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http://www.scienceexchange.com/facilities/microarray-and-bioinformatics-core-mmc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Core facility that provides the following services: RNA quality analysis service, qRT-PCR service, Microarray service, Bioinformatics data analysis service. The Core provides state of the art training, instrumentation, services and bioinformatics-driven data analysis to the Meharry Community in microarray experimental design, manipulation, and gene expression analysis. They also aid investigators and trainees in validation of microarray results using RNA QA/QC and real time PCR results. Finally, this Core Resource aids Meharry investigators and trainees with high performance computation in proteomics as well as genomics. Gene and protein pathways analysis and shotgun proteomics (mass spectrometry) analysis are just two more of the services that we provide. It is their aim to keep this facility up to date computationally and intellectually with state of the art Omics services to support education and research in microarray, genomics and proteomics data analysis, computational biology, and systems biology.

Proper citation: Meharry Microarray and Bioinformatics Core (RRID:SCR_012229) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/anti-infectives-screening-and-insectary-core-facilities-nyu

Our insectary produces five rodent malaria strains weekly and will ship live sporozoite infected Anopheles stephensi to investigators for research use (Plasmodium berghei GFP, luciferase or red-star and P. yoelii-GFP) Anti-infective testing including in vitro EC50, in vivo mice infection are available against for major parasitic diseases: Malaria, Leishmaniasis, Chagas and African Trypanosomiasis.

Proper citation: NYU Anti-Infectives Screening and Insectary Core Facilities (RRID:SCR_012350) Copy   

•   Source: SciCrunch Registry

https://dna.dbi.udel.edu/

Provides genomics and molecular biology services for University of Delaware research groups and outside users.Supports genomic research through established expertise with genomics technologies.

Proper citation: University of Delaware Sequencing and Genotyping Center Core Facility (RRID:SCR_012230) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/proteomics/index.php

Provides LCMS/MS analysis of proteins in clinical, environmental and other biological samples. As a shared facility of the Bindley Bioscience Center (BBC) in Discovery Park of Purdue University, the facility enables both targeted and global analysis of proteins, their post-translational modifications and analysis of protein complexes and protein-protein interactions. Coupled with different chromatographic separation techniques, modern mass spectrometric instrumentation, and advanced scientific and bioinformatics expertise, the facility provides unique opportunities for researchers at Purdue and beyond to perform quantitative analysis of proteins in complex biological samples using both global, as well as, targeted proteomic approaches.

Proper citation: Purdue University Proteomics Core Facility (RRID:SCR_012351) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/pharmacology/index.php

Purdue Translational Pharmacology (PTP) facility provides in vivo pharmacological evaluation using porcine models. The facility is situated in the Purdue University School of Veterinary Medicine complex, which provides constant care and monitoring of the animals. The PTP uses unique penning systems to automate blood sampling and maintain a humane and stress free environment for test subjects. The PTP synergizes with the Metabolite Profiling Facility in the Bindley Bioscience Center, which facilitates the pharmacological analysis of blood samples collected.

Proper citation: Purdue Translational Pharmacology Core Facility (RRID:SCR_012354) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-cell-separation-facility-purdue

The Bindley Bioscience Flow Cytometry and Cell Separation Facility provides advanced cell and particle analysis and sorting using flow cytometry based technology. The facility also provides training in flow cytometry analysis and sorting techniques. The facility also provides expert consultation for assay and protocol development for flow cytometry analysis and cell separation.

Proper citation: Bindley Bioscience Flow Cytometry and Cell Separation Facility (RRID:SCR_012353) Copy   

•   Source: SciCrunch Registry

http://gccri.uthscsa.edu/genome_sequencing.html

Core performs all protocols necessary for preparing a sample to be sequenced on the Illumina HiSeq2000 system. Core is also a research group with experience in customizing experiments and developing new applications. Core provides: Complete project consultation for optimal experimental design and setup, Super saver pricing for entire UT Health Science Center research community, especially research focusing on cancer genomics, Complete quality control analysis during library preparation and data generation, Secure website to download the sequencing data with quality information, Full project report, Bioinformatics analysis option available, NCBI GenBank submission option available

Proper citation: University of Texas Health Science Center at San Antonio Genome Sequencing Facility (RRID:SCR_012237) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genomics-core

The mission of the Genomics Core is to provide state-of-the-art genomic services including genotyping and cell banking to investigators from UTHSCSA, CTRC and the local scientific community in an economical and timely manner.

