
Resource Report
Resource Website
10000+ mentions
PubChem (RRID:SCR_004284) data or information resource, data repository, database, service resource, storage service resource Collection of information about chemical structures and biological properties of small molecules and siRNA reagents hosted by the National Center for Biotechnology Information (NCBI). collection, information, data, chemical, structure, biological, property, small, molecule, siRNA reagent, bio.tools uses: ChEMBL
is used by: NIF Data Federation
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is used by: GEROprotectors
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIH Data Sharing Repositories
is listed by: bio.tools
is listed by: Debian
is related to: NCBI Structure
is related to: Molecular Libraries Program
is related to: NIH Data Sharing Repositories
is related to: PubChem BioAssay
has parent organization: NCBI
is parent organization of: PubChem Substance
works with: MiMeDB
NLM PMID:21418625
PMID:21272340
PMID:20970519
PMID:20298522
PMID:19825798
Free, Freely Available biotools:pubchem, nlx_42691, nlx_29861, r3d100010538, OMICS_01587 https://bio.tools/pubchem, https://doi.org/10.17616/R3GW37 SCR_004284 2026-09-19 12:50:35 15598
InsertionMapper
 
Resource Report
Resource Website
InsertionMapper (RRID:SCR_004163) InsertionMapper software resource A pipeline tool for the identification of targeted sequences from multidimensional high throughput sequencing data. It consists of four independently working modules: Data Preprocessing, Database Modeling, Dimension Deconvolution and Element Mapping. This pipeline tool is applicable to scenarios requiring analysis of the tremendous output of short reads produced in NGS sequencing experiments of targeted genome sequences. high throughput sequencing, dna sequence, next generation sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Montclair State University; New Jersey; USA
PMID:24090499 Acknowledgement requested, GNU General Public License OMICS_01547, biotools:insertionmapper https://bio.tools/insertionmapper SCR_004163 2026-09-19 12:50:34 0
bcbio-nextgen
 
Resource Report
Resource Website
100+ mentions
bcbio-nextgen (RRID:SCR_004316) bcbio-nextgen software resource A python toolkit providing best-practice pipelines for fully automated high throughput sequencing analysis. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:bcbio-nextgen, OMICS_01121, BioTools:bcbio-nextgen https://github.com/chapmanb/bcbb/blob/master/nextgen/README.md, https://bio.tools/bcbio-nextgen, https://bio.tools/bcbio-nextgen SCR_004316 2026-09-19 12:50:36 165
PDBe - Protein Data Bank in Europe
 
Resource Report
Resource Website
50+ mentions
PDBe - Protein Data Bank in Europe (RRID:SCR_004312) PDBe data or information resource, data repository, database, service resource, storage service resource The European resource for the collection, organization and dissemination of data on biological macromolecular structures. In collaboration with the other worldwide Protein Data Bank (wwPDB) partners - the Research Collaboratory for Structural Bioinformatics (RCSB) and BioMagResBank (BMRB) in the USA and the Protein Data Bank of Japan (PDBj) - they work to collate, maintain and provide access to the global repository of macromolecular structure data. The main objectives of the work at PDBe are: * to provide an integrated resource of high-quality macromolecular structures and related data and make it available to the biomedical community via intuitive user interfaces. * to maintain in-house expertise in all the major structure-determination techniques (X-ray, NMR and EM) in order to stay abreast of technical and methodological developments in these fields, and to work with the community on issues of mutual interest (such as data representation, harvesting, formats and standards, or validation of structural data). * to provide high-quality deposition and annotation facilities for structural data as one of the wwPDB deposition sites. Several sophisticated tools are also available for the structural analysis of macromolecules. x-ray, nmr, cryo-em, hybrid method, dna, protein, rna, sugar, ligand, virus, compound, fold, enzyme, 3d spatial image, structure, macromolecule, protein-protein interaction, gold standard, bio.tools is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: DNA DataBank of Japan (DDBJ)
is related to: EMDataResource.org
is related to: Worldwide Protein Data Bank (wwPDB)
is related to: Biological Magnetic Resonance Data Bank (BMRB)
is related to: DNA DataBank of Japan (DDBJ)
is related to: Worldwide Protein Data Bank (wwPDB)
is related to: PDBj - Protein Data Bank Japan
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: European Bioinformatics Institute
is parent organization of: Electron Microscopy Data Bank at PDBe (MSD-EBI)
works with: MOLEonline
European Molecular Biology Laboratory; Heidelberg; Germany ;
Wellcome Trust ;
BBSRC ;
NIH ;
European Union ;
MRC ;
CCP4
PMID:21045060
PMID:21460450
PMID:19858099
r3d100012791, biotools:pdbe, nlx_32372 https://bio.tools/pdbe, https://doi.org/10.17616/R3J226 SCR_004312 Protein DataBank Europe, Protein DataBank in Europe, PDBe, Protein Data Bank in Europe, Protein Data Bank Europe, Macromolecular Structure Database 2026-09-19 12:50:35 55
NeuroMatic
 
