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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.ibgm.med.uva.es/files/upload/manual/casyoperatormanual.pdf
Tool for the qualitative and quantitative assessment of cell cultures including standardized cell counting methods, viability checks, aggregation correction, volumetric measurement with high measuring range dynamics. It enables to create optimal settings for measuring certain cell population numbers (based on size and gating strategies).
Proper citation: CASY Cell Counter and Analyser System Model TT (RRID:SCR_002080) Copy
Commercial company that develops and sells flow cytometry assay development software and analytical cytology tools.
Proper citation: Soft Flow (RRID:SCR_002599) Copy
http://www.proteinbiotechnologies.com/
Protein Biotechnologies Inc., a San Diego, California based company, provides global pharmaceutical, biotechnology, government and academic institutions with human clinical specimen derivatives and high-throughput protein and tissue microarrays. With the largest collection of ready-to-use, clinically defined, pathology-validated human specimen derivatives on the market, Protein Biotechnologies facilitates biomedical research and drug discovery efforts for cancer, neurodegenerative diseases, cardiovascular diseases, diabetes / obesity and autoimmune disease research. To facilitate high-throughput screening of human clinical specimens, Protein Biotechnologies provides its tissue lysate library on ready-to-use protein microarrays. And, for protein localization, immunohistochemical and in-situ hybridization studies, Protein Biotechnologies'' tissue microarrays are an ideal method for studying multiple human cancer / normal tissues in a single assay. Key Products & Services: * Reverse Phase Protein Microarrays * Human Clinical Tissue Lysates * Tissue Microarrays * Primary & Secondary Antibodies * Supplemental Research Reagents * Protein, RNA and DNA Isolation and Purification * Peptide Synthesis * Custom Protein and Peptide Microarray Design and Manufacturing * Custom Antibody Production
Proper citation: Protein Biotechnologies (RRID:SCR_004893) Copy
http://www.t1diabetes.nih.gov/T1D-PTP/
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. Investigator access is provided to the established facilities and expertise needed to extend, enhance and validate preclinical studies of promising new therapeutics in cases where additional preclinical testing is needed to validate potential therapies under disease-specific conditions and in multiple animal models before therapeutics can enter the Type 1 Diabetes Rapid Access to Intervention Development (T1D-RAID) development pipeline. The T1D-RAID program provides resources for pre-clinical development of drugs, natural products, and biologics that will be tested as new therapeutics in type 1 diabetes clinical trials. The T1D-RAID program is not currently accepting applications. The T1D-PTP program currently supports two contracts, which are separate from each other and from the T1D-RAID NCI contract resources, to assist in preclinical development of therapeutics for T1D: * Agents to be tested for Preclinical Efficacy in Prevention or Reversal of Type 1 Diabetes in Rodent Models. Type 1 Diabetes Preclinical Testing Program (T1D-PTP) (NOT-DK-09-006) * Needs for Preclinical Efficacy Testing of Promising Agents to Prevent or Reverse Diabetic Complications (NOT-DK-09-009) The T1D-RAID and T1D-PTP are programs intended to remove the most common barriers to progress in identification and development of new therapies for Type 1 Diabetes. The common goal of these programs is to support and provide for the preclinical work necessary to obtain proof of principle establishing that a new molecule or novel approach will be a viable candidate for expanded clinical evaluation.
Proper citation: Type 1 Diabetes Preclinical Testing Program (RRID:SCR_006861) Copy
Provides equipment for TEER measurement, nitric oxide testing, and electro-physiology applications.
