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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | ||||||||||||||
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Zymo Genetics Resource Report Resource Website 100+ mentions |
Zymo Genetics (RRID:SCR_008602) | data or information resource, organization portal, portal | Founded in 1981, ZymoGenetics is a biopharmaceutical company focused on the development and commercialization of therapeutic proteins. ZymoGenetics is publicly traded (NASDAQ: ZGEN) and headquartered in Seattle, Washington in the historic Seattle City Light Steam Plant building. Our mission is to create novel protein drugs that will significantly help patients fight their diseases. We have contributed to the discovery or development of six recombinant protein products now marketed by other companies. Current programs target viral infection, cancer, inflammatory diseases and bleeding. Our first internally developed product, RECOTHROM Thrombin, topical (Recombinant), was approved by the U.S. Food and Drug Administration (FDA) on January 17, 2008 for use as a topical hemostat to control moderate bleeding during surgical procedures and is now marketed in the United States. We have a promising pipeline of novel therapeutics, which we are developing on our own or in collaboration with partners. | nif-0000-31937 | SCR_008602 | SciCrunch Registry | Zymo | 2026-10-10 12:42:33 | 114 | |||||||||||
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Medical College of Georgia Animal Behavior Center Resource Report Resource Website |
Medical College of Georgia Animal Behavior Center (RRID:SCR_008049) | analysis service resource, behavioral analysis service, production service resource, service resource | The Medical College of Georgia Animal Behavior Center has considerable experience testing the short-term memory and attention capabilities of non-human primates. Testing programs are available to MCG faculty on a collaborative basis, and they are available for contractual agreements with pharmaceutical companies and other external research programs. Delayed-response testing is a well-established means of examining neurochemical, neuroanatomical and therapeutic aspects of ATD, ADHD and schizophrenia. Behavioral paradigms at the Animal Behavior Center are designed around an automated delayed-response task assessing the function of mnemonic and attention processes. Particularly significant is the fact that each paradigm differs regarding the relative emphasis on these two different, yet interdependent, cognitive constructs. The Animal Behavior Center also is experienced in stereotaxic implantation of intracranial electrodes and cannulas in rodents and non-human primates. The basic approaches and procedures of the Animal Behavior Center include: - Delayed Matching-to-Sample (DMTS) - DMTS With a Distractor During the Delay Interval - DMTS With a Titrated Delay Interval | electrode, adhd, animal, atd, attention, behavior, behavioral, cannula, cognitive, delayed-response, implantation, intracranial, mnemonic, neuroanatomical, neurochemical, non-human primate, pharmaceutical, rodent, schizophrenia, short-term memory, sterotaxic, therapeutic | has parent organization: Medical College of Georgia; Georgia; USA | nif-0000-10289 | http://www.georgiahealth.edu/centers/alz/ | SCR_008049 | SciCrunch Registry | Animal Behavior Center | 2026-10-10 12:43:29 | 0 | ||||||||
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CLEAVE Resource Report Resource Website 10+ mentions |
CLEAVE (RRID:SCR_007113) | CLEAVE | data processing software, software application, software resource | A UNIX-style command-line program which quickly computes multifactorial ANOVAs for very large data sets with minimal memory use (without loading all of the data into memory). It has been used for fMRI analysis, e.g. CLEAVE adds the following to the standard ANOVA analyses: # Unlimited numbers of factors can be analyzed. # Factor Correlation and Unequal Variance Corrections # Treatment Magnitudes: omega^2, partial eta^2, and R^2 # A convenient Ranking of Factors based upon treatment magnitudes and significance levels. # Post-Hoc Significance Tests # Post-Hoc Power Table to gauge how many subjects will be needed to achieve significance. # Allows the use of Random Factors. # A Configuration File to make the program more tunable # A Histogram and Cell Line Diagrams: which help the user to detect outliers. # Associated MATLAB functions: port CLEAVE-style data sets in or out of MATLAB. | c, console (text based), macos, microsoft, magnetic resonance, posix/unix-like, statistical operation |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) has parent organization: University of California at Davis; California; USA |
