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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SISTEr
 
Resource Report
Resource Website
100+ mentions
SISTEr (RRID:SCR_001542) SISTEr resource, data or information resource, clinical trial, data set Clinical trial under the Urinary Incontinence Treatment Network to compare the treatment success for two surgical procedures that are frequently used and have similar cure rates, yet have not been compared directly to each other in a large, rigorously conducted randomized trial. The secondary aims of the trial are to compare other outcomes for the two surgical procedures, including quality of life, sexual function, satisfaction with treatment outcomes, complications, and need for other treatment(s) after surgery. Follow-up will be a minimum of two years and up to four years. urinary, incontinence, dataset, surgical procedure, outcome, quality of life, sexual function, satisfaction, treatment, complication, burch procedure, sling procedure, female, surgery is listed by: NIDDK Information Network (dkNET)
has parent organization: Urinary Incontinence Treatment Network
Urinary incontinence, Stress, Stress urinary incontinence NIDDK ;
NICHD
Free, Freely available nlx_152852 http://www.uitn.net/sister.asp SCR_001542 Stress Incontinence Surgical Treatment Efficacy Trial 2026-08-18 09:40:26 151
PSTC Nephrotoxicity Biomarkers
 
Resource Report
Resource Website
PSTC Nephrotoxicity Biomarkers (RRID:SCR_003709) PSTC Nephrotoxicity Biomarkers data or information resource, narrative resource, standard specification Urinary kidney biomarkers (KIM-1, albumin, total protein, 2-microglobulin, cystatin C, clusterin and trefoil factor-3) that are considered acceptable biomarkers for the detection of acute drug-induced nephrotoxicity in rats and can be included along with traditional clinical chemistry markers and histopathology in toxicology studies. These biomarkers may be used voluntarily as additional evidence of nephrotoxicity in nonclinical safety assessment studies to complement the standard data (BUN and sCr). In ROC analyses, some of these biomarkers showed better sensitivity and specificity than BUN and sCr relative to histopathological alterations considered to be the gold standard when tested with a limited number of nephrotoxicant and control compounds. biomarker, drug development, drug, urinary, urinary biomarker, gold standard, kim-1, albumin, total protein, beta2-microglobulin, cystatin c, clusterin, trefoil factor-3, kidney, nonclinical is recommended by: U.S. Food and Drug Administration
has parent organization: Drug Development Tools Qualification Programs
has parent organization: Predictive Safety Testing Consortium
Nephrotoxicity, Drug-induced nephrotoxicity Public nlx_157890 SCR_003709 Predictive Safety and Testing Consortium Drug-induced Nephrotoxicity Biomarkers, PSTC NWG Drug-induced Nephrotoxicity Biomarkers 2026-08-18 09:40:58 0
Life Extension: Laboratory and Blood Testing Services
 
Resource Report
Resource Website
Life Extension: Laboratory and Blood Testing Services (RRID:SCR_007167) analysis service resource, material analysis service, production service resource, biomaterial analysis service, service resource Blood testing is the single most important preventive tool you can use to help head off health problems. Life Extension makes it possible to take advantage of that tool at a fraction of the cost commercial blood labs charge. Get a picture of your overall health. Identify potential disease risks. Test for specific problems with comprehensive blood test panels and individualized tests like these: * Male and Female Comprehensive Panels * Cardiac Risk Factors * Vitamin Deficiencies * Hormone and Thyroid Panels * Metabolic and Chemistry Profiles blood, test, health, laboratory, cardiac, risk, male, female, vitamin deficiency, hormone, thyroid, metabolic, chemistry, cancer, heart, kidney, infections, immune, allergies, urinary, panel has parent organization: Life Extension Life Extension Foundation nif-0000-30206 SCR_007167 Blood Testing Services 2026-08-18 09:42:07 0
BodyMap-Xs
 
