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http://experimentalman.com/blog/
Blog about how leading-edge bio-science and technology is impacting individuals and society. This blog is an outgrowth of David Ewing Duncan''s new book, Experimental Man: What one mans body reveals about youy future, your health, and our toxic world. In the book he reports taking over 250 tests in the realms of genes, environment, brain and body and explore what these tests can tell us about one persons health, past, present, and future.
Proper citation: Experimental Man Blog (RRID:SCR_008378) Copy
Purpose of the Myc Hubsite The emergence of complex DNA microarray data on gene expression creates vast new opportunities but also poses serious challenges for information and library sciences. This complexity becomes more challenging as certain genes, such as MYC that encodes a transcription factor, switch on other genes. The purpose of this website is to provide a hub for the integration of information on Myc target genes, the role of Myc in human cancers, and proteins that interact with the Myc transcription factors. Links are provided that connect to PUBMED citations, Unigene database, and in specific cases to original data. Sponsor: Funded by a grant from the National Library of Medicine
Proper citation: MYC Cancer Gene (RRID:SCR_008608) Copy
http://www.nitrc.org/projects/jist/
A native Java-based imaging processing environment similar to the ITK/VTK paradigm. Initially developed as an extension to MIPAV (CIT, NIH, Bethesda, MD), the JIST processing infrastructure provides automated GUI generation for application plug-ins, graphical layout tools, and command line interfaces. This repository maintains the current multi-institutional JIST development tree and is recommended for public use and extension. JIST was originally developed at IACL and MedIC (Johns Hopkins University) and is now also supported by MASI (Vanderbilt University).
Proper citation: JIST: Java Image Science Toolkit (RRID:SCR_008887) Copy
It was created to serve as a gateway to alternatives news, information, and resources on the Internet and beyond. Altweb now is the U.S. home of the journal ALTEX: Alternatives to Animal Experimentation, which is the official publication of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). Altweb is intended to serve: *Biomedical researchers *Industry *The international alternatives community *The international regulatory community(ies) *IACUCs and other institutional groups that review animal protocols *The animal welfare community *Individuals and groups who work with laboratory animals (technicians, veterinarians, etc.) *Educators *Students *The general public Altweb has five practical goals: 1. To assist scientists and others seeking to conduct a search for alternatives methods. 2. To serve as a CRPcentral reference pointfor alternatives information, publications, databases, calendars, and other resources. 3. To support the creation and maintenance of new alternative resources as needed, when no other organization can/will do so. 4. To promote the use of alternatives resources by publicizing them on the site and through e-mail or other outreach. 5. To facilitate communication and collaboration among members of the alternatives community, in particular those who work in database or information management.
Proper citation: Atlweb: Alternatives to Animal Testing (RRID:SCR_007265) Copy
Center for Computational Biology as a joint research center in the McKusick-Nathans Institute of Genetic Medicine, spanning the School of Medicine, the Whiting School of Engineering, the Bloomberg School of Public Health, and the Krieger School of Arts & Sciences. Multidisciplinary center dedicated to research on genomics, genetics, DNA sequencing technology, and computational methods for DNA and RNA sequence analysis.
Proper citation: Center for Computational Biology at JHU (RRID:SCR_016680) Copy
http://psychiatry.igm.jhmi.edu/SynaptomeDB/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Ontology-based knowledgebase for synaptic genes. These genes encode components of the synapse including neurotransmitters and their receptors, adhesion / cytoskeletal proteins, scaffold proteins, transporters, and others. It integrates various and complex data sources for synaptic genes and proteins., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: SynaptomeDB (RRID:SCR_000157) Copy
http://www.nitrc.org/projects/longitudinal_ms/
The Longitudinal MS Lesion Imaging Archive provides Training data consisting of longitudinal images from five patients and Testing data consisting of 15 patients. Each longitudinal dataset includes T1-weighted, T2-weighted, PD-weighted, and T2-weighted FLAIR MRI with 3-5 time points acquired on a 3T MR scanner. T1-weighted images have approximately a 1mm cubic voxel resolution, while the other scans are 1mm in plane with 3mm sections. Accounting for the multiple time points, this constitutes approximately 80 individual data sets. The Training data contains manual segmentations of the MS lesions from two different raters for each of the time points provided.
Proper citation: Longitudinal MS Lesion Imaging Archive (RRID:SCR_014136) Copy
http://ls-snp.icm.jhu.edu/ls-snp-pdb/
A web tool for genome-wide annotation of human SNPs.
Proper citation: LS-SNP/PDB (RRID:SCR_010774) Copy
http://www.nitrc.org/projects/jhucis_pedatlas/
Anatomical atlases constructed by Computational Anatomy of Johns Hopkins University for analysis of shape vectors. The atlases were generated from segmented hippocampal and amygdala structures in acquired populations of children, adolescents and young adults in neuroimaging studies of major depression disorder (MDD) at Washington University at St Louis.
