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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.demogr.mpg.de/databases/ktdb/
A database that includes data on death counts and population counts classified by sex, age, year of birth, and calendar year for more than 30 countries. This database was established for estimating the death rates at the highest ages (above age 80). The core set of data in the database was assembled, tested for quality, and converted into cohort mortality histories by V��in�� Kannisto, the former United Nations advisor on demographic and social statistics. Comparable materials on England and Wales, was made available by A. Roger Thatcher, the former Director of the Office of Population Censuses and Surveys and Registrar-General of England and Wales (Kannisto, 1994). The Kannisto-Thatcher database was computerized under the supervision of James W. Vaupel at the Aging Research Unit of the Centre for Health and Social Policy at Odense University Medical School in 1993. Currently, the database is maintained by the Max Planck Institute for Demographic Research, Germany.
Proper citation: Kannisto-Thatcher Database on Old Age Mortality (RRID:SCR_008936) Copy
A biological database and software tool catalog based on text mined and human annotated url mentions in PubMed abstracts. Data are annotated as to the author''''s country of origin and url status is checked.
Proper citation: DaTo (RRID:SCR_010280) Copy
Citation-ranked antibody search engine that provides a simple way to find antibodies that work. They use the number of citations as a transparent method to rank antibodies. Nobody can pay to be ranked higher. They are always looking for more commercial and academic antibodies to make CiteAb better. There is no charge to list.
Proper citation: CiteAb (RRID:SCR_009653) Copy
Database to advance the availability and use of public health data for science and policy making that includes data from all weekly notifiable disease reports for the United States dating back to 1888. Additional U.S. and international data will be released twice yearly.
Proper citation: Project Tycho (RRID:SCR_010489) Copy
A large multi-site pediatric MRI and genetics data resource to facilitate studies of the genomic landscape of the developing human brain. It includes information about the developing mental and emotional functions of the children to understand the genetic basis of individual differences in brain structure and connectivity, cognition, and personality. Investigators on the project are studying 1400 children between the ages of 3 and 20 years so that links between genetic variation and developing patterns of brain connectivity can be examined. Investigators interested in the effects of a particular gene will be able to search the database for any brain areas or connections between areas that differ as a function of variation in a particular gene, and also to determine if the genes appear to affect the course of brain development at some point during childhood. A data exploration tool has been created for mapping and analyzing MRI data sets collected for PING and related developmental studies. Approved investigators will be able to view raw image sets and derived 3D brain maps of MRI and DTI data, conduct hypothesis testing, and graph brain area measures as they change across the time course of development. PING Cores * Coordinating Core: Functions include project management, screening of participants and maintaining the database * Neuroimaging Core: applying a standardized high-resolution structural MRI protocol involving 3-D T1-weighted scans, a T2-weighted volume, and a set of diffusion-weighted scans with multiple b values and diffusion directions, scans to estimate MRI relaxation rates, and gradient echo EPI scans for resting state fMRI. Importantly, adaptive motion compensation, using ����??PROMO����??, a novel real-time motion correction algorithm will be used. Specific PING protocols for each scanner manufacturer: ** PING MRI Protocol - GE ** PING MRI Protocol - Philips ** PING MRI Protocol - Siemens * Assessment Core: Cognitive assessments for the PING project are conducted using the NIH Toolbox for Cognition. * Genomics Core: functions as a central repository for receipt of saliva samples collected for each study participant. Once received, samples are catalogued, maintained, and DNA is extracted using state-of-the-field laboratory techniques. Ultimately, genome-wide genotyping is performed on the extracted DNA using the Illumina Human660W-Quad BeadChip. PING involves 10 sites throughout the country including UCSD, University of Hawaii, Scripps Genomics, UCLA, UC Davis, Kennedy Krieger Institute/Johns Hopkins, Sacker Institute/Cornell University, University of Massachusetts, Massachusetts General Hospital/Harvard, and Yale. Families who may want to participate in the study, or others who want to know more about it, may email questions to ping (at) ucsd.edu.
