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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
AlzSWAN Knowledge Base
 
Resource Report
Resource Website
1+ mentions
AlzSWAN Knowledge Base (RRID:SCR_003017) AlzSWAN knowledgebase, portal, data or information resource, community building portal, knowledge environment THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A community-driven knowledgebase of Alzheimer disease, in which researchers can annotate scientific claims, data, and information, putting these into the context of testable hypotheses and treatment discovery. This SWAN project adds a collection of hand-curated hypotheses to a research paper, which are then related through a set of discourse relationships. They can be browsed and relations between claims, as well as support networks for a specific claim, are made and visualized. AlzSWAN is where you explore scientific knowledge about Alzheimer disease and share your own ideas, comments and questions in a semantically structured system. AlzSWAN is enabled by Semantic Web technology, a new standard for knowledge organization and transfer on the Web. AlzSWAN organizes and manages knowledge using formal knowledge descriptions called ontologies. Using these formal knowledge descriptions, they can tie statements made in scientific publications or on the Web to scientific evidence, biological terminologies, and knowledgebases, and to claims and counterclaims made by other researchers. hypothesis, claim, research paper, relationship, semantics, annotation is listed by: FORCE11
is related to: Semantic Web Applications in Neuromedicine (SWAN) Ontology
has parent organization: Alzheimer's Research Forum
Alzheimer's disease Ellison Medical Foundation ;
alz.org
PMID:17510163 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00524 SCR_003017 2026-08-15 11:22:23 1
GenePaint
 
Resource Report
Resource Website
100+ mentions
GenePaint (RRID:SCR_003015) GenePaint.org database, data or information resource, reference atlas, expression atlas, atlas Digital atlas of gene expression patterns in developing and adult mouse. Several reference atlases are also available through this site. Expression patterns are determined by non-radioactive in situ hybridization on serial tissue sections. Sections are available from several developmental ages: E10.5, E14.5 (whole embryos), E15.5, P7 and P56 (brains only). To retrieve expression patterns, search by gene name, site of expression, GenBank accession number or sequence homology. For viewing expression patterns, GenePaint.org features virtual microscope tool that enables zooming into images down to cellular resolution. gene expression, adult mouse, annotated, c57bl6, mouse, mouse embryo, mrna, non radioactive in situ hybridization, light microscopy, molecular neuroanatomy resource, in situ hybridization, embryonic, postnatal, adult, brain, head, annotation, rna probe, sequence, anatomical structure, FASEB list has parent organization: Max Planck Institute for Biophysical Chemistry; Gottingen; Germany
is parent organization of: GenePaint E15 Atlas
is parent organization of: GenePaint P7 Atlas
is parent organization of: GenePaint P56 Mouse Atlas
is parent organization of: GenePaint Interactive Anatomy Atlas
Burroughs Wellcome Fund ;
European Union ;
Max Planck Society ;
Merck Genome Research Institute ;
Romansky Endowment ;
NINDS ;
BMBF
PMID:14681479
PMID:22936000
nif-0000-00009, SCR_017526 SCR_003015 Atlas of Gene Expression Patterns in Mouse Embryo 2026-08-15 11:22:24 164
EUROpean Saccharomyces Cerevisiae ARchive for Functional Analysis
 
Resource Report
Resource Website
10+ mentions
EUROpean Saccharomyces Cerevisiae ARchive for Functional Analysis (RRID:SCR_003093) EUROSCARF biomaterial supply resource, material resource, organism supplier Archive of yeast strains and plasmids that were generated during various yeast functional analysis projects. plasmid, strain, wild type, deletion, tap fusion, degron, orf, functional analysis, yeast is listed by: One Mind Biospecimen Bank Listing
has parent organization: Goethe University Frankfurt am Main; Hessen; Germany
BMBF ;
European UnionROFAN I and II ;
European yeast industrial platform ;
federal state of Hessen
Free, Freely available nif-0000-30504 http://www.uni-frankfurt.de/fb15/mikro/EUROSCARF/indexhtml SCR_003093 2026-08-15 11:22:26 43
JETTA
 
Resource Report
Resource Website
1+ mentions
JETTA (RRID:SCR_003091) JETTA data processing software, software application, data analysis software, software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented July 6, 2017. Software to detect alternatively spliced exons between two conditions, for example, between two groups of treated and untreated patients in a typical clinical study. exon, exon splicing is listed by: OMICtools
has parent organization: Stanford University; Stanford; California
PMID:22433281 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01334 SCR_003091 2026-08-15 11:22:23 3
Effect Size Calculator
 
