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http://www.roslin.ed.ac.uk/about-roslin/

The world''s largest collection of tick cell lines, enabling scientists to carry out advanced research. This biobank is establishing a collection of all the continuous cell lines derived from ixodid and argasid ticks of medical and veterinary importance available worldwide now and in future. Ticks are blood feeding arthropods which transmit many human and animal diseases. Research into prevention and cure of these diseases, which are caused by viruses, bacteria and protozoa, is greatly assisted by the use of cell culture systems which enable study of both how tick cells function, and how and why ticks transmit these disease-causing pathogens. Cell lines will always be shipped to recipient laboratories as growing cultures, since we cannot guarantee successful resuscitation of frozen stabilates. Tick cells in culture can tolerate the range of temperatures experienced during transit by air for up to a week. Training: We will provide training in tick cell line care and maintenance. This is an essential component of successful transfer of tick cells to, and their establishment in, laboratories with little or no previous experience of tick cell culture. Recipient scientists (preferably the person who will actually look after the cells) can visit the biobank for between 2 days and 2 weeks, depending on their level of previous experience, to be trained in the specific approach and methods for tick cell cultivation. Establishment of new cell lines: In response to requests and on receipt of suitable starting material (engorged female or moulting nymphal ticks), we will attempt to establish new cell lines from tick species or strains which are not already represented in the collection. Deposition of new tick cell lines: We invite researchers anywhere in the world who have established new tick cell lines to deposit samples for safekeeping free of charge and, if requested, for distribution alongside the existing biobank portfolio.

Proper citation: Roslin Wellcome Trust Tick Cell Biobank (RRID:SCR_004228) Copy   

•   Source: SciCrunch Registry

http://www.nitrc.org/projects/unc_brain_atlas

Human brain atlases for adult, pediatric and elderly populations, by iterative joint deformable registration of training datasets into a single unbiased average image. Atlases packages include T1-weighted images, tissue priors (WM,GM,CSF), lobar parcellation maps and subcortical structures. Current available atlases: * Adult atlas: Symmetric atlas generated from 50+ healthy adult subjects (20-59 year old). * UNC-MNI Pediatric 1-year-old atlas: Symmetric atlas generated from 104 1-year-old subjects, combining children at high familial risk of autism and controls. * Pediatric 4-year-old atlas: Symmetric atlas generated from 10 4-year-old healthy subjects. * Elderly atlas: Atlas generated from 27 healthy elderly subjects (60+ years old). Additional information and acknowledgment for their usage can be found by clicking on the release notes.

Proper citation: UNC Human Brain Atlas (RRID:SCR_002606) Copy   

•   Source: SciCrunch Registry

http://www.cryo-save.com/

Stem cell banking is a unique opportunity to store the precious building blocks of the human body; cord blood, cord tissue and fat tissue are just some sources of stem cells ready to provide the foundation for more than 70 treatments of blood, blood related diseases and future applications in regenerative medicine. To not consider the storage or donation of these precious stem cells could be a missed opportunity! Cryo-Save is officially recognized as the largest family stem cell bank in Europe. With more than 180,000 samples stored and four fully-owned storage facilities throughout the world, Cryo-Save has over ten years'' experience and state-of-the-art technical know-how, providing the basis for a strong and reliable organization. An ethical approach, scientific professionalism and customer-focused care are the core elements of our daily activities, as we strive to be an active player in life-science development in over 40 countries. Our company was established in 2000, is headquartered in the Netherlands and successfully active in 40 countries across four continents. We are officially accredited by the regulatory authorities and set the highest quality standards in everything we do. We follow a dual storage system, meaning that the stem cells are stored independently in two separate storage tanks within our state-of-the-art facility. Our dedication to research in collaboration with universities, physicians and stem cell scientists has put us at the forefront of technological developments.

Proper citation: Cryo-Save (RRID:SCR_004504) Copy   

•   Source: SciCrunch Registry

http://discover.nci.nih.gov/gominer/

GoMiner is a tool for biological interpretation of "omic" data including data from gene expression microarrays. Omic experiments often generate lists of dozens or hundreds of genes that differ in expression between samples, raising the question, What does it all mean biologically? To answer this question, GoMiner leverages the Gene Ontology (GO) to identify the biological processes, functions and components represented in these lists. Instead of analyzing microarray results with a gene-by-gene approach, GoMiner classifies the genes into biologically coherent categories and assesses these categories. The insights gained through GoMiner can generate hypotheses to guide additional research. GoMiner displays the genes within the framework of the Gene Ontology hierarchy in two ways: * In the form of a tree, similar to that in AmiGO * In the form of a "Directed Acyclic Graph" (DAG) The program also provides: * Quantitative and statistical analysis * Seamless integration with important public databases GoMiner uses the databases provided by the GO Consortium. These databases combine information from a number of different consortium participants, include information from many different organisms and data sources, and are referenced using a variety of different gene product identification approaches.

