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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Human Gut Microbiome Initiative Resource Report Resource Website |
Human Gut Microbiome Initiative (RRID:SCR_008137) | data or information resource, database, portal, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2022. Human Gut Microbiome Initiative (HGMI) seeks to provide simply annotated, deep draft genome sequences for 100 cultured representatives of the phylogenetic diversity documented by 16S rRNA surveys of the human gut microbiota. Humans are supra-organisms, composed of 10 times more microbial cells than human cells. Therefore, it seems appropriate to consider ourselves as a composite of many species - human, bacterial, and archaeal - and our genome as an amalgamation of human genes and the genes in ''our'' microbial genomes (''microbiome''). In the same sense, our metabolome can be considered to be a synthesis of co-evolved human and microbial traits. The total number of genes present in the human microbiome likely exceeds the number of our H. sapiens genes by orders of magnitude. Thus, without an understanding of our microbiota and microbiome, it not possible to obtain a complete picture of our genetic diversity and of our normal physiology. Our intestine is home to our largest collections of microbes: bacterial densities in the colon (up to 1 trillion cells/ml of luminal contents) are the highest recorded for any known ecosystem. The vast majority of phylogenetic types in the distal gut microbiota belong to just two divisions (phyla) of the domain Bacteria - the Bacteroidetes and the Firmicutes. Members of eight other divisions have also been identified using culture-independent 16S rRNA gene-based surveys. Metagenomic studies of complex microbial communities residing in our various body habitats are limited by the availability of suitable reference genomes for confident assignment of short sequence reads generated by highly parallel DNA sequencers, and by knowledge of the professions (niches) of community members. Therefore, HGMI, which represents a collaboration between Washington University''s Genome Center and its Center for Genome Sciences, seeks to provide simply annotated, deep draft genome sequences for 100 cultured representatives of the phylogenetic diversity documented by 16S rRNA surveys of the human gut microbiota. | ecosystem, firmicutes, bacterial, bacteroidetes, body, cell, diversity, genome, gut, habitat, human, metabolom, microbial, microbiome, microbiota, phylogenetic, rrna, sequence, specie, synthesis | has parent organization: Washington University in St. Louis; Missouri; USA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-20960 | http://genome.wustl.edu/projects/athaliana/ | SCR_008137 | HGMI | 2026-08-21 12:38:35 | 0 | |||||||
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dbEST Resource Report Resource Website 100+ mentions |
dbEST (RRID:SCR_008132) | data or information resource, data repository, database, service resource, storage service resource | Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms. | data, sequence, single, pass, cDNA, express, tag, bio.tools, gold standard |
is listed by: Debian is listed by: bio.tools has parent organization: NCBI |
PMID:8401577 | biotools:dbest, nif-0000-20937, r3d100010648 | http://www.ncbi.nlm.nih.gov/dbEST/, https://bio.tools/dbest, https://doi.org/10.17616/R3FG8P | SCR_008132 | database Expressed Sequence Tag (EST), database Expressed Sequence Tag | 2026-08-21 12:38:29 | 186 | |||||||
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Laboratory of Molecular Neuroscience, University of Oslo Resource Report Resource Website 1+ mentions |
Laboratory of Molecular Neuroscience, University of Oslo (RRID:SCR_008097) | UiO LMN | data or information resource, portal, topical portal | A laboratory that investigates the molecular mechanisms involved in the development of acute and chronic neurodegenerative disease, with a focus on the role of glutamate excitotoxicity. It aims at unraveling the molecular basis for cell death and edema development in stroke, and explores the pathophysiology of Alzheimer's disease and temporal lobe epilepsy. The main objective of the LMN is to advance understanding of the role of glutamate, as a transmitter substance in the normal brain and as a mediator of excitotoxicity in pathological conditions such as stroke. To this end the LMN employs several vital and nonvital imaging techniques. Model systems includes organotypic slice cultures and transgenic animals. An important focus of the LMN is to explore the role of DNA damage and repair in the pathogenesis of neurodegenerative disease. LMN is also engaged in research on molecular mechanism underlying brain edema, epilepsy, and Alzheimer's disease. | epilepsy, excitotoxicity, acute, alzheimer's disease, brain, brain edema, cell death, chronic, damage, dna, glutamate, imaging, model systems, molecular, molecular mechanism, neurodegenerative disease, neuroprotective, neuroscience, repair, stroke, transmitter | has parent organization: University of Oslo; Oslo; Norway | nif-0000-11675 | SCR_008097 | University of Oslo LMN | 2026-08-21 12:38:28 | 2 | ||||||||
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Tulane National Biomedical Research Center Resource Report Resource Website 500+ mentions |
Tulane National Biomedical Research Center (RRID:SCR_008167) | TNPRC | data or information resource, disease-related portal, organization portal, portal, topical portal | Center focused on understanding human health problems, including infectious diseases that require the use of nonhuman primates to develop diagnostics, therapeutics and preventive strategies. Primary research interests include developing vaccines, treatments and diagnostic tools for infectious diseases such as AIDS, tuberculosis, CMV, COVID-19, Lyme disease, and malaria. TNPRC has both biosafety level 2 and biosafety level 3 laboratories facilities to accommodate various research needs, and is the only National Primate Research Center with Regional Biosafety Laboratory. | NPRC, NPRC Consortium, ORIP, primate research, |
