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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | ||||||||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource (RRID:SCR_015291) | access service resource, core facility, resource, service resource | Core facility that provides clinical applications and methods to make kidney research translational and applicable to care settings. | pkd, polycystic kidney disease, clinical research, translational research |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015291 | SciCrunch Registry | 2026-10-10 12:46:59 | 0 | ||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core (RRID:SCR_015318) | access service resource, core facility, resource, service resource | Core which supports the work of the Baltimore Polycystic Kidney Disease research center by providing antibody validation services and vectors to researchers. | pkd, polycystic kidney disease, antibody validation |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community, Fee for service | SCR_015318 | SciCrunch Registry | 2026-10-10 12:46:10 | 0 | ||||||||
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Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease Resource Report Resource Website 1+ mentions |
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (RRID:SCR_000690) | CRISP | clinical trial, resource | A five-year prospective cohort study following 240 patients who have autosomal-dominant polycystic kidney disease (PKD) to determine whether changes in anatomic characteristics of their kidneys as measured by magnetic resonance imaging will be useful in providing surrogate measures for disease progression. CRISP's overall goal is to develop methods that would facilitate shortening the observation period necessary to determine efficacy of treatment interventions in PKD patients. Specific goals of this study are to: * Quantify cyst growth and ascertain severity of renal parenchymal involvement by sequential measurement of total kidney volume and the ratio of intact parenchyma to renal parenchyma occupied by cysts over time * Establish useful clinical correlations of imaging data with other markers of disease progression * Identify and test other potential markers or indices of disease progression, for example, assessment of loss of heterozygosity of renal cells shed in the urine, or other markers, in cohorts of patients with PKD * Gain information about the cost-effectiveness, patient acceptability, and advantages and disadvantages of different imaging techniques used serially in patients with PKD. Some experience has been gained in establishing that repeat imaging of the same PKD patient, using these techniques, yields reproducible estimates of kidney size and the proportion of renal parenchyma occupied by cysts. MRI may also have the advantage of permitting simultaneous estimation of GFR. Ultrasound has the advantage of being more cost-effective and perhaps more acceptable to patients for repetitive studies, but the measurements may be less accurate and reproducible. Nonetheless, there is very limited experience in applying these techniques to follow progression of the renal disease. Development of improved, reproducible imaging methods that assess cyst growth and provide markers of disease progression could markedly improve the feasibility of clinical trials. Participating clinical centers are Emory University, the Mayo Clinic, University of Kansas, and the University of Alabama at Birmingham. The data coordinating and imaging analysis center is at Washington University. (PI has since moved to University of Pittsburgh) The study found that kidney enlargement resulting from the expansion of cysts is continuous, quantifiable, and associated with the decline of renal function. Cystic expansion occurs at a consistent rate per individual, although it is heterogeneous in the population, and that larger kidneys are associated with more rapid decrease in renal function. These anatomic characteristics of patient kidneys may provide useful surrogate measures for disease progression, and hence enhance the development of targeted therapies for autosomal dominant PKD. CRISP III is a five-year prospective cohort study to follow ~170 remaining autosomal dominant polycystic kidney disease (ADPKD) patients who were part of the original CRISP cohort study. CRISP III will verify and extend the preliminary observations of CRISP to determine the extent to which quantitative (kidney volume and blood flow, and hepatic and kidney cyst volume) or qualitative (cyst distribution and character) structural parameters predict renal insufficiency and develop and test new metrics to quantify and monitor disease progression. Urine metabolites and the genome will be correlated with the progression of disease to look for new, predictive disease biomarkers. This information from CRISP III will help determine if the kidney enlargement, blood flow, cyst distribution, or urine metabolites can function as an informative surrogate measure for disease progression. | mri, kidney volume, cyst volume, kidney, renal function, disease progression, measure, blood flow, hepatic cyst volume, kidney cyst volume, renal insufficiency, urine metabolite, surrogate measure, clinical, intervention |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Pittsburgh; Pennsylvania; USA |
Polycystic kidney disease, Autosomal dominant polycystic kidney disease | NIDDK 5U01DK056961 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_152795 | SCR_000690 | SciCrunch Registry | Consortium of Radiologic Imaging Study of PKD | 2026-10-10 12:45:24 | 3 | |||||
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Duke O'Brien Center for Kidney Research Renal Genomics Core Resource Report Resource Website |