Resource Report
Resource Website
1+ mentions
BodyMap-Xs (RRID:SCR_001147) BodyMap-Xs database, data or information resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. A taxonomical and anatomical database of latest cross species animal EST data, clustered by UniGene and inter connected by Inparanoid. Users can search by Unigene, RefSeq, or Entrez Gene ID, or search for Gene Name or Tissue type. Data is also sortable and viewable based on qualities of normal, Neoplastic, or other. The last data import appears to be from 2008 expressed sequence tag, comparative genomics, anatomy, taxonomy, brain, blood, connective, reproductive, muscular, alimentary, lung, liver, urinary, endocrine, exocrine, embryo, homology, gene expression, ortholog, paralog has parent organization: DNA DataBank of Japan (DDBJ) Neoplasm, Normal Japanese Ministry of Education Culture Sports Science and Technology MEXT ;
New Energy and Industrial Technology Development Organization
PMID:16381946
PMID:11125076
PMID:10592203
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02617 http://bodymap.jp/, http://bodymap.ims.u-tokyo.ac.jp/ SCR_001147 BodyMap-Xs: anatomical and taxonomical breakdown of animal EST, BodyMap, BodyMap- human and mouse gene expression database, BodyMap: human and mouse gene expression database, BodyMap-cross species, BodyMap-Xs(cross species) 2026-08-18 09:40:25 1
Medtronic
 
Resource Report
Resource Website
1000+ mentions
Medtronic (RRID:SCR_003988) MDT commercial organization Medical technology company that develops and manufactures devices and therapies to treat more than 30 chronic diseases, including heart failure, Parkinson's disease, urinary incontinence, Down syndrome, obesity, chronic pain, spinal disorders, and diabetes. A Commercial healthcare organization for both patients and healthcare professionals. For professionals, it provides products, therapy and procedure solutions, and services. medical device, cardiac, vascular, restorative therapy, neuromodulation, spine, heart, aorta, coronary, surgical technology is related to: Kidney Health Initiative Cardiac disease, Vascular disease, Diabetes, Neurological condition, Musculoskeletal condition, Heart failure, Parkinson's disease, Urinary incontinence, Down's syndrome, Obesity, Chronic pain, Spinal disorder grid.481699.b, nlx_158399, Wikidata: Q30343856, SCR_010517, nlx_17750, grid.487289.8 https://ror.org/04fhmmg24, https://ror.org/01y0zfy93 SCR_003988 Medtronic Inc. 2026-08-18 09:41:10 2841
University Andrology Laboratory
 
Resource Report
Resource Website
University Andrology Laboratory (RRID:SCR_004901) UIC Andrology Laboratory material resource, biomaterial supply resource The University Andrology Laboratory provides physicians and their patients with all forms of male infertility testing, as well as operating a Patient Sperm Banking Program. This full-service facility is dedicated to the diagnosis and treatment of the infertile male using the highest standard of quality of care. Patients can either visit the main laboratory facility on the University of Illinois at Chicago Medical Center campus or visit our satellite laboratory on North Michigan Avenue. Now available through the University Andrology Laboratory is the OverNiteMale Program. The OverNiteMale Program is particularly convenient for patients who are unable to make a personal visit to one of our laboratories to produce a sample. Patients can now produce a sample in the privacy of their own home from any location in the U.S.A. and send it via Federal Express directly to our laboratory. In-patients can also take advantage of the OverNiteMaleTM Program during their hospital stay. The University Andrology Laboratory was originally introduced at Michael Reese Hospital in Chicago in 1982 and relocated in 1996 to the University of Illinois at Chicago Medical Center, Department of Urology. The laboratory meets the highest standard of quality control and quality assurance. The operation of the University Andrology Laboratory has been under the direction of Gail S. Prins, Ph.D., HCLD, from its inception to the present. is listed by: One Mind Biospecimen Bank Listing
has parent organization: University of Illinois College of Medicine; Illinois; USA
Andrology nlx_87124 SCR_004901 2026-08-18 09:41:26 0
International Biologics, LLC
 