is listed by: National Primate Research Center Consortium has parent organization: Tulane University; Louisiana; USA |
NIH Office of the Director P51 OD011104; NIH Office of the Director U42 OD010568; NIH Office of the Director U42 OD024282 |
nif-0000-24360 | https://orip.nih.gov/comparative-medicine/programs/vertebrate-models | SCR_008167 | Tulane National Primate Research Center | 2026-08-21 12:38:36 | 866 | ||||||
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Interaction Proteome Project Resource Report Resource Website 1+ mentions |
Interaction Proteome Project (RRID:SCR_008043) | IPP | data or information resource, portal, simulation software, software application, software resource, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 28, 2013. (URL is no longer valid) A platform for high-throughput proteomic analysis. Major objectives of IPP include the establishment of a broadly applicable platform of routine methods for the analysis of protein interaction networks in bio-medical research. A multidisciplinary approach will address; * their validation by cell biological, biochemical and biophysical methods. * their collection in a new type of public database. * their exploitation and use for in silico simulations of protein-interaction networks. The innovations generated in IPP will provide the basis for an efficient analysis and systems modeling of fundamental biological processes in health and disease. It will develop novel technology, including a high-end mass spectrometer with extremely large dynamic range, high-density peptide arrays, and improved visualization technology for light and electron microscopy. Additionally, the novel technologies will be validated with selected model systems of high relevance to medicine and biotechnology. Extensive bioinformatics support is a key element in the project to cope with the massive increase in experimental data on protein interactions obtained using the novel technologies. In particular, the efficient integration of disparate data sets represents a key challenge in proteomics and functional genomics. Therefore, the consortium includes the creator of the only European protein-interactions database, MINT. The multi-disciplinary efforts required in the scientific program of IPP are organized into four sub-projects (SP): * SP1: Tools for interaction analysis - SP1 is dedicated to the development of innovative proteomics technology to map protein-interaction networks and their cellular topology for the interaction analyses in SP2 and SP3. * SP2: Identification of interaction partners for protein domains - SP2 will generate (high throughput) data for important protein-protein interactions defined by bioinformatics and biomedical interest and by SP3, utilizing technology developed in SP1. * SP3: Functional analysis of interactions - SP3 focuses on the validation of technologies and tools developed in SP1. It will perform functional analyses of protein-interactions in medically and biochemically relevant prokaryotic and eukaryotic (mammalian) model systems. * SP4: Interactome database and modelling - SP4 provides the required bioinformatics infrastructure for the project, comprising the improvement of the public MINT database for the collection and dissemination of the interactome data; modelling and simulation of protein-interaction networks characterised in SP2 and SP3; and the dissemination of the technology developments to the scientific community. | electron, eukaryotic, biochemical, bioinformatics, biological, biomedical, biophysical, biotechnology, cell, development, disease, domain, genomics, health, interaction, light, mammalian, map, mass spectrometer, medicine, microscopy, model, modeling, network, peptide array, prokayotic, protein interaction, proteome, proteomics, silico, simulation, system, technology, tool, protein interaction | has parent organization: Max Planck Institute of Biochemistry; Martinsried; Germany | European Union | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-10259 | SCR_008043 | Interaction Proteome | 2026-08-21 12:38:33 | 1 | ||||||
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Atlas of Medical Parasitology Resource Report Resource Website |
Atlas of Medical Parasitology (RRID:SCR_008163) | A.M.P., AMP | data or information resource, data repository, database, image repository, service resource, storage service resource |
Database of images on medical parasitology created to provide educational materials for medical students primarily, but professional workers in medical or paramedical fields may also refer to this site covering the significant parasites in the world. Each database of protozoans, nematodes, trematodes, cestodes and arthropods contains information on the morphology, life cycle, geographical distribution, symptoms, prevention, etc. Users who wish to contribute can send the editor unpublished images of human parasites (microscopical, clinical, radiological or epidemiological aspects of human parasitic infections) by mail or e-mail. Pathology specimens (slide, samples) are welcome too. The A.M.P. received the citation of reliable sources such as Parasitology today and The Lancet, and is now listed in the Internet Resources on Specific Infectious Diseases Topics of the Mandell, Douglas and Bennets Principles and Practice of Infectious Diseases Fifth Edition. This website was established with a great contribution of the PROJECT COLLABORATORS and many contributors of The Korean Society for Parasitology. |
