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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
HOMOZYGOSITYMAPPER
 
Resource Report
Resource Website
100+ mentions
HOMOZYGOSITYMAPPER (RRID:SCR_001714) HomozygosityMapper analysis service resource, data analysis service, production service resource, service resource A web-based approach of homozygosity mapping that can handle tens of thousands markers. User can upload their own SNP genotype files to the database. Intuitive graphic interface is provided to view the homozygous stretches, with the ability of zooming into single chromosomes or user-defined chromosome regions. The underlying genotypes in all samples are displayed. The software is also integrated with our candidate gene search engine, GeneDistiller, so that users can interactively determine the most promising gene. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, genotype, homozygosity score, homozygosity, bio.tools, FASEB list is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Charite - Universitatsmedizin Berlin; Berlin; Germany
PMID:19465395 Free, Freely Available nlx_154069, biotools:homozygositymapper, OMICS_00123 https://bio.tools/homozygositymapper SCR_001714 2026-09-19 12:56:31 125
WebGeSTer DB
 
Resource Report
Resource Website
1+ mentions
WebGeSTer DB (RRID:SCR_002165) WebGeSTer DB data or information resource, database Database of intrinsic terminators of transcription that is comprized of >2,200,000 bacterial terminators identified from a total of 2036 chromosomes and 1508 plasmids. Information about structural parameters of individual terminators such as sequence, length of stem and loop, mismatches and gaps, U-trail, genomic coordinates and gene name and accession number is available in both tabular form and as a composite figure. Summary statistics for terminator profiles of whole genome can be also obtained. Raw data files for individual genomes can be downloaded (.zip files) for detailed investigations. Data is organized into different tiers such that users can fine-tune their search by entering name of the species, or taxon ID or genomes with a certain number of terminators. To visualize the occurrence of the terminators, an interactive map, with the resolution to single gene level, has been developed. genome, terminator, transcription, plasmid, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20972211 THIS RESOURCE IS NO LONGER IN SERVICE biotools:webgester_db, OMICS_01862 https://bio.tools/webgester_db SCR_002165 WebGesTer Database, Web Genome Scannner for Terminators Database, WebGeSTer DB - A Transcription Terminator Database 2026-09-19 12:56:34 5
PubGene
 
Resource Report
Resource Website
10+ mentions
PubGene (RRID:SCR_002119) data or information resource, database It helps users retrieve information on genes and proteins. The underlying structure of PubGene can be viewed as a gene-centric database. Gene and protein names are cross-referenced to each other and to terms that are relevant to understanding their biological function, importance in disease and relationship to chemical substances. The result is a literature network organizing information in a form that is easy to navigate. gene, information, protein, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is parent organization of: Coremine Medical
Free, Freely Available biotools:pubgene, nif-0000-20908 https://bio.tools/pubgene SCR_002119 PubGene 2026-09-19 12:56:33 39
EchoBASE
 
Resource Report
Resource Website
1+ mentions
EchoBASE (RRID:SCR_002430) EchoBASE data or information resource, database A database that curates new experimental and bioinformatic information about the genes and gene products of the model bacterium Escherichia coli K-12 strain MG1655. It has been created to integrate information from post-genomic experiments into a single resource with the aim of providing functional predictions for the 1500 or so gene products for which we have no knowledge of their physiological function. While EchoBASE provides a basic annotation of the genome, taken from other databases, its novelty is in the curation of post-genomic experiments and their linkage to genes of unknown function. Experiments published on E. coli are curated to one of two levels. Papers dealing with the determination of function of a single gene are briefly described, while larger dataset are actually included in the database and can be searched and manipulated. This includes data for proteomics studies, protein-protein interaction studies, microarray data, functional genomic approaches (looking at multiple deletion strains for novel phenotypes) and a wide range of predictions that come out of in silico bioinformatic approaches. The aim of the database is to provide hypothesis for the functions of uncharacterized gene products that may be used by the E. coli research community to further our knowledge of this model bacterium. gene, bio.tools is listed by: bio.tools
is listed by: Debian
GlaxoSmithKline ;
BBSRC
PMID:15608209 nif-0000-02781, biotools:echobase, r3d100011646 https://bio.tools/echobase, https://doi.org/10.17616/R38W6H SCR_002430 EchoBASE: an integrated post-genomic database for Escherichia coli 2026-09-19 12:56:36 6
Autophagy Database
 
