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http://www.cnbc.cmu.edu/

CNBC is joint venture of University of Pittsburgh and Carnegie Mellon University. Our center leverages the strengths of the University of Pittsburgh in basic and clinical neuroscience and those of Carnegie Mellon in cognitive and computational neuroscience to support a coordinated cross-university research and educational program of international stature. In addition to our Ph.D. program in Neural Computation, we sponsor a graduate certificate program in cooperation with a wide variety of affiliated Ph.D. programs.

Proper citation: Center for the Neural Basis of Cognition (RRID:SCR_002301) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/biobank

Provides access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research. Services include biospecimen storage, serum and plasma processing, preparation of kits for sample collection and shipping, automated DNA/RNA extraction from blood, saliva, tissue and other materials, biofluid collection, processing and storage, tissue collection, processing and storage.Home to Better Outcomes for Children (BofC) biorepository.

Proper citation: Cincinnati Biobank Core Facility (RRID:SCR_004281) Copy   

•   Source: SciCrunch Registry

http://www.radiology.ucsf.edu/cind

Biomedical technology research center that develops and validates new imaging methods for detecting brain abnormalities in neurodegenerative diseases, including Alzheimer's disease, vascular dementia, frontotemporal dementia, Parkinson's disease, as well as epilepsy, depression, and other conditions associated with nerve loss in the brain. As people around the globe live longer, the impact of neurodegenerative diseases is expected to increase further with dire social and economical consequences for societies if no effective treatments are developed soon. The development at CIND is aimed to improve magnetic resonance imaging (MRI). The ultimate goal of the scientific program is to identify imaging markers that improve accuracy in diagnosing neurodegenerative diseases at early stages, achieve more reliable prognoses of disease progression, and facilitate the discovery of effective treatment interventions. In addition to addressing the general needs for studying neurodegenerative diseases, another focus of CIND concerns brain diseases associated with military service and war combat, such as post traumatic stress disorder (PTSD), brain trauma, gulf war illness and the long-term effects of these conditions on the mental health of veterans. The symbiosis between CIND and the Veterans Administration Medical Center in San Francisco makes this program uniquely suited to serve military veterans.

Proper citation: Center for Imaging of Neurodegenerative Diseases (RRID:SCR_001968) Copy   

•   Source: SciCrunch Registry

http://www.duke.edu/web/gpcr-assay/index.html

Describes data from and access to permanent cell lines containing beta-arrestin fluorescent protein biosensors. This assay Bank provides plasmids, cells lines, and resulting data to the NIDA/NIH funded research community in order to better understand and combat addiction.

Proper citation: Addiction Research GPCR Assay Bank (RRID:SCR_002895) Copy   

•   Source: SciCrunch Registry

http://icr.coh.org/

Group of 10 academic laboratories provide pancreatic islets of cGMP-quality to eligible investigators for use in FDA approved, IRB-approved transplantation protocols in which isolated human islets are transplanted into qualified patients afflicted with type 1 diabetes mellitus; optimize the harvest, purification, function, storage, and shipment of islets while developing tests that characterize the quality and predict the effectiveness of islets transplanted into patients with diabetes mellitus; and provide pancreatic islets for basic science studies. The centers are electronically linked through an Administrative and Bioinformatics Coordinating Center (ABCC). The ABCC manages a system with objectively defined criteria that establishes the order of priority for islet distribution. It also provides database and other informatics to track the utilization of pancreata and all distributed clinical grade islets for transplant and basic research, and supports the Islet Cell Resource Centers Consortium so that the research community has a single entry point to the program. Qualified researchers from domestic institutions may request islets by submitting a written application to the director of the ABCC. The ICRs will distribute Islets as appropriate for either clinical or basic science protocol use to eligible investigators who have received a favorable review and subsequent approval by the ICR Steering Committee (SC). The Administrative and Bioinformatics Coordinating Center (ABCC) manages the distribution according to a priority list. The ABCC will give preference to investigators who have peer-reviewed, NIH-funded research support.

Proper citation: Islet Cell Resource Centers (RRID:SCR_002806) Copy   

•   Source: SciCrunch Registry

http://www.ccmg-ccgm.org/

National voluntary specialty organization that serves its members, governments and public by Certifying individuals who provide medical genetics services, Establishing professional and ethical standards of medical genetics services, Establishing standards of medical genetics training, Providing professional and public education, Informing public policy.