Proper citation: Atlases of amygdala and hippocampus for pediatric populations (RRID:SCR_014085) Copy
http://www.scienceexchange.com/facilities/deep-sequencing-and-microarray-core
Our aim is to provide cost-effective and time-efficient access to cutting-edge genomic technologies and expert assistance with experimental design and data analysis.
Proper citation: JHU Deep Sequencing and Microarray Core (RRID:SCR_011045) Copy
Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.
Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy
Interactive Python based interface to Rosetta molecular modeling suite. Stand alone Python based implementation of Rosetta molecular modeling package that allows users to write custom structure prediction and design algorithms using major Rosetta sampling and scoring functions.
Proper citation: PyRosetta (RRID:SCR_018541) Copy
http://ccb.jhu.edu/software/glimmerhmm/
A gene finder based on a Generalized Hidden Markov Model (GHMM). Although the gene finder conforms to the overall mathematical framework of a GHMM, additionally it incorporates splice site models adapted from the GeneSplicer program and a decision tree adapted from GlimmerM. It also utilizes Interpolated Markov Models for the coding and noncoding models . Currently, GlimmerHMM's GHMM structure includes introns of each phase, intergenic regions, and four types of exons (initial, internal, final, and single).
Proper citation: GlimmerHMM (RRID:SCR_002654) Copy
http://www.mri-resource.kennedykrieger.org/
Biomedical technology research center that provides expertise for the design of quantitative magnetic resonance imaging (MRI) and spectroscopy (MRS) data acquisition and processing technologies that facilitate the biomedical research of a large community of clinicians and neuroscientists in Maryland and throughout the USA. These methods allow noninvasive assessment of changes in brain anatomy as well as in tissue metabolite levels, physiology, and brain functioning while the brain is changing size during early development and during neurodegeneration, i.e. the changing brain throughout the life span. The Kirby Center has 3 Tesla and 7 Tesla state of the art scanners equipped with parallel imaging (8, 16, and 32-channel receive coils) and multi-transmit capabilities. CIS has an IBM supercomputer that is part of a national supercomputing infrastructure. Resources fall into the following categories: * MRI facilities, image acquisition, and processing * Computing facilities and image analysis * Novel statistical methods for functional brain imaging * Translating laboratory discoveries to patient treatment
Proper citation: National Resource for Quantitative Functional MRI (RRID:SCR_006716) Copy
BRAIN Initiative data archive for multi-modal neurophysiological and behavioral data, supporting the Brain Behavior Quantification and Synchronization (BBQS) Program. Accessible and versatile data archive for storage, processing, and curation of multimodal neurophysiological and behavioral datasets. EMBER extends established BRAIN Initiative data infrastructure, provides new data harmonization and synchronization capabilities, and supports scalable integrations for data coordination and AI driven batch processing to enable the goals of the BBQS program.
Proper citation: Ecosystem for Multi-modal Brain-behavior Experimentation and Research (RRID:SCR_026700) Copy
http://www.humanproteinpedia.org/
A community portal for sharing and integration of human protein data that allows research laboratories to contribute and maintain protein annotations. The Human Protein Reference Database (HPRD) integrates data that is deposited along with the existing literature curated information in the context of an individual protein. Data pertaining to post-translational modifications, protein-protein interactions, tissue expression, expression in cell lines, subcellular localization and enzyme substrate relationships can be submitted.
Proper citation: Human Proteinpedia (RRID:SCR_002948) Copy
This center provides routine behavioral/cognitive testing of mice with phenotypes that are expressed as a consequence of alterations at the level of gene function, and that are relevant to basic neuroscience and to animal models of neurological and psychiatric disorders. Current Research Behavioral testing within the center involves a collaborative component in which mice provided by users are assessed for behavioral/cognitive functions. All research includes behavioral assessment of a variety of genetically altered mice provided by users. Services Provided The objective of the center is to provide a link between genetic and molecular analysis of neural function and the study of integrative systems and clinical conditions through behavioral assessment of animal models, and mouse behavioral phenotypes generated by genetic modification. Sponsors: This resource is supported by the National Center of Research Resources (Grant Number: P40 RR017688).
Proper citation: Neurogenetics and Behavior Center (RRID:SCR_002851) Copy
http://www.hopkinsmedicine.org/som/
Johns Hopkins University School of Medicine is a medical graduate institution that provides physician, clinical fellowship and residency programs.
Proper citation: Johns Hopkins University School of Medicine; Baltimore, Maryland; USA (RRID:SCR_000973) Copy
http://ccb.jhu.edu/software/sim4cc/
Software tool as cross species spliced alignment program.Heuristic sequence alignment tool for comparing cDNA sequence with genomic sequence containing homolog of gene in another species.
Proper citation: sim4cc (RRID:SCR_001204) Copy
Infrastructure for sharing cardiovascular data and data analysis tools. Human ExVivo heart data set and canine ExVivo normal and failing heart data sets are available. Canine hearts atlas and human InVivo atlases are available.
Proper citation: CardioVascular Research Grid (CVRG) (RRID:SCR_004472) Copy
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