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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://ls-snp.icm.jhu.edu/ls-snp-pdb/
A web tool for genome-wide annotation of human SNPs.
Proper citation: LS-SNP/PDB (RRID:SCR_010774) Copy
http://www.nitrc.org/projects/jhucis_pedatlas/
Anatomical atlases constructed by Computational Anatomy of Johns Hopkins University for analysis of shape vectors. The atlases were generated from segmented hippocampal and amygdala structures in acquired populations of children, adolescents and young adults in neuroimaging studies of major depression disorder (MDD) at Washington University at St Louis.
Proper citation: Atlases of amygdala and hippocampus for pediatric populations (RRID:SCR_014085) Copy
http://ccb.jhu.edu/software/FLASH/
Open source software tool to merge paired-end reads from next-generation sequencing experiments. Designed to merge pairs of reads when original DNA fragments are shorter than twice length of reads. Can improve genome assemblies and transcriptome assembly by merging RNA-seq data.
Proper citation: FLASH (RRID:SCR_005531) Copy
http://psychiatry.igm.jhmi.edu/SynaptomeDB/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Ontology-based knowledgebase for synaptic genes. These genes encode components of the synapse including neurotransmitters and their receptors, adhesion / cytoskeletal proteins, scaffold proteins, transporters, and others. It integrates various and complex data sources for synaptic genes and proteins., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: SynaptomeDB (RRID:SCR_000157) Copy
http://sourceforge.net/projects/blox/
A quantitative medical imaging and visualization program for use on brain MR, DTI, and MRS data. Programming Language: Java, JavaScript, Scheme
Proper citation: Blox (RRID:SCR_006667) Copy
Perform clinical, epidemiological, and therapeutic research in gastroparesis and provide an infrastructure that can rapidly and efficiently design and conduct clinical trials for effective medical, surgical, or other interventions to improve treatment of patients with gastroparesis. The GpCRC studies comprise well characterized individuals with diabetic, surgical, and idiopathic gastroparesis.
Proper citation: Gastroparesis Clinical Research Consortium (RRID:SCR_006673) Copy
http://www.roselab.jhu.edu/coil/
The Protein Coil Library is a library of protein structure fragments derived from the Protein Data Bank (PDB). The fragments in this library are those fragments in the PDB that cannot be classified as either alpha-helix or beta-strand. Three-dimensional structures as well as side-chain and backbone torsion angles are stored in the database. The Protein Coil Library allows rapid and comprehensive access to non-alpha-helix and non-beta-strand fragments contained in the Protein Data Bank (PDB). The library contains both sequence and structure information together with calculated torsion angles for both the backbone and side chains. Several search options are implemented, including a query function that uses output from popular PDB-culling servers directly. Additionally, several popular searches are stored and updated for immediate access. The library is a useful tool for exploring conformational propensities, turn motifs, and a recent model of the unfolded state. The library stores the complete torsion angle descriptions for the fragments as well as the three dimensional structures of the fragments themselves. The goal of extracting and pre-calculating this data is to allow for more straightforward investigation of peptide structure without the background of secondary structure elements. In addition to searching by PDB ID, it is possible to download a particular size class, perform a batch search of PDB/chain ID''s, or download precompiled lists of PDB ID''s of interest (PDB Select, etc.). For users interested in browsing the entire database at once or maintaining their own locally-updated copy of the library, FTP access instructions are also provided. The files stored in the coil library FTP site or returned after a batch search are organized heirarchically by PDB ID. This is done to reduce filesystem access times and fascilitate searches using the UNIX find utility. At the lowest directory level in the heirarchy, files are further sorted by fragment length. As a result, the number of files in a particular directory is generally less then 50, yielding relatively fast access on UNIX/Linux filesystems. The heirarchical organization is based on the middle two letters of the PDB ID. For example, hen egg lysozyme, which has a PDB ID of 1HEL, will be located in the directory h/he/. At the final level, fragments of varying sizes are stored in directories that correspond to their fragment length. Again, using lysozyme as an example, any seven-residue fragments, if they exist, will reside in the directory h/he/7/. Similarly, seven-residue fragments from 2HEX and 1HE0 will also be in this location. Sponsors: The Protein Coil Library is funded by Johns Hopkins University.
Proper citation: The Protein Coil Library (RRID:SCR_008233) Copy
http://experimentalman.com/blog/
Blog about how leading-edge bio-science and technology is impacting individuals and society. This blog is an outgrowth of David Ewing Duncan''s new book, Experimental Man: What one mans body reveals about youy future, your health, and our toxic world. In the book he reports taking over 250 tests in the realms of genes, environment, brain and body and explore what these tests can tell us about one persons health, past, present, and future.
