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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core that provides investigators with access to adipose tissue samples from well-characterized subjects. It also assists investigators with analysis of adipose tissue morphology and metabolism, specialized cell and organ culture methods, and analysis of gene and protein expression.
Proper citation: Mid-Atlantic Nutrition Obesity Research Center Biological Mechanisms and Functional Genomics Core (RRID:SCR_015432) Copy
http://bnorc.org/cores/transgenic.html
Core that utilizes investigator-derived DNA constructs or investigator derived (or obtained) genetically modified embryonic stem cells to create founder transgenic organisms that can be used to address questions relevant to obesity, diabetes and nutrition, including questions related to brain control of feeding, metabolism and reward.
Proper citation: Boston Nutrition and Obesity Research Centers Transgenic Core (RRID:SCR_015433) Copy
http://www.medschool.umaryland.edu/norc/Cores/Biostatistics--Medical-Informatics-BMI-Subcore/
Core that provides biostatistical consultation to other investigators who are doing research in the fields of obesity and nutrition at University of Maryland and the Baltimore VA Medical Center. It aims to develop new methods for data collection data from older subjects.
Proper citation: Mid-Atlantic Nutrition Obesity Research Center Biostatistics and Medical Informatics Subcore (RRID:SCR_015434) Copy
http://sph.unc.edu/norc/research-partnerships/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 23,2019. Center that provides bioinformatics and metabolomics support to UNC members for nutrition and obesity-related clinical and translational research.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Research Facilitation Program (RRID:SCR_015480) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/animal-models-core
Core that provides support to investigators who use animal models to study the pathogenesis of cystic fibrosis and who develop gene and other molecular therapies for cystic fibrosis. Specifically, it provides centralized production, care, breeding, genotyping, and quality control of cystic fibrosis mouse and ferret models used by investigators in the Center.
Proper citation: University of Iowa Center for Gene Therapy Animal Model Core (RRID:SCR_015413) Copy
http://cunorc.org/cores/energy-core/
Core facility for University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center. Provides support for measurement of components of energy balance and for assessing consequences of alterations in energy balance. Provides expertise and support for obesity and nutrition related basic, clinical, translational, and transdisciplinary research for NORC investigators and its affiliates. Provides services to assess body composition, bone density, physical fitness, and energy expenditure values in research participants.
Proper citation: University of Colorado Anschutz Medical Campus Nutrition and Obesity Research Center Energy Balance Assessment Core Facility (RRID:SCR_015914) Copy
https://sdrc.stanford.edu/sdrc-research-cores/dgac/home/
Core facility that offers library preparation and sequencing services on a variety of platforms - Illumina HiSeq 4000, MiSeq, HiSeq 2500 and PacBio Sequel - as well as bioinformatics analysis. It can sequence a variety of commercial sample preparation kits as well as custom workflows. DGAC provides access to high throughput sequencing and analysis to researchers at the Stanford Diabetes Research Center.
Proper citation: Stanford Diabetes Research Center Diabetes Genomics Analysis Core (RRID:SCR_016213) Copy
https://github.com/biobakery/MMUPHin
Software R package that implements meta-analysis methods for microbial community profiles. It provides standardized statistical workflows for: a) covariate-controlled batch and study effect adjustment, b) meta-analytic differential abundance testing, and c) unsupervised population structure discovery (both discrete, cluster-based, and continuous gradients). Used to normalize, combine, and analyze multiple independent microbiome datasets using taxonomic or functional abundance profiles.
Proper citation: MMUPHin (RRID:SCR_028853) Copy
https://github.com/cozygene/bisque
Software R toolkit for accurate and efficient estimation of cell composition ('decomposition') from bulk expression data with single-cell information. Used to estimate cell-type proportions in bulk RNA sequencing data by robustly integrating single-cell RNA-seq (scRNA-seq) or single-nucleus RNA-seq (snRNA-seq) information.
Proper citation: Bisque (RRID:SCR_028998) Copy
Centralized knowledge base of the human pancreas for diabetes research. Integrates diverse type 1 diabetes (T1D) datasets with expert-curated knowledge in centralized, open-source data hub. Since users will ultimately be able to contribute their own data, this will be repository for reproducible, collaborative research within the pancreas and T1D realms.
Proper citation: PanKbase (RRID:SCR_026593) Copy
https://github.com/williamslab/ped-sim
Software tool to simulate pedigree structures. Used for simulating relatives that can utilize either sex-specific or sex averaged genetic maps and also either model of crossover interference or traditional Poisson model for inter-crossover distances.
Proper citation: ped-sim (RRID:SCR_026957) Copy
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