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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
seq-annot
 
Resource Report
Resource Website
1+ mentions
seq-annot (RRID:SCR_018731) software application, software resource, software toolkit, standalone software Software Python package for annotating and counting genomic features in genomes and metagenomes. Software tools to facilitate annotation and comparison of genomes and metagenomes. Annotating, counting, comparison, genomic feature, genome, metagenome, metagenomics, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:seq-annot https://bio.tools/seq-annot SCR_018731 2026-09-19 12:56:10 1
TransDecoder
 
Resource Report
Resource Website
1000+ mentions
TransDecoder (RRID:SCR_017647) data processing software, software application, software resource, standalone software Software tool to identify candidate coding regions within transcript sequences, such as those generated by de novo RNA-Seq transcript assembly using Trinity, or constructed based on RNA-Seq alignments to genome using Tophat and Cufflinks.Starts from FASTA or GFF file. Can scan and retain open reading frames (ORFs) for homology to known proteins by using BlastP or Pfam search and incorporate results into obtained selection. Predictions can then be visualized by using genome browser such as IGV. Identify, candidate, coding, region, transcript, sequence, de novo, RNAseq, assembly, alignment, genome, open, reading, frame, homology, protein, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:transDecoder, OMICS_10852 https://bio.tools/TransDecoder, https://sources.debian.org/src/transdecoder/, https://github.com/TransDecoder/TransDecoder/wiki SCR_017647 , Find Coding Regions Within Transcripts 2026-09-19 12:56:08 1572
QuPath
 
Resource Report
Resource Website
1000+ mentions
QuPath (RRID:SCR_018257) data processing software, image analysis software, software application, software resource Open Source software package for digital pathology image analysis. Used for whole slide image analysis and digital pathology. Provides researchers with batch processing and scripting functionality, and extensible platform with which to develop and share new algorithms to analyze complex tissue images. Digital pathology, image analysis, whole slide image, batch processing, tissue image, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Queens University Belfast; Ireland; United Kingdom
Cancer Research UK Accelerator ;
Experimental Cancer Medicine Centre Network ;
Friends of the Cancer Centre ;
Invest Northern Ireland ;
Sean Crummey Memorial Fund ;
Tom Simms Memorial Fund
PMID:29203879 Free, Available for download, Freely available biotools:qupath https://bio.tools/qupath SCR_018257 2026-09-19 12:56:09 2084
FlowCal
 
Resource Report
Resource Website
1+ mentions
FlowCal (RRID:SCR_018140) data processing software, software application, software resource Open source software tool for automatically converting flow cytometry data from arbitrary to calibrated units. Can be run using intuitive Microsoft Excel interface, or customizable Python scripts. Software accepts Flow Cytometry Standard (FCS) files as inputs and is compatible with different calibration particles, fluorescent probes, and cell types. Automatically gates data, calculates common statistics, and produces plots. Converting flow cytometry data, arbitrary unit, calibrated unit, data gating, statistic, plot, data, bio.tools is listed by: Debian
is listed by: bio.tools
NDSEG Fellowship ;
NIAID R21 AI115014;
NSF Graduate Research Fellowship DGE 0940902;
NSF EFRI 1137266;
NSF MCB 1244135;
Office of Naval Research MURI N000141310074;
Office of Naval Research YIP N000141410487;
Welch Foundation
PMID:27110723 Free, Available for download, Freely available biotools:flowcal https://bio.tools/flowcal SCR_018140 Python Flow Cytometry Calibration Library 2026-09-19 12:56:09 6
halSynteny
 
Resource Report
Resource Website
1+ mentions
halSynteny (RRID:SCR_018127) data processing software, software application, software resource Software tool as conserved synteny block construction method for multiple whole-genome alignments. Implementation of DAG-based for reconstruction of synteny blocks from genome alignment. Conserved synteny, block construction method, genome alignment, DAG based reconstruction, synteny block, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:halSynteny https://bio.tools/halSynteny SCR_018127 Hierarchical Alignment Format Synteny 2026-09-19 12:56:09 4
CiLiQuant
 