Creative Commons Attribution License | nlx_155530 | http://www.nitrc.org/projects/cleave | SCR_007113 | SciCrunch Registry | 2026-10-10 12:42:31 | 17 | |||||||
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UW Genome Sciences Resource Report Resource Website 10+ mentions |
UW Genome Sciences (RRID:SCR_008562) | data or information resource, organization portal, portal | Welcome to the Department of Genome Sciences, which began in September 2001 by the fusion of the Departments of Genetics and Molecular Biotechnology. Our goal is to address leading edge questions in biology and medicine by developing and applying genetic, genomic and computational approaches that take advantage of genomic information now available for humans, model organisms and a host of other species. Our faculty study a broad range of topics, including the genetics of E. coli, yeast, C. elegans, Drosophila, and mouse; human and medical genetics; mathematical, statistical and computer methods for analyzing genomes, and theoretical and evolutionary genetics; and genome-wide studies by such approaches as sequencing, transcriptional and translational analysis, polymorphism detection and identification of protein interactions. Our chair, Dr. Robert Waterston, joined the department in January 2003. Our department includes both faculty with primary appointments in Genome Sciences, as well as adjuncts in other departments and Seattle institutions. Nine faculty are members of the National Academy of Sciences, including 2001 Nobel Prize winner Dr. Lee Hartwell, who conducted much of his groundbreaking work in the Department of Genetics. Five training faculty are Howard Hughes Medical Institute Investigators. Graduate research in the Department leads to a Ph.D. in Genome Sciences and students may also choose to participate in the Computational Molecular Biology or Molecular Medicine programs. Our department has around 55 - 60 graduate students at any given time and has moved into the new William H. Foege Building. | has parent organization: University of Washington; Seattle; USA | nif-0000-31441 | SCR_008562 | SciCrunch Registry | UW Genome Sciences | 2026-10-10 12:42:33 | 39 | ||||||||||
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COILS: Prediction of Coiled Coil Regions in Proteins Resource Report Resource Website 100+ mentions |
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) | data processing software, software application, software resource | COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. | software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list |
is listed by: 3DVC is listed by: Debian is listed by: bio.tools is listed by: OMICtools |
DOI:10.1126/science.252.5009.1162 | biotools:ncoils, OMICS_07850, nif-0000-30263 | https://bio.tools/ncoils, https://sources.debian.org/src/ncoils/ | https://sources.debian.org/src/ncoils/ | SCR_008440 | SciCrunch Registry | COILS Server | 2026-10-10 12:43:29 | 169 | ||||||
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Visual Statistics Group Resource Report Resource Website 100+ mentions |
Visual Statistics Group (RRID:SCR_008317) | data or information resource, organization portal, portal | The general goal is to achieve a deeper understanding of natural image statistics because from this knowledge it should be possible to explain the behavior of the visual cortex and propose new alternatives in a number of applications in image processing and computer vision in which the basic problem is the choice of an appropriate signal representation. The range of basic and applied topics in which we are currently working include: * Mathematical models of human vision * Statistical image models * Image distortion metrics * Image coding * Motion estimation * Video coding * Image restoration * Color representation | behavior, color, cortex, human, mathematical, natural, statistic, visual, image | nif-0000-24683 | SCR_008317 | SciCrunch Registry | VISTA | 2026-10-10 12:42:32 | 447 | ||||||||||
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International Stroke Database/Software Resource Report Resource Website |
International Stroke Database/Software (RRID:SCR_007348) | data processing software, software application, software resource | Diffusion tensor imaging (DTI) tractography: An automated system for etiologic classification of ischemic stroke -- Causative Classification System for Ischemic Stroke DTI Task Card for Siemens systems, DTI Visualization platform independent tool kit, PWI analysis tools for bolus-tracking data |
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; has parent organization: Harvard University; Cambridge; United States |
nif-0000-00253 | SCR_007348 | SciCrunch Registry | International Stroke Database/Software | 2026-10-10 12:43:28 | 0 | ||||||||||
