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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://collaborations.gis.a-star.edu.sg/~cmb6/TherMos/
Software used for estimating protein-DNA binding energies from in vivo binding profiles. It is a de novo motif discovery algorithm that exploits the information in transcription factor ChIP-seq or ChIP-exo datasets based on a more natural thermodynamic formalism., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: TherMos (RRID:SCR_002790) Copy
http://cran.r-project.org/web/packages/enviPick/
Software for sequential partitioning, clustering and peak detection of centroided LC-MS mass spectrometry data (.mzXML). Interactive result and raw data plot.
Proper citation: enviPick (RRID:SCR_003059) Copy
http://www.paradigmexperiments.com
Software application for millisecond accurate experimental control for cognitive neuroscience, psychology and linguistics research. Presents text, images, sounds, movies, self-paced reading trials and rating scales. An integrated Python scripting API is available. Joystick and microphone response are available. Supports button boxes from PST, Cedrus, fORP and custom built response boxes. Paradigm can detect fMRI triggers through serial and parallel ports. Includes sample experiments that implement many of the most popular experiment designs., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Paradigm (RRID:SCR_009634) Copy
Database on the sequence of the euchromatic genome of Drosophila melanogaster In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community. Resources * Universal Proteomics Resource: Search for clones for expression and tissue culture * Materials: Request genomic or cDNA clones, library filters or fly stocks * Download Sequence data sets and annotations in fasta or xml format by http or ftp * Publications: Browse or download BDGP papers * Methods: BDGP laboratory protocols and vector maps * Analysis Tools: Search sequences for CRMs, promoters, splice sites, and gene predictions * Apollo: Genome annotation viewer and editor September 15, 2009 Illumina RNA-Seq data from 30 developmental time points of D. melanogaster has been submitted to the Short Read Archive at NCBI as part of the modENCODE project. The data set currently contains 2.2 billion single-end and paired reads and over 201 billion base pairs.
Proper citation: Berkeley Drosophila Genome Project (RRID:SCR_013094) Copy
http://brainhealthregistry.org/
A website aimed at recruiting and assessing subjects for all types of neuroscience studies with the internet. The hope is to accelerate various types of observational studies and clinical trials, and also reduce costs. They are interested in having people, including healthy subjects of all ages, join the registry. Joining only takes a few minutes. The web-based project is designed to speed up cures for Alzheimer's, Parkinson's and other brain disorders. It uses online questionnaires and online neuropsychological tests (which are very much like online brain games).
Proper citation: Brain Health Registry (RRID:SCR_010230) Copy
http://www.pgbovine.net/cde.html
A software application which automatically packages up the code, data, and environment required to deploy and run Linux programs on other machines without any installation or configuration. Users can prepend any set of Linux commands with the "cde" binary, and CDE will run them and automatically package up all files accessed during execution. A package is a directory that can be compressed and delivered to any x86-Linux machine and contains all the files and environment variables required to run the original commands. After receiving the package, the user can run those same commands from within the package on any modern x86-Linux distro., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CDE Tool (RRID:SCR_013981) Copy
Database of all cell lines used in biomedical research which include immortalized cell lines, naturally immortal cell lines (stem cells), widely used and distributed finite life cell lines, vertebrate cell lines (majority being human, mouse, and rat), and invertebrate (insects and ticks) cell lines, as well as cell line synonyms. Each cell line is provided with the following information: the recommended name (the name which appears in the original publication), a list of synonyms, a unique accession number, comments on a number of topics including misspellings and gene transfection, information on the tissue/organ origin with the UBERON code, the NCI Thesaurus or Orphanet ORDO code for the disease(s) the individual suffered from (for cancer and human genetic disease lines only), the species of origin, the parent cell line, cross-references of sister cell lines, the sex of the individual, the category in which the cell line belongs (Adult stem cell; Cancer cell line; Embryonic stem cell; Factor-dependent cell line; Finite cell line; Hybrid cell line; Hybridoma; Induced pluripotent stem cell; Spontaneously immortalized cell line; Stromal cell line; Telomerase immortalized cell line; Transformed cell line; Undefined cell line type), web links, publication references, and/or cross-references to cell line catalogs/collections, ontologies, cell lines databases/resources, and to databases that list cell lines as samples.
Proper citation: Cellosaurus (RRID:SCR_013869) Copy
http://huttenhower.sph.harvard.edu/galaxy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Algorithm for high-dimensional biomarker discovery and explanation that identifies genes, pathways, or taxa characterizing the differences between two or more biological conditions. The algorithm identifies features that are statistically different among biological classes, then performs additional tests to assess whether these differences are consistent with respect to expected biological behavior. Statistical significance and biological relevance are emphasized., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: LEfSe (RRID:SCR_014609) Copy
https://imdevsoftware.wordpress.com/imdev/
A software application of RExcel that integrates R into Excel as an embedded additon for omics tasks and analysis. It can be used specifically for tasks concerning multivariate data visualization, exploration, and analysis. imDev has interactive modules for dimensional reduction, prediction, feature selection, analysis of correlation, and generation of networked structures, all of which provide an integrated environment for systems level analysis of multivariate data.
Proper citation: imDEV (RRID:SCR_014674) Copy
https://github.com/ChristophRau/wMICA
Weighted implementation of Maximal Information Component Analysis, a co-expression network analysis algorithm for analysis of large interconnected networks and the identification of modules of similarly-acting nodes within the larger network.