Proper citation: Canadian College of Medical Geneticists (RRID:SCR_003013) Copy   

•   Source: SciCrunch Registry

http://www.immunospot.com

A Commercial tissue bank

Proper citation: Cellular Technology Ltd Cryopreserved PBMC (RRID:SCR_004346) Copy   

•   Source: SciCrunch Registry

http://ccr.coriell.org/Sections/Collections/CHDI/?SsId=45

HD Community BioRepository is a secure, centralized repository that stores and distributes quality-controlled, reliable research reagents. This repository currently provides access to huntingtin DNAs, polyclonal antibodies (with antigenic peptides) and cell lines. Monoclonal antibodies and hybridomas will be added in the near future. Working together with the Coriell Institute for Medical Research, CHDI Foundation established this secure, centralized repository to store and distribute quality-controlled and reliable research reagents to give research scientists unobstructed access to biomaterials and to support the discovery of therapeutics that will slow or prevent Huntington's disease. Huntington's disease is a fatal, familial disease caused by a mutation in the huntingtin gene. The mutation causes brain cells to malfunction, resulting in cognitive and physical impairments that, over the course of the disease, isolate and constrain the individual. There is currently no way to stop or reverse the course of Huntington's disease. Researchers currently not collaborating with CHDI Foundation may request these Huntington's disease resources from the HD Community BioRepository through the website; CHDI collaborators are asked to contact Mithra Mahmoudi at CHDI Management. Materials will be sent after completing a simple online MTA. Recipients are asked to cover the costs of shipping and handling. Persons with Huntington's disease bioresources interested in making them available to the research community through the HD Community BioRepository should also contact CHDI Management.

Proper citation: HD Community BioRepository (RRID:SCR_004621) Copy   

•   Source: SciCrunch Registry

http://www.ilc.cnr.it/indexflash.html

ILC-CNR has been one of the major promoters of the notion of language resources as the central component of the linguistic infrastructure (aware also of its cultural, economical and political implications), has coordinated the major initiatives relating to language resources and standardization and has often been the promoter of new paradigms in the field. ILC-CNR has coordinated numerous international, European and national strategic initiatives and projects. ILC-CNR has designed and built several types of corpora and lexicons and the respective ontologies, has developed a complete chain of tools for a robust processing of the Italian language, for the acquisition of information from corpora and for word-sense disambiguation and has developed technologies for several application domains (question answering, information retrieval, text mining, monolingual and multilingual terminology extraction, ontology acquisition and structuring, summarisation, filtering of Web documents, preservation of the cultural heritage through digital image processing and digital libraries techniques etc.). The research fields of the Institute are: Models and methods for natural language processing, and mono- and multilingual application prototypes. Design of international standards and development of computational language resources. Design and implementation of architectures and infrastructures for language resources and language technologies. Computational methods and tools for humanistic research, particularly in linguistic, literary, and philological disciplines, and in lexicography.

Proper citation: Institute of Computational Linguistics (RRID:SCR_004501) Copy   

•   Source: SciCrunch Registry

http://neuroscience.berkeley.edu/

Portal for UC Berkeley's neuroscience research center. The group focuses on interdisciplinary collaboration between neuroscientists and members of UC Berkeley programs in engineering, chemistry, statistics, and computation. It also runs the neuroscience PhD program.

Proper citation: Helen Wills Neuroscience Institute (RRID:SCR_001991) Copy   

•   Source: SciCrunch Registry

http://ccr.coriell.org/Sections/Collections/IPBIR/?SsId=18

The purpose of the IPBIR - Integrated Primate Biomaterials and Information Resource is to assemble, characterize, and distribute high-quality DNA samples of known provenance with accompanying demographic, geographic, and behavioral information in order to stimulate and facilitate research in primate genetic diversity and evolution, comparative genomics, and population genetics. Further research in these areas will advance our understanding of human origins, the biological basis of cognitive processes, evolutionary history and relationships, and social structure, and will provide critical scientific information needed to facilitate conservation of biological diversity. The derived DNA will be openly available to the broad scientific community who agree to restrict use to non-commercial purposes. DNA and cell culture samples are distributed only to qualified professional persons who are associated with recognized research, medical, or educational organizations engaged in research.

