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https://clinicaltrials.gov/study/NCT01885559

Consortium established to design and implement clinical trials of treatments that might slow the progressive loss of renal function in Polycystic Kidney Disease (PKD). Two multicenter randomized, double-blind, placebo controlled clinical trials are running concurrently to study the efficacy of renin-angiotensin-aldosterone system blockade on the progression of cystic disease (kidney volume) and on the decline in renal function in autosomal dominant polycystic kidney disease (ADPKD). Study A is to study whether intensive ACE-I/ARB blockade decrease the progression of cystic disease compared to ACE-I monotherapy patients with early disease, relatively preserved renal function, and high-normal BP or hypertension. Study B is to study whether intensive ACE-I/ARB blockade as compared to ACE-I monotherapy slow the decline in kidney function, end-stage of renal disease, or death in the setting of standard blood pressure control in hypertensive patients with moderately advanced disease.

Proper citation: HALT PKD (RRID:SCR_001529) Copy   

•   Source: SciCrunch Registry
  

http://www.radiology.ucsf.edu/research/labs/hyperpolarized-mri-tech

Biomedical technology research center developing, investigating, and disseminating new hyperpolarized MR techniques, new 13C agents and specialized analysis open-source software for data reconstruction and interpretation. The Technology Research & Development projects will leverage the extensive DNP facilities and experience of the project leaders to develop improved, robust hyperpolarized MRI methods. These technology developments will be driven by Collaborative Projects led by outstanding clinical and basic scientists who aim to use hyperpolarized 13C MRI to accomplish the scientific goals of their funded research. These technical developments will also be disseminated to the Service Project investigators for extramural feedback and then widely to the scientific community via a dedicated website and onsite training. This center will provide state-of-the-art training in this new metabolic imaging field and sponsor a yearly symposium focused on hyperpolarized MR technology development.

Proper citation: Hyperpolarized MRI Technology Resource Center (RRID:SCR_001405) Copy   

•   Source: SciCrunch Registry
  

http://neomorph.salk.edu/brain_methylomes/

THIS RESOURCE IS NO LONGER IN SERVICE. Datasets described in the manuscript: "Global Epigenomic Reconfiguration During Mammalian Brain Development" (Science, 2013 - DOI: 10.1126/science.1237905. This study provides genome-wide composition, patterning, cell specificity, and dynamics of DNA methylation at single-base resolution in human and mouse frontal cortex throughout their lifespan. Widespread methylome reconfiguration occurs during fetal to young adult development, coincident with synaptogenesis.

Proper citation: Mammalian Brain Methylomes (RRID:SCR_001648) Copy   

•   Source: SciCrunch Registry
  

https://www.nitrc.org/projects/nitrc_es

An on-demand, cloud based computational virtual machine pre-installed with popular NITRC neuroimaging tools built using NeuroDebian. For a listing of current NITRC-CE packages visit: http://www.nitrc.org/ce-packages. You can also use the "public Amazon Machine Interface (AMI)" to conduct your analyses on the Amazon EC2 platform.

Proper citation: NITRC Computational Environment (RRID:SCR_002171) Copy   

•   Source: SciCrunch Registry
  

http://www.sanger.ac.uk/science/tools/ssaha2-0

A program designed for the efficient mapping of sequence reads onto genomic references. The software is capable of reading most sequencing platforms and giving a range of outputs are supported.

Proper citation: Sequence Search and Alignment by Hashing Algorithm (RRID:SCR_000544) Copy   

•   Source: SciCrunch Registry
  

http://www.isletstudy.org/

Network of centers to conduct studies of islet transplantation in patients with type 1 diabetes to improve the safety and long-term success of methods for transplanting islets. It is the aim of this trial to improve methods of isolating islets, to improve techniques for the administering those transplanted islets; and to develop approaches to minimize the toxic effects of immunosuppressive drugs required for transplantation.

