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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.uc.edu/labs/mmpc.html
Research center that provides metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders. It specializes in the immunological aspects of Type I diabetes, measurement of various glucose and lipid metabolism parameters relevant to Type II diabetes as well as diabetic complications such as heart disease and obesity.
Proper citation: MMPC-University of Cincinnati Medical Center (RRID:SCR_015367) Copy
Research center whose focus is on developing effective gene vectors derived from recombinant viruses. Much of their research is in the development of new adeno-associated virus (AAV) vectors, although some of their research involves both adenoviruses and lentiviruses.
Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis (RRID:SCR_015406) Copy
http://livercenter.yale.edu/index.aspx
Research center which supports investigation of liver structure, function and disease through access to its four core facilities (Administrative, Physiology, Clinical and Translational, and Morphology cores) and Pilot Feasability Projects.
Proper citation: Yale Liver Center (RRID:SCR_015255) Copy
https://labnodes.vanderbilt.edu/mmpc
Research center whose mission is to advance research in the area of diabetes by providing experimental tools to the scientific community for phenotyping mouse transgenic models of diabetes and related disorders.
Proper citation: MMPC-Vanderbilt University School of Medicine (RRID:SCR_015374) Copy
https://medicine.uiowa.edu/genetherapy/
Research center which provides access to core facilities and services to aid gene therapy researchers.
Proper citation: University of Iowa Center for Gene Therapy (RRID:SCR_015412) Copy
Research center whose purpose is to advance research in digestive disease with a focus on interactions between host and environment. It provides research resources to basic and translational investigators through various core facilities.
Proper citation: Washington University Digestive Diseases Research Core Center (RRID:SCR_015252) Copy
http://www.med.unc.edu/cgibd/cores/gnotobiotic
Core facility that supports animal model and basic research projects of CGIBD investigators. Investigators use this resource to examine physiologic and pathophysiologic differences in germ-free, gnotobiotic, and specific pathogen free colonized mice of various genetic backgrounds.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Gnotobiotic Core (RRID:SCR_015615) Copy
http://www.med.upenn.edu/molecular/
Center that aims to unite investigators with interests in digestive, liver and pancreatic physiology and disease in the exploration of creative experimental approaches. The scientific focus of the Center revolves around the molecular controls of cellular growth and differentiation in the digestive tract, liver and pancreas with the goal of achieving a new level of integration in biology, pathobiology, and therapy.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases (RRID:SCR_015617) Copy
Center that aims to advance basic science and translational digestive diseases research at the Johns Hopkins University School of Medicine. Its goal is to improve the health of patients with the broad spectrum of gastrointestinal and hepatic disorders.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center (RRID:SCR_015589) Copy
http://www.med.upenn.edu/genetics/tcmf/
Core facility that provides a centralized service to efficiently produce genetically altered mice for basic research, resulting in reduction in effort and cost to participating investigators.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Genetically-Modified Mouse Core (RRID:SCR_015622) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/translationalResearchEnhancementCore.html
Core facility whose services include establishing Best Practices (BP) and uniform Standard Operating Procedures (SOPs) for the collection, annotation, processing, storage, management, distribution, and ethical use of human specimens, and to provide access to specimens by investigators as well as patient identification, patient recruitment, facilitation of patient trials, translational research and basic research through creation of a patient registry and database.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Translational Research Enhancement Core (RRID:SCR_015594) Copy
https://www.niddk.nih.gov/research-funding/research-programs/kidney-disease-centers
Portal with detailed information about various research centers that focus on pediatric medicine and nephrology. These centers are funded by NIDDK.
Proper citation: Pediatric Centers of Excellence in Nephrology (RRID:SCR_015721) Copy
Center at UNC Chapel Hill and North Carolina State University for collaborative GI research. Its mission is to promote and enhance multidisciplinary digestive disease research.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease (RRID:SCR_015612) Copy
PERL is a clinical trial for people with type 1 diabetes who have early signs of kidney problems. Its goal is to test a new way to reduce loss of kidney function using a safe and inexpensive medicine.
Proper citation: Preventing Early Renal Loss in Diabetes (PERL) (RRID:SCR_015862) Copy
A Web-based Analysis Tool for Indirect Calorimetry Experiments which measure physiological energy balance. It is a web application for indirect calorimetry analysis which generates customizable time, bar and regression plots for calorimetry data using two-, three-, and four-group templates.
Proper citation: CalR (RRID:SCR_015849) Copy
https://www.sciencescott.com/pyminer
Software tool to automate cell type identification, cell type-specific pathway analyses, graph theory-based analysis of gene regulation, and detection of autocrine-paracrine signaling networks. Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.
Proper citation: PyMINEr (RRID:SCR_016990) Copy
https://www.nature.com/articles/s41467-018-03367-w
Nanodroplet processing platform for deep and quantitative proteome profiling of 10 to 100 mammalian cells. It enhances efficiency and recovery of sample processing by downscaling processing volumes.
Proper citation: nanoPOTS (RRID:SCR_017129) Copy
Ratings or validation data are available for this resource
https://www.zurich.ibm.com/cellcycletracer/
Software tool as supervised machine learning algorithm that classifies and sorts single cell mass cytometry data according to their cell cycle, which allows to correct for cell cycle state and cell volume heterogeneity. Reveals signaling relationships and cell heterogeneity that were otherwise masked. Computational method to quantify cell cycle and cell volume variability.
Proper citation: CellCycleTRACER (RRID:SCR_017128) Copy
https://github.com/epistasislab/hibachi
Software tool that creates data sets with particular characteristics. Method and open source software for simulating complex biological and biomedical data to aid in comparing and evaluating machine learning methods.
Proper citation: Heuristic Identification of Biological Architectures for simulating Complex Hierarchical Interactions (RRID:SCR_017140) Copy
https://hirnetwork.org/consortium/cmai
Consortium that is an independent research initiative of the Human Research Information Network (HIRN). It is developing innovative approaches to model basic aspects of human T1D immunobiology using novel in vivo and in vitro platforms.
Proper citation: HIRN Consortium on Modeling Autoimmune Interactions (RRID:SCR_016200) Copy
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