Resource Report
Resource Website
10+ mentions
Autophagy Database (RRID:SCR_002671) Autophagy DB, AutophagyDB data or information resource, database Database that provides basic, up-to-date information on relevant literature, and a list of autophagy-related proteins and their homologs in eukaryotes. autophagy, protein, homolog, ortholog, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tokyo; Tokyo; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:20972215 Free, Available for download, Freely available OMICS_03306, biotools:the_autophagy_database, r3d100012565 https://bio.tools/the_autophagy_database, https://doi.org/10.17616/R3J786 SCR_002671 2026-09-19 12:56:36 22
DOMINE: Database of Protein Interactions
 
Resource Report
Resource Website
1+ mentions
DOMINE: Database of Protein Interactions (RRID:SCR_002399) DOMINE data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 13,2026. Database of known and predicted protein domain (domain-domain) interactions containing interactions inferred from PDB entries, and those that are predicted by 8 different computational approaches using Pfam domain definitions. DOMINE contains a total of 26,219 domain-domain interactions (among 5,410 domains) out of which 6,634 are inferred from PDB entries, and 21,620 are predicted by at least one computational approach. Of the 21,620 computational predictions, 2,989 interactions are high-confidence predictions (HCPs), 2,537 interactions are medium-confidence predictions (MCPs), and the remaining 16,094 are low-confidence predictions (LCPs). (May 2014) domain-domain interaction, prediction, protein domain, interaction, protein domain interaction, protein, domain, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: Pfam
has parent organization: University of Texas at Dallas; Texas; USA
PMID:21113022
PMID:17913741
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01906, nif-0000-02758, biotools:domine https://bio.tools/domine SCR_002399 Database of Protein Domain Interactions 2026-09-19 12:56:36 2
VIPERdb
 
Resource Report
Resource Website
50+ mentions
VIPERdb (RRID:SCR_002853) data or information resource, database Database for icosahedral virus capsid structures. The emphasis of the resource is on providing data from structural and computational analyses on these systems, as well as high quality renderings for visual exploration. In addition, all virus capsids are placed in a single icosahedral orientation convention, facilitating comparison between different structures. The web site includes powerful search utilities , links to other relevant databases, background information on virus capsid structure, and useful database interface tools. It is an information source for the analysis of high resolution virus structures. VIPERdb is a one-stop site dedicated to helping users around the world examine the many icosahedral virus structures contained within the Protein Data Bank (PDB) by providing them with an easy to use database containing current data and a variety of analytical tools. Sponsors: VIPERdb is funded by the NIH., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. exploration, analysis, capsid, computational, convention, database, icosahedral, structural, structure, system, virus, visual, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Scripps Research Institute
PMID:33313778
PMID:30265627
Free, Freely available nif-0000-25311, r3d100012362, nif-0000-03630, biotools:viperdb, SCR_007970 https://bio.tools/viperdb, https://doi.org/10.17616/R3HT0Q SCR_002853 Virus Particle ExploreR 2026-09-19 12:56:37 59
Human Gene Connectome Server
 
Resource Report
Resource Website
1+ mentions
Human Gene Connectome Server (RRID:SCR_002627) HGCS analysis service resource, data analysis service, production service resource, service resource An interactive web server that enables researchers to prioritize any list of genes by their biological proximity to defined core genes (i.e. genes that are known to be associated with the phenotype), and to predict novel gene pathways. gene, disease, phenotype, genome, connectome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Human Gene Connectome
PMID:23509278 Free nlx_156049, biotools:hgcs https://bio.tools/hgcs SCR_002627 2026-09-19 12:56:36 8
SNPAAMapper
 
Resource Report
Resource Website
SNPAAMapper (RRID:SCR_002012) SNPAAMapper data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2025. A downstream variant annotation program that can effectively classify variants by region (e.g. exon, intron, etc), predict amino acid change type (e.g. synonymous, non-synonymous mutation, etc), and prioritize mutation effects (e.g. CDS versus 5?UTR, etc). Major features: * The pipeline accepts the VCF (Variant Call Format) input file in tab-delimited format and processes the vcf input file containing all cases (G5, lowFreq, and novel) * The variant mapping step has the option of letting users select whether they want to report the bp distance between each identified intron variant and its nearby exon * The pipeline can deal with VCF files called by different SAMTools versions (0.1.18 and older ones) and also offers flexibility in dealing with vcf input files generated using SAMTools with two or three samples * The spreadsheet result file contains full protein sequences for both ref and alt alleles, which makes it easier for downstream protein structure/function analysis tools to take single nucleotide polymorphism, amino acid, variant, annotation, exon, intron, mutation, next-generation sequencing, perl, downstream analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Michigan Medical School; Michigan; USA
PMID:24250114 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01922, biotools:snpaamapper https://bio.tools/snpaamapper SCR_002012 SNPAAMapper - A SNP Amino Acid Mapping tool 2026-09-19 12:55:50 0
skewer
 