Resource Report
Resource Website
100+ mentions
NeuroMatic (RRID:SCR_004186) data analysis software, data processing software, software application, software resource NeuroMatic is a collection of Igor Pro functions for analyzing electrophysiological data. By allowing users to organize their data into Sets and Groups, NeuroMatic makes it relatively easy to compute transformations and statistical analyses on their data, including scaling, alignment averaging, baseline subtraction, spike detection, stationarity analysis, rise-time computations, etc. Being open source and modular designed, NeuroMatic also allows users to develop their own analysis functions that can be easily incorporated into NeuroMatic's framework. Note, if you have reached this page in search of a freeware tool for neuronal reconstructions, you are more likely to be interested in Neuromantic, a software package that sounds like NeuroMatic, but is not quite the same. Features of NeuroMatic Include * Sorting, Scaling, Averaging, Interpolation * Max / Min / Mean / Level / Rise Time / FWHM / Slope Measurements * Stability / Stationarity Analysis * Event Detection * Waveform Template Matching * Spike Raster Plots * Interspike-Interval and Peri-Stimulus Time (PST) Histograms * Compact Easy-to-Use Interface * Modular design as a basis for your own procedures * Extra space for your own buttons and controls * Import functions for Axograph and Pclamp data * Automatic macro generation for batch processing Supporting Agencies: MRC, Wellcome Trust Spike, Event, Fit, NClamp, Acquisition, spike train, EPSP, IPSP, IPSC, EPSC epsc, epsp, event, fit, acquisition, data management, ipsc, ipsp, nclamp, software, spike, spike train, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University College London; London; United Kingdom
PMID:29670519 nif-0000-00073, biotools:neuromatic https://bio.tools/neuromatic SCR_004186 NeuroMatic 2026-09-19 12:50:34 315
TagDust
 
Resource Report
Resource Website
50+ mentions
TagDust (RRID:SCR_004175) TagDust software resource A program to eliminate artifactual reads from next-generation sequencing data sets. unix/linux, bio.tools, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:19737799 biotools:tagdust, OMICS_01095, biotools:nexalign https://bio.tools/tagdust, https://bio.tools/nexalign SCR_004175 2026-09-19 12:50:34 55
RatMine
 
Resource Report
Resource Website
1+ mentions
RatMine (RRID:SCR_004190) analysis service resource, data access protocol, data analysis service, data or information resource, database, production service resource, service resource, software resource, web service RatMine integrates data from RGD, UniProtKB, NCBI, KEGG and other sources to form a web-based data warehouse and tool set tailored for rat based data research. Search RatMine by entering names, identifiers, or keywords for genes, proteins, pathways, papers, etc. Additionally, we support programmatic access to our data through Application Programming Interface - choose from Perl or Java API. RatMine is a data warehouse that integrates many diverse biological data sets. The main focus is R. norvegicus genomics and proteomics. By integrating such data into one place it is possible to construct queries across domains of biological knowledge. The RatMine user interface is designed to go beyond simply looking up an identifier and viewing a report page. Some of the features include: * Quick Search is available just like on other sites, type in an identifier to see a report page. * Template queries are ''canned'' queries that provide a simple form to perform a specific task. You can create your own templates if you log in. * Lists lets you operate on whole lists of data at once. You can upload lists or save them from results tables. We also create useful public lists for everyone to use. * MyMine lets you create an account to save your own queries, bags and templates, as well as marking public templates as favorites. disease, interaction, proteins, single nucleotide, gene ontology, mammalian phenotype, publication, genomics, pathway, quantitative trait loci, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Medical College of Wisconsin; Wisconsin; USA
biotools:RatMine, nlx_21635 https://bio.tools/RatMine SCR_004190 2026-09-19 12:50:34 5
Artemis: Genome Browser and Annotation Tool
 
