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http://harvard.eagle-i.net/i/0000012e-590e-5fe8-55da-381e80000000

Core facility that provides the following services: Data management service, SNP genotyping service. The Genetics Core was established in 1991 with the aim of promoting and facilitating genetic studies of diabetes and its complications in humans at the Joslin Diabetes Center and collaborating institutions. More than 1,000 DNA samples from human subjects have been collected in these years and are available to researchers. The Genetics Core also provides services assisting investigators in the use of these samples. Investigators wishing to use the Core resources should contact Dr. Alessandro Doria by phone at x4340 or (617) 732-2406, or by e-mail. A detailed project description is required for the use of DNA samples. There is no restriction on the Core access.

Proper citation: JDC Genetics Core (RRID:SCR_009879) Copy   

•   Source: SciCrunch Registry
  

https://joslinresearch.org/drc-cores/Animal-Physiology-Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides technically advanced physiological evaluation of metabolism in diabetes, obesity, and their associated complications in rodents for DRC investigators and outside users. It also provides training of investigators and trainees in several physiological procedures.

Proper citation: Joslin Diabetes Center Animal Physiology Core Facility (RRID:SCR_009876) Copy   

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http://ohsu.eagle-i.net/i/0000012b-3afd-4e95-62b8-f47280000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Monoclonal antibody development. The Oregon Stem Cell Center Monoclonal Antibody Core is focused on developing monoclonal antibodies that aid investigators in the identification and isolation of novel stem and progenitor cell populations. To enable isolation of live stem cells, personnel within the Monoclonal Antibody Core develop monoclonal antibodies directed against cell surface antigens. Personnel within the laboratory are highly skilled in all aspects of monoclonal antibody generation and characterization, and work closely with investigators throughout the entire immunization, fusion, and screening process. The monoclonal antibody core offers a full complement of services related to the development of monoclonal antibodies.

Proper citation: Oregon Stem Cell Center Monoclonal Antibody Core (RRID:SCR_009997) Copy   

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http://eagle-i.itmat.upenn.edu/i/00000141-9868-14b8-91c7-0c6080000000

Core facility that provides the following services: Hydrogel consultation service, ECM-coated acrylamide hydrogels, Hands-on guidance for cell lysis and molecular/cellular analysis, Preparation of acrylamide-based hydrogel training, Second harmonic generation microscopy, Atomic force microscopy. The Biomechanics Core works with ITMAT faculty from Penn, ITMAT partner institutions, and members of the ITMAT Program in Translational Biomechanics. Consultation and initial pilot experiments performed with the Biomechanics Core are free-of-charge to ITMAT faculty from Penn, ITMAT partner institutions, and members of the ITMAT Program in Translational Biomechanics.

Proper citation: Penn BioMechanics Core Facility (RRID:SCR_009998) Copy   

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http://ohsu.eagle-i.net/i/0000012a-865d-c25e-048a-d9aa80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6, 2022. Core facility that provides the following services: Consultation on protocol development and design process, Exercise testing service, Dual energy x-ray absorptiometry service. The Bionutrition Unit provides nutrition, body composition, and energy expenditure services. Bionutritionist and research kitchen staff are highly experienced and trained to assist investigators with the design and implementation of research meals, feeding studies, and related research. The Bionutrition Unit also provides a variety of energy expenditure and body composition measurement services using a range of equipment.

Proper citation: Oregon Clinical and Translational Research Institute Bionutrition Unit (RRID:SCR_009995) Copy   

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https://joslinresearch.org/drc-cores/Advanced-Microscopy-Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for performing specific morphological procedures, providing training and access to equipment, maintaining the specialized microscopes, and giving advice and interpretation.

Proper citation: Joslin Diabetes Center Advanced Microscopy Core Facility (RRID:SCR_009875) Copy   

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https://www.ohsu.edu/octri/clinical-and-translational-research-center

Provides nursing, bionutrition, study coordination, and laboratory services and support. Laboratory is designed and equipped to perform both basic and specialized research assays and sample processing in support of translational research studies and trials. Laboratory staff have extensive experience in performance of wide variety of analytical and genetic based assays and procedures.