Resource Report
Resource Website
International Biologics, LLC (RRID:SCR_004212) tissue bank, material resource, biomaterial supply resource International Biologics is a fully accredited American Association of Tissue Banks (����??AATB����??) Tissue Bank and Processing Facility --- Accreditation #00162. It receives 100% of it''s donor tissue from federally licensed Organ Procurement Organizations (OPO����??s) and other AATB accredited donor sources. International Biologics provides multitudinous bone and soft tissue allografts. Clinical applications for these products include: Orthopedic, Spine, Joint Restoration, Oral Maxillofacial, Podiatry, Periodontal, Urology, Trauma The collection and distribution of donated tissue including soft tissue, bone tissue and organ donation of kidneys, livers and hearts (collectively tissue) are controlled by the Government. Organ Procurement Organizations (OPOs) have long been established in every state to recover tissue from donors. Because there is a very short period following death before tissue breaks down rendering it useless for implantation, OPOs maintain round-the-clock presences in hospitals including grief counseling through procurement personnel. OPO tissue is heavily federally regulated and is therefore the most highly sought tissue because it is universally understood to be the safest tissue for transplant. International Biologics has long-term high-volume OPO tissue supply contracts making it one of the largest recipients of cadaveric bone and soft tissue in the world. International Biologics processes its tissue within a state-of-the-art facility located in Scottsdale, Arizona. The facility includes nine -86C ultra low temperature freezers, 14 tray lyophilization, and four validated class 1000 clean rooms including CNC. is listed by: One Mind Biospecimen Bank Listing nlx_23433 SCR_004212 International Biologics 2026-08-18 09:41:06 0
NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources
 
Resource Report
Resource Website
NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources (RRID:SCR_003074) resource, portal, topical portal, data or information resource THIS RESOURCE IS NO LONGER IN SERVICE, documented May 23, 2017. This website contains resources for obesity researchers including: Obesity Databases, Registries and Information; Obesity Multicenter Clinical Research; Obesity Basic Research Networks; Obesity Reagents; Obesity Services; Obesity Standardization Programs; Obesity Tissues, Cells, Animals; Obesity Useful Tools. diabetes, type 1 diabetes, digestive disease, genetic metabolic disease, gene therapy, hematologic disease, hiv/aids research, immunological disease, kidney disease, liver disease, obesity, pancreas, urological disease, biotechnology, endocrinology, epidemiology, genetics, genomics, molecular hematology, molecular therapy, cystic fibrosis, polycystic kidney disease is related to: Rodent Operant Bucket project
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is parent organization of: CKD Biomarkers Consortium
Type 1 diabetes, Type 2 diabetes, Diabetes NIDDK THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00551 SCR_003074 NIDDKObesity Resources 2026-08-18 09:40:58 0
Visible Mouse Anatomy
 
Resource Report
Resource Website
Visible Mouse Anatomy (RRID:SCR_001603) Visible Mouse Anatomy data or information resource, narrative resource, video resource, training material, atlas, reference atlas Access to Quicktime movies of histologic mouse anatomy including heart / lung, kidney, mammary gland, lymph node, prostate, spleen, liver, salivary glands, and 3-D wire model based on MRI sections; a Quicktime mouse radiographic atlas of skeletal anatomy containing a series of radiographic images with color overlays and labels; and a table containing a comparison between mouse and human anatomy. Special topics include the virtual necroscopy. Anatomic systems cover the central nervous system, male genital-urinary tract, female genital-urinary tract, mammary, kidney, skeletal, cardiovascular, gastrointestinal, and respiratory systems. The pathology and imaging section includes anatomy, histology, comparative imaging, physiology, pathology, comparative mammary, comparative prostate, GEM, and an image archive. These pages were put together as a pilot demonstration by Dr. Robert Cardiff, UCD Center for Comparative Medicine with the collaboration of Dr. Michael Paulus, Oak Ridge National Laboratories,MicroCat Group, Dr. Allan Johnson, Duke University Center for In Vivo Microscopy, and Drs. Steve Griffey, Gary Henderson and Tom Jue, University of California, Davis. This is a work in progress and for demonstration purposes. anatomy, radiographic image, image, heart, lung, kidney, mammary gland, lymph node, prostate, spleen, liver, salivary gland, histology, necropsy, central nervous system, male, female, skeletal, genital-urinary tract, mammary, cardiovascular, gastrointestinal, respiratory, comparative has parent organization: Visible Mouse Project THIS RESOURCE IS NO LONGER IN SERVICE nlx_153861 SCR_001603 Mouse Anatomy - The Visible Mouse, The Visible Mouse - Anatomy 2026-08-18 09:40:24 0
Feinstein Institute for Medical Research
 
