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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://qualimap.bioinfo.cipf.es/
Software application written in Java and R that provides both a Graphical User Inteface (GUI) and a command-line interface to facilitate the quality control of alignment sequencing data. It examines sequencing alignment data in SAM / BAM files according to the features of the mapped reads and provides an overall view of the data that helps to the detect biases in the sequencing and/or mapping of the data and eases decision-making for further analysis.
Proper citation: QualiMap (RRID:SCR_001209) Copy
http://www.omixon.com/data-analysis-and-pro/
Software application suite to help clinical labs adopt next generation sequencing for the analysis of diagnostic gene targets.
Proper citation: Omixon Target Data Analysis (RRID:SCR_001207) Copy
http://purl.bioontology.org/ontology/ICD11-BODYSYSTEM
Ontology of a set of body-system terms used in the ICD (International Classification of Diseases) 11 revision
Proper citation: Body System Terms from ICD11 (RRID:SCR_001252) Copy
http://www.bioconductor.org/packages/release/bioc/html/CGEN.html
Software R package for analysis of case-control studies in genetic epidemiology.
Proper citation: CGEN (RRID:SCR_001251) Copy
http://www.softgenetics.com/mutationSurveyor.php
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software for DNA sequencing analysis that integates with Sanger Sequencing files generated by Applied Biosystems Genetic Analyzers, MegaBACE, and Beckman CEQ electrophoresis systems. It can be used to find single nucleotide polymorphisms (SNPs), insertions and deletions (INDELS), and somatic mutations in direct sequencing, PCR sequencing, mitochondrial DNA sequencing, and resequencing projects.
Proper citation: Mutation Surveyor (RRID:SCR_001247) Copy
http://www.bioconductor.org/packages/release/bioc/html/genoset.html
Software package to load, manipulate, and plot copynumber and BAF data by providing classes similar to ExpressionSet for copy number analysis. The class extends ExpressionSet by adding a locData slot for a RangedData or GRanegs object. This object contains feature genome location data and provides for efficient subsetting on genome location. CNSet and BAFSet extend GenoSet and require assayData matrices for Copy Number (cn) or Log-R Ratio (lrr) and B-Allele Frequency (baf) data. Implements and provides convenience functions for processing of copy number and B-Allele Frequency data.
Proper citation: GenoSet (RRID:SCR_001275) Copy
https://www.benaroyaresearch.org/
Non-profit organization based out of Seattle, Washington that conducts medical research on autoimmune disease.
Proper citation: Benaroya Research Institute (RRID:SCR_001272) Copy
http://www.bioconductor.org/packages/2.14/bioc/html/CGHbase.html
Software package that contains functions and classes that are needed by arrayCGH packages.
Proper citation: CGHbase (RRID:SCR_001279) Copy
http://bioconductor.org/packages/release/bioc/html/quantsmooth.html
Software package for quantile smoothing and genomic visualization of array data.
Proper citation: quantsmooth (RRID:SCR_001271) Copy
http://sourceforge.net/projects/mutascope/
Software suite to analyze data from high throughput sequencing of PCR amplicons, with an emphasis on normal-tumor comparison for the accurate and sensitive identification of low prevalence mutations.
Proper citation: Mutascope (RRID:SCR_001265) Copy
A Swiss global health-care company that operates under two divisions: Pharmaceuticals and Diagnostics.
Proper citation: Roche (RRID:SCR_001326) Copy
Biomedical technology research center that creates optimal facilities and environments and support for macromolecular structure determination by synchrotron X-ray diffraction at the National Synchrotron Light Source for the benefit of outside and in-house investigators. The PXRR innovates new access modes such as Mail-in crystallography, builds new facilities, currently on the X25 undulator, advances automation, develops remote participation software, collaborates with outside groups, teaches novice users, and supports vising investigators with 7-day, 20-hours staff coverage.
Proper citation: Macromolecular Crystallography Research Resource (RRID:SCR_001442) Copy
https://medicine.yale.edu/keck/nida/yped/
Open source system for storage, retrieval, and integrated analysis of large amounts of data from high throughput proteomic technologies. YPED currently handles LCMS, MudPIT, ICAT, iTRAQ, SILAC, 2D Gel and DIGE. The repository contains data sets which have been released for public viewing and downloading by the responsible Primary Investigators. It includes proteomic data generated by the Yale NIDA Neuroproteomics Center (http://medicine.yale.edu/keck/nida/index.aspx). Sample descriptions are compatible with the evolving MIAPE standards.