Resource Report
Resource Website
CiLiQuant (RRID:SCR_019319) data processing software, software application, software resource Software tool to separate junction reads based on their linear or circular origin. Only non ambiguous junction reads are used to compare relative linear and circular transcript abundance. RNA, splicing, circular origin, separate junction reads, circular transcript abundance, linear transcript abundance, compare, bio.tools is listed by: bio.tools
is listed by: Debian
European Union's Horizon 2020 ;
FWO ;
Kom Op Tegen Kanker (Stand Up To Cancer) ;
Special Research Fund UGent ;
Stichting Tegen Kanker
Free, Available for download, Freely available biotools:ciliquant https://bio.tools/ciliquant SCR_019319 2026-09-19 12:56:11 0
SeqExpress
 
Resource Report
Resource Website
SeqExpress (RRID:SCR_007075) data processing software, software application, software resource A comprehensive analysis and visualization software package for gene expression experiments that provides: a number of clustering and analysis techniques; integrated gene expression and analysis result visualizations, integration with the Gene Expression Omnibus; and an optional data sharing architecture. GO is used to assign functional enrichment scores to clusters, using a combination of specially developed techniques and general statistical methods. These results can be explored using the in built ontology browsing tool or through the generated web pages. SeqExpress also supports numerous data transformation, projection, visualization, file export/import, searching, integration (with R), and clustering options. gene, gene expression, function, analysis, visualization, statistical analysis, windows, c#, gene function, chromosome location, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Gene Expression Omnibus
PMID:14988116 Free nlx_149285, biotools:seqexpress https://bio.tools/seqexpress SCR_007075 2026-09-19 12:55:56 0
RIKEN integrated database of mammals
 
Resource Report
Resource Website
RIKEN integrated database of mammals (RRID:SCR_006890) RIKEN integrated database of mammals data or information resource, database, portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16, 2019.
A database that integrates not only RIKEN''''s original large-scale mammalian databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists'''' Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
integration, network, standardization, biomedical, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Functional Annotation of the Mammalian Genome
is related to: Cerebellar Development Transcriptome Database
is related to: Ensembl
is related to: Mouse Genome Informatics (MGI)
is related to: OBO
has parent organization: RIKEN Yokohama Institute; Kanagawa; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:21076152 THIS RESOURCE IS NO LONGER IN SERVICE nlx_151886, biotools:riken https://bio.tools/riken SCR_006890 2026-09-19 12:55:56 0
epigenomix
 
Resource Report
Resource Website
1+ mentions
epigenomix (RRID:SCR_006407) epigenomix data processing software, software application, software resource Software package for the integrative analysis of microarray based gene expression and histone modification data obtained by ChIP-seq. The package provides methods for data preprocessing and matching as well as methods for fitting bayesian mixture models in order to detect genes with differences in both data types. epigenetic, gene expression, microarray, histone modification, chip-seq, classification, differential expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24403540 GNU Lesser General Public License, v3 biotools:epigenomix, OMICS_02205 https://bio.tools/epigenomix SCR_006407 epigenomix - Epigenetic and gene expression data normalization and integration with mixture models 2026-09-19 12:55:55 2
SOAPaligner/soap2
 
Resource Report
Resource Website
100+ mentions
SOAPaligner/soap2 (RRID:SCR_005503) SOAPaligner, SOAP2 data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Updated version of SOAP software for short oligonucleotide alignment that features in super fast and accurate alignment for huge amounts of short reads generated by Illumina/Solexa Genome Analyzer., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. next generation sequencing, alignment, short read, oligonucleotide, single-read, pair-end, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SOAP
PMID:19497933
DOI:10.1093/bioinformatics/btn025
THIS RESOURCE IS NO LONGER IN SERVICE biotools:soap2 https://bio.tools/soap2, https://sources.debian.org/src/soapaligner/ SCR_005503 2026-09-19 12:55:54 325
Pedigree-Draw
 
Resource Report
Resource Website
1+ mentions
Pedigree-Draw (RRID:SCR_008302) commercial organization, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Software application for pedigree drawing (entry from Genetic Analysis Software) gene, genetic, genomic, macos, bio.tools is listed by: Genetic Analysis Software
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154520, OMICS_00213, SCR_010795 SCR_008302 PEDIGREE/DRAW 2026-09-19 12:55:57 1
COILS: Prediction of Coiled Coil Regions in Proteins
 
Resource Report
Resource Website
100+ mentions
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) data processing software, software application, software resource COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1126/science.252.5009.1162 biotools:ncoils, OMICS_07850, nif-0000-30263 https://bio.tools/ncoils, https://sources.debian.org/src/ncoils/ https://sources.debian.org/src/ncoils/ SCR_008440 COILS Server 2026-09-19 12:55:57 169
Subread
 
