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http://eagle-i.itmat.upenn.edu/i/00000139-4f55-f0f9-eb5b-b63c80000000

Core facility that provides the following services: Laser confocal microscope access. Penn Dental Medicine houses a Radiance 2100 laser confocal microscope available for use by researchers throughout the School as well as others inside and outside the University.

Proper citation: Penn Laser Confocal Microscope Core (RRID:SCR_009533) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-3502-595e-550e-f59280000000

An Core facility

Proper citation: HSPH Organic Chemistry Laboratory (RRID:SCR_008280) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-e1a0-4fec-d807-77a880000000

The Weld Hill Growth Facilities consist of 12 individually controlled greenhouses and several types of Conviron growth chambers for precise control of growing conditions.

Proper citation: Arnold Arboretum of Harvard University: Weld Hill Growth Facilities (RRID:SCR_009649) Copy   

•   Source: SciCrunch Registry

http://www.itmat.upenn.edu/ctsa/acard/

A core facility in the Center for Pharmacoepidemiology Research and Training created to foster epidemiologic research into therapeutics, using large population-based automated claims databases (Medicaid/Medicare) and medical records databases (GPRD and THIN), and the FDA''s adverse event reporting system (FAERS) database. Goals: * Encourage investigators with diverse training to conduct studies focused on translational therapeutics and drug safety * Provide access to large databases that allow for rapid and cost-effective research on therapeutics and drug safety * Foster collaboration with CTSA sites outside of Penn who wish to use these databases for clinical research

Proper citation: Penn Automated Claims and Medical Record Databases (RRID:SCR_009643) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-357f-dcfa-550e-f59280000000

Equipment access: All new users must be trained by the facility manager over two orientation sessions and be approved to use the equipment in the facility. All users must obtain the financial approval from their PI and financial manager. Please submit a PO number or the Harvard billing code prior to the first use of the facility.

Proper citation: HSPH Molecular Analysis Facility (RRID:SCR_008273) Copy   

•   Source: SciCrunch Registry

http://alaska.eagle-i.net/i/00000130-4c48-c245-67ac-ce7680000000

Core facility that provides the following services: Stable isotope analysis service. The Alaska Stable Isotope Facility is a state-of-the-art laboratory conducting stable isotope analyses of wide range of sample types for researchers from all over Alaska, the USA and the globe. Sample types include organic samples (C, N, O and H isotopes), inorganic samples (e.g. carbonate for C and O) and water (O and H).

Proper citation: UAF Alaska Stable Isotope Facility (RRID:SCR_009556) Copy   

•   Source: SciCrunch Registry

http://hunter-cuny.eagle-i.net/i/00000136-7eb5-5555-949b-425080000000

Core facility that provides the following services: Training Service, TEM Analysis Service. ?The Nanoscale Analytical Facility is equipped with Jeol 2100 EDAX operated at 200kV. Nanomaterial containing samples of inorganic as well as organic building blocks, macromolecular constructs, metallic nanoparticles, metal oxide nano-powders are often imaged.

Proper citation: Hunter Nanoscale Analytical Facility (RRID:SCR_005617) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5977-000a-55da-381e80000000

The Community Practice Research Core (CPRC) provides DF/HCC investigators access to a racially diverse population of over 11,000,000 patients within the community-based clinical practices of Harvard Vanguard Medical Associates (HVMA)/ Atrius Health, a Boston-based medical specialty group comprised of over 20 office locations across eastern Massachusetts providing care to more than 510,000 adult and pediatric patients; Harvard Pilgrim Health Care (HPHC), one of the largest health maintenance organizations in New England with close to 1,000,000 members and an extensive provider network that includes physicians who practice in a variety of settings; the Cancer Research Network is comprised of 9 health care systems and 6 affiliate sites across the nation with a total membership of 11,000,000 patients. The populations of HVMA/Atrius, HPHC, and the CRN are particularly ideal for studies: (1) involving basic, clinical, and population sciences; (2) addressing diverse communities; (3) investigating dissemination of proven technologies and interventions; (4) requiring large samples of patients and/or providers; (5) involving rare cancers; and (6) of cancer prevention.

Proper citation: DF/HCC Community Practice Research Core (RRID:SCR_009735) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5d8c-a118-55da-381e80000000

Core provides all of the tools of modern functional proteomics. Equipped with technologies for proteomics; protein profiling, protein identification, protein and peptide fractionation, and quantization. Personalized experimental design consultation, comprehensive individualized bioinformatics support. The mission of the DF/HCC Cancer Proteomics Core is to develop a comprehensive and interdisciplinary proteomics core for High Sensitivity, High Resolution and High Throughput Proteomics with particular emphasis on in depth proteomic consultation, referral to the optimal proteomics facility and a strong focus on clinical sample analysis. The core combines consultation, service and education into a comprehensive, translationally and clinically oriented proteomics core.