epidemiological, clinical, disease, human, infection, medical, microscopical, parasite, parasitic, parasitology, pathology, radiological, specimen, morphology, life cycle, geographical distribution, symptom, prevention, human parasite, biospecimen repository, training material, image | has parent organization: Chungbuk National University; Cheongju; South Korea | Human parasitic infection | Ministry of Health and Welfare - Republic of Korea ; Korean Medical Research Information Center |
The community can contribute to this resource | nif-0000-21025 | http://www.cdfound.to.it/_atlas.htm | SCR_008163 | Web Atlas of Medical Parasitology | 2026-08-21 12:38:35 | 0 | ||||
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All the Virology on the WWW Resource Report Resource Website |
All the Virology on the WWW (RRID:SCR_008159) | data or information resource, portal, topical portal | All the Virology on the WWW is a site for virology information on the Internet. They have collected all the virology related web sites that might be of interest to virologists, and others interested in learning more about viruses. Additionally, they have created an index to virus pictures on the web, The Big Picture Book of Viruses, which also functions as a resource for viral taxonomy. A collection of some of the best Online Virology and Microbiology Course Notes available can also be found here. If users are interested in even more information, The Virology Bookshop, an on-line microbiology and virology bookstore with a significant discount for our users. It is their goal that this site will provide both the professional virologist and the general public with access to information about viruses. Over the past several years, these pages have grown to encompass something of interest for everyone. The lists of virology related sites are divided into multiple pages, all of which are accessible from this page and from the more descriptive Complete Table of Contents. There are also links to Virology Dictionaries if users are confused by some of this site''s more technical content. These sites are listed without bias and with much organization Categories: Metadatabases and Directories | database, definition, microbiology, picture, taxonomy, viral, virology, virus, job, image, journal | nif-0000-21017 | SCR_008159 | All the Virology on the WWW | 2026-08-21 12:38:35 | 0 | ||||||||||
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GeneNetWorks Resource Report Resource Website 1+ mentions |
GeneNetWorks (RRID:SCR_008034) | data acquisition software, data analysis software, data or information resource, data processing software, data visualization software, database, software application, software resource | GeneNetWorks is designed for accumulation of experimental data, data navigation, data analysis, and analysis of dependencies in the field of gene expression regulation. It integrates the databases and programs for processing the data about structure and function of DNA, RNA, and proteins, together with the other information resources important for gene expression description. The unique property of above described system is that all the resources within the system GeneNetWorks are divided according to the natural hierarchy of molecular genetic systems and has the following levels: (1) DNA; (2) RNA; (3) proteins; and (4) gene networks. Each module contains: 1) experimental data represented as a database or some sample; 2) program for data analysis; 3) results of an automated data processing; 4) tools for the graphical representation of these data and the results of the data analyses. | experimental, expression, gene, gene regulation, genetic, analysis, data, dna, graphical, molecular, navigation, network, program, protein, rna, software, system | nif-0000-10232 | SCR_008034 | GNW | 2026-08-21 12:38:26 | 1 | ||||||||||
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Gene Regulation Databases Resource Report Resource Website 100+ mentions |
Gene Regulation Databases (RRID:SCR_008033) | Gene Regulation Public Databases | data or information resource, portal, topical portal | In an effort to strongly support the collaborative nature of scientific research, BIOBASE offers academic and non-profit organizations free access to reduced functionality versions of their products. TRANSFAC Professional provides gene regulation analysis solutions, offering the most comprehensive collection of eukaryotic gene regulation data. The professional paid subscription gives customers access to up-to-date data and tools not available in the free version. The public databases currently available for academic and non-profit organizations are: * TRANSFAC: contains data on transcription factors, their experimentally-proven binding sites, and regulated genes. Its broad compilation of binding sites allows the derivation of positional weight matrices. * TRANSPATH: provides data about molecules participating in signal transduction pathways and the reactions they are involved in, resulting in a complex network of interconnected signaling components.TRANSPATH focuses on signaling cascades that change the activities of transcription factors and thus alter the gene expression profile of a given cell. * PathoDB: is a database on pathologically relevant mutated forms of transcription factors and their binding sites. It comprises numerous cases of defective transcription factors or mutated transcription factor binding sites, which are known to cause pathological defects. * S/MARt DB: presents data on scaffold or matrix attached regions (S/MARs) of eukaryotic genomes, as well as about the proteins that bind to them. S/MARs organize the chromatin in the form