Resource Report
Resource Website
Feinstein Institute for Medical Research (RRID:SCR_004470) Feinstein Institute institution The Feinstein Institute for Medical Research is the research branch of the North Shore-Long Island Jewish Health System. Biomedical research has been a vital aspect of its two academic medical centers North Shore University Hospital and Long Island Jewish Medical Center since their establishment in the early 1950''s. Through its connection to the hospital system, the Institute bridges the gap between biomedical research and patient care, accessing hundreds of thousands of patients in the health system''s 15 hospitals, four long-term care facilities, three trauma centers, six home health agencies and dozens of outpatient facilities. Institute scientists collaborate with clinicians throughout the system to shed light on basic biological processes underlying disease. This knowledge is used to develop new therapies and diagnostics. Currently, more than 800 scientists and investigators are conducting research in oncology, immunology and inflammation, genetics, psychiatry, neurology, pediatrics, surgery, urology, obstetrics/gynecology and many other specialties. In 2008, the Feinstein received funding from the National Institutes of Health in excess of $28 million, and an additional $10 million from other federal sources. Total annual research funding from all sources exceeded $44 million in 2008. We stand at the threshold of an extraordinary time in medicine. Over the last 100 years, biomedical science has progressed very rapidly. Advances coming from the integration of genomics, proteomics and bioinformatics into the biomedical toolkit hold the promise that this transformation will continue well into the 21st century. The Feinstein Institute for Medical Research is a growing force in research innovation, education and progress. biomedical research, research is related to: Biomarkers of Anti-TNF Treatment Efficacy in Rheumatoid Arthritis - Unresponsive Populations
is parent organization of: Feinstein Biorepository
is parent organization of: Biomarkers of Anti-TNF Treatment Efficacy in Rheumatoid Arthritis - Unresponsive Populations
is parent organization of: Genetic Analysis Software
NIH ISNI: 0000 0000 9566 0634, Wikidata: Q7733638, grid.250903.d, nlx_143748 https://ror.org/05dnene97 SCR_004470 Feinstein Institute 2026-08-15 11:22:58 0
Behavior Enhances Drug Reduction of Incontinence
 
Resource Report
Resource Website
Behavior Enhances Drug Reduction of Incontinence (RRID:SCR_001495) BE-DRI resource, data or information resource, clinical trial, bibliography Multi-center randomized clinical trial to determine if the addition of behavioral treatment to drug therapy for the treatment of urge incontinence will make it possible to discontinue the drug and still maintain a reduced number of accidents. The most popular treatments for urge incontinence are drug therapy and behavior therapy, each with its own limitations. In this clinical study, the Urinary Incontinence Treatment Network (UITN) aims to determine differences with the addition of behavioral treatment to drug therapy alone. drug therapy, behavioral therapy, female, urinary incontinence, overactive bladder, combined modality therapy, quality of life, pelvic floor muscle exercise, tolterodine, clinical is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
has parent organization: Urinary Incontinence Treatment Network
Urge incontinence, Urinary Incontinence NIDDK U01DK58225;
NIDDK U01DK58234;
NIDDK U01DK58229;
NIDDK U01DK58231;
NIDDK U01DK60397;
NIDDK U01DK60401;
NIDDK U01DK60395;
NIDDK U01DK60393;
NIDDK U01DK60380;
NIDDK U01DK60379
PMID:16919506 Free, Freely available nlx_152752 http://www.uitn.net/bedri.asp SCR_001495 2026-08-18 09:40:31 0
Pittsburgh Center for Kidney Research Single Nephron and Metabolomics
 
