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https://syllabus.med.unc.edu/courseware/embryo_images/
Tutorial that uses scanning electron micrographs (SEMs) as the primary resource to teach mammalian embryology. The 3-D like quality of the micrographs coupled with selected line drawings and minimal text allow relatively easy understanding of the complex morphological changes that occur in utero. Because early human embryos are not readily available and because embryogenesis is very similar across mammalian species, the majority of micrographs that are utilized in this tutorial are of mouse embryos. The remainder are human. This tutorial is divided into units that may be studied in any order. All of the images have a legend that indicates the age of the embryo. If it is a mouse embryo, the approximate equivalent human age is indicated. To minimize labeling, color-coding is widely used. To view the micrographs without color, the cursor may be placed on the image. The SEMs used in this tutorial are from the Kathleen K. Sulik collection. The line drawings have been used with permission from Lippincott Williams & Wilkins and are from the 6th and 7th editions of Langman''s Medical Embryology by T.W. Sadler.
Proper citation: Embryo Images Normal and Abnormal Mammalian Development (RRID:SCR_006297) Copy
http://www.niaid.nih.gov/topics/alps/Pages/default.aspx
A disease-related portal about Autoimmune Lymphoproliferative Syndrome (ALPS) including research in the following categories: Medical and Genetic Description, Database of Mutations, Database of ALPS-FAS Mutations, and Molecular Pathways. Autoimmune Lymphoproliferative Syndrome (ALPS) is a recently recognized disease in which a genetic defect in programmed cell death, or apoptosis, leads to breakdown of lymphocyte homeostasis and normal immunologic tolerance. It is an inherited disorder of the immune system that affects both children and adults. In ALPS, unusually high numbers of white blood cells called lymphocytes accumulate in the lymph nodes, liver, and spleen, which can lead to enlargement of these organs. Database of Mutations * All existing ALPS-FAS mutations (NIH Web site) * ALPS-FAS * ALPS Type Ia (most common type) ** Reported FAS (TNFRSF6) mutations causing ALPS ** Distribution of FAS (TNFRSF6) mutations ** FAS (TNFRSF6) polymorphisms * ALPS Type II
Proper citation: Autoimmune Lymphoproliferative Syndrome Information (RRID:SCR_006451) Copy
http://buridan.sourceforge.net/
Open source software written in R that tracks a single animal walking in a homogenous environment (Buritrack) and analyzes its trajectory. It extracts eleven metrics and includes correlation analyses and a Principal Components Analysis (PCA). It was designed to be easily customized to personal requirements. In combination with inexpensive hardware, these tools can readily be used for teaching and research purposes. Buritrack is a program to track individual Drosophila fruit flies online with any camera as they walk in Buridan's paradigm. The program extracts the coordinate locations of the fly and stores them in a text file.
Proper citation: Centroid Trajectory Analysis (RRID:SCR_006331) Copy
A social visualization repository for the scientific workflow management system VisTrails providing a platform for sharing and executing computational tasks. It adopts the model used by social Web sites and that integrates a set of usable tools and a scalable infrastructure to provide an environment for scientists to collaboratively analyze and visualize data. crowdLabs aims to foster collaboration but was specifically designed to support the needs of computational scientists, including the ability to access high-performance computers and manipulate large volumes of data. By providing mechanisms that simplify the publishing and use of analysis pipelines, it allows IT personnel and end users to collaboratively construct and refine portals. This lowers the barriers for the use of scientific analyses and enables broader audiences to contribute insights to the scientific exploration process, without the high costs incurred by traditional portals. In addition, it supports a more dynamic environment where new exploratory analyses can be added on-the-fly.
Proper citation: crowdLabs (RRID:SCR_006294) Copy
http://www.animalgenome.org/pig/genome/db/
Database facilitating information integration and mining within the pig and across species of all genomics / genetics research results accumulated over the years including pig gene expression, quantitative trait loci (QTL), candidate gene, and whole genome association study (WGAS) results. The key functions developed so far include pig gene pages (a centralized gene search tool), a local copy of Biomart (for customizable genome information queries), genome feature alignment tools (Pig QTLdb and Gbrowse), integrated gene expression information (ANEXDB and ESTdb), a dedicated pig genome and gene set BLAST server, and virtual comparative map database and tools (VCmap). By developing the PGD, it is our aim to collaboratively utilize existing databases and tools via networked functions, such as web services, database API, etc., to maximize the potential of all related databases through the PGD implementation.
Proper citation: Pig Genome Database (RRID:SCR_006367) Copy
http://www.fmriconsulting.com/brodmann/
An atlas that facilitates fMRI analysis understanding by providing access to all of the functions that have been associated with each of the 52 Brodmann's areas or corresponding gyri. Links to main publications supporting the findings are provided in PubMed ID format. Brodmann's areas with similar functions and locations have been collapsed into a single page. The word left or right has been added indicating a lateralized function. All the abstracts published on PubMed on fMRI and brain PET studies in which the Brodmann's area or its anatomical correlate were mentioned have been reviewed up to August 2008. Abstracts with poorly described experimental methods or findings clearly conflicting with established knowledge provided by the clinical model were excluded. Studies on patients were also excluded.
