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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://matsen.fhcrc.org/pplacer/
Software that places query sequences on a fixed reference phylogenetic tree to maximize phylogenetic likelihood or posterior probability according to a reference alignment. Pplacer is designed to be fast, to give useful information about uncertainty, and to offer advanced visualization and downstream analysis.
Proper citation: Pplacer (RRID:SCR_004737) Copy
Standalone software programs that can be used to calculate how well tetranucleotide usage patterns in DNA sequences correlate. Such correlations can provide valuable hints on the relatedness of DNA sequences.
Proper citation: TETRA (RRID:SCR_004573) Copy
A web-based browser for Gene Ontology terms and annotations, which is provided by the UniProtKB-GOA group at the EBI. It is able to offer a range of facilities including bulk downloads of GO annotation data which can be extensively filtered by a range of different parameters and GO slim set generation. The software for QuickGO is freely available under the Apache 2 license. QuickGO can supply GO term information and GO annotation data via REST web services.
Proper citation: QuickGO (RRID:SCR_004608) Copy
https://sites.google.com/a/lbl.gov/biopig/
Software providing a framework for genomic data analysis using Apache Pig and Hadoop.
Proper citation: BioPig (RRID:SCR_004636) Copy
https://github.com/lmrodriguezr/nonpareil
Estimate average coverage and create Nonpareil curves for metagenomic datasets.
Proper citation: Nonpareil (RRID:SCR_004629) Copy
https://code.google.com/p/destruct/
A software tool for identifying structural variation in tumour genomes from whole genome illumina sequencing.
Proper citation: deStruct (RRID:SCR_004747) Copy
http://omics.informatics.indiana.edu/AbundanceBin/
An abundance-based software tool for binning metagenomic sequences, such that the reads classified in a bin belong to species of identical or very similar abundances. AbundanceBin also gives estimations of species abundances and their genome sizes -two important characteristic parameters for a microbial community.
Proper citation: AbundanceBin (RRID:SCR_004648) Copy
http://compbio.cs.sfu.ca/software-variation-hunter
A software tool for discovery of structural variation in one or more individuals simultaneously using high throughput technologies.
Proper citation: VariationHunter (RRID:SCR_004865) Copy
http://www.ncbi.nlm.nih.gov/pubmed/
Public bibliographic database that provides access to citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. PubMed citations and abstracts include fields of biomedicine and health, covering portions of life sciences, behavioral sciences, chemical sciences, and bioengineering. Provides access to additional relevant web sites and links to other NCBI molecular biology resources. Publishers of journals can submit their citations to NCBI and then provide access to full-text of articles at journal web sites using LinkOut.
Proper citation: PubMed (RRID:SCR_004846) Copy
http://www.cbcb.umd.edu/software/phymm/
Software for Phylogenetic Classification of Metagenomic Data with Interpolated Markov Models to taxonomically classify DNA sequences and accurately classify reads as short as 100 bp. PhymmBL, the hybrid classifier included in this distribution which combines analysis from both Phymm and BLAST, produces even higher accuracy.
Proper citation: Phymm and PhymmBL (RRID:SCR_004751) Copy
Wiki forum providing an extensive catalogue of manually categorized analysis tools, technologies and information about service providers, maintained by the members of the SEQanswers community. * Minimum Information about a high-throughput Sequencing Experiment * Software Hub: The place to add to, edit or browse the software database on SEQwiki. * Service Providers: Browse or edit the list of NGS service facilities. * How-to Hub: Mini reviews for the most used tools broken down by common tasks. * Developers Hub: The place to discuss the development of the SEQwiki site and its associated data. See also publishing SEQ*. * Publications: Publication about SEQwiki and selected citations.
Proper citation: SEQanswers Wiki (RRID:SCR_004810) Copy
http://www.ncbi.nlm.nih.gov/sra
Repository of raw sequencing data from next generation of sequencing platforms including including Roche 454 GS System, Illumina Genome Analyzer, Applied Biosystems SOLiD System, Helicos Heliscope, Complete Genomics, and Pacific Biosciences SMRT. In addition to raw sequence data, SRA now stores alignment information in form of read placements on reference sequence. Data submissions are welcome. Archive of high throughput sequencing data,part of international partnership of archives (INSDC) at NCBI, European Bioinformatics Institute and DNA Database of Japan. Data submitted to any of this three organizations are shared among them.
Proper citation: NCBI Sequence Read Archive (SRA) (RRID:SCR_004891) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2nd, 2023. Sequence composition based classifier for metagenomic sequences. It works by capturing signatures of each sequence based on the sequence composition. Each sequence is modeled as a walk in a de Bruijn graph with underlying Markov chain properties. ClaMS captures stationary parameters of the underlying Markov chain as well as structural parameters of the underlying de Bruijn graph to form this signature. In practice, for each sequence to binned, such a signature is computed and matched to similar signatures computed for the training sets. The best match that also qualifies the normalized distance cut-off wins. In the case that the best match does not qualify this cut-off, the sequence remains un-binned.
Proper citation: Classifier for Metagenomic Sequences (RRID:SCR_004929) Copy
http://www.moleculardevices.com/Products/Software/GenePix-Pro.html
Industry standard microarray image analysis software because of its unique combination of imaging and analysis tools, visualizations, automation capabilities, performance and intuitive workflows.
Proper citation: GenePix Pro (RRID:SCR_010969) Copy
http://berry.engin.umich.edu/oligoarray2_1/
A free software that computes gene specific oligonucleotides for genome-scale oligonucleotide microarray construction.
Proper citation: OligoArray (RRID:SCR_010961) Copy
http://www.complex.iastate.edu/download/Picky/
A software tool for selecting optimal oligonucleotides (oligos) that allows the rapid and efficient determination of gene-specific oligos based on given gene sets, and can be used for large, complex genomes such as human, mouse, or maize.
Proper citation: Picky (RRID:SCR_010963) Copy
http://pbil.univ-lyon1.fr/roso/help.php
A software to design optimized oligonucleotide probes (size over 25 nucleotides) for microarrays.
Proper citation: ROSO (RRID:SCR_010967) Copy
Database for microarray data storage, retrieval, analysis, and visualization.
Proper citation: UNC Microarray Database (RRID:SCR_010979) Copy
http://www.illumina.com/software/genomestudio_software.ilmn
Visualize and analyze data generated by all of Illumina''s platforms.
Proper citation: GenomeStudio (RRID:SCR_010973) Copy
http://www.bu.edu/jlab/wp-assets/ComBat/Abstract.html
Adjusting batch effects in microarray expression data using Empirical Bayes methods.
Proper citation: ComBat (RRID:SCR_010974) Copy
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