Proper citation: Dana Farber and Harvard Cancer Center Cancer Proteomics Center (RRID:SCR_009733) Copy   

•   Source: SciCrunch Registry

http://ccny-cuny.eagle-i.net/i/00000137-4cd7-8ff5-bb24-040880000000

Basic research equipment for RCMI Faculty

Proper citation: CCNY RCMI Core Facility (RRID:SCR_009698) Copy   

•   Source: SciCrunch Registry

http://ccny-cuny.eagle-i.net/i/00000137-4cd8-9a02-bb24-040880000000

The microscopy center is a shared central facility whose primary goal is to promote scientific research by providing training in basic operation of the scanning electron microscope (SEM), the transmission electron microscope (TEM) and the Confocal.RRRRR RRRRR New users of the facility are asked to submit an application then schedule an appointment with the manager to discuss the project or to begin training.

Proper citation: CCNY Microscopy Facility (RRID:SCR_009697) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-9d60-89cb-b977-103480000000

Core facility that provides the following services: Scientific computing for data analysis and scientific graphics, Advice and consultation regarding grant applications and management of clinical trials data, Training in study design, data collection, computerization, and statistical methods.

The Biostatistics Core facility is a shared resource supporting consultation on biostatistics and epidemiology throughout the Dana-Farber/Harvard Cancer Center (DF/HCC). The mission of the core is to ensure that experimental designs, study monitoring and data analyses take advantage of robust, efficient methods that reflect ''best practices'' in biostatistics and epidemiology; to support NIH-funded peer reviewed grants that do not contain salary support for statisticians; and to enable pilot and small scale studies to become part of successful applications for peer-reviewed funding. These services are available to Dana-Farber / Harvard Cancer Center members only. The Biostatistics Core is located across several of the member institutions of the DF/HCC. To contact the Core, please email or call the statistician associated with your disease site.

Proper citation: DF/HCC Biostatistics Core Facility (RRID:SCR_009730) Copy   

•   Source: SciCrunch Registry

http://cau.eagle-i.net/i/00000135-ab9d-72b3-ecf8-187780000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core provides next generation sequencing service. Collaborative effort between the CCRTD and the Ovarian Cancer Institute at Georgia Tech University (OCIGT). CCRTD provides laboratory to prepare libraries and to operate the instrument, while OCIGT contributes bioinformatics support for processing the data and additional services to complement genomics data including hardware, software, and personnel. OCIGT contributes patients sample procurement and complementary technologies including Affymetrix microarray technology and mass spectroscopy analysis.

Proper citation: Clark Atlanta University Collaborative Center for Cancer Genomics and Bioinformatics Core Facility (RRID:SCR_009695) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-6e00-af62-55da-381e80000000

Core facility that provides the following services: DNA analysis - Affymetrix GeneChip arrays service, DNA analysis - Illumina infinium whole genome genotyping service, DNA analysis - custom content genotyping service, RNA Analysis - Affymetrix gene expression service, RNA Analysis - Illumina Gene Expression service, RNA Analysis - Illumina whole-genome DASL service. The Genetic Analysis Platform collaborates with scientists at the Broad and across the world to identify and characterize patterns of genetic variation and gene expression. These patterns can yield a deeper understanding of how genetic factors influence disease risk and treatment outcomes in a wide range of human diseases, including type 2 diabetes, Crohn''s disease, schizophrenia, and cancer, among many others. Over the past several years, the platform has been a leading contributor to major projects such as the International Haplotype Map Project, The Cancer Genome Atlas, the 1,000 Genomes Project, the Genes and Environment Initiative, and served as a national genotyping center under a NIH/NCRR program. Genetic Analysis Platform (GAP) scientists are experts in a wide range of genomic technologies and technology platforms, including genotyping, gene expression and directed resequencing, and routinely apply these technologies to studies of both human and non-human samples. In addition, teams of platform researchers work to test out emerging genetic technologies, develop informatics tools and infrastructure to enhance scientific research, and coordinate large-scale projects involving collaborators both within and beyond the Broad.

Proper citation: Broad Genetic Analysis Platform (RRID:SCR_009690) Copy   

•   Source: SciCrunch Registry

http://cau.eagle-i.net/i/00000135-abea-80e6-ecf8-187780000000

In CCRTD, we provide excellent support for Cell Biology research and advanced cell visualization applications. We have complete facilities for cell growth, handling, and storage. Cell Culture Facility maintains Cell Storage Cryo Tanks with uninterruptable liquid nitrogen supply and two separate Cell Culture rooms fully equipped with eight temperature and CO2-controlled Cell Growth Incubators, two Biological Safety Cabinets, Fluorescence-Activated Cell Sorter (FACS), two late model Inverted Digitized Microscope (Zeiss), one of which is fluorescence-enabled and possesses Z-stacking and live cell imaging capabilities, automated Cell Counter (Nexcelom Bioscience), and refrigerated storage for media and cell culture reagents.