Duke O'Brien Center for Kidney Research Renal Genomics Core (RRID:SCR_015269) | access service resource, core facility, resource, service resource | Core facility that provides resources for investigators researching the genetic mechanisms of chronic kidney disease, cardiovascular disease, and hypertension. Its services include pre-study consultation, standardized services for DNA isolation and storage, and assisstance in carrying out molecular genetic studies. | chronic kidney disease research service, cardiovascular disease research service, hypertensions research service, experimental consultation |
is listed by: NIDDK Information Network (dkNET) has parent organization: Duke O'Brien Center for Kidney Research has parent organization: Duke University School of Medicine; North Carolina; USA has parent organization: Duke University; North Carolina; USA is organization facet of: Duke O'Brien Center for Kidney Research |
kidney disease, heart disease, hypertension, muscle disease | NIDDK P30DK096493 | Available to the research community | SCR_015269 | SciCrunch Registry | 2026-10-10 12:46:09 | 0 | ||||||||
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Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Resource Report Resource Website |
Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester (RRID:SCR_015313) | access service resource, data or information resource, disease-related portal, portal, resource, service resource, topical portal | Center that concentrates on the common, adult form of the disease, autosomal dominant PKD (ADPKD). The services provided focus on understanding the genetic basis of disease, more accurately monitoring disease progression and improving prognostics, and employing model systems to explore pathogenesis and conduct preclinical testing. | polycystic kidney disease, pathogenesis, preclinical testing |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic Minnesota; Minnesota; USA is parent organization of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core is parent organization of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core is parent organization of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core has organization facet: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core has organization facet: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core has organization facet: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core |
Polycystic Kidney Disease | NIDDK P30DK090728 | Available to the research community | SCR_015313 | SciCrunch Registry | 2026-10-10 12:39:31 | 0 | ||||||||
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George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Physiology Core Resource Report Resource Website |
George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Physiology Core (RRID:SCR_015266) | access service resource, core facility, resource, service resource | Core that provides measurement of serum and or urine Creatinine by Capillary Electrophoresis, measurement of serum and urine citrate by capillary electrophoresis, Microanalysis of serum and urine electrolytes by: Flame photometry, Atomic absorption or Ion-Selective Electrode, and Klotho IP-IB Assay. | physiology, kidney physiology, klotho assays |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Texas Southwestern Medical Center; Texas; USA has parent organization: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center is organization facet of: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center |
NIDDK P30DK079328 | Available to the research community, Fee for service | SCR_015266 | SciCrunch Registry | 2026-10-10 12:46:59 | 0 | |||||||||
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George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Cell Biology and Imaging Core Resource Report Resource Website |
George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Cell Biology and Imaging Core (RRID:SCR_015297) | access service resource, core facility, resource, service resource | Core that provides services such as imaging of rodent kidney and heart including functional MRI, processing of tissues for routine paraffin embedding, and single tubule isolation and immunocytochemistry. | cell imaging, cell biology, kidney function, pathology |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Texas Southwestern Medical Center; Texas; USA has parent organization: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center is organization facet of: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center |
NIDDK P30DK079328 | Available to the research community, Fee for service | SCR_015297 | SciCrunch Registry | 2026-10-10 12:46:59 | 0 | |||||||||
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University of Alabama at Birmingham-University of California San Diego O'Brien Center for Acute Kidney Injury Research Biostatistical Core Resource Report Resource Website |
University of Alabama at Birmingham-University of California San Diego O'Brien Center for Acute Kidney Injury Research Biostatistical Core (RRID:SCR_015283) | UAB-UCSD O'Brien Center, Biostatistics resource | access service resource, core facility, resource, service resource | Core provides statistical expertise in the conceptualization and design of projects, expertise in data management for the resulting clinical and bioinformatics data, and assistance with the preparation of project reports, presentations and manuscripts. | biostatistics, research project data, biostatistical |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Alabama at Birmingham School of Medicine; Alabama; USA has parent organization: University of California San Diego School of Medicine; California; USA has parent organization: UAB-UCSD Core Center for Acute Kidney Injury Research is organization facet of: UAB-UCSD Core Center for Acute Kidney Injury Research |
NIDDK P30 DK079337 | Available to the research community | SCR_015283 | SciCrunch Registry | O'Brien Center, Biostatistics resource, Core Center for Acute Kidney Injury Research, UAB-UCSD, Biostatistical Core | 2026-10-10 12:46:09 | 0 | |||||||