Proper citation: Pediatric Imaging Neurocognition and Genetics (RRID:SCR_008953) Copy
http://www.accessdata.fda.gov/scripts/opdlisting/oopd/index.cfm
Database of Orphan Drug Product designations. Searches may be run by entering the product name, orphan designation, and dates. Results can be displayed as a condensed list, detailed list, or an Excel spreadsheet.
Proper citation: Search Orphan Drug Designations and Approvals (RRID:SCR_010256) Copy
http://wiki.wholebraincatalog.org/wiki/Dangerous_Ideas
THIS RESOURCE IS NO LONGER IN SERVICE This is the website for a weekly social event called Dangerous Ideas, to promote more cross talk and cross pollination of ideas. There is a list of links to interesting new tools and technologies in the realm of computation and science. We'll be experimenting with webcasting this so others who can't physically join us can share in seeing what we think is cool. Its a completely open event-- anyone is welcome to join in, but should be prepared to present!
Proper citation: Dangerous Ideas (RRID:SCR_010531) Copy
http://www.accessdata.fda.gov/scripts/animaldrugsatfda/index.cfm?gb=1
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Database of approved veterinary drugs run by the FDA.
Proper citation: AnimalDrugsatFDA (RRID:SCR_010257) Copy
http://www.niehs.nih.gov/news/newsletter/2006/march/science-genetic.cfm
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. The NIEHS Genetic Alterations in Cancer (GAC) knowledgebase is a comprehensive collection of data compiled from studies reported in the published literature on genetic alterations in tumors associated with exposure to specific chemical, physical, or biological agents that can be linked to genes implicated in the development of cancers. GAC provides access to data from peer reviewed journals for hundreds of studies of gene mutations, loss of heterozygosity, and/or chromosome changes in tumors from humans, mice, or rats. Results are summarized in tables and graphic profiles that show the incidence (percent) of tumors with alterations in each gene that has been studied. Detailed data tables display results for each subject studied in the cited reference and the reference ID is hyperlinked to its PubMed abstract for more information. A mutation spectrum for individual genes and links to gene information from The Cancer Genome Anatomy Project and the Rat Genome Database are also provided.
Proper citation: Genetic Alterations in Cancer (RRID:SCR_010533) Copy
http://www.premierbiosoft.com/dnamicroarray/index.html
Oligo and cDNA Microarray Design Software that designs thousands of primers and probes for oligo and cDNA microarrays in seconds.
Proper citation: Array Designer (RRID:SCR_010960) Copy
A commercial software tool for statistical analysis.
Proper citation: SyStat (RRID:SCR_010455) Copy
Powerful, accessible statistical tools for fast visualization and analysis of microarrays - expression arrays, miRNA, exon arrays and genomics copy number data.
Proper citation: GeneSpring GX (RRID:SCR_010972) Copy
http://fcon_1000.projects.nitrc.org/indi/pro/nyu.html
Datasets including a collection of scans from 49 psychiatrically evaluated neurotypical adults, ranging in age from 6 to 55 years old, with age, gender and intelligence quotient (IQ) information provided. Future releases will include more comprehensive phenotypic information, and child and adolescent datasets, as well as individuals from clinical populations. The following data are released for every participant: * At least one 6-minute resting state fMRI scan (R-fMRI) * * One high-resolution T1-weighted mprage, defaced to protect patient confidentiality * Two 64-direction diffusion tensor imaging scans * Demographic information (age, gender) and IQ-measures (Verbal, Performance, and Composite; Weschler Abbreviated Scale of Intelligence - WASI) * Most participants have 2 R-fMRI scans, collected less than 1 hour apart in the same scanning session. Rest_1 is always collected first.
