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http://www.einstein.yu.edu/centers/diabetes-translational-research/timc/

Core facility that supports research that addresses the prevention and control of diabetes using a social-ecological approach to address the dynamic interrelations of biological, psychological and social factor at a personal and environmental level.

Proper citation: New York Regional Center for Diabetes Translation Research Translational Intervention Methodology Core (RRID:SCR_015180) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/liver-research/research-cores/cell-culture-and-genetic-engineering-core.aspx

Core that provides Liver Research Center investigators an extensive array of customized viral and non-viral vectors, viral and non-viral vectors for reprogramming somatic cells, generating special non-viral vectors, consultation for study design and, if appropriate, data analysis.

Proper citation: Marion Bessin Liver Research Center Genetic Engineering and Gene Therapy (RRID:SCR_015186) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/research/shared-facilities/cores/64/molecular-biology-and-next-generation-technology/

Core that provides services ranging from classical qPCR and RT-qPCR plus specialized preparation of miRNA and development of targeted genotyping assays.

Proper citation: Molecular Biology and Next Generation Technology (RRID:SCR_015184) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/communication-and-literacy/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility whose services include assisting with outreach and recruitment to various populations, developing strategic community partnerships, and developing materials and methods for effective health education within the community.

Proper citation: Washington University Center for Diabetes Translation Research Health Communication and Health Literacy Core Facility (RRID:SCR_015198) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/clinical

Core that is meant to provide members with biostatistical support and the infrastructure to execute disease-based clinical research. Its services include advising on research designs, including project implementation and data collection methods, guidance on appropriate statistical methods based on study design, training and access to REDCap (Research Electronic Data Capture) for research studies, and reviewing REDCap Data Base Structure.

Proper citation: Cincinnati Digestive Health Center Clinical Component-Data Analysis and Management (RRID:SCR_015200) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/molbiology.aspx

Core that provides services in the utilization of advanced genetics and molecular biological techniques and facilitates the implementation of advances in genomics and molecular biology to IBD research. It provides access to capital or resource-intensive methodologies, such as laboratory automation cDNA and siRNA libraries, and BAC-centered recombinant DNA techniques.

Proper citation: Center for the Study of Inflammatory Bowel Disease Genetics Genomics and Molecular Biology Core (RRID:SCR_015201) Copy   

•   Source: SciCrunch Registry

http://clinicaltrials.gov/show/NCT00143949

Randomized, multicenter, double-blind study to determine if renin angiotensin medications, either losartan (angiotensin II blocker) or enalapril (converting enzyme inhibitor), can prevent or delay the onset of diabetic kidney disease in patients with type 1 diabetic patients who do not have hypertension, diabetic nephropathy, or predictive levels of microalbuminuria. Two hundred eight five patients ages 16-61 with 2-20 yrs of Type 1 Diabetes Mellitus and no renal functional abnormalities were randomized into a parallel, double-blind, placebo-controlled study involving 3 groups (95 patients/group). Each group received an angiotensin-converting enzyme inhibitor (ACEI) (enalapril), or an angiotensin II receptor blocker (Losartan), or placebo. All patients had their usual Diabetes Mellitus (DM) management. Baseline studies included measures of glomerular filtration rate (GFR), urinary albumin excretion rate (UAE), blood pressure (BP), and a percutaneous renal biopsy. Patients were followed by quarterly measures of BP, HbA1C, UAE, and drug compliance. There were annual measures of GFR and a repeat renal biopsy after 5 yrs in the study. The main endpoint is kidney structural changes over time, especially mesangial fractional volume (v(Mes/glom)). Secondary endpoints will be other DN structural measures and measures of kidney function (UAE, GFR). These studies will determine whether rennin angiotensin system blockage in the early stages of DN can prevent the early kidney structural changes in this important disorder. Ancillary studies will evaluate the effects of treatment group on the development and progression of diabetic retinopathy and will develop predictors of study participants'''' compliance. Baseline, 2.5 and 5 year retinal fundus photographs in the RASS patients were obtained.

Proper citation: Renin Angiotensin System Study (RRID:SCR_013385) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/policy-and-systems-science-analysis/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility whose services include policy consultation and research design advice, workshops on systems science analysis, and management of a resource library of policy and system science tools and datasets.

Proper citation: Washington University Center for Diabetes Translation Research Policy and Systems Science Analysis in Diabetes Research Core (RRID:SCR_015203) Copy   

•   Source: SciCrunch Registry

http://chicagodiabetesresearch.org/cores/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provide support for diabetes translation research aiming to reduce health disparities and support translation research in the community.

