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https://pathology.med.upenn.edu/research/core-resources/tumor-tissue-biospecimen-bank

Centralized biorepository of human biosamples. TTAB is responsible for the collection, processing, and storage of human blood, fluid, and tissue at the University of Pennsylvania Health System. TTAB has a collection bench within Surgical Pathology Suite at Hospital of University of Pennsylvania (HUP).� Our collection bench sits adjacent to frozen section teams managing clinical sample collection and allowing for tight integration of tissue sample collection with clinical pathology teams.

Proper citation: University of Pennsylvania Perelman School of Medicine Tumor Tissue Biospecimen Bank Core Facility (RRID:SCR_022430) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/ifi/cytofservicecenter.html

CyTOF�enables multi-parametric high-dimensional single�cell analysis�of more than 40 markers per cell, with�minimal background and compensation�issues.�Core�offers variety of�CyTOF-related services including�reagent distribution, consultation,�antibody conjugation, and data acquisition.�

Proper citation: University of Pennsylvania Perelman School of Medicine IFI CyTOF Service Center Core Facility (RRID:SCR_022410) Copy   

•   Source: SciCrunch Registry

http://tools.thermofisher.com/content/sfs/manuals/nd-1000-v3.8-users-manual-8%205x11.pdf

Spectrophotometer for measurement and analysis of 1 ul samples with high accuracy and reproducibility. Full spectrum from 220nm to 750nm spectrophotometer utilizes patented sample retention technology that employs surface tension alone to hold sample in place. No need for cuvettes. Has capability to measure highly concentrated samples without dilution.

Proper citation: Thermo Fisher: Nanodrop 1000 Spectrophotometer (RRID:SCR_016517) Copy   

•   Source: SciCrunch Registry

https://timothyspringer.org/files/tas/files/biacore3000-instrument.pdf

Biacore 3000 processing unit is an established, label-free system for detailed studies of biomolecular interactions. The system delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The ability to recover and transfer interaction partners directly to MALDI targets for identification and further characterization makes the system highly applicable to fast identification of unknown interactants.

Proper citation: GE: Biacore 3000 Real Time Biomolecular Interaction Analyzer (RRID:SCR_018044) Copy   

•   Source: SciCrunch Registry

https://sites.manchester.ac.uk/bioms/

Core offers mass spectrometry services and associated technologies to the University of Manchester and beyond with focus on biological molecules such as proteins and metabolites in proteomics and metabolomics areas.Provides support from experimental design to advanced sample preparation and data processing and interpretation.

Proper citation: University of Manchester BioMS Core Facility (RRID:SCR_020987) Copy   

•   Source: SciCrunch Registry

http://www.rockefeller.edu/ddrc/

Core guides researchers in drug discovery by improving efficiency of their bioassays, identifying compounds and targets of function, and in utilizing technologies for measurement of drug/receptor interactions.Center also has spectroscopic and calorimetric equipment for use in studies of interactions of drugs with their targets.

Proper citation: Rockefeller University Fisher Drug Discovery Core Facility (RRID:SCR_020985) Copy   

•   Source: SciCrunch Registry

http://www.rockefeller.edu/genomics/

Core offers services and instruments to support genomics research. Houses Illumina NovaSeq, NextSeq, MiSeq sequencers, 10X Genomics Chromium Single Cell System, and Life Technologies QuantStudio 12K flex realtime PCR system. Provides several accessory instruments for sample quantity and quality validation: Agilent Bioanalyzer, Agilent TapeStation, NanoDrop spectrophotometer, and Qubit spectrophotometer.Offers full services for genomic DNA-Seq and RNA-Seq, specializing in preparation of libraries from very small amount of starting total RNA. Users can also prepare their own libraries and use the center�s sequencing-only services. Offers free consultations on experimental designs, library preparation options, sequencer choice, sequencing depth and coverage, and biological replicates.Performs initial sequencing data analysis for all users, and can assist with downstream analysis.

Proper citation: Rockefeller University Genomics Resource Center Core Facility (RRID:SCR_020986) Copy   

•   Source: SciCrunch Registry

https://bsp.web.unc.edu/

Centralized, quality controlled facility and biorepository for processing, storage and disbursement of human specimens.Offers high throughput processing of human biospecimens, with specific emphasis on DNA and RNA isolation and purification.Provides laboratory support for investigator initiated large scale clinical, epidemiologic, and other studies.Functions as human specimen biorepository resource for clinicians who wish to store and study samples from unusual or potentially important patients.Biorepository is managed by custom LIMS, with sample accessioning, tracking and audits at each step.Provides scientific resource for investigators seeking advice or consultation on study design including specimen collection and storage methods, and human subject issues. Core staff act as liaison to other UNC core facilities and outside collaborators.

Proper citation: University of North Carolina at Chapel Hill Biospecimen Processing Core Facility (RRID:SCR_021290) Copy   

•   Source: SciCrunch Registry

https://pennstatehealthnews.org/topics/cryo-em/

Cryo-electron microscopy (cryo-EM) facility providesTitan Krios cryo-transmission electron microscope that is fully equipped for high-throughput data collection of the utmost quality possible. It has the ability to determine the atomic structure of a single protein or view molecules interacting in their cellular context. Provides guidance, training or data collection for researchers at the College of Medicine.Equipment includes Zeiss LSM 980 Cryo-Confocal Microscope,300 kV Krios Cryo-TEM for SPA and tomography, Equipped with Volta phase plates, bioquantum energy filter and K3 direct electron detector,200 kV thermionic JEOL 2100 for cryo-imaging, cryo-tomography, and standard imaging of stained grids.