Proper citation: NYU Institute for Pediatric Neuroscience Sample (RRID:SCR_010458) Copy
http://fcon_1000.projects.nitrc.org/indi/pro/VirginiaTech.html
Dataset including a T1 weighted anatomical image as well as two 10-minute resting state scans acquired during the same session from 25 psychiatrically screened healthy adults (community sample) ranging in age from 18 to 65 years old, with age, sex, education level, and ethnicity provided. Some subjects also returned several weeks after the first scan for a second scanning session. The number of days between scan sessions, for subjects that had two sessions, is indicated in the demographics spreadsheet. The study scanning protocol included: # 13 sec localizer # 4 minute 38 second T1 weighted anatomical # Subject given instructions for resting state scan #1 # 10 minute 4 second resting state scan #1 # Subject given instructions for resting state scan #2 # 10 minute 4 second resting state scan #2 Scanning was performed on one of three different 3T Siemens TIM TRIOs at the Human Neuroimaging Lab at Baylor College of Medicine in Houston, Texas. All scans were acquired using the standard Siemen''s TIM 12-channel head matrix. The resting state scans were acquired with a custom sequence that is a slight modification to the standard Siemen''s EPI sequence that supports real-time fMRI. Images were acquired slightly oblique to minimize dephasing in the orbito-frontal cortex. Detailed scanning parameters are included in separate .pdf files.
Proper citation: Virginia Tech Carilion Research Institute Sample (RRID:SCR_010459) Copy
A portal that allows users to track specific words, phrases or nearby relationships from social media sources including Twitter, Digg and others. Datasift aggregates, filters, records, and analyzes real-time data from a variety of social sources using our Curation Stream Definition Language (CSDL) allowing customers to curate their own news.
Proper citation: DataSift (RRID:SCR_010708) Copy
http://www.immunospot.com/index.php?id=77
ELISpot analyzing software
Proper citation: ImmunoSpot Software for Analyzing ELISPOT Assays (RRID:SCR_011082) Copy
http://www.exiqon.com/mirna-array-software
Software for fast and accurate analysis of miRCURY LNA microRNA Array data.
Proper citation: miRCURY LNA microRNA Array Analysis Software (RRID:SCR_010952) Copy
http://carta.anthropogeny.org/libraries
CARTA is developing two virtual libraries of books relevant to Anthropogeny * Library of Anthropogeny: A collection of book titles on human origins and human evolution, arranged chronologically. * Library of Primatology: A collection of book titles on non-human primate evolution, including basic biology, ecology and behavior. A listing of the book titles are made available for public interest.
Proper citation: CARTA Libraries (RRID:SCR_010712) Copy
http://realtimegenomics.com/products/variant-1.0
The product line encompasses distinct products for the specific needs of clinical research, saving time and money while allowing customers to focus on the answers they need most.
Proper citation: RTG Variant (RRID:SCR_010805) Copy
http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/6219
A public-use microdata sample focusing on the older population created from the 1990 census. This sample consists of 3 percent of households with at least one member aged 60 or older. Although, the highest age presented is age 90, this allows analysis of data on the very old for most states with a reasonable degree of reliability. Since data for all members in households containing a person 60 years and over will be on the file, users will be able to analyze patterns such as living arrangements and sources of household income from which older members may benefit. Additionally, users will be able to augment the PUMS-O sample with a PUMS file. The Census Bureau has issued two regular PUMS files for the entire population. One PUMS file will contain 1 percent of all households; the other PUMS file will contain 5 percent of all households. Both files have most sample data items, and differ only in geographical composition. The 1-percent file contains geographic areas that reflect metropolitan vs. non-metropolitan areas. The 5-percent file shows counties or groups of counties as well as large sub-county areas such as places of 100,000 or more. The geography on the 5-percent PUMS file matches that of the PUMS-O file. Since data for different households are present on the two files, users can merge the PUMS-O file with the 5-percent PUMS to construct an 8-percent sample. However, weighted averages must be constructed for any estimates created because each sample yields state-level estimates. Thus, it is possible to analyze substate areas even for the very old. In states where the geographic areas identified on the PUMS-O and the 5-percent PUMS are coterminous with State Planning and Service Areas (used by service providers in relation to the Older Americans Act), the Planning and Service Areas are identified. * Dates of Study: 1990-2000 Links: 1980: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/08101 2000: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/04204
Proper citation: Public Use Microdata Sample for the Older Population (RRID:SCR_010487) Copy
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