Resource Report
Resource Website
1000+ mentions
Subread (RRID:SCR_009803) data processing software, software application, software resource Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread. read alignment, DNA-seq reads mapping, RNA-seq reads mapping, mutation discovery, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Rsubread
has parent organization: University of Melbourne; Victoria; Australia
Australian Government ;
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support
PMID:23558742 Free, Freely available OMICS_01255, biotools:subread https://bio.tools/subread, https://sources.debian.org/src/subread/ SCR_009803 2026-09-19 12:56:00 2138
GSA-SNP
 
Resource Report
Resource Website
10+ mentions
GSA-SNP (RRID:SCR_013109) GSA-SNP data processing software, software application, software resource A tool for the gene-set (or pathway) analysis of a genome-wide association study result. It accepts a genome-wide list of SNPs and their association P-values. It summarizes the SNP P-values into nearby genes. The gene-by-gene summary results are then further summarized by gene-sets such as Gene Ontology, KEGG pathways, or user-created gene-sets. Various standardization and statistical tests can be performed and the resulting gene-sets that pass a significance level after multiple-testing correction are reported. The tool is written in Java and is available as a standalone version. clinical neuroinformatics, computational neuroscience, imaging genomics, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Soongsil University; Seoul; South Korea
PMID:20501604 GNU General Public License v2 nlx_155765, biotools:gsa-snp https://bio.tools/gsa-snp SCR_013109 2026-09-19 12:56:01 18
Trim Galore
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
Trim Galore (RRID:SCR_011847) Trim Galore! data processing software, software application, software resource Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data. Automate, quality, adapter, trimming, remove, biased, methylation, position, RRBS, reduced, representation, bisulfite, data, sequence, wrapper, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
works with: cutadapt
Free, Available for download, Freely available biotools:trim_galore, OMICS_01096, SCR_016946 https://github.com/FelixKrueger/TrimGalore, https://bio.tools/trim_galore, https://sources.debian.org/src/trim-galore/ SCR_011847 TrimGalore 2026-09-19 12:56:01 7582
SPM
 
Resource Report
Resource Website
5000+ mentions
Issue
SPM (RRID:SCR_007037) SPM data analysis software, data processing software, image analysis software, software application, software resource Software package for analysis of brain imaging data sequences. Sequences can be a series of images from different cohorts, or time-series from same subject. Current release is designed for analysis of fMRI, PET, SPECT, EEG and MEG. analysis, brain, imaging, data, sequence, fMRI, PET, SPECT, EEG, MEG, bio.tools uses: Neuroimaging Data Model
uses: imcalc: SPM batch image calculator
is used by: rsfMRI_fconn calculation
is used by: Automatic Analysis
is used by: auto_acpc_reorient
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is affiliated with: Clinical Toolbox for SPM
is affiliated with: Statistical non-Parametric Mapping
is related to: WFU Biological Parametric Mapping Toolbox
is related to: vis: SPM Visualized Statistics toolbox
is related to: LEAD-DBS
is related to: CCHMC Pediatric Brain Templates
is related to: IBMA toolbox
is related to: ArtRepair for robust fMRI
is related to: ASL data processing tool box
is related to: BrainVISA / Anatomist
is related to: MRIcro Software
is related to: xjView: A Viewing Program For SPM
is related to: BrainMagix SPM Viewer
is related to: MarsBaR region of interest toolbox for SPM
is related to: NIRS-SPM
is related to: SPM SS - fMRI functional localizers
is related to: Wisconsin White Matter Hyperintensities Segmentation Toolbox
is related to: Dementia-specific FDG PET Template for SPM analyses
is related to: SPM Anatomy Toolbox
is related to: MIPAV: Medical Image Processing and Visualization
is related to: MATLAB
is related to: hMRI-toolbox
is related to: Sandwich Estimator Toolbox
has parent organization: University College London; London; United Kingdom
is required by: MRTool
provides: TSDiffAna
has plug in: ICN_Atlas
works with: UManitoba - JHU Functionally Defined Human White Matter Atlas
works with: NIAG Addiction Data
works with: ICN_Atlas
works with: spm_auto_reorient_coregister
works with: Computational Anatomy Toolbox for SPM
works with: FieldTrip
works with: POAS4SPM
Free, Available for download, Freely available biotools:SPM https://github.com/spm/spm12, https://bio.tools/SPM https://www.fil.ion.ucl.ac.uk/spm/ SCR_007037 Statistical Parametric Mapping, SPM5, SPM2, SPM12, Statistical Parametric Mapping Software, SPM99, SPM8, SPM, SPM96 2026-09-19 12:55:09 8748
MUSCLE
 