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George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Animal Models Core Resource Report Resource Website |
George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Animal Models Core (RRID:SCR_015292) | access service resource, core facility, resource, service resource | Core that generates and distributes several kidney-specific Cre recombinase and tetracycline-inducible activator and repressor lines to be crossed to floxed or tet responder lines provided by co-investigators. | animal models, pathophysiology, mice analysis |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Texas Southwestern Medical Center; Texas; USA has parent organization: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center is organization facet of: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center |
NIDDK P30DK079328 | Available to the research community, Fee for service | SCR_015292 | SciCrunch Registry | 2026-10-10 12:46:10 | 0 | |||||||||
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George M. O'Brien Kidney Center at Yale Human Genetics and Clinical Research Core Resource Report Resource Website |
George M. O'Brien Kidney Center at Yale Human Genetics and Clinical Research Core (RRID:SCR_015298) | access service resource, core facility, resource, service resource | Core that provides infrastructure support for several key steps in translational research, including development of HIC protocols, patient recruitment, patient DNA extraction and archiving, tools for high throughput SNP genotyping and DNA sequencing, and analysis of genetic linkage and linkage disequilibrium. | human genetics, kidney clinical research, translational research |
is listed by: NIDDK Information Network (dkNET) has parent organization: Yale School of Medicine; Connecticut; USA has parent organization: George M. O'Brien Kidney Center at Yale is organization facet of: George M. O'Brien Kidney Center at Yale |
NIDDK P30DK079310 | Available to the research community | SCR_015298 | SciCrunch Registry | 2026-10-10 12:46:10 | 0 | |||||||||
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George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Clinical and Translational Core Resource Report Resource Website |
George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Clinical and Translational Core (RRID:SCR_015295) | access service resource, core facility, resource, service resource | Core whose aim is to translate basic science research into effective diagnostic and therapeutic strategies that will improve the lives of patients by interrupting the pathogenesis of chronic kidney disease and its attendant high risk of cardiovascular disability and death. It combines comprehensive human genetics with phenotyping of subjects. | clinical, translational research, kidney disease, cardiovascular disease |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Texas Southwestern Medical Center; Texas; USA has parent organization: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center is organization facet of: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center |
kidney disease | NIDDK P30DK079328 | Available to the research community, Fee for service | SCR_015295 | SciCrunch Registry | 2026-10-10 12:46:09 | 0 | ||||||||
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NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources Resource Report Resource Website |
NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources (RRID:SCR_003074) | data or information resource, portal, resource, topical portal | THIS RESOURCE IS NO LONGER IN SERVICE, documented May 23, 2017. This website contains resources for obesity researchers including: Obesity Databases, Registries and Information; Obesity Multicenter Clinical Research; Obesity Basic Research Networks; Obesity Reagents; Obesity Services; Obesity Standardization Programs; Obesity Tissues, Cells, Animals; Obesity Useful Tools. | diabetes, type 1 diabetes, digestive disease, genetic metabolic disease, gene therapy, hematologic disease, hiv/aids research, immunological disease, kidney disease, liver disease, obesity, pancreas, urological disease, biotechnology, endocrinology, epidemiology, genetics, genomics, molecular hematology, molecular therapy, cystic fibrosis, polycystic kidney disease |
is related to: Rodent Operant Bucket project has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is parent organization of: CKD Biomarkers Consortium |
Type 1 diabetes, Type 2 diabetes, Diabetes | NIDDK | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-00551 | SCR_003074 | SciCrunch Registry | NIDDKObesity Resources | 2026-10-10 12:36:46 | 0 | ||||||
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Duke O'Brien Center for Kidney Research Clinical and Translational Core Resource Report Resource Website |
Duke O'Brien Center for Kidney Research Clinical and Translational Core (RRID:SCR_015272) | access service resource, core facility, resource, service resource | Core facility which investigates the connections between chronic kidney disease, cardiovascular disease, and hypertension. It focuses specifically on investigating the pathophysiology, epidemiology, and therapeutic response in on-going studies or existing datasets of one of the three diseases with the aim of relating data from individual diseases to each other. | translational kidney research, translational cardiovascular research, translational hypertension research |
is listed by: NIDDK Information Network (dkNET) has parent organization: Duke O'Brien Center for Kidney Research has parent organization: Duke University School of Medicine; North Carolina; USA has parent organization: Duke University; North Carolina; USA is organization facet of: Duke O'Brien Center for Kidney Research |
kidney disease, heart disease, hypertension, muscle disease | NIDDK P30DK096493 | Available to the research community | SCR_015272 | SciCrunch Registry | 2026-10-10 12:46:12 | 0 | ||||||||
