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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://cran.r-project.org/web/packages/flexmix/index.html
Software R package for finite mixtures of regression models using EM algorithm. General framework for finite mixture models and latent class regression in R.
Proper citation: flexmix (RRID:SCR_027152) Copy
https://assets.fishersci.com/TFS-Assets/LSG/Application-Notes/7500-Fast-Dx-brochure.pdf
Real-Time PCR Instrument, with Sequence Detection System (SDS) Software, is 96-well, 5-color real-time PCR instrument available for in vitro diagnostic use. Based on Peltier block technology, instrument is designed to deliver results, in 96-well format. SDS Software allows full control over thermal cycling protocols to further assist in developing or running custom assays.
Proper citation: Thermo Fisher: Applied Biosystems: 7500 Fast Dx Real-Time PCR Instrument (RRID:SCR_027081) Copy
https://www.mybeckman.ca/flow-cytometry/research-flow-cytometers/cytoflex-lx/c40313
Flow Cytometer has 5 active lasers (375 nm, 405 nm, 488 nm, 561 nm, 638 nm) and 19 channels for fluorescence detection. This instrument can be upgraded with a maximum of 3 Near UV, 5 Violet, 3 Blue, 3 Red, and 2 Infrared channels. It includes 21 repositionable bandpass filters, 405/10, 450/45 (2), 525/40 (3), 585/42, 610/20 (3), 660/10 (2), 675/30 (2), 690/50, 710/50, 712/25, 763/43 (3), 840/20, 885/40. The complete system is supplied with computer work station with CytExpert Acquisition software, sheath and waste containers with harness.
Proper citation: Beckman Coulter: CytoFLEX LX N3-V5-B3-Y5-R3-I0 Flow Cytometer (RRID:SCR_027084) Copy
https://cran.r-project.org/web/packages/BAMMtools/index.html
Software R package for analysis and visualization of macroevolutionary dynamics on phylogenetic trees.
Proper citation: BAMMtools (RRID:SCR_027137) Copy
https://www.bruker.com/en/products-and-solutions/mass-spectrometry/mrms/solarix.html
Bruker solariX is magnetic resonance mass spectrometry (MRMS) platform, available with high-field magnets ranging from 7 T up to 15 T.
Proper citation: Bruker: solariX (RRID:SCR_027095) Copy
https://www.microscopesinternational.com/default.aspx
Microscopes International (often branded as “uScope” by Microscopes International) is a Plano, Texas–based company (est. 2009) specializing in affordable, highly portable digital microscopes and whole‑slide scanning systems for scientific, clinical, and field applications.
Proper citation: Microscopes International (RRID:SCR_027094) Copy
https://www.bdbiosciences.com/zh-cn/products/instruments/single-cell-multiomics-systems/rhapsody
System allows high-throughput capture of multiomic information from single cells using cartridge workflow and multitier barcoding system. Used for high-throughput, multiomic profiling of single cells. Allows to analyze gene expression at both mRNA and protein levels, as well as other cellular characteristics, using microwell-based system with multitiered barcoding approach.This enables the generation of various next-generation sequencing (NGS) libraries for deeper analysis.
Proper citation: BD Biosciences: Rhapsody Single-Cell Analysis System (RRID:SCR_027096) Copy
https://www.leica-microsystems.com/fr/produits/microscopie-optique/stereomicroscopes/p/leica-m80/
Leica M80 is modular, ergonomic zoom stereomicroscope designed for range of routine applications in life sciences and industrial settings. It features 8:1 zoom range, providing continuous zoom from 7.5x to 60x, and is known for its high resolution, large field of view, and increased depth of focus. M80 is particularly well-suited for tasks like inspection, photography, and measurement of samples such as circuit boards, hairs, fibers, and biological tissues.
Proper citation: Leica: M80 Stereomicroscope (RRID:SCR_027099) Copy
https://github.com/gillislab/MetaMarkers
Software R package to efficiently compute robust markers across single-cell datasets. Robust marker signatures from single-cell data.
Proper citation: MetaMarkers (RRID:SCR_027104) Copy
https://cytekbio.com/pages/aurora-cs
Advanced and adaptable cell sorting system employs Full Spectrum Profiling technology to produce high-quality flow cytometric data along with Cytek portfolio of full spectrum instruments. Aurora CS system is the only commercially available spectral cell sorter that is paired with companion analyzer.