Proper citation: GoMiner (RRID:SCR_002360) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/MHSCB/index.aspx

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. Stem cell research, particularly human embryonic stem cell (hESC) research, holds tremendous promise to discover therapeutic options and perhaps cures for insidious diseases such as cancer, juvenile diabetes, Alzheimer's and Parkinson's. The Massachusetts Human Stem Cell Bank provides the biomedical research community with expertly maintained human ES (hES) and reprogrammed (iPS) cell lines to facilitate studies into the properties and potential therapeutic applications of pluripotent stem cells. The Bank cultures, characterizes and distributes quality controlled hES and iPS cell lines derived in Massachusetts and beyond. The Bank is a 15,000 square foot facility that contains research and training space for visiting investigators. In addition, the Education and Training division provides technical training and programs to educate the community.

Proper citation: Massachusetts Human Stem Cell Bank (RRID:SCR_004141) Copy   

•   Source: SciCrunch Registry

http://cvr.yorku.ca/home/

The Centre for Vision Research focuses on interdisciplinary research into human and machine vision and visual processes, into vision's interactions with other senses and with motor and cognitive processes, and in applications such as visually-guided robotics or clinical diagnosis and treatment. The Centre for Vision Research includes the following major research themes: - Human Visual Performance - Visual Human-Computer Interaction, Graphics and Virtual Reality - Visual Psychophysics - Eye Movements and Hand-Eye Coordination - Computational Modeling and Computer Vision - Electrophysiology - Clinical and Developmental Studies - Brain Imaging

Proper citation: Centre for Vision Research (RRID:SCR_002879) Copy   

•   Source: SciCrunch Registry

http://www.cellbank.org.uk/

This is a facility for UK-based research into leukemia and other related disorders. The Bank contains viable cells and DNA from children diagnosed with acute leukemia. (diagnostic, treatment and relapse samples) and also HLA- typed normal cord blood donations. Samples can only be obtained from the Cell Bank for approved peer-reviewed and fully costed research projects. To view further information about the Cell Bank, or for instruction on how to apply for samples, please register.

Proper citation: Childhood Leukaemia Cell Bank (RRID:SCR_004135) Copy   

•   Source: SciCrunch Registry

http://www.jgi.doe.gov/

Institute to advance genomics in support of the DOE missions related to clean energy generation and environmental characterization and cleanup. Supported by the DOE Office of Science, the DOE JGI unites the expertise at Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, and the HudsonAlpha Institute for Biotechnology. The facility provides integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to these challenges.

Proper citation: DOE Joint Genome Institute (RRID:SCR_003045) Copy   

•   Source: SciCrunch Registry

http://www.focusonmcl.org/

The Lymphoma Research Foundation (LRF), in collaboration with American Type Culture Collection (ATCC), has created a Mantle Cell Lymphoma (MCL) Cell Bank. The Cell Bank is a collection of various MCL lines created by scientists from all over the world. The idea for the Cell Bank was generated by the scientists that make up the MCL Consortium (MCLC). It was created to provide a single, centralized location where scientists can easily acquire high-quality, well-characterized MCL cell lines in an effort to accelerate discoveries in MCL. LRF has acquired 8 different MCL cell lines (July 2010): Mino, Z-138, JVM-2, JVM-13, REC-1, NCEB-1, JeKo-1, and Maver-1. The Cell Bank is chaired by Dr. Owen O''Connor of New York University Langone Medical Center and is housed at ATCC, the world''s largest biological resource center and the most comprehensive source of reference cultures and reagents used by researchers in the academic and industry laboratories. The Cell Bank was made possible by the scientists who generously agreed to share their resources, including, Dr. Elias Campo, Dr. Zeev Estrov, Dr. Richard Ford, Dr. Junia Melo and Dr. Alberto Zamo.

Proper citation: Mantle Cell Lymphoma Cell Bank (RRID:SCR_004379) Copy   

•   Source: SciCrunch Registry

http://www.stanford.edu/group/nolan/retroviral_systems/phx.html

A second-generation retrovirus producer lines for the generation of helper free ecotropic and amphotropic retroviruses. The lines are based on the 293T cell line (a human embryonic kidney line transformed with adenovirus E1a and carrying a temperature sensitive T antigen co-selected with neomycin). The unique feature of this cell line is that it is highly transfectable with either calcium phosphate mediated transfection or lipid-based transfection protocols-- up to 50% or higher of cells can be transiently transfected. The lines were created by placing into 293T cells constructs capable of producing gag-pol, and envelope protein for ecotropic and amphotropic viruses. The lines offered advantages over previous stable systems in that virus can be produced in just a few days. Academic and non-profit laboratories may obtain the Phoenix cells from either Allele Biotechnology or the National Gene Vector Bank. The vectors may be obtained from Addgene. They are no longer distributing these reagents from the lab.