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TrakEM2 Resource Report Resource Website 100+ mentions |
TrakEM2 (RRID:SCR_008954) | TrakEM2 | data processing software, image analysis software, software application, software resource | An ImageJ plugin for morphological data mining, three-dimensional modeling and image stitching, registration, editing and annotation. Two independent modalities exist: either XML-based projects, working directly with the file system, or database-based projects, working on top of a local or remote PostgreSQL database. What can you do with it? * Semantic segmentation editor: order segmentations in tree hierarchies, whose template is exportable for reuse in other, comparable projects. * Model, visualize and export 3D. * Work from your laptop on your huge, remote image storage. * Work with an endless number of images, limited only by the hard drive capacity. Dozens of formats supported thanks to LOCI Bioformats and ImageJ. * Import stacks and even entire grids (montages) of images, automatically stitch them together and homogenize their histograms for best montaging quality. * Add layers conveniently. A layer represents, for example, one 50 nm section (for TEM) or a confocal section. Each layer has its own Z coordinate and thickness, and contains images, labels, areas, nodes of 3d skeletons, profiles... * Insert layer sets into layers: so your electron microscopy serial sections can live inside your optical microscopy sections. * Run any ImageJ plugin on any image. * Measure everything: areas, volumes, pixel intensities, etc. using both built-in data structures and segmentation types, and standard ImageJ ROIs. And with double dissectors! * Visualize RGB color channels changing the opacity of each on the fly, non-destructively. * Annotate images non-destructively with floating text labels, which you can rotate/scale on the fly and display in any color. * Montage/register/stitch/blend images manually with transparencies, semiautomatically, or fully automatically within and across sections, with translation, rigid, similarity and affine models with automatically extracted SIFT features. * Correct the lens distortion present in the images, like those generated in transmission electron microscopy. * Add alpha masks to images using ROIs, for example to split images in two or more parts, or to remove the borders of an image or collection of images. * Model neuronal arbors with 3D skeletons (with areas or radiuses), and synapses with connectors. * Undo all steps. And much more... | java, imagej plugin, neuronal circuit, reconstruction, electron microscopy, optical image volume, arbor, synapse, image, align, register, FASEB list |
is listed by: 3DVC is related to: Segmented ssTEM stack of neural tissue is related to: ImageJ has parent organization: University of Zurich; Zurich; Switzerland |
Swiss National Science Foundation 31003A_132969; NINDS 1-R01 NS054814-05 |
PMID:22723842 PMID:20957184 |
If your work uses TrakEM2 or its associated image registration libraries, Please cite. | nlx_151924 | SCR_008954 | SciCrunch Registry | 2026-10-10 12:42:33 | 344 | ||||||
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ICBM 152 Nonlinear atlases version 2009 Resource Report Resource Website 100+ mentions |
ICBM 152 Nonlinear atlases version 2009 (RRID:SCR_008796) | atlas, data or information resource, reference atlas | Unbiased standard magnetic resonance imaging template brain volume for normal population. These volumes were created using data from ICBM project. 6 different templates are available: * ICBM 2009a Nonlinear Symmetric - template which includes T1w,T2w,PDw modalities, also T2 relaxometry (T2 values calculated for each subject using single dual echo PD/T2 scan), and tissue probabilities maps. Also included lobe atlas used for ANIMAL+INSECT segmentation, brain mask, eye mask and face mask. Intensity inhomogeneity was performed using N3 version 1.10.1. * ICBM 2009a Nonlinear Asymmetric template - template which includes T1w,T2w,PDw modalities, and tissue probabilities maps. Intensity inhomogeneity was performed using N3 version 1.10.1. Also included brain mask, eye mask and face mask. * ICBM 2009b Nonlinear Symmetric - template which includes only T1w,T2w and PDw modalities. * ICBM 2009b Nonlinear Asymmetric - template which includes only T1w,T2w and PDw modalities. * ICBM 2009c Nonlinear Symmetric - template which includes T1w,T2w,PDw modalities, and tissue probabilities maps. Also included lobe atlas used for ANIMAL+INSECT segmentation, brain mask, eye mask and face mask. Intensity inhomogeneity was performed using N3 version 1.11. Sampling is different from 2009a template. * ICBM 2009c Nonlinear Asymmetric template - template which includes T1w,T2w,PDw modalities, and tissue probabilities maps. Intensity inhomogeneity was performed using N3 version 1.11 Also included brain mask, eye mask and face mask.Sampling is different from 2009a template. All templates are describing the same anatomy, but sampling is different. Also, different versions of N3 algorithm produces slightly different tissue probability maps. Tools for using these atlases can be found in the Software section. Viewing the multiple atlas volumes online requires Java browser support. You may also download the templates - see licensing information. | magnetic resonance imaging, brain, human, normal |