Resource Report
Resource Website
10+ mentions
skewer (RRID:SCR_001151) skewer data processing software, software application, software resource Software program for adapter trimming that is specially designed for processing Illumina paired-end sequences. illumina, unix/linux, c++, adapter trimming, paired-end, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24925680 Free, Available for download, Freely available OMICS_02106, biotools:skewer https://bio.tools/skewer, https://sources.debian.org/src/skewer/, https://github.com/relipmoc/skewer SCR_001151 skewer - A fast and sensitive adapter trimmer for illumina paired-end sequences 2026-09-19 12:55:49 14
Mspire-Simulator
 
Resource Report
Resource Website
1+ mentions
Mspire-Simulator (RRID:SCR_001431) simulation software, software application, software resource, standalone software A free, open-source shotgun proteomic simulator that goes beyond previous simulation attempts by generating LC-MS features with realistic m/z and intensity variance along with other noise components. standalone software, shotgun, proteomic, simulation software, bio.tools uses: mzML
is listed by: OMICtools
is listed by: GitHub
is listed by: bio.tools
is listed by: Debian
has parent organization: Brigham Young University; Utah; USA
PMID:24090032 Free, Freely Available biotools:mspire-simulator, OMICS_03359 https://bio.tools/mspire-simulator SCR_001431 2026-09-19 12:55:50 1
HTqPCR
 
Resource Report
Resource Website
50+ mentions
HTqPCR (RRID:SCR_003375) HTqPCR data processing software, software application, software resource Software package for the analysis of Ct values from high throughput quantitative real-time PCR (qPCR) assays across multiple conditions or replicates. The input data can be from spatially-defined formats such ABI TaqMan Low Density Arrays or OpenArray; LightCycler from Roche Applied Science; the CFX plates from Bio-Rad Laboratories; conventional 96- or 384-well plates; or microfluidic devices such as the Dynamic Arrays from Fluidigm Corporation. HTqPCR handles data loading, quality assessment, normalization, visualization and parametric or non-parametric testing for statistical significance in Ct values between features (e.g. genes, microRNAs). data import, differential expression, gene expression, microtitre plate assay, multiple comparison, preprocessing, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
PMID:19808880 Free, Available for download, Freely available biotools:htqpcr, OMICS_02314 https://bio.tools/htqpcr SCR_003375 HTqPCR - Automated analysis of high-throughput qPCR data 2026-09-19 12:55:52 74
NanoStringNorm
 
Resource Report
Resource Website
100+ mentions
NanoStringNorm (RRID:SCR_003382) NanoStringNorm data processing software, software application, software resource Software package for normalizing, diagnostics and visualization of NanoString nCounter data. Key features include an extensible environment for method comparison and new algorithm development, integrated gene and sample diagnostics, and facilitated downstream statistical analysis. normalization, nanostring ncounter, mirna, mrna, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Ontario Institute for Cancer Research
PMID:22513995 Free, Available for download, Freely available OMICS_02308, biotools:nanostringnorm https://www.rdocumentation.org/packages/NanoStringNorm/versions/1.2.1.1/topics/NanoStringNorm SCR_003382 NanoStringNorm: Normalize NanoString miRNA and mRNA data 2026-09-19 12:55:52 137
IMG System
 
Resource Report
Resource Website
100+ mentions
IMG System (RRID:SCR_002965) IMG, IMG/M data or information resource, portal Resource for analysis and annotation of genome and metagenome datasets in comprehensive comparative context. IMG provides users with tools for analyzing publicly available genome datasets and metagenome datasets. microbiome, microbial genetics, genome and metagenome datasets analysis, genome and metagenome datasets, genome, metagenomics, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: Human Microbiome Project
has parent organization: DOE Joint Genome Institute
PMID:17932063
PMID:22086953
Free, Freely available nif-0000-03010, OMICS_01478, SCR_014605, biotools:img_m http://img.jgi.doe.gov/m, https://bio.tools/img_m SCR_002965 Integrated Microbial Genomes System 2026-09-19 12:55:52 212
SeqExpress
 