Resource Report
Resource Website
Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285) core facility, resource, access service resource, service resource Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest. single nephron, metabolomics, renal cells, cell analysis and function is listed by: NIDDK Information Network (dkNET)
has parent organization: Pittsburgh Center for Kidney Research
is organization facet of: Pittsburgh Center for Kidney Research
NIDDK P30DK079307;
University of Pittsburgh School of Medicine; Pennsylvania; USA ;
Icahn School of Medicine at Mount Sinai; New York; USA
Available to the research community SCR_015285 2026-08-18 09:44:20 0
RiVuR
 
Resource Report
Resource Website
1+ mentions
RiVuR (RRID:SCR_001539) RIVUR resource, clinical trial Multicenter, randomized, double-blind, placebo-controlled trial is designed to determine whether daily antimicrobial prophylaxis is superior to placebo in preventing recurrence of urinary tract infection (UTI) in children with vesicoureteral reflux (VUR). The basic eligibility criteria are: (1) age at randomization of at least 2 months, but less than 6 years, (2) a diagnosed first febrile or symptomatic UTI within 42 days prior to randomization that was appropriately treated, and (3) presence of Grade I-IV VUR based on voiding cystourethrogram (VCUG). Patients will be randomly assigned to treatment for 2 years with daily antimicrobial prophylaxis (trimethoprim-sulfamethoxazole) or placebo. The study is designed to recruit 600 children (approximately 300 in each treatment group) over an 18-24 month period. The primary endpoint is recurrence of UTI. In addition, patients will be evaluated for secondary endpoints related to renal scarring and antimicrobial resistance. Scarring will be determined based on renal scintigraphy by 99mTc dimercaptosuccinic (DMSA) scan. Quality of life, compliance, safety parameters, utilization of health resources, and change in VUR will be assessed periodically throughout the study. child, antimicrobial prophylaxis, placebo, antibiotic, renal scarring, pediatric, trimethoprim-sulfamethoxazole, intervention, kidney, antibiotic resistance, young human, infant, bibliography, clinical, trimethoprim, sulfamethoxazole is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
Vesico-ureteral reflux, Urinary tract infection NIDDK PMID:19570724
PMID:19018048
PMID:18076937
PMID:19018047
PMID:19086141
Free, Freely available nlx_152848 http://www.cscc.unc.edu/rivur/ SCR_001539 Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR), Randomized Intervention for Children with Vesicoureteral Reflux, Randomized Intervention for Vesicoureteral Reflux 2026-08-17 09:31:28 1
Human Physiology
 
Resource Report
Resource Website
Human Physiology (RRID:SCR_003525) Human Physiology wiki, data or information resource, narrative resource, book Human Physiology is a featured book on Wikibooks because it contains substantial content, it is well-formatted, and the Wikibooks community has decided to feature it on the main page or in other places. Please continue to improve it and thanks for the great work so far! A printable and PDF version are available. You can edit its advertisement template. Contents: 1. Homeostasis 2. Cell Physiology 3. Integumentary System 4. The Nervous System 5. Senses 6. The Muscular System 7. Blood Physiology 8. The Cardiovascular System 9. The Immune System 10. The Urinary System 11. The Respiratory System 12. The Gastrointestinal System 13. Nutrition 14. The Endocrine System 15. The Male Reproductive System 16. The Female Reproductive System 17. Pregnancy and Birth 18. Genetics and Inheritance 19. Development: Birth through Death 20. Appendix 1: Answers to Review Questions 21. Authors 22. Further Reading anatomy, human, physiology, image has parent organization: Wikibooks nlx_10645 SCR_003525 2026-08-18 09:41:05 0
Bovine Gene Atlas
 