is related to: MINC/Atlases is related to: bic-mni-models has parent organization: McConnell Brain Imaging Center |
nlx_144297 | SCR_008796 | SciCrunch Registry | , BIC ICBM 152 Nonlinear atlases version 2009 | 2026-10-10 12:42:36 | 278 | |||||||||
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Division of Nutrition, Physical Activity and Obesity Resource Report Resource Website 1+ mentions |
Division of Nutrition, Physical Activity and Obesity (RRID:SCR_008557) | data or information resource, database, organization portal, portal | Our vision a world where regular physical activity, good nutrition, and healthy weight are part of everyone''s life. Our mission to lead strategic public health efforts to prevent and control obesity, chronic disease, and other health conditions though regular physical activity and good nutrition. Our goals: * Increase health-related physical activity through population-based approaches. * Improve those aspects of dietary quality most related to the population burden of chronic disease and unhealthy child development. * Decrease prevalence of obesity through preventing excess weight gain and maintenance of healthy weight loss. Our Work With fiscal year (FY) 2008 funding of 38 million, CDC''s DNPAO is working to reduce obesity and obesity-related diseases. This is done through state programs, research, surveillance, training, intervention development and evaluation, leadership, policy and environmental change, communication and social marketing, and partnership development. See At A Glance 2009 for more. Supporting State Programs The Nutrition, Physical Activity and Obesity Program (NPAO) is a cooperative agreement between the Centers for Disease Control and Prevention''s Division of Nutrition, Physical Activity and Obesity (DNPAO) and 23 state health departments. The program goal is to prevent and control obesity and other chronic diseases through healthful eating and physical activity. The state program will develop strategies to leverage resources and coordinate statewide efforts with multiple partners to address all of the following DNPAO principal target areas: 1. Increase physical activity. 2. Increase the consumption of fruits and vegetables. 3. Decrease the consumption of sugar sweetened beverages. 4. Increase breastfeeding initiation, duration and exclusivity. 5. Reduce the consumption of high energy dense foods. 6. Decrease television viewing. Our Research DNPAO supports research to enhance the effectiveness of physical activity and nutrition programs. Topics of these research activities include: * the effectiveness of parent-focused strategies to reduce the time children spend watching television * the influences of the home environment on sugar-sweetened beverage consumption * the use of policy interventions to promote physical activity * the effectiveness of breastfeeding interventions in various settings. Publications: http://www.cdc.gov/nccdphp/DNPAO/aboutus/manuscripts/index.html | has parent organization: Centers for Disease Control and Prevention | nif-0000-31429 | SCR_008557 | SciCrunch Registry | Division of Nutrition, Physical Activity and Obesity | 2026-10-10 12:42:35 | 1 | ||||||||||
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Brain Computer Interface 2000 Software Package Resource Report Resource Website 100+ mentions |
Brain Computer Interface 2000 Software Package (RRID:SCR_007346) | data processing software, software application, software resource | BCI2000 is a general-purpose system for brain-computer interface (BCI) and adaptive neurotechnology research. It can also be used for data acquisition, stimulus presentation, and brain monitoring applications. The mission of the BCI2000 project is to facilitate research and applications in the areas described. Their vision is that BCI2000 will become a widely used software tool for diverse areas of real-time biosignal processing. In order to achieve this vision, BCI2000 system is available for free for non-profit research and educational purposes. BCI2000 supports a variety of data acquisition systems, brain signals, and study/feedback paradigms. During operation, BCI2000 