Proper citation: YPED (RRID:SCR_001436) Copy
http://www.anxietyaustralia.com.au/
Anxiety Treatment Australia provides information about anxiety disorders, the treatment options, psychologists around Australia who treat anxiety disorders, group therapy & workshops, support groups, articles, resources and links to other sites. Sponsors: his website is brought to you by Catherine Madigan, a Melbourne Clinical Psychologist who specializes in the treatment of Anxiety Disorders (ABN 51 109 368 630).
Proper citation: Anxiety Treatment Australia: Anxiety Disorder Help, Information and Psychologist List (RRID:SCR_001434) Copy
http://www.nitrc.org/projects/philips_users/
Communnity project to help support the efforts of investigators using Philips Healthcare systems. This clearingsite helps users find forums, mailinglists, etc. that support this community. If you have suggestions for inclusion, let the project admin know!
Proper citation: Philips Users Community (RRID:SCR_001438) Copy
http://www.morpholinodatabase.org/
Central database to house data on morpholino screens currently containing over 700 morpholinos including control and multiple morpholinos against the same target. A publicly accessible sequence-based search opens this database for morpholinos against a particular target for the zebrafish community. Morpholino Screens: They set out to identify all cotranslationally translocated genes in the zebrafish genome (Secretome/CTT-ome). Morpholinos were designed against putative secreted/CTT targets and injected into 1-4 cell stage zebrafish embryos. The embryos were observed over a 5 day period for defects in several different systems. The first screen examined 184 gene targets of which 26 demonstrated defects of interest (Pickart et al. 2006). A collaboration with the Verfaillie laboratory examined the knockdown of targets identified in a comparative microarray analysis of hematopoietic stem cells demonstrating how microarray and morpholino technologies can be used in conjunction to enrich for defects in specific developmental processes. Currently, many collaborations are underway to identify genes involved in morphological, kidney, skin, eye, pigment, vascular and hematopoietic development, lipid metabolism and more. The screen types referred to in the search functions are the specific areas of development that were examined during the various screens, which include behavior, general morphology, pigmentation, toxicity, Pax2 expression, and development of the craniofacial structures, eyes, kidneys, pituitary, and skin. Only data pertaining to specific tests performed are presented. Due to the complexity of this international collaboration and time constraints, not all morpholinos were subjected to all screen types. They are currently expanding public access to the database. In the future we will provide: * Mortality curves and dose range for each morpholino * Preliminary data regarding the effectiveness of each morpholino * Expanded annotation for each morpholino * External linkage of our morpholino sequences to ZFIN and Ensembl. To submit morpholino-knockdown results to MODB please contact the administrator for a user name and password.
Proper citation: Morpholino Database (RRID:SCR_001378) Copy
http://neuro.imm.dtu.dk/wiki/Main_Page
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 10, 2025. Semantic wiki with structured information, primarily from functional and molecular neuroimaging papers, but there are also other types of papers, e.g., from personality genetics. It lists results from neuroimaging studies, such as Talairach coordinates and brain volume measurements, as well as software packages and brain regions. SQL dumps of the structured information in the wiki is available so complex queries can be formed. The Brede Wiki templates store the structured information from neuroscience papers and editors may add free format text. Template definitions format the data so it is presented as tables on the formatted wiki-page. From a given PMID a web-service can format information from PubMed for inclusion in the Brede Wiki. A Matlab script can extract coordinates from SPM5 and format them in the Talairach coordinate template format.
Proper citation: Brede Wiki (RRID:SCR_001411) Copy
http://www.g-node.org/projects/odml
Mark up language for collecting and exchanging metadata in an automated, computer-based fashion, developed for neuroscience, specifically, neurophysiology experiments. In odML arbitrary metadata information is stored as extended key-value pairs in a hierarchical structure. Central to odML is a clear separation of format and content, i.e., neither keys nor values are defined by the format. This makes odML flexible enough for storing all available metadata instantly without the necessity to submit new keys to an ontology or controlled terminology. Common standard keys can be defined in odML-terminologies for guaranteeing interoperability.
Proper citation: Open metadata mark up language (RRID:SCR_001376) Copy
http://scitools.idtdna.com/analyzer/Applications/OligoAnalyzer/
Web-based application for analyzing oligonucleotides. Analysis proceeds after the sequence has been entered and the calculations modified based on target type, oligo concentration, sodium ion concentration, magnesium ion concentration, and dNTP concentration.
Proper citation: Integrated DNA Technologies OligoAnalyzer (RRID:SCR_001363) Copy
Software package for nucleic acid folding and hybridization prediction. It has capabilities to predict folding for single-stranded RNA or DNA through a combination of free energy minimization, partition function calculations and stochastic sampling. The program runs on Unix and Linux platforms as well as Mac OS X and Windows.
Proper citation: UNAFold (RRID:SCR_001360) Copy
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