Resource Report
Resource Website
10+ mentions
Effect Size Calculator (RRID:SCR_003094) Effect Size Calculators production service resource, data analysis service, web application, software resource, service resource, analysis service resource Calculator for a variety of functions, including Cohen's d and the effect-size correlation, rYl, using means and standard deviations or independent groups t test values and df. calculator, cohen, cohen d, ryi, effect size correlation has parent organization: University of Colorado; Colorado Springs; USA Free, Freely available nif-0000-30507 https://lbecker.uccs.edu/ SCR_003094 2026-08-15 11:22:24 13
Biomedical Information Science and Technology Initiative
 
Resource Report
Resource Website
1+ mentions
Biomedical Information Science and Technology Initiative (RRID:SCR_003123) BISTI funding resource, portal, data or information resource, meeting resource, training resource, organization portal A consortium of representatives from each of the NIH institutes and centers. BISTI was established in May 2000 to serve as the focus of biomedical computing issues at the NIH. The mission of BISTI is to make optimal use of computer science and technology to address problems in biology and medicine by fostering new basic understandings, collaborations, and transdisciplinary initiatives between the computational and biomedical sciences. In support of this mission, the BISTI coordinates research grants, training opportunities, and scientific symposia associated with biomedical computing. Regular monthly meetings are conducted to discuss program status, future needs and directions, and topics of interest to the bioinformatics community. grant, funding opportunity, computer science, technology, biology, medicine, collaboration, transdisciplinary initiative, computation, biomedical sciences, bioinformatics, informatics has parent organization: National Institutes of Health NIH Blueprint for Neuroscience Research Free, Freely available nif-0000-00560 https://stip.oecd.org/stip/interactive-dashboards/policy-initiatives/2021%2Fdata%2FpolicyInitiatives%2F25417 SCR_003123 Biomedical Information Science Technology Initiative, BITSI - Biomedical Information Science and Technology Initiative, Biomedical Information Science & Technology Initiative 2026-08-15 11:22:26 1
BioCaster Ontology
 
Resource Report
Resource Website
BioCaster Ontology (RRID:SCR_003122) BCO ontology, data or information resource, controlled vocabulary A multilingual application ontology aimed at the early detection of public health events in the media. It aims to describe the terms and relations necessary to detect and risk assess public health events in the grey literature at an early stage; and bridge the gap between the (multilingual) grey literature and existing standards in biomedicine. The BCO focuses on the usage of terms and relations within informal unstructured reports which are often made at a pre-diagnostic stage of a disease outbreak by non-medically trained reporters. This is done to provide monitoring and early warning about public health hazards from online media reports. public health, text-mining, infectious disease, owl, skos, database has parent organization: Google Code
has parent organization: BioCaster
Infectious disease Free, Available for download, Freely available nlx_156797 http://born.nii.ac.jp/_dev/static/ontology SCR_003122 biocaster-ontology 2026-08-15 11:22:24 0
Genetic Analysis Package
 
Resource Report
Resource Website
1+ mentions
Genetic Analysis Package (RRID:SCR_003006) software resource GAP is designed as an integrated package for genetic data analysis of both population and family data. Currently, it contains functions for sample size calculations of both population-based and family-based designs, classic twin models, probability of familial disease aggregation, kinship calculation, some statistics in linkage analysis, and association analysis involving one or more genetic markers including haplotype analysis with or without environmental covariates. genetic, analysis, package, data, population, family, calculation, family, disease, aggregation, kinship, environmental, covariate, haplotype, marker nif-0000-30271 SCR_003006 GAP 2026-08-15 11:22:21 1
Primer3Plus
 
Resource Report
Resource Website
1000+ mentions
Primer3Plus (RRID:SCR_003081) Primer3Plus production service resource, data analysis service, software resource, source code, service resource, analysis service resource A web interface to the Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3. primer, dna sequence, primer design, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Primer3
has parent organization: Wageningen University and Research Centre; Gelderland; Netherlands
Howard Hughes Medical Institute ;
NHGRI R01-HG00257;
NHGRI P50-HG00098
PMID:17485472 Free, Freely available biotools:primer3plus, OMICS_02347 https://bio.tools/primer3plus SCR_003081 Primer3Plus - pick primers from a DNA sequence 2026-08-15 11:22:25 1860
NeuroML
 