of functionally independent loop domains gained increasing support. Scaffold or Matrix Attached Regions (S/MARs) are genomic DNA sequences through which the chromatin is tightly attached to the proteinaceous scaffold of the nucleus. * TRANSCompel: is a database on composite regulatory elements affecting gene transcription in eukaryotes. Composite regulatory elements consist of two closely situated binding sites for distinct transcription factors, and provide cross-coupling of different signaling pathways. * PathoSign Public: is a database which collects information about defective cell signaling molecules causing human diseases. While constituting a useful data repository in itself, PathoSign is also aimed at being a foundational part of a platform for modeling human disease processes. | element, eukaryote, eukaryotic, expression, functionally, gene, genome, alignment, bind, binding site, cell, chromatin, collaborative, component, coupling, disease, dna, domain, human, matrix, molecular weight, molecule, mononucleotide, network, nucleotide, nucleus, pathological, protein, region, regulated, regulatory, scientific research, sequence, signaling, signal pathway, transcription factor, molecular neuroanatomy resource |
lists: TRANSFAC has parent organization: BIOBASE Corporation |
BIOBASE | nif-0000-10230 | SCR_008033 | gene-regulation.com: Public Databases for Academic and Non-profit Organizations | 2026-08-21 12:38:33 | 130 | |||||||
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HPV Sequence Database Resource Report Resource Website 1+ mentions |
HPV Sequence Database (RRID:SCR_008154) | data or information resource, database, portal, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented August 23, 2016. The Human Papillomaviruses Database collects, curates, analyzes, and publishes genetic sequences of papillomaviruses and related cellular proteins. It includes molecular biologists, sequence analysts, computer technicians, post-docs and graduate research assistants. This Web site has two main branches. The first contains our four annual data books of papillomavirus information, called Human Papillomaviruses: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences. and the second contains papillomavirus genetic sequence data. There is also a New Items location where we store the latest changes to the database or any other current news of interest. Besides the compendium, we also provide genetic sequence information for papilloma viruses and related cellular proteins. Each year they publish a compendium of papillomavirus information called Human Papillomaviruses: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences. which can now be downloaded from this Web site. | gene, genetic, alignment, amino acid, biologist, cellular protein, genome, human, molecular, papilloma, papillomavirus, phylogenetic, sequence, virus | has parent organization: Los Alamos National Laboratory | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-21000 | http://www.stdgen.lanl.gov/ | SCR_008154 | HPVSD | 2026-08-21 12:38:30 | 4 | |||||||
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Genomatix Software: Understanding Gene Regulation Resource Report Resource Website 500+ mentions |
Genomatix Software: Understanding Gene Regulation (RRID:SCR_008036) | data analysis software, data or information resource, data processing software, database, narrative resource, portal, short course material, software application, software resource, topical portal, training material | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 13,2026. Genomatix is a privately held company that offers software, databases, and services aimed at understanding gene regulation at the molecular level representing a central part of systems biology. Its multilayer integrative approach is a working implementation of systems biology principles. Genomatix combines sequence analysis, functional promoter analysis, proprietary genome annotation, promoter sequence databases, comparative genomics, scientific literature data mining, pathway databases, biological network databases, pathway analysis, network analysis, and expression profiling into working solutions and pipelines. It also enables better understanding of biological mechanisms under different conditions and stimuli in the biological context of your data. Some of Genomatix'' most valuable assets are the strong scientific background and the years of experience in research & discovery as well as in development & application of scientific software. Their firsthand knowledge of all the complexities involved in the in-silico analysis of biological data makes them a first-rate partner for all scientific projects involving the evaluation of gene regulatory mechanisms. The Genomatix team has more than a decade of scientific expertise in the successful application of computer aided analysis of gene regulatory networks, which is reflected by more than 150 peer reviewed scientific publications from Genomatix'' scientists More than 35,000 researchers in industry and academia around the world use this technology. The software available in Genomatix are: - GenomatixSuite: GenomatixSuite is our comprehensive software bundle including ElDorado, Gene2Promoter, GEMS Launcher, MatInspector and MatBase. GenomatixSuite PE also includes BiblioSphere Pathway Edition. Chromatin IP Software - RegionMiner: Fast, extensive analysis of genomic regions. - ChipInspector: Discover the real power of your microarray data. Genome Annotation Software - ElDorado: Extended Genome Annotation. - Gene2Promoter: Retrieve & analyze promoters - GPD: The Genomatix Promoter Database, which is now included with Gene2Promoter. Knowledge Mining Software - BiblioSpere : The next level of pathway/genomics analysis. - LitInspector: Literature and pathway analysis for free. Sequence Analysis Software - GEMS Launcher: Our integrated collection of sequence analysis tools. - MalInspector: Search transcription factor binding sites - MatBase: The transcription factor knowledge base. Other (no registration required) Software - DiAlign: Multiple alignment of DNA/protein sequence. - Genomatix tools: Various small tools for sequence statistics, extraction, formatting, etc. | effect, expression, functional, gene, genome, alignment, analysis, annotation, biological, cascade, cell, data, dna, in-silico analysis, mechanism, metabolic pathway, microarray, mining, molecular, network, pathway, promoter, protein, region, regulation, scientific, sequence, signaling, software, stimulus, systems biology, technology, text mining, transcription, FASEB list | has parent organization: Genomatix Solutions | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-10236 | http://www.genomatix.de/products/index.html | SCR_008036 | Genomatix | 2026-08-21 12:38:33 | 887 | |||||||
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U.S. Pig Genome Project Resource Report Resource Website |
U.S. Pig Genome Project (RRID:SCR_008151) | data or information resource, database, portal, topical portal | Database and resources on the pig genome. | embryo, embryonic, environmental, exercise, exposure, fat, feed, feeding, fibroblast, food, foot and mouth disease, function, genetic, acute, additive, alcohol, alcoholism, atherosclerosis, bed, behavior, biological, bone, breed, cancer, cell, chronic, clone, degenerative, density, deposition, dermal, developmental, diabetes, dietary, digestive, disease, genome, genomic, growth, habit, healing, human, hypertension, kidney, mammal, map, melanoma, metabolism, nephropathy, nuclear, nutrition, obesity, omnivore, organ, organism, parenteral, pathogen, pattern, phenotype, phenotypic, physiology, pig, pollutant, population, porcine, prenatal, pulmonary, reproductive, respiratory, retinal, sex, shock, size, social, somatic, structure, swine, taxon, technique, tissue, tobacco, transplantation, variation, vascular, warfare, xenobiotic, model | is listed by: 3DVC | nif-0000-20986 | SCR_008151 | U.S. Pig Genome Project | 2026-08-21 12:38:30 | 0 | |||||||||
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Comparative Saccharinae Genomics Resource Resource Report Resource Website |
Comparative Saccharinae Genomics Resource (RRID:SCR_008153) | data or information resource, data processing software, database, image processing software, portal, software application, software resource, topical portal | The objective of this project is to develop physical maps of the sorghum and rice genomes, based on BAC contigs that are cross-linked to each other and also to genetic maps and BAC islands for other large-genome crops and a library of ca. 50,000 expressed-sequence tags (EST''s) and corresponding cDNA clones, from diverse sorghum organs and developmental states. It also aims to improve understanding of genetic diversity and allelic richness that might be harbored ex situ (in gene banks) or in situ (in nature), and refine techniques for assesing allelic richness and Expedite data acquisition and utilization by a sound parnership between laboratory scientists and computational biologists. Specific goals of developing physical maps of sorghum and rice genomes include: -Enrich cross-links between sorghum and rice by mapping additional rice probes on sorghum. -Apply mapped DNA probes to macroarrays of sorghum, sugarcane, rice, and maize BACs. -Fingerprint 10x BAC libraries of Sorghum bicolor and S. propinquum. Libraries presently 3x and 6x respectively, to be expanded to 10x each. -Use fragment-matching (BAC-RF) method to determine locus-specificity in polyploids. - Contig assembly based on 1-3, plus rice BAC fingerprints generated under a separate Novartis project. -Evaluate methodology for rapid high-throughput assignment of new ESTs to BACs. -Conduct genomic sequencing in a region duplicated in both sorghum and arabidopsis. Selected BACs from sorghum(2), sugarcane, maize, rice, wheat. By improving the understanding of genetic diversity and allelic richness, the goal is to: -Sequence previously mapped sorghum DNA probes. -Discover & characterize 100 single nucleotide polymorphisms (SNPs) from cDNA markers. -Develop colorimetric high-throughput genotyping assays, and utilize to assess genetic diversity in geographically- and phenotypically-diverse sorghums. -Develop colorimetric high-throughput asssays for identifying phytochrome allelic variation, and apply these assays to a core collection representing a large set of genetic resources. -Support informatics group to streamline cataloging of DNA-level information relevant to large genetic resources collections. Lastly, the goals of expediting data acquisition and utilization include: -A new web-based resource for 3D-integration and visualization of structural and functional genomic data will be developed. -New sequence assembly and alignment software SABER (Sequence AssemBly in the presence of ERror), and PRIMAL(Practical RIgorous Multiple ALignment), will be evaluated with reference to existing standards (PHRED, PHRAP). -Specialized image processing and image analysis tools will be developed for acquistion and interpretation of qualitative and quantitative hybridization signals. To deal expeditiously with large volumes of data, parallel processing approaches will be investigated. Sponsors: * National Science Foundation (NSF) * National Sorghum Producers * University of Georgia Research Foundation (UGARF) * Georgia Research Alliance (GRA) | fingerprint, genetic, alignment, allele, allelic, arabidopsis, bac, biologist, cdna, clone, colorimetric, computational, contig, crop, diverse, diversity, dna, genome, genotyping, locus, macroarray, maize, map, marker, nucleotide, organ, phenotypically, physical, phytochrome, polymorphism, polyploid, probe, rice, sorghum, sugarcane, undergraduate, wheat, k-12 program | has parent organization: University of Georgia; Georgia; USA | nif-0000-20996 | http://csgr.agtec.uga.edu/ | SCR_008153 | CSGR | 2026-08-21 12:38:36 | 0 | ||||||||
