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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/MouseLand/facemap
Software toolbox for unsupervised video analysis of rodent behavior.Used for videographic processing of head fixed rodent behavior.
Proper citation: FaceMap (RRID:SCR_021513) Copy
https://github.com/kscottz/SkinnerBox
Software tool for data logging and analysis.
Proper citation: Skinner Box (RRID:SCR_021514) Copy
https://github.com/bonsai-rx/bonsai
Software tool as event based framework for processing and controlling data streams. Open source software tool as visual language for reactive programming.Used for composing reactive and asynchronous data streams coming from video cameras, microphones, electrophysiology systems or data acquisition boards.
Proper citation: Bonsai (RRID:SCR_021512) Copy
https://github.com/cortex-lab/Rigbox
Open source software MATLAB toolbox for running behavioral neuroscience experiments and managing data.Used for probing neurons and behavior. Used for managing behavioral neuroscience experiments and acquiring experiment related data.
Proper citation: Rigbox (RRID:SCR_021517) Copy
Clinical stage company identifying and advancing transformative therapies for people with rare and specialty diseases. Former name was ArTara Therapeutics.
Proper citation: Protara Therapeutics (RRID:SCR_021376) Copy
https://edspace.american.edu/openbehavior/project/ardbark/
Project related to fear conditioning studies.Includes hardware and software tools. Provides Arduino based device for producing naturalistic stimuli which can be integrated with existing commercial operant chambers with few modifications.. Stores custom made .wav files on SD card, interfaces with Med System and plays the .wav files through ceiling mounted speakers.
Proper citation: Ardbark project (RRID:SCR_021494) Copy
https://edspace.american.edu/openbehavior/project/novel-gustometer/
Project related to taste sensory system research in humans on behavioral, electrophysiological and hemodynamic activity levels.Provided system includes hardware and software tools.
Proper citation: Novel Gustometer for Human Taste Research project (RRID:SCR_021495) Copy
https://edspace.american.edu/openbehavior/project/hasra/
Project includes system for individualized training of group housed mice in single pellet reaching task.System allows user to host up to 5 mice in their home environment and automatically administer single pellet reaching test to those animals.Platform for training and assessing skilled reaching in mice with minimal need for experimenter handling.
Proper citation: Home Cage Automated Skilled Reaching Apparatus project (RRID:SCR_021492) Copy
https://github.com/jpgill86/neurotic
Software Python toolbox for interactive characterization in neuroscience.Users can read in variety of file formats for neural data and video, which they can then process, filter, analyze, annotate and plot.Used to review and annotate signal data synchronized with video, performs simple initial analyses including signal filtering and spike detection, supports variety of file formats.Facilitates collaborations by using portable specification for loading and processing data and retrieving data files from online sources.App for Windows, macOS, and Linux to review and annotate electrophysiology data and simultaneously captured video.
Proper citation: neurotic (RRID:SCR_021406) Copy
https://github.com/yorambenshaul/optimouse
Software tool for analysis of mouse position data.Open source software to analyze positions of individual mice, specifically their nose positions, in behavioral arena with the goal of minimizing error.
Proper citation: Optimouse (RRID:SCR_021527) Copy
https://edspace.american.edu/openbehavior/project/diynamic/
Project is related to measurement of complex phenotypes in homecage. Homecage automated open source behavioral testing sytem to enable high throughput 24h testing of many standard operant paradigms. Using Arduino platform and easily sourced inexpensive components system can display light cues and dispense liquid rewards and has nosepoke receptacles with infrared detectors for operant responses, within homecage.Method provided by Dartmouth College scientists.
Proper citation: DIY-NAMIC project (RRID:SCR_021489) Copy
Software tool as macro for SPSS, SAS, and R that conducts observed variable mediation, moderation, and conditional process analysis.Observed variable OLS and logistic regression path analysis modeling tool. Used for estimating direct and indirect effects in single and multiple mediator models parallel and serial, two and three way interactions in moderation models along with simple slopes and regions of significance for probing interactions, and conditional indirect effects in moderated mediation models with single or multiple mediators or moderators. Operates on Windows and Mac versions of SPSS and SAS.
Proper citation: PROCESS (RRID:SCR_021369) Copy
https://github.com/pascalkieslich/mousetrap-os
Integrated, open source mouse tracking software package.Software plugin to record and analyze mouse movements in computerized lab experiments.Software plugin provides two items that implement mouse tracking in OpenSesame.
Proper citation: Mousetrap (RRID:SCR_021523) Copy
https://edspace.american.edu/openbehavior/project/captouch/
Project related to study learning and memory in preclinical research.Included tracking system for object recognition tasks provides standardization across experiments and labs.Automates scoring process using capacitive sensors, while providing validated 3D-printed objects in order to standardize object recognition to study learning and memory in preclinical research.Used for accurate measurement of interaction time during object recognition tasks.