stores data in a common format (BCI2000 native or GDF), along with all relevant event markers and information about system configuration. BCI2000 also includes several tools for data import/conversion (e.g., a routine to load BCI2000 data files directly into Matlab) and export facilities into ASCII. BCI2000 also facilitates interactions with other software. For example, Matlab scripts can be executed in real-time from within BCI2000, or BCI2000 filters can be compiled to execute as stand-alone programs. Furthermore, a simple network-based interface allows for interactions with external programs written in any programming language. For example, a robotic arm application that is external to BCI2000 may be controlled in real time based on brain signals processed by BCI2000, or BCI2000 may use and store along with brain signals behavioral-based inputs such as eye-tracker coordinates. Because it is based on a framework whose services can support any BCI implementation, the use of BCI2000 provides maximum benefit to comprehensive research programs that operate multiple BCI2000 installations to collect data for a variety of studies. The most important benefits of the system in such situations are: - A Proven Solution - Facilitates Operation of Research Programs - Facilitates Deployment in Multiple Sites - Cross-Platform and Cross-Compiler Compatibility - Open Resource Sponsors: BCI2000 development is sponsored by NIH/NIBIB R01 and NIH/NINDS U24 grants. Keywords: General, Purpose, Systems, Brain, Computer, Interface, Research, Application, Brain, Diverse, Educational, Laboratory, Software, Network, Signals, Behavioral, Eye, Tracker, |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) has parent organization: National Institutes of Health |
NIBIB P41 EB018783; NIBIB R01 EB026439; NINDS U24 NS109103 |
nif-0000-00251 | http://www.nitrc.org/projects/bci2000, http://www.bci2000.org, https://www.neurotechcenter.org/software | SCR_007346 | SciCrunch Registry | BCI2000 | 2026-10-10 12:42:31 | 180 | ||||||||
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Tulane Stem Cell Research and Regenerative Medicine Tissue Culture Core Resource Report Resource Website 1+ mentions |
Tulane Stem Cell Research and Regenerative Medicine Tissue Culture Core (RRID:SCR_007342) | Tulane Tissue Culture Core | biomaterial supply resource, cell repository, material resource | The Stem Cell Research and Regenerative Medicine''s Tissue Culture Core provides cells for research use within the department, as well as for distribution to other facilities. The core obtains hMSCs from bone marrow donor samples and expands these cells for research use. The hMSC''s are also characterized for bone, fat and cartilage differentiation, and are stored on site for use. The Tissue Culture Core also handles the expansion and characterization of mouse and rat MSC''s. The animal cells are cultured in a separate area, and never interact with human derived cells. We also have a supply of hMSC''s marked with GFP+, Mito Red and Mito Blue available. | stem cell, mesenchymal stem cell, marrow stromal cell, frozen, adult, bone marrow, adipose tissue, bone, fat, cartilage |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Tulane University School of Medicine; Louisiana; USA |
United States Department of DefenseBlueprint for Neuroscience Research ; NSF ; NIH |
Public: The Tissue Culture Core provides cells for research use within the department, As well as for distribution to other facilities. | nif-0000-00246 | http://www.som.tulane.edu/gene_therapy/distribute.shtml | SCR_007342 | SciCrunch Registry | Tulane Stem Cell Research Regenerative Medicine Tissue Culture Core | 2026-10-10 12:42:31 | 1 | |||||
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LONI Java Image I/O Plugins Resource Report Resource Website |
LONI Java Image I/O Plugins (RRID:SCR_008277) | data processing software, software application, software resource | Decoders and encoders written in Java for the AFNI, ANALYZE, DICOM, ECAT, GE, MINC, NIFTI and other neuroimaging file formats.The plugins use Java Image I/O interfaces to read and write metadata and image data and can read and write AFNI, ANALYZE 7.5, DICOM, ECAT 7.2, GE 5.0, INTERFILE (including hrrt), MINC, NIFTI, and UCLA PACS file formats. All source code is provided and usage examples are included. | plugin, MRI, software, visualization, data processing |
is related to: Laboratory of Neuro Imaging has parent organization: University of Southern California; Los Angeles; USA |
NIBIB 9P41EB015922-15; NCRR 2-P41-RR-013642-15 |
Available for educational and research purposes only | nif-0000-23320 | SCR_008277 | SciCrunch Registry | 2026-10-10 12:42:32 | 0 | ||||||||
