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https://github.com/sccn/labstreaminglayer

System for unified collection of measurement time series in research experiments that handles networking, time synchronization, near real time access as well as optionally centralized collection, viewing and disk recording of data. System for synchronizing streaming data for live analysis or recording.

Proper citation: Lab Streaming Layer (RRID:SCR_017631) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000134-a517-1426-bf4c-ca4080000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core for bioinformatics consultation and software access. Laboratory of Molecular Computations and Bioinformatics (LMCB) is a resource facility dedicated to the support of computational biomedical research at Howard University. Provides molecular modeling, molecular dynamics, bioinformatics, and computational quantum chemistry capabilities and support to a variety of research projects at Howard University.

Proper citation: Howard University Center for Computational Biology and Bioinformatics Core Facility (RRID:SCR_009864) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5e87-861a-55da-381e80000000

Core for data driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. Aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.

Proper citation: Harvard Bioinformatics Core at Joslin Diabetes Center (RRID:SCR_009827) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-358b-059e-550e-f59280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core provides intellectual guidance for quantitative aspects of the design and analysis of center studies and expertise in biostatistical methods, environmental risk assessment, Geographic Information System (GIS) , spatial statistics, molecular biology, bioinformatics and statistical genetics. Core runs a regular seminar series and often sponsors short courses on specialized topics of interest to the community.

Proper citation: Harvard School of Public Health Environmental Statistics and Bioinformatics Core Facility (RRID:SCR_009822) Copy   

•   Source: SciCrunch Registry

http://tuskegee.eagle-i.net/i/00000136-648c-c32f-ee37-018280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides services and training in computational biology, bioinformatics, experimental design and statistical analysis to the RCMI researchers and the biomedical research community at Tuskegee University.

Proper citation: Tuskegee University Computational Biology and Bioinformatics - Biomedical Information Management Services (RRID:SCR_010065) Copy   

•   Source: SciCrunch Registry

https://github.com/csitron/Amino_acid_composition_and_hydrophobicity_analysis

Software package to analyze amino acid content and hydrophobicity profile of given set of protein sequences in fasta file. Used for analysis of amino acid composition and hydrophobicity of test sequences from fasta files.

Proper citation: Amino_acid_composition_and_hydrophobicity_analysis (RRID:SCR_026281) Copy   

•   Source: SciCrunch Registry

https://www.thermofisher.com/order/catalog/product/A45727

Ion Torrent Genexus Integrated Sequencer is part of the Ion Torrent Genexus System. Instrument that can automate library construction, templating, and sequencing in single-instrument run.

Proper citation: Thermo Fisher: Ion Torrent Genexus Integrated Sequencer (RRID:SCR_026449) Copy   

•   Source: SciCrunch Registry

https://www.microscop.ru/uploads/Helios-NanoLab-600i-ds-web.pdf

Scanning Electron Microscope advanced DualBeam for ultra-high resolution imaging, analysis and fabrication at the nanoscale. Helios NanoLab 600i builds on the success of FEI’s winning DualBeam series offering advances in ion beam, electron beam, patterning and range of features to make milling, imaging, analysis and sample preparation down to nanoscale.

Proper citation: FEI: Helios Nanolab 600i DualBeam (RRID:SCR_027033) Copy   

•   Source: SciCrunch Registry

http://www.biotech.ufl.edu/cores/gene-expression-genotyping/

Core provides services and consultation on Single Cell RNA-Seq, RNA-Seq, 16s metagenomics and Affymetrix gene expression arrays. High-throughput RNA-seq libraries, 16s libraries and sequencing capture libraries can be done by using Agilent Bravo robot. QuantiGene RNA Assays measure up to 80 gene targets directly with degraded and cross-linked RNA in FFPE tissues and blood, with no RNA purification required.BioRad QX200 AutoDG Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules with greater precision and sensitivity than qPCR, sensitivity off ddPCR System can facilitate expanded analysis of single cells. Genotyping services include fragment analysis using AB3730, 96 capillary technology, development of microsatellite libraries using Illumina sequence data, and genotyping using mouse tails or ear punches.

Proper citation: University of Florida ICBR Gene Expression and Genotyping Core Facility (RRID:SCR_019145) Copy   

•   Source: SciCrunch Registry

http://cobre.pbrc.edu/cores/genomics/

Provides services which include Sanger and next-generation DNA sequencing,DNA fragment analysis,qualitative and quantitative analysis of DNA, protein, and RNA samples, quantitative PCR, microarray RNA labeling, hybridization, and scanning robotics,bioinformatics.Individual and small group training and consultation services are offered for sequence analysis, real-time PCR, next-generation sequencing and microarray analysis.

Proper citation: Louisiana State University Pennington Biomedical Research Center Genomics Core Facility (RRID:SCR_018675) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/umpc

UMass Metabolic Disease Research Center (MDRC), formerly the National Mouse Metabolic Phenotyping Center, is a core facility that performs standardized experiments using state-of-the-art equipment for the purpose of investigating transgenic mouse models of diabetes, obesity, and metabolic liver disease. Provides metabolic and functional characterization of mouse models of human diseases that are developed by academic and industry researchers in joint efforts to understand metabolic diseases and to identify new therapies.

