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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
Stereo Investigator - Cleared Tissue Edition
 
Resource Report
Resource Website
Stereo Investigator - Cleared Tissue Edition (RRID:SCR_017668) data processing software, image analysis software, software application, software resource Software tool for unbiased stereology to be used on cleared tissue. Used to analyze intact, cleared tissue specimens imaged with light sheet or confocal microscopes. Includes number, length, area and volume analyses. Stereology, cleared, tissue, intact, speciment, imaged, confocal, microscopy, analysis, MBF Bioscience Restricted SCR_017668 SciCrunch Registry 2026-10-24 12:50:04 0
viral_seq
 
Resource Report
Resource Website
1+ mentions
viral_seq (RRID:SCR_018515) data processing software, software application, software resource Ruby Gem with bioinformatics tools for processing viral NGS data. Specifically for Primer-ID sequencing and HIV drug resistance analysis. Processing viral data, next generation sequencing data, viral data, sequencing, HIV drug resistance analysis, Primer ID sequencing, data Free, Available for download, Freely available https://github.com/ViralSeq/viral_seq SCR_018515 SciCrunch Registry 2026-10-24 12:50:05 2
EphysExtraction
 
Resource Report
Resource Website
1+ mentions
EphysExtraction (RRID:SCR_018193) data processing software, software application, software resource Software tool as code to extract electrophysiological parameters of neurons. Code is continuously being updated to handle more kinds of voltage traces and extract different kinds of features. electrophysiological parameter, extract parameter, neuron parameter, voltage trace, data Free, Available for download, Freely available SCR_018193 SciCrunch Registry 2026-10-24 12:50:04 3
HTStream
 
Resource Report
Resource Website
10+ mentions
HTStream (RRID:SCR_018354) data processing software, software application, software resource Software tool as quality control and processing pipeline for High Throughput Sequencing data. Uses tab delimited fastq format that allows for streaming from application to application. Interoperable with other standard Linux tools., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Next Generation Sequencing, data processing, quality control, data preprocessing THIS RESOURCE IS NO LONGER IN SERVICE SCR_018354 SciCrunch Registry 2026-10-24 12:50:04 13
Science of Behavior Change Research Network
 
Resource Report
Resource Website
1+ mentions
Science of Behavior Change Research Network (RRID:SCR_017385) SOBC data or information resource, portal, project portal Repository for behavioral science measures that have been validated or are in process of being validated in accordance with SOBC Experimental Medicine Approach. Data, behavioral, science, SOBC, measure, data, medicine NIH SCR_017388 https://scienceofbehaviorchange.org/measures/, https://scienceofbehaviorchange.org/measures/ SCR_017385 SciCrunch Registry SOBC Measures Repository, Science of Behavior Change (SOBC) Research Network 2026-10-24 12:50:02 1
Registration Software Mitra Lab
 
Resource Report
Resource Website
Registration Software Mitra Lab (RRID:SCR_018353) data processing software, software application, software resource Software package to align brain slice images in atlas free manner. Align, brain, brain slice, brain slice image, atlas free manner Free, Available for download, Freely available SCR_018353 SciCrunch Registry 2026-10-24 12:50:05 0
GeneSyntenyPipeline
 
Resource Report
Resource Website
GeneSyntenyPipeline (RRID:SCR_018198) data processing software, software application, software resource Software pipeline was designed to draw gene synteny plot between genomes and obtain 1 to 1 gene pairs from each genome. Genome, synteny, plot, JCVI, gene pair, data Free, Available for download, Freely available SCR_018198 SciCrunch Registry 2026-10-24 12:50:03 0
halSynteny
 
Resource Report
Resource Website
1+ mentions
halSynteny (RRID:SCR_018127) data processing software, software application, software resource Software tool as conserved synteny block construction method for multiple whole-genome alignments. Implementation of DAG-based for reconstruction of synteny blocks from genome alignment. Conserved synteny, block construction method, genome alignment, DAG based reconstruction, synteny block, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:halSynteny https://bio.tools/halSynteny SCR_018127 SciCrunch Registry Hierarchical Alignment Format Synteny 2026-10-24 12:50:03 4
Smart-seq2 Multi-Sample Pipeline
 