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AraCyc Resource Report Resource Website 50+ mentions |
AraCyc (RRID:SCR_008109) | data or information resource, data repository, database, service resource, storage service resource | Curated species-specific database present at the Plant Metabolic Network. It has a large number of experimentally supported enzymes and metabolic pathways, but it also houses a substantial number of computationally predicted enzymes and pathways. | enzyme, gene, arabidopsis thaliana, biochemical, pathway, reaction, metabolism, metabolic pathway, data set, data analysis service, web service, FASEB list |
is used by: Arabidopsis Reactome is listed by: 3DVC has parent organization: Plant Metabolic Network |
NSF | PMID:12805578 PMID:15888675 |
The community can contribute to this resource | nif-0000-20811 | http://www.arabidopsis.org/biocyc/index.jsp, http://www.plantcyc.org | SCR_008109 | Arabidopsis enzymes and biochemical pathways database | 2026-08-21 12:38:34 | 69 | |||||
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ActiveDriver Resource Report Resource Website 10+ mentions |
ActiveDriver (RRID:SCR_008104) | ActiveDriver | data analysis software, data processing software, sequence analysis software, software application, software resource | A statistical method for interpreting variations in protein sequence (e.g. coding SNPs in the population, SNVs in cancer genomes) in the context of protein post-translational signaling modifications. | Protein sequence variation, variation interpretation, protein sequence, protein post-translational signaling modifications, bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools |
Free, Available for download, Freely available | biotools:ActiveDriver, OMICS_00140 | http://reimandlab.org/software/activedriver/, https://cran.r-project.org/web/packages/ActiveDriver/ActiveDriver.pdf, https://bio.tools/ActiveDriver | SCR_008104 | 2026-08-21 12:38:28 | 27 | |||||||
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Department of Psychiatry, Turner Laboratory Resource Report Resource Website |
Department of Psychiatry, Turner Laboratory (RRID:SCR_008067) | Turner Lab | data or information resource, laboratory portal, organization portal, portal | Dr. Eric Turner''s laboratory studies the mechanisms underlying the development of the nervous system. The vertebrate brain is comprised of a tremendous variety of neurons, each class exhibiting a unique phenotype characterized by the expression of specific neurotransmitter receptors, ion channels, patterns of axonal growth, and synapse formation. The research we conduct focuses on the critical role transcription factors play in the specification of neuronal cell type during development. We are particularly interested in transcription factors of the homeodomain family that bind to DNA and in doing so activate or repress gene expression. One area of study is the role of POU-domain transciption factor Brn3a in axon growth and survival. The primary research areas are: * Neuronal cell fate determination: The expression of regulatory genes is manipulated in living chick embryos using microsurgery and electroporation and the effects on neural marker genes studied. * Molecular mechanisms of gene regulation: Target DNA binding sites of neural transcription factors are biochemically characterized and findings coordinated with sequence data from the mouse and human genomes. * Targeted misexpression of regulatory genes: Transgenic and knockout mouse technology is used to misexpress genes of interest, and the effects on neural marker genes, axonal growth, and cell survival studied. * Global analysis of neural gene expression: Micro-arrays (GeneChips) are employed in conjunction with other areas of study to understand the coordinated regulation of gene expression in the nervous system. Dr. Turner is a member of the University of California, San Diego''s Graduate Program in Neuroscience and Biomedical Sciences Program and accepts students from these two programs. Interesting rotation projects are available using methods ranging from biochemistry and molecular biology to embryology. Additionally, Dr. Turner is also the Director of this NIMH-funded training program for research-oriented psychiatrists, psychologists, and basic neuroscientists working in areas relevant to psychiatry. Typically Fellows spend two years in the program, during which they develop a research project under the close supervision of one of the highly productive members of the UCSD Department of Psychiatry, or another investigator in the La Jolla (UCSD/Salk/Scripps) research community. | electroporation, embryo, embryology, expression, gene, axon, biochemistry, biomedical science, cell, c hick, development, dna, dna binding site, homeodomain, human, knockout technology, microarray, microsurgery, misexpression, molecular biology, molecular mechanism, mouse, nervous system, neural gene, neural marker gene, neural transcription factor, neuronal cell, neuroscience, neuroscientist, psychiatrist, psychologist, regulation, regulatory gene, transcription factor, transgenic technology | has parent organization: University of California at San Diego Department of Psychiatry | nif-0000-10507 | SCR_008067 | UCSD Turner Laboratory, UCSD Psychiatry (Turner''s Lab), Turner Laboratory, Turner Laboratory Developmental Neurobiology Research | 2026-08-21 12:38:33 | 0 | ||||||||
