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http://harvard.eagle-i.net/i/0000012a-2517-5e6f-5617-794280000000

Core facility that provides the following services: X-ray crystallography service, X-ray crystallography reference database access service, X-ray crystallographic data analysis and processing service, Access to x-ray crystallography using synchrotron radiation, X-ray crystallography advising and consultation service.

The X-ray Crystallography Facility located at 99 Brookline Ave. (Research North) was recently established as a core to serve the needs of investigators in the BIDMC and Harvard Medical School community interested in using structural biology as a tool in their research.

Proper citation: BIDMC X-ray Crystallography Core (RRID:SCR_009678) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012a-2518-e64e-5617-794280000000

Core facility that provides the following services: Real-Time PCR service, Real-time PCR training service.

Performs Real-Time-PCR and provides quantitative data on levels of gene expression. The Core comprises an ABI 7700 Sequence Detector System, equipped with all an investigator needs for experimental design/run and data processing.

Proper citation: BIDMC Real-Time PCR Core (RRID:SCR_009676) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012a-2517-32d8-5617-794280000000

Core facility that provides the following services: DNA injection service, Embryonic stem cell injection service, Transgenic mouse line rescue service, Transgenic mouse embryo handling services, Mouse assisted reproductive services.

The Beth Israel Deaconess Transgenic Core Facility opened in October of 1991.The Transgenic Core is a state-of-art facility that produces genetically altered animals.

Proper citation: BIDMC Transgenic Core Facility (RRID:SCR_009677) Copy   

•   Source: SciCrunch Registry
  

https://research.bidmc.org/radiology-research/MRI-Preclinical-Core

Preclinical MRI Core at Beth Israel Deaconess Medical Center provides services including imaging of anatomy and function for small animals including mice, rats, and amphibians. Ex vivo samples from larger animals and patients can be imaged. Offers consultation on protocol design and pilot data for new projects. Analysis services are available as well.

Proper citation: Beth Israel Deaconess Medical Center Preclinical MRI Core Facility (RRID:SCR_009674) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012b-00c4-d136-db6e-7a3f80000000

Core facility that provides the following services: In Vivo Magnetic Resonance Imaging (MRI), Quantitative Image Analysis: Standard Uptake Value (SUV), 3D Volume Measurements, Animal Handling Techniques: Blood Collection, Injections (IV, IP), Oral Gavage, Tumor Inoculation, Transcardiac Perfusion, etc., Whole-body and Tissue Cryosectioning, Ex Vivo Tissue Radioactivity Measurement.

Our goal is to provide state-of-the-art small animal imaging services to researchers in the Longwood Medical Area of Harvard Medical School. These services include multi-modality imaging, advanced data analysis, image fusion resources, and a satellite animal facility for longitudinal studies. A detailed description of our instruments and services are provided on our website, and we welcome questions and comments.

Proper citation: BIDMC Longwood Small Animal Imaging Core Facility (RRID:SCR_009670) Copy   

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https://research.bidmc.org/em-core

Core provides service for grossing, tissue processing, tissue embedding, thick and thin sectioning, staining grids, and taking images of samples in the electron microscope. Training is available to use the electron microscope independently. For tissue processing, we also have training or service for high pressure freezing, freeze substitution, and tissue embedding. The core also has the expertise to do Advanced 3-D Focused Ion Beam/Scanning Electron Microscopy and 3-D segmentation and analysis on cells or tissues.

Proper citation: Beth Israel Deaconess Medical Center Electron Microscopy Core Facility (RRID:SCR_009667) Copy   

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http://harvard.eagle-i.net/i/0000012a-2518-fb6c-5617-794280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27, 2023. Core provides services: RT PCR service, Gene expression profiling service, Proteomics analysis service, Bioinformatics and Systems Biology analyses, Next Generation Sequencing Service, Affymetrix Human and Mouse Gene 2.0 ST Arrays and 2.1 ST Arrayplates. Core proteomics facility for the Dana-Farber/Harvard Cancer Center. Workflows and algorithms for analysis of next-generation sequencing data including RNA-Seq, ChIP-Seq, Epigenetics-Seq and DNA seq, Comprehensive workflow for analysis of Microbiome sequencing data, Integrated systems biology analysis of transcriptome, miRNA, epigenome, metabolomics and proteomics data. Pipelines: MALDI Tissue imaging and targeted quantitative proteomics.