Resource Report
Resource Website
1+ mentions
Bovine Gene Atlas (RRID:SCR_010580) BGA data or information resource, atlas, expression atlas A compendium of over 7.2 million unique 20 base transcript tags profiled from 81 tissues acquired from the cow L1 Dominette 01449 , her male fetus, her 255 day old heifer calf, and her father. The BGA tags were generated on Illumina''s GA1 sequencing platform. L1D''s genome (build: 3.1) was sequenced at the Baylor College of Medicine and Genome Canada sequenced EST and full-length transcripts from the same tissues used for the BGA. Tissues were chosen as a source of total RNA to minimize sequence differences between cDNA tags and genomic or expressed sequence and increase the probability of unequivocally mapping tags to build 3.1. The BGA is comprised of cardiovascular, digestive, endocrine, lymphatic, muscular, nervous system, reproductive and urinary tissues sampled from animals in the fetal, juvenile, and adult stages of development. This cover is a portal to view the tags positioned on the 3.1 build using GBrowse, and a new database schema for positional and functional queries. gene expression, neuroanatomy has parent organization: Mississippi State University; Mississippi; USA USDA Cooperative State Research NRI-Animal genome reagent and tool development 2006-35616-16648;
USDA Agricultural Research Service project 1265-31000-098 D;
USDA Agricultural Research Service project 5438-31000-073 D
PMID:20961407 nlx_43343 SCR_010580 Bovine Gene Atlas: An Extensive Compendium of Bovine Transcript Profiles 2026-08-18 09:43:15 2
Renin Angiotensin System Study
 
Resource Report
Resource Website
1+ mentions
Renin Angiotensin System Study (RRID:SCR_013385) RASS/B-RASS, RASS resource, clinical trial Randomized, multicenter, double-blind study to determine if renin angiotensin medications, either losartan (angiotensin II blocker) or enalapril (converting enzyme inhibitor), can prevent or delay the onset of diabetic kidney disease in patients with type 1 diabetic patients who do not have hypertension, diabetic nephropathy, or predictive levels of microalbuminuria. Two hundred eight five patients ages 16-61 with 2-20 yrs of Type 1 Diabetes Mellitus and no renal functional abnormalities were randomized into a parallel, double-blind, placebo-controlled study involving 3 groups (95 patients/group). Each group received an angiotensin-converting enzyme inhibitor (ACEI) (enalapril), or an angiotensin II receptor blocker (Losartan), or placebo. All patients had their usual Diabetes Mellitus (DM) management. Baseline studies included measures of glomerular filtration rate (GFR), urinary albumin excretion rate (UAE), blood pressure (BP), and a percutaneous renal biopsy. Patients were followed by quarterly measures of BP, HbA1C, UAE, and drug compliance. There were annual measures of GFR and a repeat renal biopsy after 5 yrs in the study. The main endpoint is kidney structural changes over time, especially mesangial fractional volume (v(Mes/glom)). Secondary endpoints will be other DN structural measures and measures of kidney function (UAE, GFR). These studies will determine whether rennin angiotensin system blockage in the early stages of DN can prevent the early kidney structural changes in this important disorder. Ancillary studies will evaluate the effects of treatment group on the development and progression of diabetic retinopathy and will develop predictors of study participants'''' compliance. Baseline, 2.5 and 5 year retinal fundus photographs in the RASS patients were obtained. enalapril, drug, losartan, angiotensin, medication, kidney, intervention, clinical, adolescent, adult human, renal biopsy, renin-angiotensin system, diabetic nephropathy, kidney, placebo, glomerular filtration rate, urinary albumin excretion rate, blood pressure is related to: NIDDK Information Network (dkNET)
has parent organization: ClinicalTrials.gov
has parent organization: University of Minnesota Twin Cities; Minnesota; USA
Type 1 diabetes, Diabetic kidney disease, Retinopathy, Nephropathy, Diabetes NIDDK PMID:19571282 nlx_152849 SCR_013385 Renin Angiotensin System Blockage-DN (RASS), Renin Angiotensin System Study (RASS/B-RASS) 2026-08-17 09:34:45 1
Polycystic Kidney Disease Outcomes Consortium
 
