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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.creative-peptides.com/services/peptide-drug-bioconjugations.html
Custom peptide synthesis, modification, and conjugation services involve chemical modification of peptide at highly specific sites. This allows for attachment of drugs or bioactive molecules though variety of coupling techniques.
Proper citation: Creative Peptides Peptide Drug Bioconjugations Service Resource (RRID:SCR_022221) Copy
https://github.com/Benson-Genomics-Lab/TRF
Software tool to locate and display tandem repeats in DNA sequences. Used to analyze DNA sequences.
Proper citation: Tandem Repeats Finder (RRID:SCR_022065) Copy
Viewer for DNA Methylation Atlas of Mouse Brain at Single Cell Resolution. Browser to interactively explore single cell methylome dataset including exploration of methylation diversity of one gene at single-cell or cell-type level, exploration of cell type composition of adult mouse brain dissection regions and anatomical structures, explorartion of spatial distribution and methylation signature genes of one cell type.
Proper citation: Brain Cell Methylation Viewer (RRID:SCR_020954) Copy
https://www.creative-peptides.com/services/total-peptide-library-construction-technology.html
Service uses bioinformatics methods to compress peptide information, which can integrate information of multiple peptide into one peptide. Provides collection of small peptide of specific length and different sequences, which includes permutation and combination of various amino acid sequences in short peptide of this length.Total peptide library for new drug research and development.
Proper citation: Creative Peptides Total Peptide Library Construction Service Resource (RRID:SCR_022219) Copy
https://mass-spec.stanford.edu/instruments
System includes SQD2 as single quadrupole MS with Waters H-Class Acquity UPLC, operated as open access platform for trained users. SQ Detector2 is single quadrupole mass detector for chromatography compatible with range of chromatography platforms and ionization sources.
Proper citation: Waters: SQD2 LC/MS system (RRID:SCR_022217) Copy
http://old.protein.bio.unipd.it/cspritz/
Web tool for prediction of intrinsic protein disorder segments with annotation for homology, secondary structure and linear motifs.
Proper citation: CSpritz (RRID:SCR_021884) Copy
Software application to organize and store in structured format signaling information published in scientific literature. Information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. Each relationship is linked to literature reporting experimental evidence. Each node is annotated with chemical inhibitors that modulate its activity. Signaling information is mapped to human proteome. SIGNOR 2.0 stores manually annotated causal relationships between proteins and other biologically relevant entities including chemicals, phenotypes, complexes, etc with compliance to FAIR data principles.
Proper citation: SIGNOR (RRID:SCR_018485) Copy
https://shimadzu.com.au/labsolutions
Software package for data analysis by Shimadzu Oceania.
Proper citation: LabSolutions (RRID:SCR_018241) Copy
https://software.broadinstitute.org/cancer/cga/polysolver
Software tool for HLA typing based on whole exome sequencing data and infers alleles for three major MHC class I genes. Enables accurate inference of germline alleles of class I HLA-A, B and C genes and subsequent detection of mutations in these genes using inferred alleles as reference.
Proper citation: Polysolver (RRID:SCR_022278) Copy
https://github.com/mrcgndr/plant_cataloging_workflow
Software workflow for automatized spatio temporal plant positioning based on UAV images.
Proper citation: Plant Cataloging Workflow (RRID:SCR_022276) Copy
https://pathology.med.upenn.edu/research/core-resources/tumor-tissue-biospecimen-bank
Centralized biorepository of human biosamples. TTAB is responsible for the collection, processing, and storage of human blood, fluid, and tissue at the University of Pennsylvania Health System. TTAB has a collection bench within Surgical Pathology Suite at Hospital of University of Pennsylvania (HUP).� Our collection bench sits adjacent to frozen section teams managing clinical sample collection and allowing for tight integration of tissue sample collection with clinical pathology teams.
Proper citation: University of Pennsylvania Perelman School of Medicine Tumor Tissue Biospecimen Bank Core Facility (RRID:SCR_022430) Copy
https://maayanlab.cloud/sigcom-lincs
Web server that serves over million gene expression signatures processed, analyzed, and visualized from LINCS, GTEx, and GEO. Data and metadata search engine for gene expression signatures.
Proper citation: SigCom LINCS (RRID:SCR_022275) Copy
Web service for RNA/DNA folding predictions including pseudoknots and entangled helices.Used for prediction and statistics of pseudoknots in RNA structures using exactly clustered stochastic simulations.
Proper citation: KineFold (RRID:SCR_022273) Copy
https://www2.hhu.de/rna/html/hexplorer_score.php
Web tool for genomic HEXploring allows landscaping of novel potential splicing regulatory elements. Allows landscaping of splicing regulatory regions, provides quantitative measure of mutation effects on splice enhancing and silencing properties and permitts calculation of mutationally most effective nucleotide.
Proper citation: HEXplorer score (RRID:SCR_022269) Copy
http://www.codons.org/calc.html
Software tool for calculating and comparing synonymous codon usage and its impact on protein folding. Used to harmonize codon usage frequencies for heterologous gene expression. Codon usage calculator that evaluates relative usage frequencies of synonymous codons used to encode protein sequence of interest and compares these results to rigorous null mode.Evaluates synonymous codon usage patterns for any coding sequence from any fully sequenced genome.
Proper citation: %MinMax (RRID:SCR_022268) Copy
http://hub.docker.com/r/marchalc/hicres/
Software pipeline to estimate and predict genomic resolution of Hi-C libraries. Used for estimating and predicting HiC library resolution.
Proper citation: HiCRes (RRID:SCR_022319) Copy
https://github.com/FRED-2/OptiType
Software tool for precision HLA typing from next generation sequencing data.
Proper citation: OptiType (RRID:SCR_022279) Copy
https://www.med.upenn.edu/ifi/cytofservicecenter.html
CyTOF�enables multi-parametric high-dimensional single�cell analysis�of more than 40 markers per cell, with�minimal background and compensation�issues.�Core�offers variety of�CyTOF-related services including�reagent distribution, consultation,�antibody conjugation, and data acquisition.�
Proper citation: University of Pennsylvania Perelman School of Medicine IFI CyTOF Service Center Core Facility (RRID:SCR_022410) Copy
https://github.com/B-UMMI/LMAS
Automated workflow enabling benchmarking of traditional and metagenomic prokaryotic de novo assembly software using defined mock communities. Results are presented in interactive HTML report where selected global and reference specific performance metrics can be explored.
Proper citation: LMAS (RRID:SCR_022251) Copy
https://github.com/bpucker/KIPEs
Software tool as automatic approach for identification of players in biosynthesis pathway. Used for automatic annotation of flavonoid biosynthesis steps in new transcriptome of genome sequence assembly. Various enzymes of entire metabolic networks can be identified if sufficient knowledge about functionally relevant amino acids is available.Combines comprehensive sequence similarity analyses with inspection of functionally relevant amino acid residues and domains in subjected peptide sequences.
Proper citation: Knowledge based Identification of Pathway Enzymes (RRID:SCR_022370) Copy
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