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https://www.ohio.edu/research/sharedequipment/ohio-university-genomics-facility
Facility offers Next-Generation Sequencing services, Sanger sequencing, Fragment Analysis, qPCR, data analysis. Provided services include DNA sequencing, fragment analysis, RNA, DNA, protein and cell cytometry through various equipment.
Proper citation: Ohio University Genomics Core Facility (RRID:SCR_012487) Copy
http://www.scienceexchange.com/facilities/nanoracks-u-s-national-lab
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 10th,2023. NanoRacks provides microgravity research facilities and currently includes NanoLab Platforms, NanoRacks Plate Reader, NanoRacks Microscope and NanoRacks MixStix.
Proper citation: NanoRacks (RRID:SCR_012608) Copy
http://www.scienceexchange.com/facilities/centre-for-translational-and-applied-genomics-ctag
PHSA Laboratories'''' Centre for Translational and Applied Genomics (CTAG) is a a CAP Accredited genomics and molecular pathology core facility supported by a world class team of molecular pathologists with diverse clinical and research interests and technical skills. CTAG operates at PHSA agencies including the BC Cancer Agency, BC Centre for Disease Control, BC Children''''s Hospital and BC Women''''s Hospital & Health Centre. CTAG offers a broad range of analytical services to the public and private sectors. As a division of PHSA Laboratories, CTAG''''s mission is to develop novel laboratory tests to improve the management of a diverse spectrum of disorders including cancer, infectious diseases, and inherited syndromes.
Proper citation: PHSA Centre for Translational and Applied Genomics (RRID:SCR_012446) Copy
http://www.ohri.ca/stemcore/Default.aspx
StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.
Proper citation: Ottawa Hospital Research Institute StemCore Laboratories Core Facility (RRID:SCR_012601) Copy
http://www.scienceexchange.com/facilities/high-resolution-plant-phenomics-centre-hrppc-csiro
The High Resolution Plant Phenomics Centre (HRPPC) is the Canberra node of the Australian Plant Phenomics Facility and is located in Canberra at CSIRO Plant Industry and the Australian National University. This centre focuses on _������_deep phenotyping_���� (delving into metabolism and physiological processes within the plant) and _������_reverse phenomics_���� (dissecting traits to discover their mechanistic basis). Next generation research tools are applied to probe plant function and performance, under controlled conditions and in the field. Recent advances in robotics, imaging and computing are used in applying these technologies and scaling them from the single plant to the ecosystem level. Two levels of service are provided in the HRPPC. First, projects can be housed in the _������_Research Hotel_���� environment where screening systems can be developed using facility staff and resources then deployed in the facility and in the user''''s home institution. Second, users_������_ material can be screened for specific attributes using one or more of the modules housed at CSIRO or the ANU. The HRPPC''''s focus is on flexibility from cereals to dicots and woody perennials at all stages of development.
Proper citation: CSIRO High Resolution Plant Phenomics Centre (RRID:SCR_012570) Copy
http://www.scienceexchange.com/facilities/penn-microarray-core-facility-upenn
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. Penn Microarray Facility provides instrumentation and expertise for RNA transcript profiling. DNA microarrays provide a highly parallel means of measuring the abundance of RNA for targeted genes in a biological sample. The Facility supports two microarray formats: oligonucleotide arrays synthesized by Affymetrix Inc. and arrays of probes printed in-house on glass slides. This reflects our goal of offering a range of cost and performance options suitable for a variety of experimental questions.
Proper citation: Penn Microarray Core Facility (RRID:SCR_012610) Copy
http://www.scienceexchange.com/facilities/athymic-animal-and-xenograft-core-facility-cwru
The Athymic Animal and Xenograft Core Facility provides facilities for breeding and housing of athymic nude mice (NCRnu/nu) and rats, and other immunodeficient mice. The core provides pathogen-free facilities for experimentation using immunodeficient animal hosts and normal human cells and human tumor cell xenografts. Core staff maintain and monitor animals housed in the facility, and provide users with a variety of services, including transportation, health reports, animal handling, and experimental procedures. The staff will also train users in animal handling and experimental procedures. Entry to the animal facilities is controlled by key card access and is limited to employees who are listed on an IACUC-approved protocol, have enrolled in an animal contact Occupational Health program, and have completed access training. Experimental procedures, listed below, are provided either at the Case facility or in the Animal Tumor Core (ATC) at the Cleveland Clinic Taussig Cancer Institute. The Taussig Cancer Institute ATC was established in 2002 to help principal investigators at the Cleveland Clinic and CWRU perform tumor experiments, angiogenesis studies, and pharmacokinetic studies in mice. The ATC conducts syngeneic murine tumor experiments, and human xenograft (athymic nude mouse) tumor experiments. In addition, the ATC has developed several orthotopic human carcinoma models: HT-29 colon, HCT-116 colon, SW480 colon (all metastasize to liver), ACHN renal, A549 lung, multiple prostate, bladder, melanoma and ovarian tumors. ATC services utilize murine models to facilitate in vivo cancer drug screening, drug evaluation, and drug development. The core''''s goal is to help in evaluation of new pharmacologic agents by providing data on tumor growth, metastasis, angiogenesis, and gene expression. The facility also provides consultation services to assist the investigator in all aspects of animal tumor model development.