Resource Report
Resource Website
10+ mentions
NeuroML (RRID:SCR_003083) NeuroML markup language, standard specification, interchange format, data or information resource, narrative resource A XML-based description language that provides a common data format for defining and exchanging descriptions of neuronal cell and network models. It facilitates the exchange of complex neural models, allows for greater transparency and accessibility of models, enhances interoperability between simulators and other tools, and supports the development of new software and databases. Exchange of network models will aid the investigation of structure-function relationships in neuroscience including theoretical studies relating connectivity patterns to normal and neurodegenerative network states. NeuroML is a free and open community effort developed with input from many contributors. They will need your help as the standards and tools continue to evolve. cell, network, neuron, model, computation tool, neuronal cell, network model is used by: Open Source Brain
is used by: CNrun
is related to: GENESIS Neural Database and Modelers Workspace
is related to: Neural Open Simulation
is related to: ChannelDB
is related to: neuroConstruct
has parent organization: University College London; London; United Kingdom
has parent organization: Arizona State University; Arizona; USA
is parent organization of: Tools in NeuroML
Free, Freely available nif-0000-00542 SCR_003083 Neuro-Markup Language 2026-08-15 11:22:24 34
Japanese Genotype-phenotype Archive (JGA)
 
Resource Report
Resource Website
10+ mentions
Japanese Genotype-phenotype Archive (JGA) (RRID:SCR_003118) JGA database, data repository, storage service resource, data or information resource, service resource A service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects. The JGA contains exclusive data collected from individuals whose consent agreements authorize data release only for specific research use or to bona fide researchers. Strict protocols govern how information is managed, stored and distributed by the JGA. Once processed, all data are encrypted. The JGA accepts only de-identified data approved by JST-NBDC. The JGA implements access-granting policy whereby the decisions of who will be granted access to the data resides with the JST-NBDC. After data submission the JGA team will process the data into databases and archive the original data files. The accepted data types include manufacturer-specific raw data formats from the array-based and new sequencing platforms. The processed data such as the genotype and structural variants or any summary level statistical analyses from the original study authors are stored in databases. The JGA also accepts and distributes any phenotype data associated with the samples. For other human biological data, please contact the NBDC human data ethical committee. biomedical, genetic, phenotype, gene, data sharing, genotype is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
has parent organization: DNA DataBank of Japan (DDBJ)
has parent organization: NBDC - National Bioscience Database Center
Free, Freely available nlx_156741, r3d100010818 https://doi.org/10.17616/R3861Q http://trace.ddbj.nig.ac.jp/jga/, http://trace.ddbj.nig.ac.jp/jga/index_e.html SCR_003118 JGA, Japanese Genotype-phenotype Archive (JGA), Japanese Genotype-phenotype Archive 2026-08-15 11:22:24 37
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-08-15 11:22:23 4
MicroArray and Gene Expression Markup Language
 
Resource Report
Resource Website
1+ mentions
MicroArray and Gene Expression Markup Language (RRID:SCR_003023) MAGE-ML markup language, standard specification, interchange format, data or information resource, narrative resource A language / data exchange format designed to describe and communicate information about microarray based experiments that is based on XML and can describe microarray designs, microarray manufacturing information, microarray experiment setup and execution information, gene expression data and data analysis results. MAGE-ML has been automatically derived from Microarray Gene Expression Object Model (MAGE-OM), which is developed and described using the Unified Modelling Language (UML) -- a standard language for describing object models. Descriptions using UML have an advantage over direct XML document type definitions (DTDs), in many respects. First they use graphical representation depicting the relationships between different entities in a way which is much easier to follow than DTDs. Second, the UML diagrams are primarily meant for humans, while DTDs are meant for computers. Therefore MAGE-OM should be considered as the primary model, and MAGE-ML will be explained by providing simplified fragments of MAGE-OM, rather then XML DTD or XML Schema. (from the description by Ugis Sarkans) The field of gene expression experiments has several distinct technologies that a standard must include. These include single vs. dual channel experiments, cDNA vs. oligonucleotides. Because of these different technologies and different types of gene expression experiments, it is not expected that all aspects of the standard will be used by all organizations. Given the massive amount of data associated with a single set of experiments, it is felt that Extensible Markup Language (XML) is the best way to describe the data. The use of a Document Type Definition (DTD) allows a well-defined tag set, a vocabulary, to describe the domain of gene expression experiments. It also has the virtue of compressing very well so that files in an XML format compress to ten percent of their original size. XML is now widely accepted as a data exchange format across multiple platforms. microarray, gene expression, bioinformatics is listed by: 3DVC
is related to: MADAM
is related to: MIAME
is related to: RNA Abundance Database
has parent organization: European Bioinformatics Institute
has parent organization: MAGE
European Union ;
TEMBLOR project
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30390 SCR_003023 MicroArray and Gene Expression Markup Language 2026-08-15 11:22:21 5
JAX Neuroscience Mutagenesis Facility Protocols
 