Proper citation: Experimental Man Blog (RRID:SCR_008378) Copy
Purpose of the Myc Hubsite The emergence of complex DNA microarray data on gene expression creates vast new opportunities but also poses serious challenges for information and library sciences. This complexity becomes more challenging as certain genes, such as MYC that encodes a transcription factor, switch on other genes. The purpose of this website is to provide a hub for the integration of information on Myc target genes, the role of Myc in human cancers, and proteins that interact with the Myc transcription factors. Links are provided that connect to PUBMED citations, Unigene database, and in specific cases to original data. Sponsor: Funded by a grant from the National Library of Medicine
Proper citation: MYC Cancer Gene (RRID:SCR_008608) Copy
http://www.nitrc.org/projects/jist/
A native Java-based imaging processing environment similar to the ITK/VTK paradigm. Initially developed as an extension to MIPAV (CIT, NIH, Bethesda, MD), the JIST processing infrastructure provides automated GUI generation for application plug-ins, graphical layout tools, and command line interfaces. This repository maintains the current multi-institutional JIST development tree and is recommended for public use and extension. JIST was originally developed at IACL and MedIC (Johns Hopkins University) and is now also supported by MASI (Vanderbilt University).
Proper citation: JIST: Java Image Science Toolkit (RRID:SCR_008887) Copy
It was created to serve as a gateway to alternatives news, information, and resources on the Internet and beyond. Altweb now is the U.S. home of the journal ALTEX: Alternatives to Animal Experimentation, which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). Altweb is intended to serve: *Biomedical researchers *Industry *The international alternatives community *The international regulatory community(ies) *IACUCs and other institutional groups that review animal protocols *The animal welfare community *Individuals and groups who work with laboratory animals (technicians, veterinarians, etc.) *Educators *Students *The general public Altweb has five practical goals: 1. To assist scientists and others seeking to conduct a search for alternatives methods. 2. To serve as a CRPcentral reference pointfor alternatives information, publications, databases, calendars, and other resources. 3. To support the creation and maintenance of new alternative resources as needed, when no other organization can/will do so. 4. To promote the use of alternatives resources by publicizing them on the site and through e-mail or other outreach. 5. To facilitate communication and collaboration among members of the alternatives community, in particular those who work in database or information management.
Proper citation: Atlweb: Alternatives to Animal Testing (RRID:SCR_007265) Copy
Center for Computational Biology as a joint research center in the McKusick-Nathans Institute of Genetic Medicine, spanning the School of Medicine, the Whiting School of Engineering, the Bloomberg School of Public Health, and the Krieger School of Arts & Sciences. Multidisciplinary center dedicated to research on genomics, genetics, DNA sequencing technology, and computational methods for DNA and RNA sequence analysis.
Proper citation: Center for Computational Biology at JHU (RRID:SCR_016680) Copy
http://www.nitrc.org/projects/longitudinal_ms/
The Longitudinal MS Lesion Imaging Archive provides Training data consisting of longitudinal images from five patients and Testing data consisting of 15 patients. Each longitudinal dataset includes T1-weighted, T2-weighted, PD-weighted, and T2-weighted FLAIR MRI with 3-5 time points acquired on a 3T MR scanner. T1-weighted images have approximately a 1mm cubic voxel resolution, while the other scans are 1mm in plane with 3mm sections. Accounting for the multiple time points, this constitutes approximately 80 individual data sets. The Training data contains manual segmentations of the MS lesions from two different raters for each of the time points provided.
Proper citation: Longitudinal MS Lesion Imaging Archive (RRID:SCR_014136) Copy
Provides leadership in biomedical research on animal and human diseases and assists with the health and humane care of research animals within the institution.
Proper citation: Johns Hopkins School of Medicine Department of Molecular and Comparative Pathobiology (RRID:SCR_008297) Copy
An on-going project and collaboration tool where biomedical researchers can access to expertise and related resources across institutions, regardless of local platforms and tools. Users can work with participating institutions in order to connect to their existing research networking tools. Biomedical institutions that wish to participate must have a mature, deployed research networking tool and can commit resources to assessments.
Proper citation: DIRECT2experts (RRID:SCR_013958) Copy
Project portal dedicated to understand animal and machine intelligence and repository of data and tools. Suite of tools to analyze and graph imaging data. Image and data repository for large, publicly available neuro-specific data files and images. Contains tools for analytics, databases, cloud computing, and Web-services applied to both big neuroimages and big neurographs.
Proper citation: neurodata (RRID:SCR_014264) Copy
https://diabetescenters.org/centers
Diabetes Research Centers (DRC) is an integrated program of diabetes, endocrinology and metabolism research.
Proper citation: Diabetes Research Centers (RRID:SCR_014535) Copy
http://www.nitrc.org/projects/dots/
A fast, scalable tool developed at the Johns Hopkins University to automatically segment the major anatomical fiber tracts within the human brain from clinical quality diffusion tensor MR imaging. With an atlas-based Markov Random Field representation, DOTS directly estimates the tract probabilities, bypassing tractography and associated issues. Overlapping and crossing fibers are modeled and DOTS can also handle white matter lesions. DOTS is released as a plug-in for the MIPAV software package and as a module for the JIST pipeline environment. They are therefore cross-platform and compatible with a wide variety of file formats.
Proper citation: DOTS WM tract segmentation (RRID:SCR_009459) Copy
http://ccb.jhu.edu/software/glimmer/index.shtml
A software system for finding genes in microbial DNA, especially the genomes of bacteria, archaea, and viruses.
Proper citation: Glimmer (RRID:SCR_011931) Copy
http://www.scienceexchange.com/facilities/johns-hopkins-university
An Portal, Core facility
Proper citation: Johns Hopkins University Labs and Facilities (RRID:SCR_012375) Copy
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