Proper citation: Beth Israel Deaconess Medical Center Genomics Proteomics Bioinformatics and Systems Biology Center (RRID:SCR_009668) Copy   

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http://harvard.eagle-i.net/i/0000012e-6cd0-f03d-55da-381e80000000

Core facility that provides the following services: Cell sorting service.

The Department of Pathology Flow Cytometry Facility provides flow cytometric analysis and cell sorting services to investigators in the Harvard Medical School and in the Harvard affiliated hospitals and institutions. The facility currently has a FACSCalibur for assisted as well as unassisted flow cytometric acquisition and analysis, and a FACSAria for cell sorting (performed by an expert technician).

Proper citation: HMS Flow Cytometry Facility (RRID:SCR_009666) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012a-2517-523f-5617-794280000000

Partially funded through Harvard Catalyst, the Clinical Research Coordinator Core is available to support and collaborate with investigators and their research teams in all phases of clinical research, providing services that include assisting with the organization, implementation and completion of clinical research studies.

Proper citation: BIDMC Clinical Research Coordinator Core Laboratory (RRID:SCR_009663) Copy   

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http://harvard.eagle-i.net/i/00000143-6d42-d9ec-0803-96bd80000000

Core facility that provides the following services: Fluorescence activated cell sorting, Data analysis and interpretation.

Cytometry and cell sorting core at the Center for Virology and Vaccine Research. The facility has a BD FACSAria II housed in a sterile biosafety cabinet in a BSL2+ facility, allowing sorting of unfixed, live cells into a variety of tubes and plates. Equipment, consultation, dedicated operator, and data analysis available to outside researchers. To schedule an appointment, please fill out and submit the Investigator Sort Form available on our website or contact us below.

Proper citation: BIDMC CVVR Flow Cytometry Core (RRID:SCR_009661) Copy   

•   Source: SciCrunch Registry
  

http://eagle-i.ea.vanderbilt.edu/i/00000139-a24f-c60a-b4bd-8a1180000000

This core facility can assist with measurements of reactive oxygen species, nitric oxide, and assist in measurements of vascular reactivity for investigators in the Vanderbilt community. The FRIMCORE employs state of the art methods, including electron spin resonance, fluorescent techniques and HPLC (High-Performance Liquid Chromatography) for measurement of reactive oxygen species and nitric oxide in cells and tissues.

Proper citation: Vanderbilt Free Radicals in Medicine Core (RRID:SCR_009541) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012a-251a-2c19-5617-794280000000

The mission of the Biomedical Research Informatics Core (BRIC) is to utilize the expertise of BIDMC ''informaticians'' with backgrounds in medicine, biology, engineering, biostatistics, and computer science to facilitate research at our institution by (a) providing a high level of service and experience in informatics that is difficult for individual laboratories to achieve and maintain, (b) developing the infrastructure required to address common informatics needs of all researchers, and (c) identifying areas in which there can be closer collaboration among life scientists and quantitative scientists. View our portfolio for examples of BRIC projects. To arrange for a free consultation, please contact Griffin Weber. If you choose to use BRIC services, hourly fees vary depending on the types of services needed. You will be given an estimate of the number of hours before any work begins.

Proper citation: BIDMC Biomedical Research Informatics Core Laboratory (RRID:SCR_009660) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012e-5946-2efe-55da-381e80000000

The Biostatistics Center provides support to MGH investigators, as well as serving as a Coordinating Center for several NIH-supported projects. The Center''s staff includes biostatisticians, physicians, research nurses, data managers, project managers, research assistants, and computing staff.