Proper citation: Phoenix (RRID:SCR_003163) Copy   

•   Source: SciCrunch Registry

http://www.fda.gov/drugs/developmentapprovalprocess/drugdevelopmenttoolsqualificationprogram/default.htm

To support Drug Development Tools development efforts, FDA established qualification programs for animal models for use under Animal Rule, biomarkers, and clinical outcome assessments. DDTs are methods, materials, or measures that have potential to facilitate drug development. Examples of DDTs may include, but are not limited to biomarker2 used for clinical trial enrichment, clinical outcome assessment used to evaluate clinical benefit, and animal model used for efficacy testing of medical countermeasures under regulations commonly referred to as Animal Rule3.

Proper citation: Drug Development Tools Qualification Programs (RRID:SCR_003714) Copy   

•   Source: SciCrunch Registry

http://www.cryolab.com

A US sperm bank that offers superior donor sperm and sperm banking services, including sperm storage and embryo storage. We provide the highest quality in the industry as one of the few sperm banks fully accredited by the American Association of Tissue Banks (AATB). Cryogenic Laboratories is fully compliant with FDA regulations. Extensive donor Information is downloaded FREE for ALL sperm donors. Searching for a donor is fun, easy and free of charge. Most other sperm banks require you to pay for each donor information product you view. So look and listen for free 24/7. Childhood photos, audio clips, medical and personal profiles are all free. Monthly specials are also there to make the process easier.

Proper citation: Cryogenic Laboratories, Inc (RRID:SCR_003558) Copy   

•   Source: SciCrunch Registry

http://www.jainlab.org/downloads.html

Automatic software program for microarray image quantification.

Proper citation: UCSF Spot (RRID:SCR_002985) Copy   

•   Source: SciCrunch Registry

http://lab.rockefeller.edu/casanova/HGC

Data set containing a gene-specific connectome file for each human gene and computer programs for ranking lists of genes within a gene-specific connectome, clustering and plotting the genes by the functional genomic alignment (FGA) approach, and generating gene-specific connectomes. The programs were developed and tested on Mac and Linux systems. The external software required for running these programs is open-source and free of charge. The HGC is the set of all biologically plausible routes, distances, and degrees of separation between all pairs of human genes. A gene-specific connectome contains the set of all available human genes sorted on the basis of their predicted biological proximity to the specific gene of interest. The HGC is a powerful approach for human genotype-phenotype high-throughput studies, for which it can be used to rank any list of genes within a gene-specific connectome for an experimentally validated core gene. Functional genomic alignment (FGA) is equivalent to traditional multiple sequence alignment (MSA), except that it clusters genes in trees on the basis of the functional biological distance between them predicted by HGC, rather than on the basis of molecular evolutionary genetic distance. This method is therefore more suitable for disease and phenotypic studies.

Proper citation: Human Gene Connectome (RRID:SCR_002628) Copy   

•   Source: SciCrunch Registry

http://ccr.coriell.org/Sections/Collections/LMS/?SsId=17

The Leiomyosarcoma Cell and DNA Repository has been established with an award from the National Leiomyosarcoma Foundation. This foundation provides leadership in supporting research of Leiomyosarcoma, improving treatment outcomes of those affected by this disease as well as fostering awareness in the medical community and general public. The resources available include highly-characterized, viable, and contaminant-free cell cultures and high quality, well-characterized DNA samples derived from these cultures, both subjected to rigorous quality control. Leiomyosarcoma is a rare form of cancer, which affects about four people in every million. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body. Presently there is no cure, only remission if it can be attained, and this rare cancer can reappear anywhere at any time. Because of its rarity, few doctors know how to treat it and it attracts very little research. Cell cultures or DNA are distributed only to qualified professional persons who are associated with recognized research, medical, educational, or industrial organizations engaged in health-related research or health delivery. Before cell cultures or DNA samples can be shipped, the principal investigator must sign an ASSURANCE FORM (Material Transfer Agreement) detailing the terms and conditions of sale. This agreement must be renewed annually. In addition, before receiving lymphoblast or other virus-transformed cell cultures users should read the MINIMUM SAFETY GUIDELINES RECOMMENDED FOR WORKING WITH HUMAN CELL CULTURES.