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Pittsburgh Center for Kidney Research Cellular Physiology Resource Report Resource Website |
Pittsburgh Center for Kidney Research Cellular Physiology (RRID:SCR_015284) | access service resource, core facility, resource, service resource | Core that provides investigators with in vitro systems for the study of transport processes at the molecular, cell, and epithelial levels. | cellular physiology, membranes, cell function and structure, cell biology |
is listed by: NIDDK Information Network (dkNET) has parent organization: Pittsburgh Center for Kidney Research is organization facet of: Pittsburgh Center for Kidney Research |
NIDDK P30DK079307; University of Pittsburgh School of Medicine; Pennsylvania; USA ; Icahn School of Medicine at Mount Sinai; New York; USA |
Available to the research community | SCR_015284 | SciCrunch Registry | 2026-10-10 12:46:09 | 0 | |||||||||
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Pittsburgh Center for Kidney Research Single Nephron and Metabolomics Resource Report Resource Website |
Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285) | access service resource, core facility, resource, service resource | Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest. | single nephron, metabolomics, renal cells, cell analysis and function |
is listed by: NIDDK Information Network (dkNET) has parent organization: Pittsburgh Center for Kidney Research is organization facet of: Pittsburgh Center for Kidney Research |
NIDDK P30DK079307; University of Pittsburgh School of Medicine; Pennsylvania; USA ; Icahn School of Medicine at Mount Sinai; New York; USA |
Available to the research community | SCR_015285 | SciCrunch Registry | 2026-10-10 12:46:12 | 0 | |||||||||
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George M. O'Brien Kidney Center at Yale Renal Physiology Core Resource Report Resource Website |
George M. O'Brien Kidney Center at Yale Renal Physiology Core (RRID:SCR_015296) | access service resource, core facility, resource, service resource | Core provides specialized services and training for assessing renal function in small animals at the level of single tubules in vitro and in vivo (e.g. micropuncture, microperfusion, and tubule-specific microdissection), the whole kidney (e.g. clearance studies in anesthetized animals, perfusion fixation for histology studies), and the intact organism (e.g. balance studies in metabolic cages, acute and chronic BP measurements). | phenotyping assays, renal physiology, microperfusion |
is listed by: NIDDK Information Network (dkNET) has parent organization: George M. O'Brien Kidney Center at Yale has parent organization: Yale School of Medicine; Connecticut; USA is organization facet of: George M. O'Brien Kidney Center at Yale |
NIDDK P30DK079310 | Available to the research community | SCR_015296 | SciCrunch Registry | 2026-10-10 12:46:12 | 0 | |||||||||
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Assessment Serial Evaluation and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) Resource Report Resource Website |
Assessment Serial Evaluation and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) (RRID:SCR_014386) | ASSESS-AKI | data or information resource, data set, resource | A study which recruits patients with and without an episode of acute kidney injury during a hospitalization, and follows them longitudinally for major cardiac, renal and mortality events. An important aspect of the study is the prospective evaluation of potential biomarkers for renal and cardiac outcomes. | study, acute kidney injury, longitudinal, major cardiac event, major renal event, major mortality event, biomarker |
is listed by: NIDDK Research Resources is listed by: NIDDK Information Network (dkNET) |
NIDDK | Account required | http://www.niddk.nih.gov/research-funding/research-resources/Pages/default.aspx | SCR_014386 | SciCrunch Registry | Assessment Serial Evaluation and Subsequent Sequelae in Acute Kidney Injury | 2026-10-10 12:43:39 | 0 | ||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank (RRID:SCR_015319) | access service resource, core facility, resource, service resource | Core facility which provides mouse models and a biobank of tissues and other materials for research. | pkd, polycystic kidney disease, biobank, mouse model |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015319 | SciCrunch Registry | 2026-10-10 12:46:12 | 0 | ||||||||
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Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core Resource Report Resource Website |
Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core (RRID:SCR_015308) | access service resource, core facility, resource, service resource | Core services include mutation screening of cell lines derived from ADPKD patients, mutation screening of large, typical ADPKD populations, genetic screening of atypical PKD families, cystic Kidney and Liver Disease Biobank (CKLBB) from ADPKD patients, and urine collection and fractionation. | molecular genetics, biomarker, mutation screening, PKD |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic Minnesota; Minnesota; USA has parent organization: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester is organization facet of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester |
Polycystic Kidney Disease | NIDDK P30DK090728 | Available to the research community | SCR_015308 | SciCrunch Registry | 2026-10-10 12:46:12 | 0 | ||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering (RRID:SCR_015323) | access service resource, core facility, resource, service resource | Core faiclity that provides researchers with cell culturing and engineering services. | pkd, polycystic kidney disease, cell culture, cell engineering |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015323 | SciCrunch Registry | 2026-10-10 12:46:10 | 0 |
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