Resource Report
Resource Website
SeqExpress (RRID:SCR_007075) data processing software, software application, software resource A comprehensive analysis and visualization software package for gene expression experiments that provides: a number of clustering and analysis techniques; integrated gene expression and analysis result visualizations, integration with the Gene Expression Omnibus; and an optional data sharing architecture. GO is used to assign functional enrichment scores to clusters, using a combination of specially developed techniques and general statistical methods. These results can be explored using the in built ontology browsing tool or through the generated web pages. SeqExpress also supports numerous data transformation, projection, visualization, file export/import, searching, integration (with R), and clustering options. gene, gene expression, function, analysis, visualization, statistical analysis, windows, c#, gene function, chromosome location, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Gene Expression Omnibus
PMID:14988116 Free nlx_149285, biotools:seqexpress https://bio.tools/seqexpress SCR_007075 2026-09-19 12:55:56 0
RIKEN integrated database of mammals
 
Resource Report
Resource Website
RIKEN integrated database of mammals (RRID:SCR_006890) RIKEN integrated database of mammals data or information resource, database, portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 16, 2019.
A database that integrates not only RIKEN''''s original large-scale mammalian databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists'''' Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
integration, network, standardization, biomedical, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Functional Annotation of the Mammalian Genome
is related to: Cerebellar Development Transcriptome Database
is related to: Ensembl
is related to: Mouse Genome Informatics (MGI)
is related to: OBO
has parent organization: RIKEN Yokohama Institute; Kanagawa; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:21076152 THIS RESOURCE IS NO LONGER IN SERVICE nlx_151886, biotools:riken https://bio.tools/riken SCR_006890 2026-09-19 12:55:56 0
epigenomix
 
Resource Report
Resource Website
1+ mentions
epigenomix (RRID:SCR_006407) epigenomix data processing software, software application, software resource Software package for the integrative analysis of microarray based gene expression and histone modification data obtained by ChIP-seq. The package provides methods for data preprocessing and matching as well as methods for fitting bayesian mixture models in order to detect genes with differences in both data types. epigenetic, gene expression, microarray, histone modification, chip-seq, classification, differential expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24403540 GNU Lesser General Public License, v3 biotools:epigenomix, OMICS_02205 https://bio.tools/epigenomix SCR_006407 epigenomix - Epigenetic and gene expression data normalization and integration with mixture models 2026-09-19 12:55:55 2
SOAPaligner/soap2
 
Resource Report
Resource Website
100+ mentions
SOAPaligner/soap2 (RRID:SCR_005503) SOAPaligner, SOAP2 data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Updated version of SOAP software for short oligonucleotide alignment that features in super fast and accurate alignment for huge amounts of short reads generated by Illumina/Solexa Genome Analyzer., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. next generation sequencing, alignment, short read, oligonucleotide, single-read, pair-end, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SOAP
PMID:19497933
DOI:10.1093/bioinformatics/btn025
THIS RESOURCE IS NO LONGER IN SERVICE biotools:soap2 https://bio.tools/soap2, https://sources.debian.org/src/soapaligner/ SCR_005503 2026-09-19 12:55:54 325
Pedigree-Draw
 
Resource Report
Resource Website
1+ mentions
Pedigree-Draw (RRID:SCR_008302) commercial organization, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Software application for pedigree drawing (entry from Genetic Analysis Software) gene, genetic, genomic, macos, bio.tools is listed by: Genetic Analysis Software
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154520, OMICS_00213, SCR_010795 SCR_008302 PEDIGREE/DRAW 2026-09-19 12:55:57 1
COILS: Prediction of Coiled Coil Regions in Proteins
 
Resource Report
Resource Website
100+ mentions
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) data processing software, software application, software resource COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1126/science.252.5009.1162 biotools:ncoils, OMICS_07850, nif-0000-30263 https://bio.tools/ncoils, https://sources.debian.org/src/ncoils/ https://sources.debian.org/src/ncoils/ SCR_008440 COILS Server 2026-09-19 12:55:57 169

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