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NIHPD Objective 1 atlases (4.5 - 18.5y) Resource Report Resource Website 10+ mentions |
NIHPD Objective 1 atlases (4.5 - 18.5y) (RRID:SCR_008794) | NIHPD Objective 1 atlases (4.518.5y) | atlas, data or information resource, reference atlas | An unbiased standard magnetic resonance imaging template brain volume for pediatric data from the 4.5 to 18.5y age range. These volumes were created using data from 324 children enrolled in the NIH-funded MRI study of normal brain development (Almli et al., 2007, Evans and Group 2006). Tools for using these atlases can be found in the Software section. To view the atlases online, click on the appropriate JIV2 link in the Download section. You can download templates constructed for different age ranges. For each age range you will get an average T1w, T2w, PDw maps normalized between 0 and 100 and tissue probability maps, with values between 0 and 1. Also each age range includes a binary brain mask. | pediatric, human, mri, brain, child, young human | has parent organization: McConnell Brain Imaging Center | Normal brain development, Aging | PMID:20656036 | nlx_144295 | SCR_008794 | SciCrunch Registry | BIC NIHPD Objective 1 atlases (4.518.5y), McConnell Brain Imaging Center NIHPD Objective 1 atlases (4.518.5y) | 2026-10-10 12:42:33 | 11 | ||||||
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European Centre for the Validation of Alternative Methods Resource Report Resource Website 1+ mentions |
European Centre for the Validation of Alternative Methods (RRID:SCR_008504) | data or information resource, organization portal, portal | ECVAM was created by a Communication from the Commission to the Council and the Parliament in October 1991*, pointing to a requirement in Directive 86/609/EEC** on the protection of animals used for experimental and other scientific purposes, which requires that the Commission and the Member States should actively support the development, validation and acceptance of methods which could reduce, refine or replace the use of laboratory animals: Article 7.2: An experiment shall not be performed if another scientifically satisfactory method of obtaining the result sought, not entailing the use of an animal, is reasonably and practicably available. Article 23: The Commission and Member States should encourage research into the development and validation of alternative techniques which could provide the same level of information as that obtained in experiments using animals, but which involve fewer animals or which entail less painful procedures, and shall take such other steps as they consider appropriate to encourage research in this field. ECVAM has been established in 1992 as a unit of the Environment Institute, part of the Joint Research Centre, and has been transferred to, at that time, newly formed Institute for Health and Consumer Protection in Ispra, Italy in 1998 of which ECVAM is still part of. Duties of ECVAM As defined in the Communication of the European Commission to Council and the European Parliament in October 1991*: 1. To coordinate the validation of alternative test methods at the European Union level. 2. To act as a focal point for the exchange of information on the development of alternative test methods. 3. To set up, maintain and manage a data base on alternative procedures. 4. To promote dialogue between legislators, industries, biomedical scientists, consumer organisations and animal welfare groups, with a view to the development, validation and international recognition of alternative test methods. Moreover, ECVAM should help to expand the JRC''s role in prenormative research. ECVAM thus seeks to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences, through research, new test development and validation, and the establishment of specialised databases, with the aim of contributing to the replacement, reduction and refinement of laboratory animal precedures (in accordance with the 3Rs concept of Russell & Burch***) Due to the political sensitivity of its duties, ECVAM, uniquely at the JRC, has its own Scientific Advisory Committee (ESAC) with participation from all Member States, relevant industrial associations, academic toxicology, the animal welfare movement, as well as other Commission services with interest in the alternatives topic area. The Validation Process Validation is the process by which the reliability and relevance of a procedure are established for a specific purpose. In 1995, based upon experience gained during several recent large-scale validation studies, and in consultation with various international experts (including members of ERGATT), ECVAM published recommendations concerning the practical and logistical aspects of validating alternative test methods (ECVAM workshop report 5). Five