Proper citation: Leiomyosarcoma Cell and DNA Repository (RRID:SCR_004686) Copy   

•   Source: SciCrunch Registry

http://www.crcjussieu.fr/crc/index.php

Organization focusing on the regulation of important functions and the roles of the deregulation of these functions in the genesis and progression of diseases. Nineteen teams are structure in 2 departments, Physiology, Metabolism, Differenciation and Immunology, Cancer, Inflammation. This 2 departments are joined by a Therapeutic Innovations coordinated by a team manager. Through a strong synergism between scientists, clinicians and industry, the CRC has created the means of success of translational research. Several teams are involved in innovation in various fields such as imaging, identifications of genetic, protein or cellular prognostic markers, the production of molecules (monoclonal antibody) or generation of cells (dendritic cells or macrophage) for therapeutic use. The CRC has developed important core facilities including a modern animal facility with a transgenic service, a small animals imaging platform, a core facility for in vivo and ex vivo studies of renal functions, an ex vivo cell imaging facility with a confocal microscopy service, flow cytometry, electron microscopy and laser micro dissection. These facilities under the management of highly competent scientists and engineers work for the transfer of competence toward the students and ensures the continued formation through regular organization of scientific day meetings. The CRC participates in the research and academic training. On the campus is located the faculty of medicine Paris Descartes, the Pierre and Marie Curie Institute of Doctoral training and the school of physiology and pathophysiology. About a hundred PhD students belonging to 8 different Doctoral Schools are hosted in 36 doctoral training teams. Students from technical, bachelor and masters levels are also being trained. In addition, young pupils from secondary and high school participate regularly in the programs for initiation to research conceptions and technology. Seminars as well as meetings at national and European levels and scientific debates on various important contemporary topics, and open-door programs are conducted regularly in the Center.

Proper citation: Cordelier Research Center (RRID:SCR_005775) Copy   

•   Source: SciCrunch Registry

http://bioinformatics.biol.rug.nl/standalone/fiva/

Functional Information Viewer and Analyzer (FIVA) aids researchers in the prokaryotic community to quickly identify relevant biological processes following transcriptome analysis. Our software is able to assist in functional profiling of large sets of genes and generates a comprehensive overview of affected biological processes. Currently, seven different modules containing functional information have been implemented: (i) gene regulatory interactions, (ii) cluster of orthologous groups (COG) of proteins, (iii) gene ontologies (GO), (iv) metabolic pathways (v) Swiss Prot keywords, (vi) InterPro domains - and (vii) generic functional categories. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible

Proper citation: FIVA - Functional Information Viewer and Analyzer (RRID:SCR_005776) Copy   

•   Source: SciCrunch Registry

http://www.betacell.org/

THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology.

Proper citation: Beta Cell Biology Consortium (RRID:SCR_005136) Copy   

•   Source: SciCrunch Registry

http://ccr.coriell.org/Sections/Collections/CDC/?SsId=16

A repository which houses DNA samples prepared from reference cell lines and are available for use in molecular genetic testing. The CF samples contain mutations associated with unique populations, combinations of IVS8 poly-thymidine tract variants, and mutations not previously available. Three DNA samples with homozygous MTHFR-related mutations are available. Hemochromatosis-associated samples include a compound HFE heterozygote and other combinations of HFE alleles. DNA samples with triplet repeats at the intermediate-range are available for HD and Fragile X syndrome. Mutations were confirmed in all cell lines from which the DNA has been prepared by reference testing and multi-laboratory pilot testing. Control DNA samples negative for all mutations are also available. Laboratories are encouraged to contact Coriell Cell Repositories to inquire about obtaining samples or donating samples as possible candidates for transformation.

Proper citation: CDC Cell and DNA Repository (RRID:SCR_004680) Copy   

•   Source: SciCrunch Registry

http://www.scrm.uzh.ch/biobank.html

The SCRM-CTBB offers state-of-the-art infrastructure and technologies (e.g. cryogenic work bench, semiautomatic cryogenic storage system, uninterrupted cooling chain) and is structured into two areas, including research and a GMP/GCP regulated therapeutic applications. Research: For pre-clinical studies, the SCRM-CTBB provides researchers guidance regarding cell and tissue cryo-preservation, comprising registration, handling, storage and distribution. In order to ensure complete traceability on samples and belonging information all processes are controlled by a Laboratory Information Management System (LIMS) and Quality Assurance (QA) system. The SCRM Biobank is designed to create database that allows connection with other biobanks nationally and internationally. This meta-data file will enable a unique scientific resource for interdisciplinary research. For every new study a contract is established describing the study and the disposition rights. Assistance in writing Biobank Agreements (BAs) and Material Transfer Agreements (MTAs) is provided. Therapeutical applications: As a new feature, apart from research, the SCRM Biobank enables the asservation and preservation of cells and tissues under GMP conditions for later therapeutic use. A special focus will be on a conceptional combination of private and public umbilical cord blood banking (hybrid banking), which allows autologous and/or allogeneic cell applications.

Proper citation: University of Zurich SCRM - Cell-and Tissue Biobank (RRID:SCR_004959) Copy   

•   Source: SciCrunch Registry