Proper citation: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility (RRID:SCR_018672) Copy   

•   Source: SciCrunch Registry

http://cores.musc.edu/Core/MS

Core provides expertise, services, education, and instrumentation to enhance biomedical research through LC-MS/MS-based proteomics. Services are offered for protein identification; characterization of post-translational modifications; and quantitative proteomics to identify differentially expressed/degraded proteins, regulated sites of post-translational modification, protein-protein interactions, and protein targets of drugs identified in phenotypic screens. Analyses include sample preparation, LC-MS/MS, database searching, generation of reports, and assistance with data interpretation. Faculty and staff assist with experimental design and development/optimization of customized methodology for analysis of post-translationally modified peptides (e.g. phosphorylation and O-GlcNAc modification, N- and O-linked glycosylation, Cys modifications including S-glutathionylation, and glycation of Lys and Arg). Quantitative approaches including metabolic labeling (SILAC), isobaric tagging (iTRAQ/TMT), and label free proteomics (LFQ) are performed on Orbitrap Elite or Orbitrap Fusion Lumos Mass Spectrometers. Developes methodology to identify alterations in post-translational modifications that impact signal transduction, transcription, translation, and response to therapeutics with goal of enabling investigators to discover molecular mechanisms underlying disease progression and therapeutic response.

Proper citation: South Carolina Medical University Mass Spectrometry Core Facility (RRID:SCR_017959) Copy   

•   Source: SciCrunch Registry

https://fralinlifesci.vt.edu/core-services/mass-spectrometry-incubator.html

Facility supports Virginia Tech's research infrastructure as mass spectrometry analysis and education center. Provides training in sample preparation, instrument operation and data analysis, with strong emphasis on metadata and analytical requirements for publication of metabolomic and proteomic results.

Proper citation: Virginia Tech Mass Spectrometry Incubator Core Facility (RRID:SCR_017956) Copy   

•   Source: SciCrunch Registry

https://grcf.jhmi.edu/

Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.

Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/medicine/research/corefacilities/core-personnel/core-research-personnel---cell-imagine-centre.html

Cell Imaging Centre provides services and training for imaging and analysis of live or fixed cells and tissues.Image acquisition equipment and expert consultation for experimental design related to light and electron microscopy are offered, with full technical assistance, from sample processing through image analysis.

Proper citation: University of Alberta Faculty of Medicine and Dentistry Cell Imaging Centre Core Facility (RRID:SCR_019200) Copy   

•   Source: SciCrunch Registry

https://github.com/cobilab/altair

Software C toolkit for alignment free and spatial temporal analysis of multi-FASTA data. Used for entangling presence of multiple sequences from epidemic and pandemic events.

Proper citation: AltaiR (RRID:SCR_024752) Copy   

•   Source: SciCrunch Registry

https://pepatac.databio.org/en/latest/

Software standardized pipeline for ATAC-seq data analysis with serial alignments. Leverages unique features of ATAC-seq data to optimize for speed and accuracy, and provides several unique analytical approaches. Downstream analysis is simplified by standard definition format, modularity of components, and metadata APIs in R and Python. Restartable, fault-tolerant, and can be run on local hardware, using any cluster resource manager, or in provided Linux containers. We also emphasize the advantage of aligning to the mitochondrial genome serially, which improves alignment and quality control metrics. Includes quality control plots, summary statistics, and variety of data formats.

Proper citation: PEPATAC (RRID:SCR_024758) Copy   

•   Source: SciCrunch Registry

http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_MedicinalChemistry.aspx

Core facility that provides general synthetic and medicinal chemistry resources and expertise to the biomedical research community. Services include chemistry consulting for projects, grant applications, synthetic chemistry, medicinal chemistry, and analytical chemistry, as well as access to equipment for synthesis, purification, and analysis.

Proper citation: Sanford Burnham Prebys Medical Discovery Institute Medicinal Chemistry Facility (RRID:SCR_014872) Copy   

•   Source: SciCrunch Registry

http://diabetesresearch.med.umich.edu/Core_MCDTR_Methods.php

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Research core that works to assist investigators in designing studies, collecting data, and analyzing data to examine questions related to the causes, prevention, and control of diabetes, its complications, and comorbidities.

Proper citation: Michigan Center for Diabetes Translational Research Methods and Measurements Core (RRID:SCR_015188) Copy   

•   Source: SciCrunch Registry

https://nationalmaglab.org/user-facilities/icr

Facility provides service operations for sample analysis that requires ultrahigh resolution and high mass accuracy of Fourier Transform Ion Cyclotron Resonance. Used for research in biomolecular analysis, hydrogen-deuterium exchange and environmental and petrochemical analysis. Four FT-ICR mass spectrometers feature high magnetic fields including the world-record 21 tesla and are compatible with multiple ionization and fragmentation techniques.

Proper citation: National High Magnetic Field Laboratory Ion Cyclotron Resonance Core Facility (RRID:SCR_017361) Copy   

•   Source: SciCrunch Registry