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https://sites.google.com/fieldmuseum.org/research/laboratories/core-laboratories/sem
Interdepartmental core facility for scanning electron microscope imaging and elemental analysis of objects. Provides Hitachi SU7000 field emission scanning electron microscope, an Oxford Ultim Max 170 infinity EDS detector with BEX (backscatter electron and X-ray imaging detector), a Leica EM Ace600 sputter coater and a Hitachi IM4000II ion milling system.
Proper citation: Field Museum of Natural History Scanning Electron Microscopy Laboratory Core Facility (RRID:SCR_028394) Copy
https://institutducerveau.org/plateforme-dexploration-preclinique-phenoparc
Core provides infrastructure (A1 and A2 zoned) and technical expertise for standardized husbandry, breeding, experimental use of rodent and health monitoring (SPF and SOPF zones) in compliance with regulatory and ethical guidelines. The platform offers technical services such as Surgery on brain and spinal cord, Behavioral tests (anxiety, depression, cognition, motor/locomotor and visual parameters, spontaneous activity, USV recording etc… ), embryo transfer. Training and technical support are available for rodent handling, experimental design, and data reproducibility.
Proper citation: Paris Brain Institute PhenoICMice Core Facility (RRID:SCR_028531) Copy
https://nyulangone.sharepoint.com/sites/pophealth-data-hub
Core to improve access, efficiency, and support for research teams working with a wide range of data sources to study and address population health issues. Part of data ecosystem of research data hubs and related services at NYULH. Our goal is to help Population Health PIs and Analysts solve their administrative and analysis issues. This includes data acquisition, storage, cleaning, analysis, and dissemination.
Proper citation: New York University Langone Health NYULH Population Health Data Hub Core Facility (RRID:SCR_028492) Copy
Core provides services in design, construction, and production of custom research grade viral vectors for biomedical research including Adeno-associated viral (AAV) vectors, Retroviral vectors (MLV-based), Lentiviral vectors (LV), Virus-Like Particles (VLPs / Nanoblades).
Proper citation: Catholic University of Leuven Viral Vector Core Facility (RRID:SCR_028527) Copy
https://research.ncsu.edu/metric/
Molecular Education, Technology and Research Innovation Center (METRIC) is an NC State University-wide Shared Core Research Facility administered by the Office of Research and Innovation. We provide internal and external researchers with access to instrumentation and technical expertise across three primary analytical platforms: Mass Spectrometry: Supports qualitative and quantitative analyses, including high-resolution accurate mass (HRAM) measurements, proteomics, metabolomics, and small molecule analysis. Magnetic Resonance (NMR & EPR): Provides structural and dynamic characterization of molecules in solution. Capabilities include multi-nuclear solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy for studying paramagnetic species, transition metal complexes, and free radicals. X-Ray Diffraction: Offers atomic-level structural determination. The facility is equipped for single-crystal X-ray diffraction of both small molecules (including absolute configuration determination) and macromolecules/proteins.
Proper citation: North Carolina State University NCSU METRIC Core Facility (RRID:SCR_028548) Copy
Core provides specialized imaging services for primarily biological research, with additional applications for materials chemistry, forensic science, and engineering technology. Available instrumentation includes various light microscopes, a laser-scanning confocal, scanning and transmission electron microscopes, and X-ray imaging.
Proper citation: Sam Houston State University SHSU-Microscopy Core Facility (RRID:SCR_028477) Copy
Core for high resolution imaging and structural analysis of biological specimens, soft matter, and nanomaterials. Used to process samples from solution or powder, allowing researchers to visualize internal structures down to the subnanometer scale. It is critically important that the samples are non-magnetic.
Proper citation: University College London Mathematical and Physical Sciences Transmission Electron Microscopy Core Facility (RRID:SCR_028489) Copy
https://mcw.ilab.agilent.com/service_center/show_external/4967/cvc_core
Microscopy core managed by Cardiovascular Research Center. Operates as a teach and train service for confocal, slide scanning and general widefield fluorescence imaging.
Proper citation: Medical College of Wisconsin Cardiovascular Research Center CVRC Microscopy Core Facility (RRID:SCR_028523) Copy
Core provides access to analytical cytometers and cell sorters for trained users and operator-assisted cell sorting by appointment during business hours. Assists with protocol and assay development, including sample preparation, selection of antibodies and fluorochromes, proper staining and compensation controls, and selection of appropriate buffers. Offers assistance with data analysis using FlowJo, FCS Express, DIVA and SpectroFlo software is also available by appointment.
Proper citation: Medical College of Wisconsin Children's Research Institute Flow Cytometry Core Facility (RRID:SCR_028480) Copy
https://medicine.llu.edu/research/core-facilities/advanced-imaging-and-microscopy-core
Core offers microscopy services. Provides three offline analysis systems with Intel Xeon-based processors. Two of these are custom-built Origin computers and the third is a Dell Precision computer. All analysis workstations have the most recent versions of the Fiji build of Image J and RStudio.
Proper citation: Loma Linda University School of Medicine Advanced Imaging and Microscopy Core Facility (RRID:SCR_028455) Copy
https://rtsf.natsci.msu.edu/proteomics/index.aspx
Core provides mass spectrometry resources and expertise to assist researchers in the identification and characterization of proteins and peptides. Experiments from simple protein discovery to complex differential proteome profiling, post-translational modification mapping and protein/peptide quantification can be performed using our instrumentation and software.