Resource Report
Resource Website
1+ mentions
Smart-seq2 Multi-Sample Pipeline (RRID:SCR_018920) data processing software, software application, software resource, software toolkit Software pipeline for single-nucleus RNAseq data generated by Smart-seq2 assays. Developed in collaboration with the BRAIN Initiative Cell Census Network (BICCN) to process single-nucleus RNAseq (snRNAseq) data generated by Smart-seq2 assays. Used to simultaneously process multiple libraries of single nuclei Smart-seq2 and Smart-seq4 data. For each library (nucleus), the pipeline trims paired FASTQ files, aligns trimmed reads to the genome, counts intronic and exonic reads, and calculates quality control metrics. Counts and metrics for all libraries are combined into merged Loom formatted count matrix. snRNAseq data, Smart-seq2 assays, single nucleus, multi sample, WARP repository is related to: Human Cell Atlas
has parent organization: University of California at San Diego; California; USA
has parent organization: Allen Institute
has parent organization: Broad Institute
is organization facet of: Terra
is organization facet of: BICCN
Free, Available for download, Freely available SCR_021312 https://app.terra.bio/#workspaces/warp-pipelines/Smart-seq2_Single_Nucleus_Muti-Sample https://github.com/broadinstitute/warp/tree/master/pipelines/skylab/smartseq2_multisample SCR_018920 SciCrunch Registry Multi-snSS2, Smart-seq2 Single Nucleus Multi-Sample (Multi-snSS2) 2026-10-24 12:50:05 4
BALBES
 
Resource Report
Resource Website
1+ mentions
BALBES (RRID:SCR_018763) software application, software resource, software toolkit, standalone software Software system for solving protein structures using x-ray crystallographic data. Automatic molecular replacement pipeline for molecular replacement in CCP4. Integrates into one system all components necessary for solving crystal structure by Molecular Replacement. System is automated so that it needs no user intervention when running combination of jobs such as model searching, molecular replacement and refinement. Molecular replacement pipeline, protein structure, solving protein structure, x-ray crystallographic data, molecular replacement, molecular replacement in CCP4, solving crystal structure, automated system, no user intervention, model searching, refinement uses: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: CCP4
NIGMS R01 GM069758;
Wellcome Trust
PMID:18094476 Free, Available for download, Freely available SCR_018763 SciCrunch Registry 2026-10-24 12:50:05 1
CustomCDF
 
Resource Report
Resource Website
1+ mentions
CustomCDF (RRID:SCR_018527) data processing software, software application, software resource Brainarray custom CDFs for processing raw Affymetrix data. Used to map probe to probesets. Oligonucleotide probes on GeneChips are reorganized based on latest genome and transcriptome information. Brainarray, custom CDF, processing raw Affymetrix data, data processing, map probe, probset, oligonucleotide probe, GeneChips, genome, transcriptome, data PMID:16284200 Free, Freely available https://gist.github.com/rmflight/3108891, https://rdrr.io/github/jakejh/metapredict/man/installCustomCdfPackages.html SCR_018527 SciCrunch Registry 2026-10-24 12:50:04 8
BioCurrents Research Center
 