Resource Report
Resource Website
100+ mentions
Artemis: Genome Browser and Annotation Tool (RRID:SCR_004267) Artemis software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Free genome browser and annotation tool that allows visualization of sequence features, next generation data and the results of analyses within the context of the sequence, and also its six-frame translation. Artemis is free software and is distributed under the terms of the GNU General Public License. Artemis is written in Java, and is available for UNIX, Macintosh and Windows systems. It can read EMBL and GENBANK database entries or sequence in FASTA, indexed FASTA or raw format. Other sequence features can be in EMBL, GENBANK or GFF format. training tool, genome browser, gene annotation, java, bio.tools is listed by: OMICtools
is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is related to: DNAPlotter
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
works with: Alien-hunter
Wellcome Trust PMID:11120685
DOI:10.1093/bioinformatics/btr703
THIS RESOURCE IS NO LONGER IN SERVICE nlx_28554, OMICS_00903, biotools:artemis https://bio.tools/artemis, https://sources.debian.org/src/art-nextgen-simulation-tools/ SCR_004267 2026-09-19 12:50:35 422
DER Finder
 
Resource Report
Resource Website
1+ mentions
DER Finder (RRID:SCR_004250) DER Finder data processing software, software application, software library, software resource, software toolkit R package for differential expression analysis of RNA-seq data. differential expression, rna-seq, false discovery rate, genomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24398039 Free, Public biotools:derfinder, OMICS_02208 https://bio.tools/derfinder SCR_004250 derfinder 2026-09-19 12:50:35 5
959 Nematode Genomes
 
Resource Report
Resource Website
1+ mentions
959 Nematode Genomes (RRID:SCR_006068) NematodeGenomes data or information resource, narrative resource, wiki A collaborative wiki that collates information on completed, ongoing and planned genome and transcriptome sequencing projects on species from phylum Nematoda. The intention is to encourage genome sequencing across the diversity of the phylum Nematoda. Wiki includes: * Published complete nematode genomes: A dynamically generated table of all species for which the genome is published. * Nematode species with genomes in progress: A dynamically generated table of all species for which a genome project is underway. Users may add species to the list * Proposed nematode genome projects: To propose a species for genome sequencing, edit its species page, and set the genome project status to proposed. * BLAST server: Search a number of the nematode-genomes-in-progress with genes of your choice. Currently there are 12 draft genomes available... * Genomes with Data available: Genomes with data available for download. Users may add more data URLs to strain pages or update the URLs. nematode, genome, genome sequencing, transcriptome sequencing, blast, genomics, sequencing, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: nematodes.org
has parent organization: University of Edinburgh; Scotland; United Kingdom
NERC PMID:22058131 nlx_151473, biotools:959_nematode_genomes https://bio.tools/959_nematode_genomes SCR_006068 NematodeGenomes 2026-09-19 12:51:04 2
MMMDB - Mouse Multiple tissue Metabolome DataBase
 
Resource Report
Resource Website
1+ mentions
MMMDB - Mouse Multiple tissue Metabolome DataBase (RRID:SCR_006064) MMMDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource MMMDB, Mouse Multiple tissue Metabolome DataBase, is a freely available metabolomic database containing a collection of metabolites measured from multiple tissues from single mice. The datases are collected using a single instrument and not integrated from literatures, which is useful for capturing the holistic overview of large metabolomic pathway. Currently data from cerabra, cerebella, thymus, spleen, lung, liver, kidney, heart, pancreas, testis, and plasma are provided. Non-targeted analyses were performed by capillary electropherograms time-of-flight mass spectrometry (CE-TOFMS) and, therefore, both identified metabolites and unknown (without matched standard) peaks were uploaded to this database. Not only quantified concentration but also processed raw data such as electropherogram, mass spectrometry, and annotation (such as isotope and fragment) are provided. metabolite, metabolome, cerabra, cerebella, thymus, spleen, lung, liver, kidney, heart, pancreas, testis, plasma, metabolomic pathway, capillary electropherograms time-of-flight mass spectrometry, electropherogram, mass spectrometry, annotation, isotope, fragment, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:22139941 Free nlx_151467, biotools:mmmdb https://bio.tools/mmmdb SCR_006064 Mouse Multiple tissue Metabolome DataBase 2026-09-19 12:51:04 1
InterEvol database
 