Proper citation: UTHSCSA Genomics Core (RRID:SCR_012239) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/x-ray-crystallography-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15, 2024. The mission of the X-ray Crystallography Core Laboratory is to provide state-of-the-art resources to researchers at the University of Texas Health Science Center at San Antonio, and to external users, enabling the detailed 3-D analyses of biological macromolecules that play important roles in human health. This is a full service core in that it not only offers access to sophisticated equipment and technologies but also offers advice and technical assistance in sample preparation. Services are also provided to investigators without funding to facilitate the development of pilot data for new potentially fundable projects, as core resources permit. If priority of usage becomes an issue, this will be decided by the Core Director in consultation with the other principal scientists based on the feasibility of the projects, their scientific merits and their relevance to human health.

Proper citation: UTHSCSA X-ray Crystallography Core Laboratory (RRID:SCR_012242) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/microct-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22, 2024. UTHSCSA Orthopaedics Bone and Mineral High-Resolution 3D Imaging Facility is a NIH-funded imaging facility equipped with two ex-vivo desktop microCT systems, a reference point indenter and a furnace. The non-destructive nature of microCT imaging allows the researcher to strengthen his/her research by using the same sample for histology or biomechanical testing after microCT imaging. Advantages of Micro-CT - Micro-CT allows for extremely high-resolution, non-destructive, 3D imaging. - No staining, sectioning, or sample preparation needed - Samples can be frozen or fixed - Since Micro-CT is non-destructive, other assays may be carried out after, thereby increasing the amount of data per sample - Data acquisition is a rapid process, allowing for a speedy return of samples

Proper citation: UTHSCSA MicroCT Core Laboratory (RRID:SCR_012241) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/diygenomics

DIYgenomics provides crowdsourced health research study protocol design and operation in pre-clinical and disease cohorts. Founded in 2010, the mission of DIYgenomics is the realization of preventive medicine through the integrated study of multiple health data streams. The generalized hypothesis for DIYgenomics studies is that one or more genetic polymorphisms (mutations) may result in out-of-bounds phenotypic biomarker conditions (for example, low Vitamin B blood levels), that may be ameliorated through personalized intervention.

Proper citation: DIYgenomics (RRID:SCR_012243) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/marvell-nanofabrication-laboratory, micro/nanoelectromechanical systems, microelectronics

The Marvell Nanofabrication Laboratory at the University of California, Berkeley is a multidisciplinary facility that serves research and education in the areas of integrated circuits (ICs) and systems, micro/nanofabrication technologies, micro/nanoelectromechanical (MEMS/NEMS) systems, advanced materials and interdisciplinary applications of microelectronics. This facility offers processing for both 4 inch and 6 inch substrates (wafers).

Proper citation: UC Berkeley Marvell Nanofabrication Laboratory (RRID:SCR_012246) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/metabolomics-core-laboratory-mass-spectrometry-uthscsa

Cutting-edge mass spectrometers deliver extremely high mass accuracy and resolution to elucidate the identity and quantity of small molecules. Metabolomics Laboratory Services: Qualitative and quantitative analysis of small molecules - Molecular mass determination - Structural elucidation - Quantification Targeted and discovery modes of analysis - Quantitative analysis of targeted metabolites - Metabolite profiling for differential comparisons between experimental groups - High-throughput sample analysis The Metabolomics Laboratory is supported by awards from the National Institutes of Health, including a Shared Instrumentation grant (1S10RR031586-01) and a supplement to the Clinical and Translational Sciences Award (3UL1RR025767-03S1).

Proper citation: UTHSCSA Metabolomics Core Laboratory Mass Spectrometry (RRID:SCR_012245) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cell-imaging-centre

The Cell Imaging Centre is primarily equipped to benefit research scientists within the faculty of medicine and dentistry at the University of Alberta, and is also available to accommodate users from other academic institutes and commercial companies.