Proper citation: Clinical Islet Transplantation Study (RRID:SCR_001515) Copy   

•   Source: SciCrunch Registry
  

http://blog.wholebraincatalog.org/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 6,2023. The blog of the Whole Brain Catalog.

Proper citation: Whole Brain Catalog Blog (RRID:SCR_000582) Copy   

•   Source: SciCrunch Registry
  

http://decgpu.sourceforge.net/homepage.htm

Software tool as parallel and distributed error correction algorithm for high-throughput short reads using CUDA and MPI parallel programming models.

Proper citation: DecGPU (RRID:SCR_000585) Copy   

•   Source: SciCrunch Registry
  

http://grigoriefflab.janelia.org/rejections

Repository of rejections of papers - letters and comments - that were ultimately accepted by a journal to educate others. Your rejection letters and comments are welcome. Some journals have begun including reviewers' comments with accepted papers to make the views of experts available to the reader. However, often the paper has been submitted to several journals and rejected before it is finally accepted. The rejection letters and comments are equally useful in helping to judge what kind of papers might be acceptable to a journal, and what kind of comments lead to rejections. Rather than hiding these low points in the trajectory of a scientific paper, this forum offers a place to publish these letters and comments to educate others.

Proper citation: Paper Rejection Repository (RRID:SCR_002643) Copy   

•   Source: SciCrunch Registry
  

http://www.bioinf.uni-leipzig.de/Software/RNAplex/

Software tool to rapidly search for short interactions between two long RNAs.

Proper citation: RNAplex (RRID:SCR_002763) Copy   

•   Source: SciCrunch Registry
  

http://www.ibgm.med.uva.es/files/upload/manual/casyoperatormanual.pdf

Tool for the qualitative and quantitative assessment of cell cultures including standardized cell counting methods, viability checks, aggregation correction, volumetric measurement with high measuring range dynamics. It enables to create optimal settings for measuring certain cell population numbers (based on size and gating strategies).

Proper citation: CASY Cell Counter and Analyser System Model TT (RRID:SCR_002080) Copy   

•   Source: SciCrunch Registry
  

http://www.raraf.org/

Biomedical technology research center dedicated for radiobiological research with available ionizing radiations such as protons, alpha particles, and neutrons. RARAF is well-established and highly user-friendly. The focus of RARAF is the development of high-throughput single-cell/single-particle microbeams, which can deliver defined amounts of ionizing radiation into individual cells with a spatial resolution of a few microns or better. The ability of a microbeam to put double strand break damage at any specific known location in a given cell has allowed new approaches to the study of damage signaling.

Proper citation: Radiological Research Accelerator Facility (RRID:SCR_001425) Copy   

•   Source: SciCrunch Registry
  

https://pubmed.ncbi.nlm.nih.gov/21129402/

Source code that allows you to calculate the different measures used in Kreuz T, Chicharro D, Greschner M, Andrzejak RG (2011): Time-resolved and time-scale adaptive measures of spike train synchrony, http://www.sciencedirect.com/science/article/pii/S0165027010006564. Journal of Neuroscience Methods,195, 92-106 & Kreuz T, Chicharro D, Andrzejak RG, Haas JS, and Abarbanel HDI (2009) Measuring multiple spike train synchrony. Journal of Neuroscience Methods 183:287-299 http://www.sciencedirect.com/science/article/pii/S0165027009003616

Proper citation: Time-resolved and time-scale adaptive measures of spike train synchrony (RRID:SCR_001667) Copy   

•   Source: SciCrunch Registry
  

http://www.civm.duhs.duke.edu/

Biomedical technology research center dedicated to the development of novel imaging methods for the basic scientist and the application of the methods to important biomedical questions. The CIVM has played a major role in the development of magnetic resonance microscopy with specialized MR imaging systems capable of imaging at more than 500,000x higher resolution than is common in the clinical domain. The CIVM was the first to demonstrate MR images using hyperpolarized 3He which has been moved from mouse to man with recent clinical trials performed at Duke in collaboration with GE. More recently the CIVM has developed the molecular imaging workbench---a system dedicated to multimodality cardiopulmonary imaging in the rodent. Their collaborators are employing these unique imaging systems in an extraordinary range of mouse and rat models of neurologic disease, cardiopulmonary disease and cancer to illuminate the underlying biology and explore new therapies.