Resource Report
Resource Website
JAX Neuroscience Mutagenesis Facility Protocols (RRID:SCR_003021) NMF Protocols data or information resource, narrative resource, experimental protocol THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. The Neuroscience Mutagenesis Facility of the Jackson Laboratory (NMF) was established to produce new neurological mouse models that could serve as experimental models for the exploration of basic neurobiological mechanisms and diseases. The protocols are available. The impetus for the program resulted from the recognition that * the value of genomic data would remain limited unless more information about the functionality of its individual components became available, and * the task of linking genes to specific behavior would best be accomplished by employing a combination of different approaches. In an effort to complement already existing programs, the Neuroscience Mutagenesis Facility decided to use: a random, genome-wide approach to mutagenesis, i.e. N-ethyl-N-nitrosourea (ENU) as the mutagen; a three-generation back-cross breeding scheme to focus on the detection of recessive mutations; behavioral screens selective for the detection of phenotypes deemed useful for the program goals. Protocols: * Genetics ** Production of Mice for a Genome-Wide ENU Mutagenesis Screen ** Production of Mice using Chemical Mutagenesis of Mouse ES Cells * Protocols ** Step by step procedures-- Mouse mutagenesis with ENU ** Step by step procedures-- ES Cell mutagenesis with EMS * Phenotyping: Overview * Protocols:(currently only screens marked * are in use) ** Acoustic startle response (ASR) ** Auditory brainstem response (ABR) ** CLAMSTM(former CCMS) ** Creatine kinase ** Developmental Screen * ** Eye and Vision * ** Gait Analysis ** Gustation ** Observation * ** Seizure threshold * ** Additional Background Information mutant mouse strain, genetically-modified mouse, motor system function, impairment of function, eye disease, eye disorder, ophthalmological disorder, ophthalmic disorder, ocular disease, disease of eye, epilepsy, epileptic seizure, seizure disorder, gustatory system function, taste system function, bioinformatics, acoustic startle response, auditory brainstem response, creatine kinase, development, eye, vision, gait, gustation, observation, seizure, mutagenesis, n-ethyl-n-nitrosourea, es cell mutagenesis, ems, genetics, phenotyping has parent organization: JAX Neuroscience Mutagenesis Facility THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00527 SCR_003021 JAX Protocols, Protocols of the NMF, Protocols of the Neuroscience Mutagenesis Facility, JAX NMF Protocols 2026-08-15 11:22:23 0
R-pbh5
 
Resource Report
Resource Website
R-pbh5 (RRID:SCR_003026) software toolkit, software resource, software library Software library for accessing data in HDF5 files produced by Pacific Biosciences sequencing machines. The R package supports accessing data from: cmp.h5, bas.h5, pls.h5, and trc.h5. software package, r is listed by: OMICtools Free, Available for download, Freely available OMICS_05139 https://github.com/extemporaneousb/R-pbh5 SCR_003026 2026-08-15 11:22:23 0
Isopat
 
Resource Report
Resource Website
Isopat (RRID:SCR_003025) software resource Software function that calculates the isotopic pattern (fine structures) for a given chemical formula. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
Free, Available for download, Freely available OMICS_02409 https://isopat.sourceforge.net/ SCR_003025 isopat: Calculation of isotopic pattern for a given molecular formula 2026-08-15 11:22:24 0
BRAIN
 
Resource Report
Resource Website
10+ mentions
BRAIN (RRID:SCR_003018) software resource Software package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23350948 GNU General Public License, v2 biotools:brain, OMICS_02410 https://bio.tools/brain SCR_003018 Baffling Recursive Algorithm for Isotopic distributioN calculations, Baffling Recursive Algorithm for Isotope distributioN 2026-08-15 11:22:21 47
Developmental Therapeutics Program
 