Proper citation: World Precision Instruments (RRID:SCR_008593) Copy
Commercial instrument supplier for human activity monitors. ActiGraph devices are used by researchers and clinicians in hundreds of universities and research organizations in more than 56 countries. ActiGraph activity monitors are the most validated and widely used devices of their kind. ActiGraph activity monitors use triaxial accelerometers and our validated proprietary filtering algorithms to accurately measure the amount and intensity of human activity. They are powered by rechargeable lithium ion batteries, and battery charging and communication are accomplished via a standard USB connection. All ActiGraph activity monitors can be worn at the waist or wrist and are suitable for subjects of all ages. ActiGraph devices have been used in hundreds of research studies in nearly 60 countries around the world since 1992. Leading research facilities including the U.S. National Institute of Health (NIH), the Institute of Child Health in the UK, and Karolinska Institutet in Sweden rely on our products to provide objective activity measurement in dozens of areas including obesity, diabetes, sleep, elderly behavior, and athletics. ActiGraph often works with scientific organizations to develop and implement software and hardware features that reflect the evolving needs of the research community. ActiGraph devices are well recognized as some of the most accurate activity measurement products on the market. Extensive research has confirmed our accuracy against the VO2 and doubly labeled water (DLW) methods of estimating energy expenditure. Keywords: Device, Researcher, Clinician, University, Research, Organization, Obesity, Diabetes, Sleep, Elderly, Behavior, Athletics, Scientific, Activity monitor, Physical, Measurement, Human, Activity,
Proper citation: ActiGraph Activity Monitor Devices (RRID:SCR_008399) Copy
THIS RESOURCE IS NO LONGER AVAILABLE,documented on February 1st, 2022. Instrument supplier providing eye tracking capabilities for behavioral labs as well as for MRI, MEG, and EEG research environments.
Proper citation: SR Research EyeLink Eye Trackers (RRID:SCR_009602) Copy
fNIR Imager 1100 is a new generation portable functional near-infrared (fNIR) imaging research tool capable of monitoring brain?s hemodynamics and thereby the cognitive state of the subject in natural environments. Neuroimaging Solution for Natural Environments: * fNIR is the only stand-alone and field-deployable technology able to determine localized brain activity. * fNIR can be readily integrated with other physiological and neurobehavioral measures that assess human brain activity, including eye tracking, pupil reflex, respiration and electrodermal activity. fNIR can also complement other techniques. * Studies have shown a positive correlation between a participant's performance and fNIR responses as a function of task load. * It has also been shown that fNIR can effectively monitor attention and working memory in real-life situations.
Proper citation: fNIR Devices (RRID:SCR_009623) Copy
http://www.scienceexchange.com/facilities/tubingen-ageing-and-tumour-immunology-group-tati
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. TATI is located at the Center for Medical Research (Zentrum fuer Medizinische Forschung, ZMF) within the University of Tuebingen Clinical School (Universitaetsklinikum Tuebingen) . We are engaged in immune monitoring (cancer immunotherapy, vaccination of elderly, Alzheimer) using 14-colour flow cytometry.
Proper citation: Tubingen Ageing and Tumour Immunology Group (RRID:SCR_012627) Copy
http://metap.helmholtz-muenchen.de/metap2/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 5,2023. Software tool for processing in metabolomics experiments., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: MetaP (RRID:SCR_014686) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_AssayDevelopment.aspx
Core facility that performs design, development, validation and pilot screening of biological high-throughput assays. It provides services such as designing and developing de-novo assays, converting low-throughput lab protocols (e.g. cuvette- or gel-based) into plate-based HTS assays, and access to major robotic equipment and resources. The facility also provides direct assistance with preparing screening-related grants, guidance through assay development stages, help in designing testing funnels, and generation of preliminary data.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Assay Development Core Facility (RRID:SCR_014867) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_Proteomics.aspx
Facility that provides mass spectrometry-based proteomics services with methods tailored to the needs of scientific investigators for routine mass spectrometric analysis of peptides and proteins, identification of novel proteins, characterization of post-translational modifications, and quantitative proteomics analysis of simple to complex biological samples. The facility identifies, validates and develops new methods designed for the characterization and identification of biologically important proteins. It also supports users with software applications and development, data analysis and experimental design of proteomics studies.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Proteomics Facility (RRID:SCR_014865) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_GenomicsDNAAnalysis.aspx