Proper citation: CWRU Athymic Animal and Xenograft Core Facility (RRID:SCR_012459) Copy
https://www.ualberta.ca/chemistry/facilities-and-resources/mass-spectrometry-facility.html
There are currently eleven mass spectrometers housed in the mass spectrometry laboratory covering most ionisation techniques from electron impact to MALDI. 8 or more samples submitted at the same time and run under identical conditions qualify for a 25% discount for GC-coupled, LC-coupled and in-gel digest LC/MS/MS experiments Variable rate for high molecular weight samples (i.e., more than 3000 u), depending on the instrument and operator time required for the analysis. There will be a 50% surcharge for all RUSH orders (queue jumping).
Proper citation: UAlberta Mass Spectrometry Facility - Department of Chemistry (RRID:SCR_012613) Copy
http://www.scienceexchange.com/facilities/nucleic-acids-core-facility
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Nucleic Acids Core Facility offers automated DNA sequencing with data analysis, custom DNA synthesis, genome project services, gene amplification services, and robotic application custom projects. These services are provided to researchers at the HSC and others in the surrounding scientific community. Our mission is to offer high quality synthesis and sequencing services to researchers through cutting edge instrumentation and a service-oriented and knowledgeable staff.
Proper citation: UTHSCSA Nucleic Acids Core Facility (RRID:SCR_012614) Copy
http://www.scienceexchange.com/facilities/ontario-cancer-biomarker-network
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 14,2024. OCBN is a not-for-profit corporation that was established in 2005 with a grant from the Ontario Institute for Cancer Research and the Ontario Ministry of Research and Innovation for the purpose of advancing biomarker research. The OCBN is designed to enable the co-ordination and amplification of the proteomic and genomic biomarker research efforts throughout the province of Ontario to better service academia and industry, whether provincially, nationally or internationally. As such, OCBN is much more than simply an academic research consortium. Residing at the core of the network is the OCBN Central Facility, located at the MaRS Incubator www.marsdd.com in the heart of the biomedical research community in Toronto, one of the most vibrant research hubs in the world. The Central Facility functions as the nexus for the network and its academic and industry partners by providing numerous support services for their clinical and basic research scientists in the conduct of their research.
Proper citation: Ontario Cancer Biomarker Network (RRID:SCR_012616) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 24,2024. IBBR DNA Sequencing Facility currently offers its customers NextGen sequencing.
Proper citation: UMD Sequencing Core - Institute of Bioscience and Biotechnology Research (RRID:SCR_012428) Copy
Core provides molecular biotechnology services and current molecular genetic methods. Services include DNA and RNA Extraction, transgenic mouse genotyping, Human Cell line Authentication, Sanger DNA Sequencing, Next-Generation sequencing platforms, Microsatellite DNA Typing, Agena multiplex SNP Genotyping, Real-time PCR, NanoString Gene Expression Analysis. Specializes in custom workflows that couple services with specific research needs.
Proper citation: Arizona Genetics Core (RRID:SCR_012429) Copy
http://www.neurodiscovery.harvard.edu/research/neurobehavior_laboratory.html
Core facility that provides the following services: Surgery/necropsy service. Mouse models have become a popular and successful approach to elucidating the physiological and pathological roles of individual genes and are truly crucial to accelerate the development of effective treatments and cures for Alzheimer''''s, Parkinson''''s, ALS, MS and other neurodegenerative diseases. The increasing demand for mouse behavioral studies within the neuroscience community has led the Harvard NeuroDiscovery Center to develop a major new, state of the art mouse behavior laboratory, located in the Longwood medical area and carefully designed to meet the exacting standards required for this type of work. The NeuroBehavior Laboratory (NBL) will provide the Harvard community and other investigators access to a broad range of reliable behavioral/cognitive tests necessary to analyze and interpret the impact of a genetic, surgical or pharmacologic manipulation on specific behaviors. They can provide: * Assistance with experimental design. * Support for grant applications that have a significant component of mouse neurobehavioral research. * Full, fee-for-service, mouse behavioral testing services. * Training in all aspects of mouse neurobehavioral testing. * Assistance with data analysis and interpretation.