Proper citation: UAlberta Cell Imaging Centre (RRID:SCR_012325) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/martinos-center-for-biomedical-imaging-core-facility-harvard

Core facility that provides the following services: Positron emission tomography service.

The Martinos Center''''s dual mission includes translational research and technology development. The core technologies being developed and used at the center are magnetic resonance imaging (MRI) and spectroscopy (MRS), magnetoencephalography (MEG) and electroencephalograpy (EEG), near infra-red spectroscopy (NIRS) and diffuse optical tomography (DOT), Positron Emission Tomography (PET), electrophysiology, molecular imaging, and computational image analysis. A particular area of innovation at the Center is Multimodal Functional Neuroimaging which involves the integration of imaging technologies. They are also world leaders in the development of primate neuroimaging techniques. Major areas of research at the center include, psychiatric, neurologic and neurovascular disorders, basic and cognitive neuroscience, cardiovascular disease, cancer and more. With an extensive and expanding inventory of state-of-the-art imaging facilities, a world class team of investigators and collaborators, and important government, industry and private supporters, the Martinos Center is leading the way to new advances and applications in biomedical imaging.

Proper citation: MGH Martinos Center for Biomedical Imaging Core Facility (RRID:SCR_012324) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/immunogenetics-center-ucla

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960''''s. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. In the intervening years, laboratory and scientific personnel, from the US and abroad, have learned HLA typing through courses and workshops at the UCLA Immunogenetics laboratory. The center provides immunogenetics and histocompatibility testing services to a wide range of physicians, patients, pharmaceutical companies and other medical facilities. The laboratory is a World Health Organization reference laboratory for HLA, and is licensed by the State of California, New York, Maryland, Pennsylvania and Rhode Island, is CMS certified and accredited by the American Society for Histocompatibility and Immunogenetics.

Proper citation: UCLA Immunogenetics Center (RRID:SCR_012206) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/high-throughput-clinical-proteomics-core-ucla

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016. The High-Throughput Clinical Proteomics (HTCP) core laboratory is a mass spectrometry core facility designed to profile large numbers of clinical samples for changes in protein content. We use small amounts (micrograms) of protein from samples such as urine, plasma, CSF, and cell lysates and incubate them with magnetic beads that bind different subsets of the total proteome. We then examine the different subsets of small proteins and peptides by high-resolution MALDI-TOF mass spectrometry. We measure the amounts and intact masses of the proteins in the samples and determine which have the greatest statistical relevance in defining clinical groupings before moving to physically isolate those peptides/proteins and identify them. The method works best for peptides and small proteins below 25 kDa and is an excellent complement to gel-based methods such as DIGE.

Proper citation: UCLA High-Throughput Clinical Proteomics Core (RRID:SCR_012205) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bioinformatics-support-unit

Core provides support to life science researchers with data analysis and experimental design from sequence analysis, microarrays, proteomics and beyond.

Proper citation: Newcastle University Bioinformatics Support Unit (RRID:SCR_012297) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/therapeutic-validation-core-iu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Therapeutic Validation core (TVC) assists clinical investigators to develop and perform correlative biological assays needed to validate mechanism(s) of action of candidate drugs/therapies and to develop and test new hypotheses. The TVC also provides technical and intellectual support in the development, implementation, and validation of predictive and pharmacodynamic biomarkers for novel, molecularly-targeted anticancer agents.

Proper citation: IUSM Therapeutic Validation Core (RRID:SCR_012211) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-core-facility-utah

Serving 120+ investigators with a 5 laser high speed sorter and 3 benchtop analyzers with 13+ color capabilities, the Utah Flow Cytometry Core Facility has developed a paradigm to balance productivity with quality to minimize the cost per research project, keep overall costs contained, and provide the necessary scientific support. Central to this paradigm is a close working relationship with investigators to define their projects in the early stages of development to make optimal and efficient use of flow cytometry. In addition to high quality and well maintained instrumentation, success of this approach requires focused efforts in three major areas: 1) education of ALL users (faculty and staff) in the science and technology of flow cytometry, 2) active involvement in the scientific development of the project, 3) continuing education for core staff.

Proper citation: University of Utah Flow Cytometry Core Facility (RRID:SCR_012210) Copy   

•   Source: SciCrunch Registry