Resource Report
Resource Website
10+ mentions
InterEvol database (RRID:SCR_006054) InterEvol analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software resource InterEvol database is designed for the analysis of co-evolution events at the interface of known structures of hetero- and homo-oligomers. The database can be search and analyzed through 3 interconnected levels of analysis: * From a Keyword or the PDB entry of a complex, you can browse: ** structural homologs for every chain in other complexes ** structural interologs for every interface ** retrieve pre-computed sequence alignments in diverse species * From 1 or 2 sequences of interacting partners: ** build 2 multiple sequence alignments with the same species ordered in each ** query the InterEvol database with alignments using profile-profile comparison method * Visualize structure vs sequence alignment at the complex interface ** A dedicated Pymol plugin is provided ** Alignment views in Pymol are interactively restricted to the residues selected at the interface structure, evolution, protein complex, interface, protein complex, sequence alignment, plug in, protein structure, visualization, pymol plugin, structural homolog, structural interolog, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: CEA; Gif sur Yvette; France
Commissariat a lEnergie Atomique ;
ANR HPGenVar
PMID:22053089 Free and open to all users - no login requirement nlx_151453, biotools:interevol https://bio.tools/interevol SCR_006054 2026-09-19 12:51:04 10
RAxML
 
Resource Report
Resource Website
10000+ mentions
RAxML (RRID:SCR_006086) RAxML data analysis software, data processing software, software application, software resource Software program for phylogenetic analyses of large datasets under maximum likelihood. phylogeny, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: RAxML Next Generation
works with: PAML
PMID:24451623
PMID:16928733
PMID:15608047
DOI:10.1093/bioinformatics/btu033
GNU General Public License biotools:raxml, OMICS_02242 https://bio.tools/raxml, https://sources.debian.org/src/raxml/ SCR_006086 Randomized Axelerated Maximum Likelihood 2026-09-19 12:51:04 12997
OGEE - Online GEne Essentiality database
 
Resource Report
Resource Website
1+ mentions
OGEE - Online GEne Essentiality database (RRID:SCR_006080) OGEE, OGEEdb analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Online GEne Essentiality database containing genes that were tested experimentally for essentiality and their features; it also provides a set of tools to systematically explore and analyze these data. The main purpose of this project is to better understand gene essentiality by facilitating the comparisons of the differences and similarities between essential and non-essential genes. This is achieved by collecting not only experimentally tested essential and non-essential genes, but also associated gene features such as expression profiles, duplication status, conservation across species, evolutionary origins and involvement in embryonic development. We focus on large-scale experiments and complement our data with text-mining results. Genes are organized into data sets according to their sources. Genes with variable essentiality status across data sets are tagged as conditionally essential, highlighting the complex interplay between gene functions and environments. Linked tools allow the user to compare gene essentiality among different gene groups, or compare features of essential genes to non-essential genes, and visualize the results. Why is it different from existing databases? * we included both essential and non-essential genes so that we could better understand the gene essentiality by comparing the similarities and differences between the two gene sets; * we compiled a list of features for each gene, including whether they are duplicates or involved in development, the number of other homologous genes in the same genome, as well as their earliest expression stages during development. These features are keys to understand the essentiality of genes; * we also provide a set of tools to explore our data and visualize the results. For example, users can simply divide genes into two groups according to whether they are duplicates, calculate the proportion of essential genes (PE%) in each group and then visualize the results in a bar plot; or they can classify genes into multiple groups according to their earliest expression stages during evolution, compare the essentiality of genes that were expressed earlier with those were latter, and plot the results in a line chart. genome-wide association study, essentiality, gene, essential gene, non-essential gene, growth, expression profile, duplication status, conservation, evolutionary origin, embryonic development, text-mining, gene function, environment, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
BMBF 0315450C PMID:22075992 Free nlx_151488, biotools:ogee https://bio.tools/ogee SCR_006080 Online GEne Essentiality database 2026-09-19 12:51:04 2

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