Proper citation: OHSU Oregon Clinical and Translational Research Center Core Facility (RRID:SCR_009996) Copy   

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http://hunter-cuny.eagle-i.net/i/00000136-a791-3ad9-949b-425080000000

Core facility that provides the following services: Single-crystal X-ray analysis. The mission of the CUNY X-ray Diffraction (X-ray) Facility is to perform single-crystal analyses for the structure determination of molecules, which make up a crystal. This technique is called single-crystal X-ray crystallography. It is the ultimate method for definitive determination of molecular structures at the atomic level for both organic and inorganic compounds. Its uses range from simple identification of compounds to various exotic configuration and conformational studies.

Proper citation: Hunter X-ray Diffraction Facility (RRID:SCR_009872) Copy   

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https://joslinresearch.org/drc-cores/Advanced-Genomics-and-Genetics-Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for genetic and genomic analysis, including DNA extraction from blood, access to DNA collections from the Core?s repository, SNP genotyping, and support for gene expression studies based on both high-density oligonucleotide arrays and real-time quantitative PCR.

Proper citation: Joslin Diabetes Center Advanced Genomics and Genetics Core Facility (RRID:SCR_009873) Copy   

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https://www.ohsu.edu/proteomics-shared-resource

Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU.

Proper citation: OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) Copy   

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http://ohsu.eagle-i.net/i/0000012b-00c9-007b-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: G-banded karyotyping, Sister chromatid exchange service, Fluorescent in situ hybridization, Chromosome breakage and radial formation analysis, Ploidy/Aneuploidy Assessment, Mitotic index service. A fee-for-service cytogentics laboratory available to genetics researchers to assist in development and execution of cytogenetics experiments for research purposes. Through rigorous standardization of protocols and customized experiment development, the OHSU Research Cytogenetics Core Laboratory provides high quality metaphase and interphase cytogenetic data to the OHSU research community. Services are also available to non-profit and commercial investigators located in Oregon and elsewhere.

Proper citation: OHSU Research Cytogenetics Core Laboratory (RRID:SCR_009992) Copy   

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http://howard.eagle-i.net/i/00000135-5958-291c-bf4c-ca4080000000

Howard Nanoscale Science and Engineering Facility (HNF) occupies a specially renovated wing on the first floor of the Engineering Building.The five large laboratories cover ~6000 sq. ft. of space and the HNF has about 2000 sq ft of contiguous office space. The HNF is an established centralized user facility containing over $17M of micro- and nano fabrication and characterization equipment, accessible by external and internal academic, government and industrial users. Currently, HNF has integrated facilities in the following categories: Lithography Facilities Nanofabrication Facilities Plasma Etching / Deposition Facilities CVD Deposition Facilities (SiC,GaN) Nanomembrane Facilities Characterization Facilities Computer Facilities Societal and Ethical Issues

Proper citation: Howard Nanoscale Science and Engineering Facility (RRID:SCR_009867) Copy   

•   Source: SciCrunch Registry
  

http://ohsu.eagle-i.net/i/0000012b-00ce-7b4f-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. The Neuropathology Core of the Layton Center for Aging and Alzheimer?s Disease Center is dedicated to studying, through autopsy, the brains of individuals who have been followed longitudinally in the Oregon Alzheimer?s Disease Center Clinical Core. Requests for tissue from the Oregon Brain Bank should be directed to Dr. Randall Woltjer. Dr. Woltjer will be glad to communicate with investigators regarding their tissue needs and to assist them in identifying suitable materials for their studies. Material Transfer Agreements between the requesting and sending institutions are needed before shipment.

Proper citation: OHSU Neuropathology Core (RRID:SCR_009988) Copy   

•   Source: SciCrunch Registry
  

http://howard.eagle-i.net/i/00000135-589a-a87e-bf4c-ca4080000000

Core facility that provides the following services: Equipment access, Training on proteomics equipment. Mission: To use mass spectrometry for studies of infectious and chronic diseases and to promote and facilitate biomedical and translational research at Howard University Objectives: To provide modern analytical instrumentation, technical expertise and essential services for biomolecular analysis To provide a broader training experience for students and faculty in biomolecular analysis through methodology- centered seminars, workshops, mini-courses, and internships To foster new multidisciplinary research collaborations using modern Proteomics technology The RCMI Proteomics Core Facility runs several research projects and provides collaborative consolidation of instrumentation, technical expertise, and support personnel to enhance the impact and availability of Mass Spectrometry and other analytical techniques for biological and biomedical science community at Howard University

Proper citation: Howard RCMI Proteomics Facility (RRID:SCR_009868) Copy   

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https://www.ohsu.edu/medicinal-chemistry-core/nmr

Core facility that provides the following services: NMR instrument training. A facility that uses a state-of-the-art NMR spectrometer to verify or determine the structure of organic molecules. Housed in the Department of Physiology and Pharmacology, it is designed to exploit the power of designed small molecules as probes of protein and cellular function and to provide the foundation for the development of prototypic therapeutic agents.