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EDGE: Environment, Drugs and Gene Expression Resource Report Resource Website 10+ mentions |
EDGE: Environment, Drugs and Gene Expression (RRID:SCR_008187) | EDGE | analysis service resource, biomaterial analysis service, data or information resource, experimental protocol, material analysis service, narrative resource, production service resource, service resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 15, 2013. EDGE is a scientific resource for toxicology-related gene expression information. The site contains databases and analyses of gene expression studies following exposure to a variety of chemicals or physiological changes. The ultimate goal of the EDGE is to map transcriptional changes from chemical exposure that will someday be used as a diagnostic fingerprint to predict toxicity as well as provide valuable insights into the basic molecular changes responsible. EDGE gives you the ability to easily answer the following fundamental questions about your data 1. Can I compare transcriptional profiles across treatments? 2. What genes respond to my treatment? 3. What influences my favorite gene(s)? One of the major objectives of toxicology is to understand the adverse health effects that result from exposure to foreign chemicals. The traditional method for assessing the toxicity of a test chemical is very resource intensive; requiring the commitment of large amounts of money, time, and animals. According to the National Toxicology Program (NTP), each chemical study requires between 2 and 4 million dollars and several years to complete. Due to the cost and labor intensive nature of these studies, the number of chemicals currently tested by the NTP stands at less than 500. Given these statistics and the fact that there are approximately 70,000 chemicals in commerce today, it is increasingly apparent that alternative methods for assessing toxic potential must be explored if a significant portion of the remaining chemicals is to be tested. One potential solution is to develop a comprehensive database that describes alterations in gene expression resulting from chemical exposure. The pattern of transcriptional activity will not only be highly sensitive indicator of chemical exposure, but that this pattern will be diagnostic for mechanistically linked toxicants. In our laboratory, we have chosen to address this problem through a combination of high throughput sequencing of expressed sequence tags (ESTs) and construction of custom toxicology-related cDNA microarrays derived from the unique ESTs identified in the sequencing effort. By using this approach, we can simultaneously develop a quantitative gene expression profile using ESTs and the reagents for further analyzing these changes in a rapid, highly parallel manner. In addition, the expression profiles are not biased for preselected favorite genes. The resulting gene expression pattern can then be used as diagnostic fingerprint to predict toxicity and/or carcinogenicity as well as provide valuable insight into the basic biochemical and molecular changes responsible for toxicity. Submission of total RNA for Bradfield Lab Microarray Microarray comparisons are made between untreated, control animals and animals treated with ONE treatment. Please make sure the RNA submitted adheres to this experimental design. Necessary information is available on the site. | expressed sequence tags (ests), gene expression, gene expression profile, genes, alterations, cdna microarray, chemical exposure, predictive statistical models, sequencing, toxicogenomics, toxicology, transcriptional changes | has parent organization: University of Wisconsin-Madison; Wisconsin; USA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-21140 | SCR_008187 | Drugs and Gene Expression, Environment | 2026-08-21 12:38:36 | 13 | |||||||
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Foundational Model Explorer Resource Report Resource Website 1+ mentions |
Foundational Model Explorer (RRID:SCR_008189) | data analysis software, data processing software, software application, software resource | The Foundational Model Explorer (FME) is an internet based software application developed for viewing the content and organization of the Foundational Model of Anatomy Ontology (FMA). The initial purpose of the FME was to provide a simple and intuitive interface to the FMA for domain experts, in the field of anatomy, participating in the evaluation of the FMA. The FME also provides an easily available method of exploring the FMA to individuals or groups considering the adoption of the Foundational Model of Anatomy knowledge base. The FME display consists of two panes: a hierarchical tree may be opened up in the pane on the left side; if a class is selected in the hierarchical tree, the pane on the right side displays the information that has been entered in the FMA for that class. The information associated with a given class is organized in so-called slots. Each slot has a name (e.g., Definition, Parts) and some content, which is that particular slots value (e.g., the English definition and the names of parts of the selected class, respectively). For an explanation of the interactive features of the FME, see the Knowledge Navigation Section. For a guided tutorial check out the Conducted Tour. In the left pane, the default tree is a subclass hierarchy, based on the -is a- or -kind of- relationship; it is the instantiation of the Anatomy taxonomy (At) component in the high level scheme of the Foundational Model of Anatomy. Apart from the slots Preferred Name and Synonyms, other slots relate to the Anatomical Structural Abstraction (ASA) component in the FMAs high level scheme. Hierarchies based on