main stages in the evolution of new test methods were identified: test development; prevalidation; validation (involving a formal interlaboratory study with the testing of coded chemicals); independent assessment; and progression toward regulatory acceptance. ECVAM has implemented a prevalidation scheme, which includes three main phases: protocol refinement, protocol transfer, and protocol performance. The objective of the prevalidation process is to ensure that any method included in a formal validation study adequately fulfills the criteria defined for inclusion in such a study, so that financial and human resources are used more efficiently, and so that there is a greater likelihood that the expectations of those in the scientific, regulatory and animal welfare communities, who seek the replacement of current animal tests by relevant and reliable alternative methods, will be met. In 2004, ECVAM has published the Modular Approach to the ECVAM Principles on Test Validity (select from the top-menu bar the sector Publications followed by ECVAM Selected Articles) that makes the validation process more flexible, by breaking down the various steps in validation into indipendent modules, and defining for each module the information needed for assessing test validity. Collaborations ECVAMs activities are undertaken in collaboration with numerous laboratories and organisations in the EU Member States, and all over the world. ECVAM also works in close collaboration with other Commission services, such as DG Environment, DG Enterprise, DG Research and DG Health and Consumer Protection. Sponsor. This is a Five years project funded by DG RTD that aims to develop a testing strategy to improve the prediction of oral acute toxicity using non-animals based systems. | nif-0000-30530 | SCR_008504 | SciCrunch Registry | EcVam | 2026-10-10 12:43:30 | 7 | |||||||||||
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Eurobonet Resource Report Resource Website 1+ mentions |
Eurobonet (RRID:SCR_008503) | data or information resource, organization portal, portal | Integration objectives Training and education Standardisation in technology Share of material Web based sharing of information and communication Translational research Spreading excellence objectives Coordinated by Treviso Courses on bone pathology and molecular biology Standard Operation Protocols Web-based discussion forums Research objectives Work packages on: Cartilaginous Tumours (Leiden) Osteogenic Tumours (Munster) Giant Cell Tumours (Oxford) Ewing Sarcoma (Bologna) | nif-0000-30527 | http://www.eurobonet.eu | SCR_008503 | SciCrunch Registry | Eurobonet | 2026-10-10 12:42:32 | 7 | ||||||||||
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Coriell Institute Stem Cell Biobank Resource Report Resource Website |
Coriell Institute Stem Cell Biobank (RRID:SCR_008745) | SCB | biomaterial supply resource, cell repository, material resource | Biospecimen repository that provides scientists with the opportunity to bank their pluripotent stem cell lines and develops in-house induced pluripotent stem cell (iPSC) lines for distribution. They have developed core capabilities to maintain, characterize, bank, and distribute important stem cell resources. The SCB performs extensive identification and characterization testing for all submitted human induced pluripotent stem cell (iPSC) and mouse embryonic stem cell (mES) lines. The identification and quality control measures include karyotype analysis, microsatellite analysis for parental cell line identity matching, sterility testing, and assessment of viability after cryopreservation. Pluripotency characterizations performed by SCB vary depending upon the distributing repository. * NIGMS iPSCs: Surface antigen expression, Embryoid body formation, Pluritest Gene Expression assay * NINDS iPSCs: Surface antigen expression, Embryoid body formation * NIA mES: Surface antigen expression, Embryoid body formation, Transgene induction Each characterized human iPSC line and mES line released for distribution is provided with a Certificate of Analysis, which includes information regarding characterization and quality of the line, images and links to original publications. The human iPSCs distributed by Coriell are strictly for research purposes and cannot be used in human subjects. All terms described in the Material Transfer Agreement (NIGMS and NINDS Repositories) or Assurance Form (NIA Repository) for the stem cell line must be agreed to prior to using stem cell lines from Coriell. | pluripotent stem cell line, stem cell, induced pluripotent stem cell line, cryopreserved, frozen, embryonic stem cell, mouse embryonic stem cell, mouse embryonic stem cell line, biomaterial manufacture |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Coriell Institute for Medical Research |