Resource Report
Resource Website
BioCurrents Research Center (RRID:SCR_002020) BRC instrument supplier, material resource The BioCurrents Research Center (BRC) is an integrated technology resource of the NIH:NCRR. The activities of the Center focus on molecular physiology as it relates to the cell function and disease. Our particular interest is how the dynamics of cell responses are reflected in the chemical profiles of microdomains surrounding single living cells. In order to measure complex cellular boundary layers, the BRC has specialized in the development of extremely sensitive signal acquisition and processing methods along with miniaturized electrochemical sensor designs. The technique is non-invasive and termed self-referencing. Since its establishment in 1996, the BRC has directed its technological research and development to the design and application of ultra-microelectrodes (tip diameters of less than 10m) tailored for the detection of specific chemicals. These have been successfully applied to the boundary layer profiles of many different cell types, with thematic strength in diabetes research, reproductive health and development (see collaborative profiles). More recently, it is changing its focus to technical developments, enhancing the integrative approach to cell function. To understand a cell as a dynamic and integrated whole, BRC must be able to examine responses from different domains as near to real time and as synchronously as possible. To this end, it is developing imaging capabilities to work in parallel with electrochemistry and conventional electrophysiological techniques. Imaging includes a spinning disc confocal, as well as a low light/luminescent imager designed and built within the BRC. The technologies developed or under development are in high demand within the biomedical community. Over 40 investigators work with the Center each year in a collaborative or service capacity. Over 80 of our visitor pool is NIH funded, representing approximately 25 NIH divisions and institutes. As part of our training and dissemination program we host occasional workshops at major national and international meetings, train a significant number of new investigators each year and host graduate students undertaking portions of their thesis dissertation using our technologies. In dissemination we advise on, and install, electrochemical systems in off campus research endeavors, both academic and industrial. electrochemical, electrochemistry, electrophysiological, function, cell, cellular, chemical, confocal, development, diabetes, disease, health, imager, light, microdomain, microelectrode, physiology, reproductive, research, technique, technology has parent organization: Marine Biological Laboratory
is parent organization of: Pharmabase - an open content cheminformatics resource linking physiology with pharmacology
NCRR P41RR001395 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-24482 SCR_002020 SciCrunch Registry 2026-10-24 12:52:04 0
Adobe FormsCentral
 
Resource Report
Resource Website
Adobe FormsCentral (RRID:SCR_001729) FormsCentral commercial organization, service resource Service to create PDF and web forms. pdf, form, template is listed by: FORCE11 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156027 SCR_001729 SciCrunch Registry Adobe Forms Central 2026-10-24 12:52:04 0
fMRI Research Center at Columbia
 
Resource Report
Resource Website
10+ mentions
fMRI Research Center at Columbia (RRID:SCR_002658) PICS access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on 7/28/13. Core facility of Columbia Neuroscience with the goal of establishing a collaborative and multi-investigator neuroimaging environment that is focused on the investigation of the neurocircuitry of the brain that underlies cognition, perception and action, and also the development of clinical applications that enhance the goals of personalized medicine. Within this environment the specific current research interests of the Hirsch group include several related directions of investigation. The first is conscious and subconscious neural processes that mediate emotion and cognition in healthy individuals and in patients with psychiatric disorders. This direction also includes neurocircuitry that is characteristic of disorders of consciousness such as minimally conscious or vegetative states, self and visual awareness, and attention. Neurocircuitry of other complex cognitive processes such as decisions, inductive and deductive reasoning, language, truthfulness and top-down influences of expectation, reward, and regulation on early visual and mid-level perceptual and emotional systems. On-going projects targeted for clinical applications include benefits for neurosurgery such as the development of task batteries to map the cortical locations of essential functions such as language, motor, sensation, memory, emotion and sensory functions including visions, audition and the chemical senses. Computational innovations for labeling correspondence between brain structure and specific functional regions are under development to achieve the highest interpretive precision. Current projects include integration of EEG and fMRI techniques to localize seizuregenic cortex in relation to eloquent and functioning cortex for neurosurgical planning; integration of TMS and fMRI to discriminate essential and associative language-sensitive cortical areas; and integration of VEP, EEG and fMRI to inform assessments of visual disease secondary to stroke or neural degeneration. Projects intended to refine and enhance diagnosis of psychiatric disorders such as anxiety, depression, and eating disorders include development of specialized paradigms to target dysfunctional neurocircuitry such as emotional systems (amygdala and basal ganglia) and control and regulatory systems (cingulate and pre-frontal cortex). Comparison of before-treatment images with after-treatment images to inform models of both treatment and disease and investigation of the hypothesis that individual genetic and functional differences have predictive value for treatment options and outcome are currently underway. The lab has pioneered techniques for functional mapping of single patients, and operates an active clinical service for mapping individuals for neurosurgical planning, assessments of the neurocircuitry that underlie acquired or inherited disabilities and the mechanisms of neuroplasticity that restore lost functions are actively investigated using both groups and single subject studies. : fmri, imaging, neuroscience, cognitive sciences, cognition, perception, action, clinical, personalized medicine, neuroimaging, neurocircuitry, brain, vep, eeg has parent organization: Columbia University; New York; USA THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00405 SCR_002658 SciCrunch Registry Program for Imaging and Cognitive Sciences, Program for Imaging & Cognitive Sciences 2026-10-24 12:52:05 41
National Resource for Automated Molecular Microscopy
 