Proper citation: OHSU Nuclear Magnetic Resonance Core Facility (RRID:SCR_009989) Copy   

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http://howard.eagle-i.net/i/00000134-aa20-c323-bf4c-ca4080000000

Core facility that provides the following services: SNP detection service, DNA sequencing service, EBV cell transformation service, DNA sequencer access. The molecular genetics research interests are in human population genetics, anthropological genetics, immunogenetics, and the genetics of complex diseases. Ultimate goals surround elucidating questions of human variation, the evolutionary history of genes within populations and how these gene histories are involved in the etiology of complex diseases. While the laboratory''s research goals have shared consequences for all humanity, specific interests focus on populations of African ancestry. Operational Objectives: 1. Develop a SNP database for mapping functional mutations linked to diseases common in African peoples. 2. Utilization of evolutionary history of candidate genes to identify polymorphisms that are associated with diseases. 3. Exploit the linkage disquilibrium generated by admixture in the African American population for gene mapping.

Proper citation: Howard Molecular Genetics Core (RRID:SCR_009865) Copy   

•   Source: SciCrunch Registry
  

http://ohsu.eagle-i.net/i/0000013b-95a6-bd56-c825-3bd680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Automated DNA sequencing, Realtime PCR analysis and SNP analysis, Automated DNA and RNA preps using robotics, Lentiviral vector preparation for cDNA and shRNA transduction and infection, Semi-automated large-scale genomic DNA preparations., Freezing, thawing, and amplification of cell lines, Preparation of both routine and exotic cell culture medium. The Molecular and Cellular Biology Core provides services, reagents and training for all aspects of molecular biology and cell culture. Services include DNA sequencing, real-time PCR, genotyping, robotic RNA and DNA purification, monkey-specific cDNAs, and customized media and buffers for cell culture. The core also produces lentiviral vectors for cDNA and shRNA delivery. Core personnel assist researchers in maintaining and storing cell lines. The core makes available state-of-the-art equipment, including a 969capillary DNA sequencer, realtime qRT-PCR platforms, and fluorometers for cell-based kinetic analyses..

Proper citation: OHSU Molecular and Cellular Biology Core Laboratory (RRID:SCR_009986) Copy   

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http://eagle-i.itmat.upenn.edu/i/00000139-496b-76ed-eb5b-b63c80000000

Core facility that provides the following services: Informatics consultative support. The staff of this core gives guidance and/or coordinates data management, capture and analysis on behalf of the investigator within the Institute and assists more broadly with computing issues related to the approved protocol. This core provides services to investigators for their Clinical and Translational Research Center (CTRC)-approved studies that are utilizing other CTRC core services.

Proper citation: Penn/CHOP CTRC Informatics Services Core (RRID:SCR_009866) Copy   

•   Source: SciCrunch Registry
  

http://ohsu.eagle-i.net/i/0000012a-24fd-6e5c-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Monoclonal antibody generation, Scaleup production and purification of antibody from existing cell lines. The VGTI Monoclonal Core offers two basic services: the generation of new monoclonal antibodies and the scaleup production and purification of antibody from existing cell lines (a stand -alone phase IV).

Proper citation: OHSU Monoclonal Antibody Core Laboratory (RRID:SCR_009987) Copy   

•   Source: SciCrunch Registry
  

http://howard.eagle-i.net/i/00000134-a996-f935-bf4c-ca4080000000

The Biostatistics Core is a resource for Howard University Cancer Center (HUCC) that provides statistical and computer/data management support services to affiliated members. Members of the Biostatistics Core provide advice in matters of design, randomization, power analysis, data processing, quality control, database development and management and statistical analysis in clinical and population based studies. The Biostatistics Core aims at excellence in biostatistical and methodological issues related to cancer studies and to advocate proper use of statistics, data monitoring and data analysis.

Proper citation: Howard Biostatistics Core (RRID:SCR_009863) Copy   

•   Source: SciCrunch Registry