Aging | Material Transfer Agreement, (NIGMS and NINDS Repositories), Assurance Form (NIA Repository) | nlx_143869 | SCR_008745 | SciCrunch Registry | Stem Cell Biobank | 2026-10-10 12:42:33 | 0 | ||||||
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AutoSeg Resource Report Resource Website 10+ mentions |
AutoSeg (RRID:SCR_009438) | AutoSeg | data processing software, image analysis software, software application, software resource | A novel C++ based application developped at UNC-Chapel Hill that performs automatic brain tissue classification and structural segmentation. AutoSeg is designed for use with human and non-human primate pediatric, adolescent and adult data. AutoSeg uses a BatchMake pipeline script that includes the main steps of the framework entailing N4 bias field correction, rigid registration to a common coordinate image, tissue segmentation, skull-stripping, intensity rescaling, atlas-based registration, subcortical segmentation and lobar parcellation, regional cortical thickness and intensity statistics. AutoSeg allows efficient batch processing and grid computing to process large datasets and provides quality control visualizations via Slicer3 MRML scenes. | analyze, c++, expectation minimization, image-to-image, image-to-template, labeling, linux, macos, microsoft, magnetic resonance, nonlinear warp, nrrd, posix/unix-like, region of interest, registration, resampling, segmentation, spatial transformation, spline interpolation, volumetric analysis, warping, win32 (ms windows), windows, workflow, pediatric, adolescent, adult, young |
is used by: UNC-Wisconsin Neurodevelopment Rhesus MRI Database is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA |
BSD License | nlx_155582 | SCR_009438 | SciCrunch Registry | 2026-10-10 12:43:32 | 24 | ||||||||
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Center for Theoretical Neuroscience; University of Waterloo Resource Report Resource Website |
Center for Theoretical Neuroscience; University of Waterloo (RRID:SCR_008747) | CTN Waterloo | data or information resource, organization portal, portal | The Centre for Theoretical Neuroscience (CTN) was recently established at the University of Waterloo. The Centre is a growing research initiative of the University. The Centre consists of several labs focused on various areas of theoretical neuroscience (aka computational neuroscience). At present, the Centre consists of faculty members from Applied Mathematics, Biology, Psychology, Engineering, Philosophy, Statistics, Computer Science, and their students. The Centre has established a unique Graduate Program in theoretical neuroscience and hosts a regular academic colloquium series. The Centre also hosts the annual public Waterloo Brain Day lectures. The Centre is currently expanding, running searches for additional core faculty. The distinguished faculty of the Centre include two Canada Research Chairs and a fellow of the Royal Society of Canada. In addition, the Centre has a number of student researchers, both graduate and undergraduate, and hosts postdocs and visiting researchers. The Centre also hosts a graduate program for students wishing to obtain an officially recognized specialization in theoretical neuroscience. Faculty at the Centre pursue work on purely theoretical questions regarding the foundational principles guiding the function of neural systems, as well as constructing detailed neurobiological models of specific brain areas. | computational neuroscience | has parent organization: University of Waterloo; Ontario; Canada | nlx_143878 | SCR_008747 | SciCrunch Registry | Centre for Theoretical Neuroscience, CTN | 2026-10-10 12:43:31 | 0 | ||||||||
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BXH/XCEDE Tools Resource Report Resource Website 1+ mentions |
BXH/XCEDE Tools (RRID:SCR_009439) | BXH/XCEDE Tools | data processing software, image analysis software, software application, software resource | A collection of data processing and image analysis tools for data in BXH or XCEDE format. This includes data format encapsulation/conversion, event-related analysis, QA tools, and more. These tools form the basis of the fBIRN QA procedures and are also distributed as part of the fBIRN Data Upload Scripts. | analyze, c, c++, console (text based), dicom, format conversion, linux, macos, mgh/mgz, microsoft, minc, magnetic resonance, nifti, perl, posix/unix-like, quantification, sh/bash, statistical operation, unix shell, windows |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) has parent organization: Function BIRN |
BIRN License | nlx_155583 | SCR_009439 | SciCrunch Registry | 2026-10-10 12:42:37 | 4 |
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