Proper citation: Brodmann's Interactive Atlas (RRID:SCR_006368) Copy
http://www.pathpedia.com/Default.aspx
Pathpedia.com is web-based wiki on human anatomical, clinical, and experimental pathology created for pathologists. This collaborative portal includes news, education, jobs, meetings, forums and links. The Education tab includes access to journals, books, CME / SAM/ CMIL, WikiBooks, eAtlas, etc. The eAtlas module allows you post unusual and difficult pathology cases to be reviewed by other pathologists across the globe. This module may help in identifying previously unreported entities and unusual / variant examples of known entities. Categories include Histopathology, Gross pathology, Normal histology, Image quiz and Case sharing. Immunopedia - A clinically useful web-based database on the immunohistochemical and flow cytometric evaluation of neoplasms. 1. Large database 2. Regular updates 3. Quality citations 4. Exquisite modules *Data included for both neoplastic & non-neoplastic tissues/cells *Clones indicated wherever applicable along with their markers *References cited for each piece of data on markers or diseases *Option provided to merge data of discrete disease categories Online case sharing *Share unusual cases with pathology community *Help identify previously unreported entities *Get expert reviews and comments from your peers
Proper citation: Pathpedia.com - Online pathology resource (RRID:SCR_006482) Copy
Collection of chemical structures. Provides access to structures, properties and associated information from hundreds of data sources to find compounds of interest and provides services to improve this data by curation and annotation and to integrate it with users applications.
Proper citation: ChemSpider (RRID:SCR_006360) Copy
Software application to create Open Data from your Google Drive spreadsheets. # Create a spreadsheet in Google Drive. Share, collaborate and refine your data as usual. # Design the template in EasyOpenData. Format your data the way you want it - any markup, any schema. # Publish your Open Data feed. Feeds update automatically when your spreadsheet is changed.
Proper citation: EasyOpenData (RRID:SCR_006354) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Project to advance understanding of the neural mechanisms of vocal learning by providing a quantitative description of the relationship between physiological variables and vocal performance over the course of development in a songbird, the zebra finch. They propose to study vocal learning dynamically across neuronal and peripheral subsystems, using a novel collaborative approach that will harness the combined expertise of several investigators. Their proposed research model will 1) provide simultaneous measurements of acoustic, articulatory and electrophysiological data that will document the detailed dynamics of the vocal imitation process in a standardized learning paradigm; and 2) incorporate these measurements into a theoretical/computational framework that simultaneously provides a phenomenological description and attempts to elucidate the mechanistic basis of the learning process.
Proper citation: Zebra Finch Song Learning Consortium (RRID:SCR_006356) Copy
Web server to identify statistically enriched pathways, diseases, and GO terms for a set of genes or proteins, using pathway, disease, and GO knowledge from multiple famous databases. It allows for both ID mapping and cross-species sequence similarity mapping. It then performs statistical tests to identify statistically significantly enriched pathways and diseases. KOBAS 2.0 incorporates knowledge across 1327 species from 5 pathway databases (KEGG PATHWAY, PID, BioCyc, Reactome and Panther) and 5 human disease databases (OMIM, KEGG DISEASE, FunDO, GAD and NHGRI GWAS Catalog). A standalone command line version is also available, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: KOBAS (RRID:SCR_006350) Copy
A production service that gives researchers the ability to create and manage long-term identifiers so that they can to track usage, get credit for their work, share their data, and have the data reused for additional research. As a result, EZID identifiers also make it possible to increase citations, to build on previous work, to conduct new research, and avoid duplicating previous efforts. EZID identifiers provide a simple but powerful way to track research materials, including datasets, throughout their life cycle. In this way, researchers can share their data, get more citations, and track their results.