Proper citation: IPBIR - Integrated Primate Biomaterials and Information Resource (RRID:SCR_004614) Copy   

•   Source: SciCrunch Registry

https://catalog.coriell.org/

A biorepository and biomaterial supply resource which establishes, verifies, maintains, and distributes cells, cultures and DNA derived from cell cultures to the scientific community around the world. Scientists can browse the sample catalog and request specific cell lines for their research studies. An inventory of the remaining stock of each cell line and DNA preparation is presented in real time. Coriell's significant cell biobank collections include: NIGMS Human Genetic Cell Repository, NINDS Human Genetics DNA and Cell Line Repository, NIA Aging Cell Repository, NHGRI Sample Repository for Human Genetic Research, NEI Age-Related Eye Disease Study (AREDS) Genetic Repository, HD Community BioRepository, American Diabetes Association, GENNID Study, and Autism Research Resource. The repositories are ISO 9000-2001 compliant.

Proper citation: Coriell Cell Repositories (RRID:SCR_003244) Copy   

•   Source: SciCrunch Registry

http://neuromab.ucdavis.edu/

A national mouse monoclonal antibody generating resource for biochemical and immunohistochemical applications in mammalian brain. NeuroMabs are generated from mice immunized with synthetic and recombinant immunogens corresponding to components of the neuronal proteome as predicted from genomic and other large-scale cloning efforts. Comprehensive biochemical and immunohistochemical analyses of human, primate and non-primate mammalian brain are incorporated into the initial NeuroMab screening procedure. This yields a subset of mouse mAbs that are optimized for use in brain (i.e. NeuroMabs): for immunocytochemical-based imaging studies of protein localization in adult, developing and pathological brain samples, for biochemical analyses of subunit composition and post-translational modifications of native brain proteins, and for proteomic analyses of native brain protein networks. The NeuroMab facility was initially funded with a five-year U24 cooperative grant from NINDS and NIMH. The initial goal of the facility for this funding period is to generate a library of novel NeuroMabs against neuronal proteins, initially focusing on membrane proteins (receptors/channels/transporters), synaptic proteins, other neuronal signaling molecules, and proteins with established links to disease states. The scope of the facility was expanded with supplements from the NIH Blueprint for Neuroscience Research to include neurodevelopmental targets, the NIH Roadmap for Medical Research to include epigenetics targets, and NIH Office of Rare Diseases Research to include rare disease targets. These NeuroMabs will then be produced on a large scale and made available to the neuroscience research community on an inexpensive basis as tissue culture supernatants or purified immunoglobulin by Antibodies Inc. The UC Davis/NIH NeuroMab Facility makes NeuroMabs available directly to end users and is unable to accommodate sales to distributors for third party distribution. Note, NeuroMab antibodies are now offered through antibodiesinc.

Proper citation: NeuroMab (RRID:SCR_003086) Copy   

•   Source: SciCrunch Registry

http://www.genetrap.org/

Consortium represents all publicly available gene trap cell lines, which are available on non-collaborative basis for nominal handling fees. Researchers can search and browse IGTC database for cell lines of interest using accession numbers or IDs, keywords, sequence data, tissue expression profiles and biological pathways, can find trapped genes of interest on IGTC website, and order cell lines for generation of mutant mice through blastocyst injection. Consortium members include: BayGenomics (USA), Centre for Modelling Human Disease (Toronto, Canada), Embryonic Stem Cell Database (University of Manitoba, Canada), Exchangeable Gene Trap Clones (Kumamoto University, Japan), German Gene Trap Consortium provider (Germany), Sanger Institute Gene Trap Resource (Cambridge, UK), Soriano Lab Gene Trap Resource (Mount Sinai School of Medicine, New York, USA), Texas Institute for Genomic Medicine - TIGM (USA), TIGEM-IRBM Gene Trap (Naples, Italy).

Proper citation: International Gene Trap Consortium (RRID:SCR_002305) Copy   

•   Source: SciCrunch Registry

http://swissbiobank.com/

With expertise in the preservation of biological specimens, Swiss Biobank is a biobank of cell therapy products (stem cells, progenitor). Strategically located in Suisse Romande, the center is accessible 7J/7J, 365 days / year. The laboratories and technology platforms are tailored to international standards. Service is prompt, courteous, and responsive to your needs. The first opportunity to harvest adult stem cells, which is the only type at Swiss Biobank, occurs just after the birth of a baby. The umbilical cord blood and placenta are rich in hematopoietic stem cells and can regenerate all cells in the bloodstream. The cord and placenta tissues themselves contain mesenchymal cells that can be used for the regeneration of connective tissue. The standardized procedures for collecting cord blood units are made ����??����??by the medical staff of the hospital / clinic according to international standards. The sample is transported by a courier Swiss Medical Biobank in which it is prepared and cryo-preserved by qualified personnel within 24 hours. In the case of public biobanking, cells, tissues, organs are donated and can be used with consent of the donor, a third person for transplantation, or as part of clinical research. The HLA (Human Leukocyte Antigen) is a group of proteins on the cell surface, and specific to each individual. This allows the immune system to distinguish our own cells for foreign elements (pathogens) that are likely to be attacked. Histocompatibility between the donor and recipient is of primary importance in organ transplantation, tissues and / or cells, to minimize the chances of rejection. There is one chance in four that two siblings have the same HLA code.