Proper citation: Chicago Center for Diabetes Translation Research Health Disparities and Community-Based Participatory Research Core (RRID:SCR_015178) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10414/collection_id/2234/community_id/1136

Core facility whose goal is to encourage and facilitate effective diabetes translation research among vulnerable minority populations, especially African and Hispanic Americans. They have three sub-units which include the Community-Based Participatory Research Unit/Planning Unit, the Behavioral Intervention Unit, and the Assessment, Design, and Analysis Unit. Services include a variety of assessments (psychological, dietary, community health surveys, physical activity) as well as research and implementation.

Proper citation: Vanderbilt Center for Diabetes Translation Research Community Outreach and Heath Disparities Core (RRID:SCR_015175) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10409/collection_id/2234/community_id/1136

Core facility which offers services such as consultation of study design for community-based research, development of IRB protocols, usage of community resources for recruitment efforts, and access to community charcateristics data and geographic information on the community.

Proper citation: Vanderbilt Center for Diabetes Translation Research Community Engagement Core (RRID:SCR_015173) Copy   

•   Source: SciCrunch Registry

http://derc.yale.edu/cores/transgenic.aspx

Core facility which provides genetically modified mice and rodents, mainly transgenic and knockout mice and rodents in the NOD system. It also provides transgenic mice in F2 (usually B6/C3H) and rats on Sprague-Dawley, and chimeric mice using the 129 strain ES cells. It also provides training and management

Proper citation: Yale Diabetes Research Center Molecular Genetics Core (RRID:SCR_015145) Copy   

•   Source: SciCrunch Registry

http://www.ucdenver.edu/academics/colleges/PublicHealth/research/centers/CAIANH/cdtr/Pages/Administrative-Core.aspx

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 30,2025. Administrative Core of the Center for American Indian and Alaska Native Diabetes Translational Research. The CAIANDTR is dedicated to extending prevention and management research of proven efficacy to both clinical and community settings, with the goal of improving the diabetes-related health of Native Americans.

Proper citation: Center for American Indian and Alaska Native Diabetes Translational Research Administrative Core (RRID:SCR_015148) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/metacore.html

Core which aims to develop and validate metabolomic methods and data analysis software and provide high quality routine metabolomic services. Its services include quantitation of selected water-soluble metabolites, fatty acids, and lipids, quantitation of metabolic fluxes using stable isotope tracers, and identification of novel metabolites involved in diabetes pathophysoiology.

Proper citation: Penn Diabetes Research Center Metabolomics Core (RRID:SCR_015122) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/shp/drc/interventions-translational-core-links

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides expertise and services that range from methods of intervention development, basic study design and data analysis, and cutting-edge methodologies in measurement, to subject recruitment and retention strategies with an emphasis on increasing minority participation.

Proper citation: University of Alabama at Birmingham Diabetes Research Center Interventions and Translation Core (RRID:SCR_015135) Copy   

•   Source: SciCrunch Registry

http://www.cure.med.ucla.edu/cores/animal-models

Core that provides in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of gastrointestinal (GI) function and brain-gut interactions in rodents to members and associate members of the CURE: DDRCC.

Proper citation: CURE - Digestive Diseases Research Center Animal Models Core (RRID:SCR_015217) Copy   

•   Source: SciCrunch Registry

http://cihd.cores.utah.edu/administration/

Core facility which oversees the operational and financial functioning of the CIHD. It aims include periodically reviewing current membership and selecting new members, monitoring administrative and scientific activities of the CIHD, and selecting projects to be funded through the Pilot and Feasibility Program.

Proper citation: Center for Iron and Heme Disorders at the University of Utah Administrative Core (RRID:SCR_015338) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/administrative

Core that provides governance, financial and operational management, and strategic planning functions for the DDC. This core is also responsible for coordinating the annual Pilot Feasibility Awards program, as well as the weekly GI Research Forum and the annual Frontiers in Digestive Medicine Symposium.

Proper citation: Texas Medical Center Digestive Diseases Center Administrative Core (RRID:SCR_015222) Copy   

•   Source: SciCrunch Registry

https://ww2.mc.vanderbilt.edu/DDRC/6916

Core that aims to further digestive disease research by providing services including identification of oxidized lipids by GC/MS and HR-LC/MS, proteomics for identification and characterization of proteins by MudPIT and LC-MS/MS techniques, quantification of protein expression by LC-MS/MS, interpretation and analysis of mass spectrometry data, and quantification of trace elements in physiologic fluids by ICP-MS.

Proper citation: Vanderbilt Digestive Disease Research Center Bioanalytical Mass Spectrometry and Proteomics Core (RRID:SCR_015223) Copy   

•   Source: SciCrunch Registry

http://chicagodiabetesresearch.org/cores/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provides support to investigators in designing and carrying out translational studies assessing outcomes for patients with diabetes, or populations at risk.

Proper citation: Chicago Center for Diabetes Translation Research Outcomes Improvement Core (RRID:SCR_015221) Copy   

•   Source: SciCrunch Registry