Proper citation: HNDC NeuroBehavior Laboratory Core (RRID:SCR_012396) Copy
http://www.scienceexchange.com/facilities/center-for-structural-biology
The CSB provides an integrated platform of expertise, infrastructure and education to foster a wider use of structural biology by the UNC community. The CSB mission is to make structural biology available as a general tool to any researcher. Structures of macromolecules at atomic resolution have helped to revolutionize modern biology. Structural insight is often crucial for understanding the functions of biological macromolecules, including their interactions with small ligands (such as substrates, inhibitors, drugs) and other macromolecules (nucleic acids and/or proteins). Consequently, structural biology represents one of the pillars of basic biomedical research; it is indispensable for deciphering the details of life processes and for understanding the differences between natural and diseased states. Building on such insights, structural biology can assist in devising novel therapies, e.g., through structure-based or structure-aided drug design. The enormous information content available in high-resolution, three-dimensional structures has sparked the desire of non-structural biologists to examine the structures of the macromolecules that they study. Structural biology is technically demanding, and it requires highly specialized expertise. The CSB removes or reduces these barriers that usually prevent general researchers from engaging in structural biology-based projects by themselves.
Proper citation: UNC School of Medicine Center for Structural Biology (RRID:SCR_012430) Copy
https://unclineberger.org/tissueculture/
Supply center and provides UNC Lineberger members and UNC colleagues with tissue culture products including stocks media, media supplements, serum, salt solutions, antibiotics, cell culture flasks and dishes, and many other in vitro cell culture and molecular biology-related items, kits and cell lines. Cell lines include normal and transformed mammalian, avian, insect, amphibian/reptile, and hybridoma cells. Services include checking Fetal Bovine Serum for quality and efficacy. TCF partners with Genetica Cell Line Services to offer qPCR-based Mycoplasma contamination testing for cell or DNA samples. Utilizes Genetica Cell Line Services for STR profiling of cell lines.
Proper citation: University of North Carolina Lineberger Comprehensive Cancer Center Tissue Culture Core Facility (RRID:SCR_012432) Copy
http://www.scienceexchange.com/facilities/genomics-core--3
An Core facility
Proper citation: UT Arlington Genomics Core (RRID:SCR_012436) Copy
http://www.scienceexchange.com/facilities/bone-histomorphometry-lab
Evaluations at the tissue level are critical to musculoskeletal research. The Bone Histomorphometry Lab in the Department of Orthopedics has a rich history of conducting such in situ evaluations in both human and animal tissue. The primary expertise of the Bone Histo Lab is the processing of skeletal tissue in its calcified state for the preparation of histology slides.
Proper citation: Mayo Clinic Bone Histomorphometry Lab (RRID:SCR_012439) Copy
http://www.scienceexchange.com/facilities/embryonic-stem-cell-core
The Murine Embryonic Stem Cell Core has been created to help you create mutations in murine embryonic stem cells. The core has several missions including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation. The core utilizes quality-controlled cells developed here at Washington University.
Proper citation: WUSTL School of Medicine Embryonic Stem Cell Core (RRID:SCR_012441) Copy
http://www.scienceexchange.com/facilities/brains-on-line
Our mission at Brains On-Line is to provide preclinical research services to facilitate the development of new drugs that target the central nervous system. Brains On-Line benefits from its intimate connections with academia, as well as with several associated contract research organizations (CRO). Using our expertise, we aim to give full insight in the possibilities of your compound.
Proper citation: Brains On-Line (RRID:SCR_012565) Copy
http://www.scienceexchange.com/facilities/histopathology-and-tissue-shared-resource-georgetown
The HTSR offers a full complement of histology services through our combined Human Tissue Bank, histology, and IHC departments. The Human Tissue Bank supports tissue procurement and the retrieval of fresh frozen and archival paraffin blocks. The Histology laboratory provides processing, embedding and microtomy services both for fresh frozen and fixed tissues. The Histology lab also provides numerous routine and non-routine histological stains. The Immunohistochemistry (IHC) laboratory supports colorimetric and fluorescent IHC staining for established antibodies as well as the development of protocols for new antibodies. The IHC lab also supports TUNEL labeling and novel labeling techniques.
Proper citation: Georgetown Histopathology and Tissue Shared Resource (RRID:SCR_012489) Copy
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