Resource Report
Resource Website
Polycystic Kidney Disease Outcomes Consortium (RRID:SCR_003674) PKDOC data or information resource, portal, consortium, organization portal Consortium to develop evidence supporting the use of imaging Total Kidney Volume (TKV) as a prognostic biomarker that predicts the progression of Autosomal Dominant Polycystic Kidney Disease (ADPKD) to select patients likely to respond to therapy into clinical trials. It aims to replace the currently used measurement of glomerular filtration rate (GFR). Scientists will use the data collected to develop a disease progression model that will evaluate the relationship between TKV and the known complications of ADPKD, including rate of loss of kidney function, hypertension, gross hematuria, kidney stones, urinary tract infections, development of end-stage renal disease, and mortality. These analyses will be used to support the regulatory qualification of TKV as an accepted measure for assessing the progression of ADPKD in clinical trials in which new therapies are tested. PKDOC has the following goals: # Develop standard clinical data elements and definitions that are specific to ADPKD # Create a database of aggregated data from existing multiple, longitudinal, and well-characterized research registries maintained over decades by the leading institutions in ADPKD clinical investigation # Advance and harmonize the missions of regulatory agencies by creating tools that help with the evaluation of new pharmaceutical compounds # Develop a quantitative disease progression model to examine the linkage between TKV and disease outcomes consortium, drug, imaging, total kidney volume, biomarker, rate, disease progression, imaging biomarker, drug development, kidney volume, kidney, clinical, common data element, therapeutic, clinical trial, standard specification, database is listed by: Consortia-pedia
has parent organization: Critical Path Institute; Arizona; USA
PKD Foundation ;
Philanthropic donations ;
U.S. Food and Drug Administration
nlx_157909 SCR_003674 PKD Outcomes Consortium, PKD Consortium, Polycystic Kidney Disease (PKD) Outcomes Consortium 2026-08-18 09:41:07 0
Family Investigation of Nephropathy of Diabetes
 
Resource Report
Resource Website
Family Investigation of Nephropathy of Diabetes (RRID:SCR_001525) FIND, F.I.N.D. resource, clinical trial Multicenter observational study designed to identify genetic determinants of diabetic nephropathy. It is conducted in eleven U.S. clinical centers and a coordinating center, and with four ethnic groups (European Americans, African Americans, Mexican Americans, and American Indians). Two strategies are used to localize susceptibility genes: a family-based linkage study and a case-control study using mapping by admixture linkage disequilibrium (MALD). In the family-based study, probands with diabetic nephropathy are recruited with their parents and selected siblings. Linkage analyses will be conducted to identify chromosomal regions containing genes that influence the development of diabetic nephropathy or related quantitative traits such as serum creatinine concentration, urinary albumin excretion, and plasma glucose concentrations. Regions showing evidence of linkage will be examined further with both genetic linkage and association studies to identify genes that influence diabetic nephropathy or related traits. Two types of MALD studies are being done. One is a case-control study of unrelated individuals of Mexican American heritage in which both cases and controls have diabetes, but only the case has nephropathy. The other is a case-control study of African American patients with nephropathy (cases) and their spouses (controls) unaffected by diabetes and nephropathy; offspring are genotyped when available to provide haplotype data. The specific goals of this program: * Delineate genomic regions associated with the development and progression of renal disease(s) * Evaluate whether there is a genetic link between diabetic nephropathy and diabetic retinopathy * Improve outcomes * Provide protection for people at risk and slow the progression of renal disease * Help establish a resource for genetic studies of kidney disease and diabetic complications by creating a repository of genetic samples and a database * Encourage studies of the genetics of progressive renal disease genetic susceptibility, genetic pathway, renal, kidney, outcome, gene, genetics, european-american, african-american, mexican-american, american-indian, linkage association study, admixture linkage disequilibrium, mapping by admixture linkage disequilibrium, serum creatinine, urinary protein excretion, plasma glucose level, blood pressure, blood lipid level, trait, linkage, adult human, male, female, clinical is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
NIDDK 5R01DK053591 PMID:15642484 Free, Freely available nlx_152825 https://www.niddkrepository.org/studies/find/ SCR_001525 Family Investigation of Nephropathy and Diabetes (F.I.N.D.), Family Investigation of Nephropathy & Diabetes 2026-08-17 09:31:28 0
Internet Atlas of Histology
 