Resource Report
Resource Website
500+ mentions
Developmental Therapeutics Program (RRID:SCR_003057) DTP topical portal, funding resource, portal, data or information resource, service resource Portal for preclinical information and research materials, including web-accessible data and tools, NCI-60 Tumor Cell Line Screen, compounds in vials and plates, tumor cells, animals, and bulk drugs for investigational new drug (IND)-directed studies. DTP has been involved in the discovery or development of more than 70 percent of the anticancer therapeutics on the market today, and will continue helping the academic and private sectors to overcome various therapeutic development barriers, particularly through supporting high-risk projects and therapeutic development for rare cancers. Initially DTP made its drug discovery and development services and the results from the human tumor cell line assay publicly accessible to researchers worldwide. At first, the site offered in vitro human cell line data for a few thousand compounds and in vitro anti-HIV screening data for roughly 42,000 compounds. Today, visitors can find: * Downloadable in vitro human tumor cell line data for some 43,500 compounds and 15,000 natural product extracts * Results for 60,000 compounds evaluated in the yeast assay * In vivo animal model results for 30,000 compounds * 2-D and 3-D chemical structures for more than 200,000 compounds * Molecular target data, including characterizations for at least 1,200 targets, plus data from multiple cDNA microarray projects In addition to browsing DTP's databases and downloading data, researchers can request individual samples or sets of compounds on 96-well plates for research, or they can submit their own compounds for consideration for screening via DTP's online submission form. Once a compound is submitted for screening, researchers can follow its progress and retrieve data using a secure web interface. The NCI has collected information on almost half a million chemical structures in the past 50 years. DTP has made this information accessible and useful for investigators through its 3-D database, a collection of three-dimensional structures for more than 200,000 drugs. Investigators use the 3-D database to screen compounds for anticancer therapeutic activity. Also available on DTP's website are 127,000 connection tables for anticancer agents. A connection table is a convenient way of depicting molecular structures without relying on drawn chemical structures. As unique lists of atoms and their connections, the connection tables can be indexed and stored in computer databases where they can be used for patent searches, toxicology studies, and precursor searching, for example., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. cell line, drug discovery, drug development, drug, treatment, therapy, biopharmaceutical, bortezomib, paclitaxel, romidepsin, eribulin, sipuleucel-t, anticancer therapeutic, compound, natural product extract, animal model, in vivo, in vitro, chemical structure, chemical, structure, anti-hiv, anticancer, molecular structure, database, chemotherapeutic agent, testing, drug synthesis, chemistry, grant, contract, information technology, molecular pharmacology, natural product, pharmaceutical, screening technology, toxicology, pharmacology, screening, FASEB list is used by: NIF Data Federation
is related to: Integrated Cell Lines
has parent organization: National Cancer Institute
Cancer, Tumor NCI THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30447 https://medschool.cuanschutz.edu/colorado-cancer-center/research/research-programs/developmental-therapeutics SCR_003057 Developmental Therapeutics Program NCI/NIH 2026-08-15 11:22:22 571
SASqPCR
 
Resource Report
Resource Website
1+ mentions
SASqPCR (RRID:SCR_003056) software resource All-in-one computer program for robust and rapid analysis of quantitative reverse transcription real-time polymerase chain reaction (RT-qPCR) data in SAS. It incorporates all functions important for RT-qPCR data analysis including assessment of PCR efficiencies, validation of internal reference genes and normalizers, normalization of confounding variations across samples and statistical comparisons of target gene expression in parallel samples. The program is highly automatic in data analyses and result output. The input data have no limitations for the number of genes or cDNA samples. Users can simply change the macro variables to test various analytical strategies, optimize results and customize the analytical processes. The program is also extendable allowing advanced SAS users to develop particular statistical tests appropriate for their experimental designs. Thus users are the actual decision-makers controlling RT-qPCR data analyses. The program has to be used in SAS software; however, extensive SAS programming knowledge is not required. standalone software, computation, analysis, statistics, rt-qpcr, cdna, mrna, gene expression, quantification, reference gene, normalization, sas is listed by: OMICtools
has parent organization: Google Code
PMID:22238653 Free, Available for download, Freely available OMICS_02375 SCR_003056 SASqPCR: robust and rapid analysis of RT-qPCR data in SAS 2026-08-15 11:22:23 6
SurvComp
 
Resource Report
Resource Website
50+ mentions
SurvComp (RRID:SCR_003054) survcomp software resource R package providing functions to assess and to compare the performance of risk prediction (survival) models. differential expression, gene expression, visualization, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: Bioconductor
PMID:21903630 Free, Available for download, Freely available OMICS_02373 SCR_003054 survcomp - Performance Assessment and Comparison for Survival Analysis 2026-08-15 11:22:22 61

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