various part-whole relationships can also be opened up in the left pane. Once a class has been highlighted in the subclass hierarchy, you can choose a relationship from a drop down list labeled Select navigation tree type. Some other transitive relationships (e.g., -branch of- and -tributary of-) are also available. The Search facility matches a search term to the preferred name, as well as to the Latin name, or synonym of an FMA class (if such exist). The tree is expanded to reveal the matching class and the information about this class is displayed. The wildcard * is allowed in the search term and will match to any sequence of characters. For example the search term h*d matches the class names Head and Hepatic cord (amongst others). The search function is not case sensitive. If more than one class name matches with the search term, a list of matching terms is presented for the user to choose between. | foundational, anatomical, anatomist, anatomy, anatomy databases, class, component, content, digital, hierarchical tree, model, organization, relationship, software, structural, subclass, taxonomy | has parent organization: University of Washington; Seattle; USA | nif-0000-21156 | SCR_008189 | FME | 2026-08-21 12:38:31 | 1 | |||||||||
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GeneWindow Resource Report Resource Website 1+ mentions |
GeneWindow (RRID:SCR_008183) | data analysis software, data processing software, software application, software resource | Software tool for pre- and post-genetic bioinformatics and analytical work, developed and used at the Core Genotyping Facility (CGF) at the National Cancer Institute. While Genewindow is implemented for the human genome and integrated with the CGF laboratory data, it stands as a useful tool to assist investigators in the selection of variants for study in vitro, or in novel genetic association studies. The Genewindow application and source code is publicly available for use in other genomes, and can be integrated with the analysis, storage, and archiving of data generated in any laboratory setting. This can assist laboratories in the choice and tracking of information related to genetic annotations, including variations and genomic positions. Features of GeneWindow include: -Intuitive representation of genomic variation using advanced web-based graphics (SVG) -Search by HUGO gene symbol, dbSNP ID, internal CGF polymorphism ID, or chromosome coordinates -Gene-centric display (only when a gene of interest is in view) oriented 5 to 3 regardless of the reference strand and adjacent genes -Two views, a Locus Overview, which varies in size depending on the gene or genomic region being viewed and, below it, a Sequence View displaying 2000 base pairs within the overview -Navigate the genome by clicking along the gene in the Locus Overview to change the Sequence View, expand or contract the genomic interval, or shift the view in the 5 or 3 direction (relative to the current gene) -Lists of available genomic features -Search for sequence matches in the Locus Overview -Genomic features are represented by shape, color and opacity with contextual information visible when the user moves over or clicks on a feature -Administrators can insert newly-discovered polymorphisms into the Genewindow database by entering annotations directly through the GUI -Integration with a Laboratory Information Management System (LIMS) or other databases is possible | gene, genetic, analysis, annotation, archive, bioinformatic, cancer, genome, genomic, genotype, genotyping, human, human genome databases, maps, polymorphism, position, variation, data set |
is listed by: 3DVC has parent organization: National Cancer Institute |
nif-0000-21173 | SCR_008183 | GeneWindow | 2026-08-21 12:38:36 | 1 | |||||||||
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University of Texas at San Antonio Laboratory of Professor Brenda Claiborne Resource Report Resource Website 1+ mentions |
University of Texas at San Antonio Laboratory of Professor Brenda Claiborne (RRID:SCR_008064) | UTSA Claiborne Lab | data or information resource, data set, laboratory portal, organization portal, portal | The long-term goals of my research are to understand the relationship between neuronal structure and function, and to elucidate the factors that affect neuronal morphology and function over the lifespan of the mammal. Currently we are examining 1) the effects of synaptic activity on neuronal development; 2) the effects of estrogen on neuronal morphology and on learning and memory; and, 3) the effects of aging on neuronal structure and function. We have focused our efforts on single neurons in the hippocampal formation, a region that is critical for certain forms of learning and memory in rodents and humans. From the portal, you may click on a cell in your region of interest to see the complete database of cells from that region. You may also explore the Neuron Database: * Comparative Electrotonic Analysis of Three Classes of Rat Hippocampal Neurons. (Raw data available) * Quantitative, three-dimensional analysis of granule cell dendrites in the rat dentate gyrus. * Dendritic Growth and Regression in Rat Dentate Granule Cells During Late Postnatal Development.(Raw data available) * A light and electron microscopic analysis of the mossy fibers of the rat dentate gyrus. | neuronal, structure, synaptic activity, rodent, human, neuron, neuronal morphology, synapse, neuronal development, learning, memory, estrogen, hippocampus, hippocampal formation, mammal, cell | has parent organization: University of Texas at San Antonio; Texas; USA | Aging | nif-0000-10481 | SCR_008064 | USTA Laboratory of Professor Brenda Claiborne | 2026-08-21 12:38:27 | 1 |
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