Resource Report
Resource Website
10000+ mentions
MUSCLE (RRID:SCR_011812) MUSCLE alignment software, analysis service resource, data analysis service, data analysis software, data processing software, image analysis software, production service resource, service resource, software application, software resource Multiple sequence alignment method with reduced time and space complexity.Multiple sequence alignment with high accuracy and high throughput. Data analysis service for multiple sequence comparison by log- expectation. bio.tools is used by: TranslatorX
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: PREFAB
has parent organization: European Bioinformatics Institute
PMID:15034147
PMID:15318951
DOI:10.1093/nar/gkh340
biotools:muscle, OMICS_00982 https://bio.tools/muscle, http://www.drive5.com/muscle/, https://www.drive5.com/muscle/manual/, https://www.drive5, http://bioconductor.org/packages/release/bioc/html/muscle.html.com/muscle/manual/install.html, https://sources.debian.org/src/muscle/ SCR_011812 MUltiple Sequence Comparison by Log- Expectation 2026-09-19 12:55:12 17169
neXtProt
 
Resource Report
Resource Website
100+ mentions
neXtProt (RRID:SCR_008911) data or information resource, database, portal, topical portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2025. Human protein knowledge platform. Knowledge platform for human proteins selects and filters high throughput data pertinent to human proteins from UniProtKB. Extends UniProtKB/Swiss-Prot annotations for human proteins to include several new data types. Protein, proteomics, sirna, 3d, pathway, variant, protein-protein interaction, protein-drug interaction, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: UniProtKB
has parent organization: SIB Swiss Institute of Bioinformatics
SIB ;
Swiss Commission for Technology and Innovation
PMID:22139911 THIS RESOURCE IS NO LONGER IN SERVICE biotools:nextprot, nlx_151482 https://bio.tools/nextprot SCR_008911 2026-09-19 12:55:11 177
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology
 
Resource Report
Resource Website
1000+ mentions
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology (RRID:SCR_008017) data acquisition software, data or information resource, data processing software, database, software application, software resource Harvester is a Web-based tool that bulk-collects bioinformatic data on human proteins from various databases and prediction servers. It is a meta search engine for gene and protein information. It searches 16 major databases and prediction servers and combines the results on pregenerated HTML pages. In this way Harvester can provide comprehensive gene-protein information from different servers in a convenient and fast manner. As full text meta search engine, similar to Google trade mark, Harvester allows screening of the whole genome proteome for current protein functions and predictions in a few seconds. With Harvester it is now possible to compare and check the quality of different database entries and prediction algorithms on a single page. Sponsors: This work has been supported by the BMBF with grants 01GR0101 and 01KW0013. function, gene, bioinformatics, data, database, human, meta search engine, prediction, protein, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Karlsruhe Institute of Technology; Karlsruhe; Germany
biotools:harvester, nif-0000-10169 https://bio.tools/harvester SCR_008017 Harvester IV 2026-09-19 12:55:10 1480
PLEXdb - Plant Expression Database
 
Resource Report
Resource Website
10+ mentions
PLEXdb - Plant Expression Database (RRID:SCR_006963) PLEXdb analysis service resource, data analysis service, data or information resource, data repository, database, portal, production service resource, service resource, storage service resource, topical portal PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets. gene expression, plant, plant pathogen, genotype, phenotype, genetic, physical, pathway, plant biology, compare, functional genomics, expression profiling, expression atlas, pathogen, genome, anova, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: FuncExpression
has parent organization: Iowa State University; Iowa; USA
UniNSF DBI-0543441;
NSF IOS-0922746;
USDA 3625-21000-049-00D
PMID:22084198 biotools:plexdb, r3d100011516, nlx_149236 https://bio.tools/plexdb, https://doi.org/10.17616/R39D13 SCR_006963 PLEXdb - Gene expression resources for plants and plant pathogens, Plant Expression Database 2026-09-19 12:55:09 21

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