Proper citation: wMICA (RRID:SCR_015490) Copy
https://neurophysics.ucsd.edu/software.php
Matlab-based routines for the detection and clustering of putative single units from a multi-unit time series, along with quality metrics. This sofwtare was developed by the David Kleinfeld Laboratory at UC San Diego.
Proper citation: UltraMegaSort 2000 (RRID:SCR_015857) Copy
https://sourceforge.net/projects/icacompass/
Algorithm for MATLAB and the EEGLAB toolbox that enables the automatic detection of independent components from an ICA that represent event-related brain potentials. It performs automatic Independent Component (IC) selection with respect to the contributions of the ICs to a certain ERP.
Proper citation: COMPASS (RRID:SCR_015874) Copy
Software that detects kinase-specific phosphorylation sites. GPS provides a platform able to perform its prediction based on a group-based phosphorylation scoring algorithm. It allows users to query multiple protein sequences through a batch prediction mode.
Proper citation: GPS (RRID:SCR_016374) Copy
https://CRAN.R-project.org/package=Boruta
Algorithm that performs feature selection. It finds relevant features by comparing original attributes' importance with importance achievable at random, estimated using their permuted copies (shadows).
Proper citation: Boruta (RRID:SCR_016234) Copy
Database of gene mutation nomenclature.
Proper citation: Nomenclature for the description of sequence variants (RRID:SCR_010261) Copy
http://www.icpsr.umich.edu/icpsrweb/NACDA/Pledge/all.jsp
A data set of cross-nationally comparable microdata samples for 15 Economic Commission for Europe (ECE) countries (Bulgaria, Canada, Czech Republic, Estonia, Finland, Hungary, Italy, Latvia, Lithuania, Romania, Russia, Switzerland, Turkey, UK, USA) based on the 1990 national population and housing censuses in countries of Europe and North America to study the social and economic conditions of older persons. These samples have been designed to allow research on a wide range of issues related to aging, as well as on other social phenomena. A common set of nomenclatures and classifications, derived on the basis of a study of census data comparability in Europe and North America, was adopted as a standard for recoding. This series was formerly called Dynamics of Population Aging in ECE Countries. The recommendations regarding the design and size of the samples drawn from the 1990 round of censuses envisaged: (1) drawing individual-based samples of about one million persons; (2) progressive oversampling with age in order to ensure sufficient representation of various categories of older people; and (3) retaining information on all persons co-residing in the sampled individual''''s dwelling unit. Estonia, Latvia and Lithuania provided the entire population over age 50, while Finland sampled it with progressive over-sampling. Canada, Italy, Russia, Turkey, UK, and the US provided samples that had not been drawn specially for this project, and cover the entire population without over-sampling. Given its wide user base, the US 1990 PUMS was not recoded. Instead, PAU offers mapping modules, which recode the PUMS variables into the project''''s classifications, nomenclatures, and coding schemes. Because of the high sampling density, these data cover various small groups of older people; contain as much geographic detail as possible under each country''''s confidentiality requirements; include more extensive information on housing conditions than many other data sources; and provide information for a number of countries whose data were not accessible until recently. Data Availability: Eight of the fifteen participating countries have signed the standard data release agreement making their data available through NACDA/ICPSR (see links below). Hungary and Switzerland require a clearance to be obtained from their national statistical offices for the use of microdata, however the documents signed between the PAU and these countries include clauses stipulating that, in general, all scholars interested in social research will be granted access. Russia requested that certain provisions for archiving the microdata samples be removed from its data release arrangement. The PAU has an agreement with several British scholars to facilitate access to the 1991 UK data through collaborative arrangements. Statistics Canada and the Italian Institute of statistics (ISTAT) provide access to data from Canada and Italy, respectively. * Dates of Study: 1989-1992 * Study Features: International, Minority Oversamples * Sample Size: Approx. 1 million/country Links: * Bulgaria (1992), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02200 * Czech Republic (1991), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06857 * Estonia (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06780 * Finland (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06797 * Romania (1992), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06900 * Latvia (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02572 * Lithuania (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03952 * Turkey (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03292 * U.S. (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06219
Proper citation: Census Microdata Samples Project (RRID:SCR_008902) Copy
Database that contains gene sets and microRNA-regulated protein-protein interaction networks for longevity, age-related diseases and aging-associated processes.
Proper citation: NetAge Database (RRID:SCR_010224) Copy
http://www.cs.tau.ac.il/~spike/
Database of curated human signaling pathways with an associated interactive software tool for analysis and dynamic visualization of pathways. Individual pathway maps can be viewed and downloaded; the entire database may be browsed, or launched via a map viewer tool that allows dynamic visualization of the database and save networks in XGMML format that can be viewed in all generic XGMML viewers. Map Topics * Cell cycle progress and check points * DNA damage response * Programmed cell death related processes * Stress-activated transcription factors * Mitogen-activated protein kinase pathways * Immune response signaling * HEarSpike: hearing related pathways
Proper citation: SPIKE (RRID:SCR_010466) Copy
A public repository of metabolite information as well as tandem mass spectrometry data is provided to facilitate metabolomics experiments. It contains structures and represents a data management system designed to assist in a broad array of metabolite research and metabolite identification. An annotated list of known metabolites and their mass, chemical formula, and structure are available. Each metabolite is linked to outside resources for further reference and inquiry. MS/MS data is also available on many of the metabolites.
Proper citation: METLIN (RRID:SCR_010500) Copy
Data catalogue, gathered by the Australian Institute of Marine Science (AIMS), a tropical marine research center, on marine science topics including reef weather, sea temperature, cyclones, and water quality.
Proper citation: AIMS Data Centre (RRID:SCR_010475) Copy
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