Core facility that provides sequencing services, access to equipment and consultation on experimental design and data analysis. Available instruments include the Life Technologies Ion Torrent PGM and Ion Proton sequencers. Core also provides amplification-free analysis of RNA expression using the NanoString nCounter, and additionally provides sequencing and analysis services to investigators outside of SBP. Included in the cost of sequencing is basic bioinformatic analysis (SNP/InDel calling, transcript abundance). Lastly, the core also provides advice on experimental design, and guidance on the capabilities of next-generation sequencing.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Genomics DNA Analysis Facility (RRID:SCR_014866) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_HighContentScreening.aspx
Core facility that provides access to the HTS plate and liquid handling infrastructure of the screening center, as well as the screening center�s cell culture facility. Other services include assay development, screening, and data analysis/mining expertise and services for high content screens. Consultation from the team is available for high content image-based screens including sample preparation, image acquisition, image analysis, image data management, and algorithm development.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute High-content Screening Core Facility (RRID:SCR_014869) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_CellularImaging.aspx
Medical research facility that supports research programs by providing access to sophisticated microscopes for digital imaging, as well as training, assistance and guidance. The core facility offers expertise, training and assistance in advanced biological microscopic imaging techniques and use of complex image processing software, use of well-maintained, aligned, and calibrated microscopic equipment, and troubleshooting of equipment and experimental problems.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cellular Imaging Facillity (RRID:SCR_014855) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_GenomicsMicroarrayQPCR.aspx
Facility that provides full-service microarray-based global analysis of gene expression in RNA samples from humans or mice using an Illumina platform. Services include RNA sample quality and quantity analysis, microarray analysis, and Q-PCR service and analysis, as well as special services such as RNA purification and Copy Number Variation analysis.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Genomics Microarray/Q-PCR Facility (RRID:SCR_014863) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_ViralVectors.aspx
Facility that provides cost-effective production of high-quality, high-titer lentiviral, retroviral and adenoviral vectors. Services include production of ready-to-transduce lentiviral and adenoviral particles, custom lentiviral, retroviral, and adenoviral production and titrations. Other activities of the facility include packaging, concentrating, and titration of user-supplied lentiviral constructs. Specialized services include custom lentiviral vector construction for constitutive or inducible cDNA/shRNA expression as well as promoter/enhancer reporter, viral packaging, and titration (ready-to-transduce control particles provided).
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Viral Vector Core Facility (RRID:SCR_014864) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_NMR.aspx
Facility that acts as a centralized shared resource for NMR studies on proteins, peptides, small molecules, and carbohydrates in solution or in solid state. It provides instrumentation and expertise for NMR data collection. It also provides consultation with investigators on the feasibility of NMR for structural studies of protein candidates, as well as the optimal method to obtain solution structures and binding information by multi-dimensional NMR techniques. It can also train users in basic spectrometer operations, trouble-shoot for instrumental and operational problems, and set up NMR experiments for users as requested.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute NMR Facility (RRID:SCR_014861) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_ProteinAnalysis.aspx
Facility that provides a variety of analytical services focused on biophysical characterization of structural and functional properties of proteins in solution, under native, non-denaturing conditions. Examples of services include quality control of protein samples (folding, stability, aggregation); measuring molecular weight of proteins, protein complexes, oligomers and assemblies; charcaterizing protein conformation and shape in solution; determining oligomeric state of protein (including stoichiometry and Kd for self-association) and measuring protein binding to proteins, peptides, small molecules, compounds, metals, nucleotides and other ligands (including determination of equilibrium (Kd) and kinetic rate (kon, koff) constants, stoichiometry, binding enthalpy and entropy).
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Protein Analysis Core (RRID:SCR_014862) Copy
https://www.spscientific.com/AboutOurTrustedBrands/
Commercial organization located in Warminster, Pennsylvania, USA, part of SP Industries, Inc. Provides VirTis, FTS Systems, Hotpack, Hull, Genevac, and PennTech scientific equipment. Manufactures freeze drying/lyophilization, centrifugal evaporation and concentration, temperature control/thermal management, glassware washers, controlled environments, vial washing and tray loading machines., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: SP Scientific (RRID:SCR_017367) Copy
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