Resource Report
Resource Website
1+ mentions
National Resource for Automated Molecular Microscopy (RRID:SCR_001448) NRAMM biomedical technology research center, training resource Biomedical technology research center that develops, tests and applies technology aimed toward completely automating the processes involved in solving macromolecular structures using cryo-electron microscopy. The goal is to establish a resource that will serve both as a center for high-throughput molecular microscopy as well as for transferring this technique to the research community. Current Core Technology Research and Development is focused on 4 areas: improving grid substrates and specimen preparation; further automation and optimization of image acquisition; development of an integrated single particle analysis and processing pipeline; and the development of automated high throughput EM screening. NRAMM welcomes applications of both collaborative and service projects. macromolecular structure, cryo-electron microscopy, macromolecule, structure, microscopy, automation, high throughput, specimen handling, image acquisition, data processing, data information integration, structural biology technology center NIGMS 9 P41 GM103310;
NCRR 2P41RR017573
THIS RESOURCE IS NO LONGER IN SERVICE nlx_152671 SCR_001448 SciCrunch Registry 2026-10-24 12:52:04 2
Temporal-Lobe: Hippocampal - Parahippocampal Neuroanatomy of the Rat
 
Resource Report
Resource Website
1+ mentions
Temporal-Lobe: Hippocampal - Parahippocampal Neuroanatomy of the Rat (RRID:SCR_002816) Temporal-lobe.com data or information resource, data set Interactive diagram containing existing knowledge of hippocampal-parahippocampal connections in which any connection can be turned on or off at the level of cortical layers. It includes references for each connection. function, anatomical, connection, cortical, diagram, hippocampus, layer, neuroanatomy, neuroscience, parahippocampal, projection, subfield, temporal, lobe, topological, connectome, magnetic resonance, connectivity, formation, parahippocampal region, retrosplenial cortex, tract tracing is used by: NIF Data Federation
is used by: Integrated Nervous System Connectivity
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Rat Hippocampus Atlas
is related to: Integrated Manually Extracted Annotation
has parent organization: Norwegian University of Science and Technology; Trondheim; Norway
Research Council of Norway ;
various independent donations
PMID:21847380
PMID:19300446
Freely available, Account required nif-0000-24805 http://www.nitrc.org/projects/connectivity SCR_002816 SciCrunch Registry Parahippocampal-hippocampal network, TEMPORAL-LOBE, Parahippocampal hippocampal connectivity 2026-10-24 12:52:05 7
National Magnetic Resonance Facility at Madison
 
Resource Report
Resource Website
1+ mentions
National Magnetic Resonance Facility at Madison (RRID:SCR_001449) NMRFAM access service resource, service resource, training resource Provides access and developes NMR technology to advance range of applications and improves the efficiency, rigor and reproducibility of NMR data acquisition and analysis. Houses NMR spectrometers equipped with state-of-the-art probe technology and protocols to support acquisition of high-quality data. Spectrometers range from 500 MHz to 1100 MHz. Service is tailored to the needs of individual users and projects. Provides training and advice on experimental design, best practices for data acquisition, and data analysis. Experienced staff support users with training opportunities including workshops, video tutorials and protocols. nmr spectrometer, structure, function, protein, rna, dynamics, complex, membrane protein, paramagnetic protein, metabolomics, analysis, spectroscopy, nucleic acid, automation, data analysis, macromolecule, small angle x-ray scattering, structural biology technology center has parent organization: University of Wisconsin-Madison; Wisconsin; USA NIGMS P41136463;
NIGMS R24GM141526
Free, Freely Available nlx_152672 SCR_001449 SciCrunch Registry 2026-10-24 12:52:03 4
National Biomedical Center for Advanced ESR Technology
 