Proper citation: CAU CCRTD-Cell Biology (RRID:SCR_009691) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-4506-110d-eb5b-b63c80000000

Core facility that provides the following services: Stem cell differentiation, Stem cell line propagation. The human embryonic stem cell/induced pluripotent Stem Cell (hESC/iPSC) Core generates control and patient-specific iPSC lines by cellular reprogramming using current technologies. The core has a training course in cell maintenance and growth, specialized differentiation protocols for disease modeling and drug screening, and quality-control reagents for the Children?s Hospital and University of Pennsylvania academic communities. The facility maintains five NIH-approved human ESC lines and has generated more than 60 disease-specific iPSC lines.

Proper citation: CHOP Human Embryonic stem cell/induced pluripotent stem cell Core (RRID:SCR_009727) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-60a7-d769-c437-ff0b80000000

The BWH-BRI Antibody Core Facility provides high quality, purified monoclonal antibodies to the BWH research community. Because the antibodies are made in-house and require no shipping, they are available at a cost substantially lower than that of commercial vendors. Antibodies are of standardized quality and are available in two convenient aliquots: 500ugs and 10mgs. The Core maintains an inventory of commonly used antibodies, which allows orders to be filled quickly.

Proper citation: BWH-BRI Antibody Core Facility (RRID:SCR_009689) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7cbe-8ce9-fbab-3b8480000000

Core facility that provides the following services: Vascular laboratory services, Vascular laboratory service, Carotid intima medial thickness measurment (IMT), Vascular laboratory service, Brachial Artery Reactivity (BART), Echocardiographic laboratory services, Exercise physiology laboratory services, Vascular laboratory service, Continuous arterial spin-labeling perfusion magnetic resonance imaging. The Cardiovascular Core provides cardiac testing services for children. The Core provides the technical services and expertise to conduct the highest quality research, provides research tests in a cost-effective manner, and provides unparalleled training opportunities in clinical research for investigators, fellows, students and technicians.

Proper citation: CHOP CTRC Cardiovascular Imaging Core (RRID:SCR_009722) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2511-e97c-5617-794280000000

Core facility that provides the following services: ES cell transfection (electroporation), Thawing/expansion of targeted ES cells, Microinjection of ES cells into blastocysts, Microinjection of DNA constructs into egg pronuclei for generating transgenic mice, Microinjection of BAC DNAs, DNA injection and microdissection, Lentiviral transgenics service, Injection of induced pluripotent stem cells for testing totipotency, Tail biopsy service, Breeding services, Mouse manipulation consultation. The Brigham & Women''s Hospital Transgenic Core Facility provides services for generating transgenic and knockout mice. Established in 1992, the BWH Core Facility has been providing gene targeting and microinjection services using state-of-the-art facilities and equipment. Dr. Lina Du, formerly a plastic surgeon in Beijing and an expert in microvascular surgery, performs both blastocyst and pronuclear injections. She has over 15 years of experience in embryo manipulation and the generation transgenic mice. The Core Facility has all of the equipment necessary for generation of transgenic mice including a Nikon Diaphot microscope equipped with Nomarski Optics and Narishige micromanipulators for microinjections, Nikon surgical microscopes for egg isolation ad transfer, a sutter needle puller and a de Fonbrune microforge. The facility maintains mice necessary for egg donors, egg recipients, and vasectomized males. This is a non-profit facility and charges are based upon anticipated mouse costs, maintenance of mice and equipment, and purchase of necessary surgical supplies and chemicals. The ES cell culture service has been offered for 6 years. Our staff carries out electroporation of targeting vectors into ES cells and provides investigators with DNA to identify ES cells carrying the desired recombination events. Then they expand the appropriate ES Cells for microinjection into blastocysts by the BWH Transgenic Core.

Proper citation: BWH Transgenic Core Facility (RRID:SCR_009688) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-4fa9-b5b5-eb5b-b63c80000000

Core facility that provides the following services: Development of assessment methods for pediatric psychological, neuropsychological, and psychiatric research, Intervention development and implementation. The Behavioral Neurosciences Core provides consultation and assistance to investigators regarding psychological, neuropsychological, and psychiatric components of research studies involving pediatric subjects. Together, the services provided by the Behavioral Neurosciences Core offer research infrastructure support across the entire process of research, from pre-design consultation to development and analysis of behavioral data, and across multiple domains of functioning and outcomes.

Proper citation: CHOP CTRC Behavioral Neurosciences Core (RRID:SCR_009721) Copy   

•   Source: SciCrunch Registry