Proper citation: Swiss Biobank (RRID:SCR_004516) Copy   

•   Source: SciCrunch Registry

http://ccr.coriell.org/Sections/Collections/NIGMS/?SsId=8

Highly characterized cell lines and high quality DNA for cell and genetic research representing a variety of disease states, chromosomal abnormalities, apparently healthy individuals and many distinct human populations. The NIGMS Repository contains more than 10,600 cell lines, primarily fibroblasts and transformed lymphoblasts, and over 5,500 DNA samples. The NIGMS Repository has a major emphasis on heritable diseases and chromosomally aberrant cell lines. In addition, it contains a large collection dedicated to understanding human variation that includes samples from populations around the world, the CEPH collection, the Polymorphism Discovery Resource, and many apparently healthy controls. Human induced pluripotent stem cell lines, many of which were derived from NIGMS Repository fibroblasts, have recently become available through the NIGMS Repository. Sample donation facilitates all areas of research by making available well-characterized materials to any qualified researcher who might have otherwise been unable to invest the time and resources to collect needed samples independently. Donations to the Repository have created a resource of unparalleled scope. Samples from the collection have been used in more than 5,500 publications and are distributed to scientists in more than 50 countries. This resource is continuously expanding to support new directions in human genetics.

Proper citation: NIGMS Human Genetic Cell Repository (RRID:SCR_004517) Copy   

•   Source: SciCrunch Registry

http://www.bioreliance.com/biorepository.aspx

The BioReliance Biorepository offers secure cell storage of eukaryotic, prokaryotic and viral biological materials. Our vapor phase liquid nitrogen and -80����??C freezers offer complete flexibility and protection. Each bank is certified free from mycoplasma and tested for sterility prior to storage and then divided and stored in separate validated vessels. Our continuously monitored facilities in US and UK follow cGMP.

Proper citation: BioReliance Biorepository (RRID:SCR_004598) Copy   

•   Source: SciCrunch Registry

http://www.stemhealth.eu/

An accredited cord blood bank and stem cell bank in Europe. Services offered include family cord blood banking, public banking, directed allogeneic transplantation, umbilical cord tissue banking and HLA typing.

Proper citation: Stem-Health Hellas Stem Cell Bank (RRID:SCR_004476) Copy   

•   Source: SciCrunch Registry

http://dctd.cancer.gov/

Division of NCI that takes prospective cancer detection and treatment leads, facilitates their paths to clinical application, and expedites the initial and subsequent large-scale testing of new agents, biomarkers, imaging tests, and other therapeutic interventions (radiation, surgery, immunotherapy) in patients. DCTD, like all of NCI, supports many programs that could not be done without government funding - investigators supported by the division engage in scientifically sound, high-risk research that may yield great benefits for patients with cancer, but are too difficult or risky for industry or academia to pursue. This includes a particular emphasis on the development of distinct molecular signatures for cancer, refined molecular assays, and state-of-the-art imaging techniques that will guide oncologic therapy in the future. The division has eight major programs that work together to bring unique molecules, diagnostic tests, and therapeutic interventions from the laboratory bench to the patient bedside: * Cancer Diagnosis Program * Cancer Imaging Program * Cancer Therapy Evaluation Program * Developmental Therapeutics Program * Radiation Research Program * Translational Research Program * Biometrics Research Branch * Office of Cancer Complementary and Alternative Medicine

Proper citation: DCTD (RRID:SCR_004196) Copy   

•   Source: SciCrunch Registry

http://www.portugene.com/SPInDel/SPInDel_webworkbench.html

A multifunctional workbench for species identification using insertion/deletion variants. The SPInDel workbench provides a step-by-step environment for the alignment of target sequences, selection of informative hypervariable regions, design of PCR primers and the statistical validation of the species-identification process. It includes a large dataset comprising nearly 1,800 numeric profiles for the identification of eukaryotic, prokaryotic and viral species.

Proper citation: SPInDel (RRID:SCR_004509) Copy   

•   Source: SciCrunch Registry