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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.norch.org/metabolic-phenotyping-core/
Core that provides NORCH investigators with access to model creation and detailed metabolic phenotyping. Its services include: model generation, including genomic targeting and production of metabolically relevant cell types; metabolic characterization of patient-derived, user-provided, or model generated samples; consultation on model development and metabolic characterization projects; and training for Core techniques in model generation and detailed metabolic characterization.
Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Phenotyping Core (RRID:SCR_015429) Copy
http://www.norch.org/metabolic-imaging-core/
Core that links a variety of imaging facilities providing services to NORCH investigators who currently require or plan to conduct human studies using imaging research instrumentation and expertise. Its goal is to provide users with access to imaging technology for in-vivo phenotyping of human tissues for nutrition, obesity and metabolism studies.
Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Imaging Core (RRID:SCR_015426) Copy
https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core
Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.
Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=30
Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure.
Proper citation: MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) Copy
https://nyonrc.cumc.columbia.edu/content/animal-phenotyping-core
Core that allows investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. Its services range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue.
Proper citation: New York Obesity Nutrition Research Center Animal Phenotyping Core (RRID:SCR_015414) Copy
http://sph.unc.edu/norc/animal/
Core that offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease. It provides access to methods, equipment, and populations to support high quality and high throughput phenotyping of energy balance components in mice.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Animal Metabolism Phenotyping Core (RRID:SCR_015465) Copy
http://depts.washington.edu/uwnorc/core-facilities/energy-balance-core/
Core that provides affiliated investigators with a resource for measuring energy balance and body composition in rodent models, and for applying neuroscience techniques to nutrition and obesity-related research.
Proper citation: University of Washington Nutrition and Obesity Research Center Energy Balance Core (RRID:SCR_015469) Copy
http://www.norc.uab.edu/corefacilities/animalmodels
Core that provides specialized expertise in the use of animal models and instrumentation to facilitate animal research related to nutrition and obesity.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core (RRID:SCR_015466) Copy
Core that uses technologies to facilitate the translation of traditional evidence-based behavioral interventions into effective web- and mobile-based interventions in fields such as obesity and cancer prevention.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Communication for Health Applications and Interventions Core (RRID:SCR_015461) Copy
http://mmoc.med.umich.edu/CoreIntegrativeBiostatisticsInformatics.php
Core facility whose services include expertise in experimental design and modeling for preclinical, clinical and translational research studies that integrate clinical, molecular, neurobehavioral and other phenotype data. It also offers support for data acquisition and analysis by the MMOC phenotyping Cores and Investigational Weight Management Clinic, expertise in database construction, maintenance and security relevant to investigators studies, and development and use of database and software tools for information organization and visualization of tightly-linked multiscale data for T1 translation of research knowledge relevant to obesity.
Proper citation: University of Michigan Nutrition and Obesity Research Center Integrative Biostatistics and Informatics Core (RRID:SCR_015478) Copy
http://depts.washington.edu/uwnorc/core-facilities/administrative-and-enrichment-core/
Core that is responsible for the overall administrative coordination of the NORC. It also administers the Biostatistics Subcore, Pilot and Feasibility Program, and Enrichment Seminar Series.
Proper citation: University of Washington Nutrition and Obesity Research Center Administrative and Enrichment Core (RRID:SCR_015471) Copy
http://depts.washington.edu/uwnorc/core-facilities/analytic-core/
Core that provides affiliated investigators with access to nutritional assays, new methods development, and consultation services. Services also include quantitative measures of nitrogen-containing compounds, carbohydrates and related compounds, lipids and related compounds, and more.
Proper citation: University of Washington Nutrition and Obesity Research Center Analytic Core (RRID:SCR_015470) Copy
http://depts.washington.edu/uwnorc/core-facilities/adipose-tissue-and-obesity-core/
Core that provides affiliated investigators with assistance for in vivo and in vitro studies in both subcutaneous and visceral human adipose tissue. Body and liver fat measurement by DXA and MRI are also provided, as is support for translational studies that assist investigators in the design conduct of clinical obesity research.
Proper citation: University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core (RRID:SCR_015481) Copy
A cell repository containing cells and DNA for studies of aging and the degenerative processes associated with it. Scientists use the highly-characterized, viable, and contaminant-free cell cultures from this collection for research on such diseases as Alzheimer's disease, progeria, Parkinson's disease, Werner syndrome, and Cockayne syndrome. The collections of the Repository include DNA and cell cultures from individuals with premature aging disorders, as well as DNA from individuals of advanced age from the the Baltimore Longitudinal Study of Aging at the Gerontology Research Center and other Longevity Collections. The Repository also includes samples from an Adolescent Study of Obesity, Apparently Healthy Controls, Animal Models of Aging, and both human and animal differentiated cell types. The cells in this resource have been collected over the past three decades using strict diagnostic criteria and banked under the highest quality standards of cell culture. Scientists can use the highly-characterized, viable, and contaminant-free cell cultures from this collection for genetic and cell biology research.