Resource Report
Resource Website
1+ mentions
National Biomedical Center for Advanced ESR Technology (RRID:SCR_001444) ACERT biomedical technology research center, training resource Biomedical technology research center that develops methods, both experimental and theoretical, of modern electron spin resonance (ESR) for biomedical applications. Center technologies are applicable to the determination of the structure and complex dynamics of proteins. Principal areas of expertise: * Pulsed Fourier Transform and Two Dimensional ESR * High Frequency-High Field (HFHF) ESR * High Resolution ESR Microscopy * Theory and Computational Methods for Modern ESR Activities include: * making resources available to the biomedical community, * publishing results, * running workshops on the new methodologies, * addressing the need to bring these new technologies to other laboratories. electron spin resonance, spectrometer, electron spin resonance spectrometer, structure, dynamics, protein, structural biology technology center has parent organization: Cornell University; New York; USA NIGMS P41GM103521;
NCRR P41RR016292
Free, Freely Available nlx_152669 SCR_001444 SciCrunch Registry ACERT National ESR Center, National Biomedical Center for Advanced Electron Spin Resonance Technology 2026-10-24 12:52:03 1
Center for Integrative Biomedical Computing
 
Resource Report
Resource Website
1+ mentions
Center for Integrative Biomedical Computing (RRID:SCR_001961) CIBC biomedical technology research center, training resource Biomedical technology research center that produces open-source software tools for biomedical image-based modeling, biomedical simulation and estimation, and the visualization of biomedical data. The Center works closely with software users and collaborators in a range of scientific domains to produce user-optimized tools and provides advice, technical support, workshops, and education to enhance user success. Biological projects and collaborations drive their development efforts, all with a single unifying vision: to develop the role of image-based modeling and analysis in biomedical science and clinical practice. The CIBC has a strong, ongoing emphasis on software simulation of bioelectric fields, with clinically oriented collaborations in cardiac defibrillation and the diagnosis/treatment of epilepsy. In addition, the CIBC has expanded in recent years to include applications of statistical shape analysis and three-dimensional visualization to mouse genetics and neuroimaging and applications of image and geometry processing to cell biology. cardiac defibrillation, epilepsy, software, biomedical, image, modeling, simulation, estimation, visualization, computing, informatics, computing and informatics technology center has parent organization: University of Utah; Utah; USA NIGMS P41GM103545 nif-0000-10535 SCR_001961 SciCrunch Registry NIH/NIGMS Center for Integrative Biomedical Computing 2026-10-24 12:52:04 4
Human Mortality Database
 
Resource Report
Resource Website
100+ mentions
Human Mortality Database (RRID:SCR_002370) HMD data or information resource, data set A database providing detailed mortality and population data to those interested in the history of human longevity. For each country, the database includes calculated death rates and life tables by age, time, and sex, along with all of the raw data (vital statistics, census counts, population estimates) used in computing these quantities. Data are presented in a variety of formats with regard to age groups and time periods. The main goal of the database is to document the longevity revolution of the modern era and to facilitate research into its causes and consequences. New data series is continually added to this collection. However, the database is limited by design to populations where death registration and census data are virtually complete, since this type of information is required for the uniform method used to reconstruct historical data series. As a result, the countries and areas included are relatively wealthy and for the most part highly industrialized. The database replaces an earlier NIA-funded project, known as the Berkeley Mortality Database. * Dates of Study: 1751-present * Study Features: Longitudinal, International * Sample Size: 37 countries or areas age, birth, country, demography, health, public health, longevity, longitudinal, international, census data, vital statistics, mortality, population, census, death, FASEB list is listed by: re3data.org
is listed by: Inter-university Consortium for Political and Social Research (ICPSR)
is related to: Human Life-Table Database
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Max Planck Institute for Demographic Research; Mecklenburg-Vorpommern; Germany
Aging NIA R01 AG11552 Free, Registration required, User agreement, Acknowledgement required nif-0000-21197 http://www.humanmortality.de/ SCR_002370 SciCrunch Registry The Human Mortality Database 2026-10-24 12:52:05 238

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