Proper citation: CapTouch project (RRID:SCR_021488) Copy
http://www.genepaint.org/MapE15_5_01.htm
Abbreviated reference atlas for the Embryonic 15.5 post conception day mouse. All sections were nissl stained and digitized. To assist in the initial identification of sites of gene expression sites, maps of brains are available for E15.5, P7 and the adult. These maps depict the boundaries of major brain regions (cortex, thalamus, striatum, globus pallidus, ventral striatum, septum, basal forebrain, hippocampus, midbrain, pons, medulla, cerebellum) and also show the more prominent nerve tracts. Maps are most efficiently used by placing the window depicting the map of interest next to the gene expression image. Browsing between planes of sectioning is permitted thus allowing the most appropriate plane to be selected. The annotation of anatomical details such as brain nuclei is currently beyond the scope of the GenePaint database. Hence, such information on the anatomy of the brain and embryo should be obtained from published atlases of mouse anatomy (Kaufman, 1995; Paxinos and Franklin, 2001; Jacobowitz and Abbott, 1997; Schambra et al., 1992; Valverde1998).
Proper citation: GenePaint E15 Atlas (RRID:SCR_002786) Copy
https://www.cincinnatichildrens.org/research/cores/biobank
Provides access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research. Services include biospecimen storage, serum and plasma processing, preparation of kits for sample collection and shipping, automated DNA/RNA extraction from blood, saliva, tissue and other materials, biofluid collection, processing and storage, tissue collection, processing and storage.Home to Better Outcomes for Children (BofC) biorepository.
Proper citation: Cincinnati Biobank Core Facility (RRID:SCR_004281) Copy
http://niftyrec.scienceontheweb.net/
Software toolbox that includes reconstruction tools for emission and transmission imaging modalities, including Single Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), cone-beam X-Ray CT and parallel-beam X-Ray CT. At the core of NiftyRec are efficient, GPU accelerated, projection, back-projection and iterative reconstruction algorithms. The easy to use Matlab and Python interfaces of NiftyRec enable fast prototyping and development of reconstruction algorithms. NiftyRec includes standard iterative reconstruction algorithms such as Maximum Likelihood Expectation Maximisation (MLEM), Ordered Subsets Expectation Maximisation (OSEM) and One Step Late Maximum A Posteriori Expectation Maximisation (OSL-MAPEM), for multiple imaging modalities.
Proper citation: NiftyRec (RRID:SCR_002499) Copy
http://www.duke.edu/web/gpcr-assay/index.html
Describes data from and access to permanent cell lines containing beta-arrestin fluorescent protein biosensors. This assay Bank provides plasmids, cells lines, and resulting data to the NIDA/NIH funded research community in order to better understand and combat addiction.
Proper citation: Addiction Research GPCR Assay Bank (RRID:SCR_002895) Copy
Group of 10 academic laboratories provide pancreatic islets of cGMP-quality to eligible investigators for use in FDA approved, IRB-approved transplantation protocols in which isolated human islets are transplanted into qualified patients afflicted with type 1 diabetes mellitus; optimize the harvest, purification, function, storage, and shipment of islets while developing tests that characterize the quality and predict the effectiveness of islets transplanted into patients with diabetes mellitus; and provide pancreatic islets for basic science studies. The centers are electronically linked through an Administrative and Bioinformatics Coordinating Center (ABCC). The ABCC manages a system with objectively defined criteria that establishes the order of priority for islet distribution. It also provides database and other informatics to track the utilization of pancreata and all distributed clinical grade islets for transplant and basic research, and supports the Islet Cell Resource Centers Consortium so that the research community has a single entry point to the program. Qualified researchers from domestic institutions may request islets by submitting a written application to the director of the ABCC. The ICRs will distribute Islets as appropriate for either clinical or basic science protocol use to eligible investigators who have received a favorable review and subsequent approval by the ICR Steering Committee (SC). The Administrative and Bioinformatics Coordinating Center (ABCC) manages the distribution according to a priority list. The ABCC will give preference to investigators who have peer-reviewed, NIH-funded research support.
Proper citation: Islet Cell Resource Centers (RRID:SCR_002806) Copy
Collaborative project to bring together biochemical pathway databases and research communities focused on plant metabolism. Used to build broad network of plant metabolic pathway databases. Central feature of PMN is PlantCyc, comprehensive plant biochemical pathway database, containing curated information from literature and computational analyses about genes, enzymes, compounds, reactions, and pathways involved in primary and secondary metabolism.
Proper citation: Plant Metabolic Network (RRID:SCR_002888) Copy
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