Proper citation: Aging Cell Repository (RRID:SCR_007320) Copy
http://coordinatingcenter.ucsf.edu/pride/
Randomized controlled trial being conducted at two clinical centers in the United States to learn more about the effects of weight loss on urinary incontinence. About 330 overweight women aged 30 or older will participate and will be followed for 18 months. Efficacy of weight reduction as a treatment for urinary incontinence will be examined at 6 months following the intensive weight control program, and the sustained impact of the intervention will be examined at 18 months. To increase the maintenance of weight reduction and facilitate evaluation of the enduring impact of weight loss on urinary incontinence, they propose to study a motivation-based weight maintenance program. At the end of the intensive weight control program, women randomized to the weight loss program will be randomized to either a 12-month skill-based maintenance intervention or to a motivation-based maintenance intervention. The maintenance interventions maximize the potential for sustained weight loss and will allow them to determine if long-term weight reduction will produce continued improvement in urinary incontinence.
Proper citation: Program to Reduce Incontinence by Diet and Exercise (RRID:SCR_009018) Copy
http://rc2resource.scripps.edu
Database portal for a project that aims to discover and characterize new molecular pathways that can be targeted pharmacologically to revert obesity-linked adipocyte defects that drive systemic insulin resistance and type 2 diabetes. It works to identify in tandem physiologically-relevant proteins and chemical tools in order to expedite their functional annotation and therapeutic validation.
Proper citation: Chemoproteomic identification and therapeutic validation of proteins of metabolic significance (RRID:SCR_015847) Copy
http://www.geisinger.org/research/centers_departments/genomics/mycode/mycode.html
By collecting and analyzing blood samples from Geisinger''s large patient population, MyCode will help unlock the mysteries of some of the most devastating and debilitating diseases. Blood samples are obtained from patients of certain Geisinger specialty clinics to study specific conditions, such as obesity and cardiovascular disease, and also from patients of Geisinger primary care clinics to provide a representative sample of the regional population. More than 60,000 samples from over 23,000 Geisinger patients have been collected so far, and sample collection is ongoing. MyCode researchers use the blood samples to study the genetic causes of diseases and certain disease-related molecular mediators. Knowledge gained from these studies will allow researchers to pursue innovative approaches to disease prevention, diagnosis and treatment. To be of value for Genomic Medicine research, bio-banked samples must be connected to clinical data: MyCode allows genetic and molecular data about the samples to be connected to medical data in a way that protects patient identity. When a patient agrees to participate in MyCode, blood samples for the MyCode Project are collected during blood draws ordered as part of the patient''s routine medical care. After the sample is drawn and labeled, a staff member from the Weis Center for Research transports the blood to the Geisinger Clinic Genomics Core (GCGC) where it is processed for storage. At this stage, all personal identification markers are removed and the samples are assigned a randomly-selected identification number. A secure key is maintained that allows approved researchers to connect the samples to the clinical data for genomic studies in a way that ensures confidentiality of the information. To maintain confidentiality of MyCode data the code linking the research numbers and the electronic health records are kept in a password-protected files accessible only to MyCode team members. Additionally, all results generated from the samples are reported as a group so that individuals are not identified. The samples are stored indefinitely.
Proper citation: Geisinger Biobank (RRID:SCR_005652) Copy
Medical technology company that develops and manufactures devices and therapies to treat more than 30 chronic diseases, including heart failure, Parkinson's disease, urinary incontinence, Down syndrome, obesity, chronic pain, spinal disorders, and diabetes. A Commercial healthcare organization for both patients and healthcare professionals. For professionals, it provides products, therapy and procedure solutions, and services.
Proper citation: Medtronic (RRID:SCR_003988) Copy
https://www.signalingpathways.org/ominer/query.jsf
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on February 25, 2022.Software tool as knowledge environment resource that accrues, develops, and communicates information that advances understanding of structure, function, and role in disease of nuclear receptors (NRs) and coregulators. It specifically seeks to elucidate roles played by NRs and coregulators in metabolism and development of metabolic disorders. Includes large validated data sets, access to reagents, new findings, library of annotated prior publications in field, and journal covering reviews and techniques.As of March 20, 2020, NURSA is succeeded by the Signaling Pathways Project (SPP).
Proper citation: Nuclear Receptor Signaling Atlas (RRID:SCR_003287) Copy
Brings together Centers for Disease Control and Prevention, National Institutes of Health, Robert Wood Johnson Foundation, and U.S. Department of Agriculture to accelerate progress in reducing childhood obesity in America, to manage projects and reach common goals, to coordinate funding to make the most of available resources, to share insights and expertise to strengthen research. NCCOR focuses on efforts that have to benefit children, teens, and their families, and communities in which they live.
Proper citation: National Collaborative on Childhood Obesity Research (RRID:SCR_019150) Copy
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