Proper citation: Center for In Vivo Microscopy (RRID:SCR_001426) Copy   

•   Source: SciCrunch Registry
  

http://www.njbiomaterials.org/resbio_main.htm

Biomedical technology research center that works to develop integrated tools and technologies that advance the discovery of polymeric biomaterials for regenerative medicine, the delivery of biological agents, and the next generation of medical implants. To achieve its mission, RESBIO's research is focused on the development of combinatorial and computational approaches to biomaterials design and optimization. Within this framework, RESBIO employs and uses: * Advanced multi-photon confocal laser microscopy to explore, understand, and control the response of cells in contact with artificial surfaces * Electron microscopy techniques to study the effect of nano-scale surface morphological features on cell behavior RESBIO research emphasizes the integration of a strong synthetic effort to create new biomaterial candidates with the development of rapid screening techniques for key material and biological properties relevant to the performance of a biomaterial in a given medical application.

Proper citation: RESBIO (RRID:SCR_001424) Copy   

•   Source: SciCrunch Registry
  

http://www.paintshoppro.com/en/products/paintshop-pro/standard/

Photo-editing software including editing features, fast brushes, creative tools and color selection that will help turn snapshots into beautiful, gallery-worthy images.

Proper citation: PaintShop Pro (RRID:SCR_000338) Copy   

•   Source: SciCrunch Registry
  

https://www.med.upenn.edu/CAMIPM/

Biomedical technology research center dedicated to the development and application of innovative, novel magnetic resonance and optical imaging techniques. The facility's core sections provide research and computing resources for numerous user, collaborative, and training projects. The focus of this resource is on developing instrumentation, methodologies, and data analysis techniques for the quantitative assessment of functional, structural, and metabolic parameters in humans with the use of multinuclear magnetic resonance, novel spectral, perfusion, functional, and optical imaging techniques. These technological developments are driven by collaboration with scientists from within and outside University of Pennsylvania, the primary institution. Specifically, the Resource is focused on the development of quantitative, noninvasive MR and optical imaging based biomarkers for studying tissue metabolism and function, with an eye towards clinical translation through early diagnosis. The Center also provides support in the development and evaluation of new therapies in a variety of diseases.

Proper citation: Center for Magnetic Resonance and Optical Imaging (RRID:SCR_001428) Copy   

•   Source: SciCrunch Registry
  

http://www.government.nl/ministries/ocw

Dutch Ministry responsible for education, culture, science, research, gender equality and communications.This organization also strives to make a good work environment for teachers, artists and researchers.

Proper citation: Dutch Ministry of Education Culture and Science (RRID:SCR_000332) Copy   

•   Source: SciCrunch Registry
  

https://journals.aps.org/pre/abstract/10.1103/PhysRevE.80.026217

Source code that allows you to calculate the different measures used in Chicharro D, Andrzejak RG (2009): Reliable detection of directional couplings using rank statistics. Physical Review E, 80, 026217.

Proper citation: Reliable detection of directional couplings using rank statistics (RRID:SCR_001662) Copy   

•   Source: SciCrunch Registry
  

http://www.labspaces.net/view_blog.php?ID=581

Lady Scientist chronicles the author's journey through grad school and navigating the so-called Two Body Problem. The author, Amanda (at) Lady Scientist, is a recent Ph.D. graduate in biochemistry and molecular biology.

Proper citation: Lady Scientist (RRID:SCR_000567) Copy   

•   Source: SciCrunch Registry