Proper citation: CyTekBio: Aurora CS system (RRID:SCR_027060) Copy
https://caravagnalab.github.io/CNAqc/
Software package to quality control bulk cancer sequencing data. Used to visualise and manipulate i) somatic mutation data of both single-nucleotide variants and insertion-deletions, ii) allele-specific Copy Number Alterations (CNAs) and iii) tumour purity estimates. Used to validate copy number segmentations against variant allele frequencies of somatic mutations. Provides automatic copy number calling pipeline. Provides also algorithms to phase mutation multiplicities against CNAs and estimate Cancer Cell Fractions (CCFs) with their uncertainty.
Proper citation: CNAqc (RRID:SCR_027066) Copy
https://www.biotanon.com/Product/ProductList?id=318&type=Detail
Tanon series chemiluminescence image analysis system equipped with advanced scientific research-grade cooling CCD and professional lens with fully automatic mechanical one-key switch various shooting modes, can be used for chemiluminescence, multi-color fluorescence, visible light, ultraviolet fluorescence detection to provide sample images.
Proper citation: BioTanon: 5200 Series Automatic Image Analysis System (RRID:SCR_027114) Copy
https://cran.r-project.org/web/packages/babelgene/index.html
Software R package to convert between human and non-human gene orthologs/homologs. Integrates orthology assertion predictions sourced from multiple databases as compiled by the HGNC Comparison of Orthology Predictions (HCOP) (Wright et al. 2005 , Eyre et al. 2007 , Seal et al. 2011 ).
Proper citation: babelgene (RRID:SCR_027117) Copy
Thermal cycler with flexible configuration and control features. System with Thermo Fisher Connect to design and upload methods and monitor runs from any smartphone or desktop computer. Has five different blocks that can be changed. Blocks allow up to three experiments to be run simultaneously, completely independently of each other and without interference. Dual 96-well and dual 384-well blocks are available for your high-throughput PCR sequencing needs, and dual flat block is available to support Applied Biosystems OpenArray plate technology for genotyping analysis on the Applied Biosystems QuantStudio 12K Flex Real-Time PCR System.
Proper citation: Thermo Fisher: Applied Biosystems: ProFlex PCR System (RRID:SCR_027077) Copy
https://carinadocs.stanford.edu/
Shared on-premises computing cluster with security controls for high-risk data, managed by Stanford Research Computing. Carina contains base set of shared compute and storage resources available to Stanford researchers working with high-risk data (PHI, PII, etc.), with additional dedicated capacity available for purchase.
Proper citation: Carina (RRID:SCR_027110) Copy
https://bioconductor.org/packages/release/bioc/html/UCell.html
Software package for evaluating gene signatures in single-cell datasets. UCell signature scores, based on the Mann-Whitney U statistic, are robust to dataset size and heterogeneity, and their calculation demands less computing time and memory than other available methods, enabling the processing of large datasets in a few minutes even on machines with limited computing power. UCell can be applied to any single-cell data matrix, and includes functions to directly interact with SingleCellExperiment and Seurat objects.
Proper citation: UCell (RRID:SCR_027109) Copy
Organization is part of a strategic global community effort to promote transparent and trustworthy research practices in the academic research systems. Part of the Association of African Universities.
Proper citation: African Reproducibility Network (RRID:SCR_027167) Copy
E11 Bio was launched in 2022 as one of the first Focused Research Organizations (FROs), a novel form of non-profit startup for science. E11 Bio’s mission is to unlock connectomics at the scale of whole mammalian brains by radically cheaper and more accessible technologies.
Proper citation: E11 Bio (RRID:SCR_027166) Copy
https://www.imebinc.com/product/leica-rm-2035-microtome/
Leica RM 2035 BioCut Manual Microtome is perfect for manually sectioning paraffin or plastic-embedded specimens.
Proper citation: Leica: Microtome RM2035 (RRID:SCR_027202) Copy
https://www.bio-techne.com/p/imaging/fluorchem-r-system_92-15313-00
System was high-performance gel imaging system for chemiluminescence, fluorescence, UV, and visible light applications, but it has been discontinued as of October 15, 2021. ProteinSimple (now part of Bio-Techne) will continue servicing these products through October 15, 2026.
Proper citation: Bio-Techne: ProteinSimple FluorChem R System (RRID:SCR_027216) Copy
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