Resource Report
Resource Website
Internet Atlas of Histology (RRID:SCR_001745) data or information resource, narrative resource, slide, training material, curriculum material, topical portal, portal This portal leads to the Internet Atlas of Histology. This atlas allows you to explore the complete set of histological specimens that features many excellent plastic sections prepared by Aulikki Kokko-Cunningham, M.D. Also called University of Illnois at Urbana-Champaign, the College of Medicine: Internet Atlas of Histology Over 1000 labeled histological features are labeled and have accompanying functional descriptions. All of this information is accessible though an alphabetical index and a search engine. This resource has images categorized in: - Slides: Links to all of the specimens - Objects:Index of histological features Sponsors: This resource is supported by UIUC. electron micrograph, electron microscopy, endocrine, epithelium, female reproductive system, blood, bone, bone marrow, cell, circulatory system, connective tissue, cross section, digestive tract, histology, immune system, light microscopy, male reproductive system, muscle, nervous system, object, respiratory system, scanning electron microscopy (sem), sense organ, skin, specimen, tissue, transmission electron microscopy (tem), urinary system, image has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA Free, Freely Available nif-0000-10251 https://histo.life.illinois.edu/histo/atlas/index.php SCR_001745 UICU Histology Atlas 2026-08-18 09:40:38 0
NICHD Brain and Tissue Bank for Developmental Disorders
 
Resource Report
Resource Website
10+ mentions
NICHD Brain and Tissue Bank for Developmental Disorders (RRID:SCR_003601) NICHD BTB tissue bank, brain bank, material resource, biomaterial supply resource The objective of this human tissue repository is to systematically collect, store, and distribute brain and other tissues for research dedicated to the improved understanding, care, and treatment of individuals with developmental disorders. Brain sections are primarily frozen in isopentane / dry ice. Tissues are stored in 10% formalin and frozen at -85 degrees C. Of special interest are individuals with Down syndrome and other chromosomal defects, mitochondrial encephalopathies, phenylketonuria and other aminoacidopathies, maternal PKU, Rett syndrome, leukodystrophies, lysosomal disorders, dyslexia, autism, and other neurodevelopmental disorders. The brain and tissue banks have extensive experience in arranging for the rapid retrieval of tissue upon the death of individuals who die while at home, in hospitals or hospice care. As a special service, the brain and tissue banks are able to assist researchers who are working with patients who intend to donate tissues at the time of their death. Immediately after retrieval of the tissue, the brain and tissue banks will forward needed tissue to the referring investigators and ensure proper storage and cataloging of any additional tissues as part of the brain and tissue banks. The recipient of tissue and the brain and tissue banks are required to sign a Tissue Transfer Agreement before any tissues are transferred. downloadable catalog, tissue, brain, body fluid, cardiovascular system, endocrine system, genital system, gastrointestinal system, hematopoietic system, integumentary, musculo-skeletal, respiratory system, spinal cord, nerve, urinary system, other, rna, frozen, fixed, developmental disorder, down syndrome, chromosomal defect, mitochondrial encephalopathy, phenylketonuria, maternal pku, rett syndrome, dyslexia, autism, neurodevelopmental disorder, aminoacidopathy, pervasive development disorder, leukodystrophy, lysosomal disorder, s syndrome is listed by: One Mind Biospecimen Bank Listing
is listed by: Multiple Sclerosis Discovery Forum
is related to: One Mind Biospecimen Bank Listing
is related to: Multiple Sclerosis Discovery Forum
has parent organization: University of Maryland School of Medicine; Maryland; USA
Developmental disorder, Down syndrome, Chromosomal defect, Mitochondrial encephalopathy, Phenylketonuria, Maternal PKU, Rett Syndrome, Dyslexia, Autism, Neurodevelopmental disorder, Aminoacidopathy, Pervasive Development Disorder, Leukodystrophy, Lysosomal disorder, S syndrome NIH Blueprint for Neuroscience Research contract HHSN275200900011C;
NICHD NO1-HD-9-0011
Public: Tissues are made available to academic researchers and commercial enterprises for basic research. nif-0000-00217 SCR_003601 Eunice Kennedy Shriver NICHD BTB, NICHD Brain and Tissue Bank, NICHD Brain Tissue Bank for Developmental Disorders, NICHD BTB for Developmental Disorders 2026-08-18 09:41:04 39

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