Proper citation: Penn State Hershey College of Medicine cryo-EM Core Facility (RRID:SCR_021178) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/compchem/index.html

Core offers wide variety of services, including access to the Schrodinger platform and high-throughput computing. Services include examining molecular structures and mechanisms in atomic detail and provide graphically rich analysis suitable for inclusion in publications and grants.

Proper citation: University of Nebraska Medical Center Computational Chemistry Core Facility (RRID:SCR_021023) Copy   

•   Source: SciCrunch Registry

https://miap.eu/miap-unit/life-imaging-center/

Central core facility open to members of all faculties and the university clinic. Consists of 14 rooms in the Center for Integrative Signalling Analysis with 9 microscopy rooms with 20 microscope set-ups (3D-STED, confocal FLIM, two 2-photon confocal microscopes, 4 conventional confocal microscopes, lightsheet microscope, 4 high-end widefield ratio-imaging set-ups, 4 fluorescence stereo microscopes, 3 special set-ups for screening. LIC microscopes are hosted in Biosafety level S2 and S1 environments, connected to a large wet lab area and a cell culture room, both Biosafety level S2 classified. Additionally, the LIC offers a large computer lab with 12 high-end workstations for image processing and analysis. The LIC also covers two additional rooms, hosting 3 LSM systems in a neighboring building of the Signalling Campus Freiburg (SCF).

Proper citation: University of Freiburg Life Imaging Center Core Facility (RRID:SCR_020968) Copy   

•   Source: SciCrunch Registry

https://www.cityofhope.org/patients/departments-and-services/pathology

Department of Pathology at City of Hope combines state-of-the-art laboratories equipped with the latest diagnostic techniques and advanced instrumentation with superior investigative skills to accurately and rapidly identify even the rarest and most complex diseases. Our experts provide comprehensive services, from initial diagnosis to monitoring of prognostic indicators throughout the treatment process.

Proper citation: City of Hope Department of Pathology Core Facility (RRID:SCR_020974) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/light-microscopy

Core provides resources for imaging model organisms, tissue, cells, biomaterials, and artificial structures and houses equipment including almost every light microscopy imaging modality presently available. Cell culture facilities are also available nearby as well as other routine items necessary for biological imaging and material imaging. This facility has been designated Nikon Centers of Excellence, thus providing unique opportunity for training, demonstration, instrument development, and research.We excel in use of telemicroscopy through use of remote imaging sessions, remote control of all instruments, and remote data analysis sessions available to all users.Provides training to all users that plan to conduct experimentation. Following an initial consultation in which experimental requirements, expected outcomes, and careful scrutiny of feasibility, training and/or access is arranged through the Director.

Proper citation: University of Massachusetts Light Microscopy Core Facility (RRID:SCR_021148) Copy   

•   Source: SciCrunch Registry

https://www.rockefeller.edu/cemrc/

Offers new cryo-electron microscopy tools available to University researchers, allowing for visualization of three-dimensional structures of molecules and macromolecular complexes in solution.

Proper citation: Rockefeller University Cryo Electron Microscopy Resource Center Core Facility (RRID:SCR_021146) Copy   

•   Source: SciCrunch Registry

https://www.bmh.manchester.ac.uk/research/facilities/electron-microscopy/

Offers expertise and equipment tailored for biological samples mostly. Houses four electron microscopes.Preparation laboratory includes range of specialised room temperature and cryo sample preparation equipment, ultramicrotomes and suite of computer workstations for image processing.Electron microscopy staff are available to train and assist.

Proper citation: University of Manchester Electron Microscopy Core Facility (RRID:SCR_021147) Copy   

•   Source: SciCrunch Registry

https://htrc.uchicago.edu

Coordinated, centralized, and dedicated program for procuring, processing, dispersing and assessing all types of biospecimens together with downstream histology services. CAP Accredited.

Proper citation: University of Chicago Human Tissue Resource Center Core Facility (RRID:SCR_019199) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/medicine/research/corefacilities/flow-cytometry-facility/index.html

Flow Cytometry Facility offers analytical flow cytometry, cell sorting and data analysis.Instruments include FACSArias, FACSCanto II, LSR-Fortessas, Attune NxT, and Amnis ImageStream mkII.

Proper citation: University of Alberta Faculty of Medicine and Dentistry Flow Cytometry Core Facility (RRID:SCR_019195) Copy   

•   Source: SciCrunch Registry

https://voices.uchicago.edu/confocal/

Offers microscopy imaging, including bright field color and DIC, fluorescence multi-dimension,TIRFM including bleaching, ablation, FLIM and high resolution, highspeed, high sensitivity, confocal, and physiologic techniques, STED, GSD3D, lightsheet selective plane illumination and lattice lightsheet structured illumination super resolution microscopy.

Proper citation: University of Chicago Integrated Light Microscopy Core Facility (RRID:SCR_019197) Copy   

•   Source: SciCrunch Registry

http://njms.rutgers.edu/research/mfrweb/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2022. Provides services in molecular biology with DNA sequencing, capillary and high throughput services, single cell sequencing services using 10X genomics and Drop-Seq platforms, Luminex, oligonucleotide synthesis (IDT), HPLC analysis and purification, real time PCR and others.

Proper citation: Rutgers New Jersey Medical School Molecular Resource Core Facility (RRID:SCR_019169) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/cryo-electron-microscopy-laboratory/

Shared resource hosting advanced cryo–electron microscopes fitted with direct detectors as well as equipment for sample preparation.

Proper citation: New York University School of Medicine Langone Health Cryo-Electron Microscopy Laboratory Core Facility (RRID:SCR_019202) Copy   

•   Source: SciCrunch Registry