Proper citation: Michigan State University Proteomics Core Facility (RRID:SCR_028467) Copy
https://cores.research.utdallas.edu/imaging-and-histology-core/
Core Facility is located in the Natural Science and Engineering Research Laboratory. Provides support for basic and translational research in biological and interdisciplinary sciences through its instruments. Core has advanced imaging systems including confocal microscopes, high-throughput slide scanner, multiphoton intravital microscope, electron microscopes, and various other optical instruments. Houses workstations equipped with advanced image analysis software such as Imaris and cellSens Dimension. Provides support for processing and embedding of tissue samples, sectioning and slide preparation, and cell culture.
Proper citation: University of Texas at Dallas UTD Imaging and Histology Core Facility (RRID:SCR_028553) Copy
https://elektronenmikroskopie.charite.de/
Core provides electron microscopy services including Sample preparation from tissues, cell culture, cell suspension; Sample preparation for materials science; Preparation of semi-thin sections; Preparation of ultrathin sections for classical TEM , REM and serial reconstruction;Contrast methods for TEM samples, SEM samples, negative contrast, coating methods for SEM; Classical TEM and REM; Immunogold technique;Tokuyasu freeze-cutting technique; Cryo-substitution; Cryo-electron microscopy; Electron tomography; 3D array tomography; SBF-SEM; Image documentation and digital processing; Technical-preparative adjustments; Provision of infrastructure (sample preparation, electron microscopes, individual user training); Creating image documentation and evaluations; Image processing techniques and quantitative evaluation techniques (Image J, Fiji/TrakEM2, IMOD/3Dmod, Amira 5, ZEN Connect, etc.); Publication consulting.
Proper citation: Charité Berlin University of Medicine Electron Microscopy Core Facility (RRID:SCR_028563) Copy
https://www.crukscotlandinstitute.ac.uk/about/use-of-animals-in-our-research.html
Core facility provides technical services including transgenic breeding, chemical carcinogenesis treatment, tumourigenicity studies in nude mice and quarantine facilities to allow the import of animals from both Europe and other countries.
Proper citation: Cancer Research UK Scotland Institute Biological Services Core Facility (RRID:SCR_028654) Copy
https://web.uri.edu/riinbre/core-facility/
Core offers research instrumentation for hands-on use to researchers. Provides molecular biology, analytical, and imaging instruments to serve RI’s biomedical scientists totaling 3800 sq. ft. in the URI College of Pharmacy building.
Proper citation: University of Rhode Island RI-INBRE Centralized Research Core Facility (RRID:SCR_028658) Copy
Core provides Next Generation Sequencing (NGS) expertise and services including nucleic acid sample extraction, quantification, RT-qPCR and Quality Control (QC), experimental design, advanced data analysis.
Proper citation: RWTH Aachen University Genomics Facility of the Interdisciplinary Center for Clinical Research IZKF Core Facility (RRID:SCR_028662) Copy
https://www.medizin.rwth-aachen.de/go/id/pupf
Proteomics Facility is the centralized service unit of the Medical Faculty of RWTH Aachen University for the analysis of proteome samples. Offers sample preparation and mass spectrometric analysis, as well as bioinformatic processing of raw data (identification and quantification) of peptides and proteins, along with functional bioinformatic analysis of the resulting datasets.
Proper citation: RWTH Aachen University Proteomics Facility of the Interdisciplinary Center for Clinical Research IZKF Core Facility (RRID:SCR_028663) Copy
Core supports researchers in the use of modern light microscopy systems. Provides advanced optical imaging equipment, technical expertise, and hands-on training for biomedical and clinical research projects. Microscope platforms include confocal and multiphoton microscopy for imaging fluorescently labeled structures to enable the investigation and characterization of cells, tissues, organisms, and biomaterials with high spatial and temporal resolution.
Proper citation: RWTH Aachen University Light Microscopy Facility of the Interdisciplinary Center for Clinical Research IZKF Core Facility (RRID:SCR_028667) Copy
https://www.cruk.cam.ac.uk/core-facilities/pre-clinical-genome-editing/
Core facility provides genome editing services in vitro and in vivo for translational cancer research. Services span functional genomics (CRISPR screens across cells, organoids and patient-derived xenograft models, integrated with single-cell RNA sequencing), transgenics (embryo manipulation, pronuclear injection, electroporation, cryopreservation, and import/export of genetically modified models), and multimodal pre-clinical trials run through a dedicated Small Animal Hospital using genetically engineered, xenograft and orthotopic models. Offers experimental design consultation to match editing technologies to each research question.
Proper citation: Cancer Research UK Cambridge Institute Pre-Clinical Genome Editing Core Facility (RRID:SCR_028661) Copy
https://www.umt.edu/genomics-lab/default.php
Core is multi-user and service laboratory that offers comprehensive genetic and genomic services. Provides expert consultation, grant application support, training, and both standard and customized sequencing library preparation. Collaborates on genomics, transcriptomics and epigenomics projects.
Proper citation: University of Montana Genomics Core Facility (RRID:SCR_028659) Copy
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