Proper citation: EZID (RRID:SCR_006473) Copy
An open-source, open-process, open-access scholarly authoring and publishing platform based on WordPress. Its objectives are to develop a simple, robust, easy-to-use authoring system to create and edit scholarly articles, and to deliver an editorial review and publishing system that can be used to submit, review, and publish scholarly articles. Software and source code are also available. Annotum will build upon the WordPress platform as a foundation, filling in the gaps by providing the following additional features: * Rich, web-based authoring and editing: ** What you see is what you get (WYSIWYG) authoring with rich toolset (equations, figures, tables, citations and references) ** coauthoring, comments, version tracking, and revision comparisons * Strict conformance to a subset of the NLM journal article publishing tag set * Multiple import and export formats ** Export to PDF and XML formats ** Import XML and WXR formats for round-tripping of content ** Articles can be cited, exported, imported across systems/sites * Simple editorial workflow for authoring and reviewer/editor approval * Features specific to scholarly publishing: ** Equations, figures, tables ** References including citation search features ** Auto-generation and registration of CrossRef DOIs
Proper citation: Annotum (RRID:SCR_006353) Copy
http://www.centropiaggio.unipi.it/software
Software to handle and process large numbers of optical microscopy image files of neurons in culture or slices in order to automatically run batch routines, store data and apply multivariate classification and feature extraction using 3-way principal component analysis (PCA). This freeware for semi automated quantitative and dynamic analysis of neuron morphometry incorporates the most important microstructural quantification methods, such as fractal and sholl analysis with statistical and classification tools to provide an integrated image processing environment which enables fast and easy feature identification. It includes: * Friendly interactive graphical user interface * Image pre-processing * Morphological analysis * Topological analysis * Cell counting * 3-way PCA analysis (also available as an ImageJ plugin) * Plot of variables Sequential images of labeled or unlabelled neurons or tissue slices can be uploaded batch-wise in order to create a 3 axis (time, image coordinate) data base and a datamatrix of variables for 3-way Principal Component Analysis*.
Proper citation: NEuronMOrphological analysis tool (RRID:SCR_006304) Copy
An ontology for the description of biological and clinical investigations built with international, collaborative effort. The ontology represents the design of an investigation, the protocols and instrumentation used, the material used, the data generated and the type analysis performed on it. This includes a set of universal terms that are applicable across various biological and technological domains, and domain-specific terms relevant only to a given domain. Currently OBI is being built under the Basic Formal Ontology (BFO). This project was formerly titled the Functional Genomics Investigation Ontology (FuGO) project.
Proper citation: Ontology for Biomedical Investigations (RRID:SCR_006266) Copy
The LBDA is a Lewy Body Disease (LBD) information resource for lewy body patients, caregivers, and medical professionals. It provides general information on LBD, including diagnosis, symptoms, treatments, etc., as well as providing links to support resources and an LBD online community. For professionals, the site also provides information on patient care, current LBD research and publications, and diagnostics information. LBDA offers many support resources for those affected by LBD and for their loved ones. These resources include local support group meeting information, online support groups, and user forums where users can find information or ask any questions they may have about the disease. A portion of the site is also dedicated to those who wish to help, either through participation in clinical trials, donations, or volunteering. LBDA also offers information on upcoming LBD-related events. LBDA is located Atlanta, GA. :NIF thanks the : :Parkinson''s Disease Foundation : : :for their referral of this resource to us.
Proper citation: Lewy Body Dementia Association (RRID:SCR_006421) Copy
Data and knowledge management infrastructure for the new Center for Clinical and Translational Science (CCTS) at the University of Utah. This clinical cohort search tool is used to search across the University of Utah clinical data warehouse and the Utah Population Database for people who satisfy various criteria of the researchers. It uses the i2b2 front end but has a set of terminology servers, metadata servers and federated query tool as the back end systems. FURTHeR does on-the-fly translation of search terms and data models across the source systems and returns a count of results by unique individuals. They are extending the set of databases that can be queried.
Proper citation: FURTHeR (RRID:SCR_006383) Copy
Software application that supports the execution of multivariable prediction models with patient-specific characteristics so that personalized estimates of outcomes, often as a function of alternative treatments, can be generated within the routine flow of patient care. This can support evidence-based, shared medical decision-making to improve the safety, outcomes and cost-effectiveness of care. The current application is in the setting of generating individualized informed consent documents for PCI. However, the tool can support that translation of novel biomarkers, genetics and pharmacogenomic interactions into clinical care. The platform gives healthcare providers instantaneous access to the latest clinical prediction models coupled with rich visualization tools. These models may come from national organizations, outcomes researchers or a specific institution. In addition to decision support applications, it can be used to rapidly create personalized educational materials, patient letters, informed consent documents and a broad array of other items that can help elevate the quality of healthcare delivery.
Proper citation: ePRISM (RRID:SCR_006386) Copy
http://brainvis.wustl.edu/wiki/index.php/Caret:About
Software package to visualize and analyze structural and functional characteristics of cerebral and cerebellar cortex in humans, nonhuman primates, and rodents. Runs on Apple (Mac OSX), Linux, and Microsoft Windows operating systems.
Proper citation: Computerized Anatomical Reconstruction and Editing Toolkit (RRID:SCR_006260) Copy
A community building portal dedicated to understanding Alzheimer's disease and related disorders, it reports on the latest scientific findings from basic research to clinical trials, creates and maintains public databases of essential research data and reagents, and produces discussion forums to promote debate, speed the dissemination of new ideas, and break down barriers across disciplines.
Proper citation: Alzheimer's Research Forum (RRID:SCR_006416) Copy
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