Proper citation: MGH Biostatistics Center (RRID:SCR_009913) Copy   

•   Source: SciCrunch Registry
  

http://xula.eagle-i.net/i/00000135-1fe5-4458-77e4-a45080000000

Core facility that provides the following services: Automated DNA sequencing, Quantitative real-time PCR, Genotyping service, Liquid handling service. The Genomics Core Facility is a core resource of LSU Health Science Center, sponsored jointly by the Cancer Center and Genetics Center. The Facility is committed to providing quality service by fulfilling the needs of the research community in a consistently rapid, dependable, and economical fashion. Services include automated DNA sequencing, using state-of-the-art instrumentation (ABI PRISM 3130XL Genetic Analyzers) and the latest protocols to ensure high quality results at reseasonable prices. The Facility also houses an ABI Prism 7900 HT (a high through-put real-time PCR system) and a Biomek2000 liquid handling robot.

Proper citation: LCRC Genomics Core Facility (RRID:SCR_009906) Copy   

•   Source: SciCrunch Registry
  

http://xula.eagle-i.net/i/00000135-6375-0806-77e4-a45080000000

Core facility that provides the following services: Probe hybridization, Microarray data analysis. In December 2000, the LSUHSC Program in Gene Therapy in conjunction with the Louisiana Gene Therapy Research Consortium created the Microarray Core to cater to the growing needs of investigators who wanted to perform expression studies. Since that time, our core has helped researchers from around the world process over 3000 samples, resulting in numerous peer-reviewed scientific publications.

Proper citation: LCRC Microarray Core (RRID:SCR_009907) Copy   

•   Source: SciCrunch Registry
  

http://jsu.eagle-i.net/i/0000012c-1c64-7caa-a830-7bcf80000000

The JHS is the largest single-site longitudinal, population-based, cohort study of 5,302 persons initiated in the fall of 2000 to prospectively investigate the determinants of CVD among African Americans in the Jackson, MS metropolitan statistical area. The JHS investigates the various genotype and phenotype factors that affect high blood pressure, heart disease, strokes, diabetes and other important diseases in African Americans. The primary objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans to learn how to best prevent this group of diseases in the future. More specific objectives include: 1. Identification of factors, which influence the development, and worsening of CVD in African Americans, with an emphasis on manifestations related to high blood pressure (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke and disorders affecting the blood vessels of the kidney). 2. Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies. 3. Attracting minority students to and preparing them for careers in health sciences.

Proper citation: Jackson Heart Study (RRID:SCR_009902) Copy   

•   Source: SciCrunch Registry
  

http://xula.eagle-i.net/i/00000135-8260-0cac-a9f8-d64580000000

Core facility that provides the following services: Colony Forming Unit (CFU) Assay, Differentiation assays. Core purpose: To propagate, expand and supply high quality samples of normal mesenchymal stem cells (MSCs) from in vitro cultures with appropriate quality control assurances for use by LCRC investigators who are studying any aspect of MSCs in relationship to cancer.

Proper citation: LCRC Adult Stem Cell Core (RRID:SCR_009903) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012e-4ec0-f696-550e-f59280000000

Core facility that provides the following services: DNA Synthesis Service.

The DNA Synthesis Lab serves the research community with custom oligonucleotides. The lab is capable of high-throughput standard, degenerate and modified oligo synthesis.

Proper citation: MGH CCIB DNA Synthesis Core (RRID:SCR_009900) Copy   

•   Source: SciCrunch Registry
  

http://harvard.eagle-i.net/i/0000012c-bca3-4116-02c0-2b6880000000

The West Quad Computing Group (WQCG) serves the research community of the BCMP and Cell Biology departments at Harvard Medical School. We provide support for your advanced computing needs, including design and maintenance of computational clusters, large data-set management, web and database backed applications, and workstation support, including workstations connected to research equipment. Please see Resources for more information, including a sample of some of our recent projects. We work in collaboration with the HMS Information Technology department. Please contact us using our support form for all of your computer support needs.

Proper citation: HMS West Quad Computing Group (RRID:SCR_009814) Copy   

•   Source: SciCrunch Registry
  

http://msm.eagle-i.net/i/0000012b-00c2-775d-353c-df7f80000000

Core facility that provides the following services: Basic animal care service, Clinical and health monitoring service, Humane euthanasia service, Animal disposal service, Animal quarantine service, Necropsy and diagnostics service, Animal vaccination service, Animal use consultation service, Breeding service, Animal sample collection service, Assistance with minor surgery, Animal tattooing service.

Access to CLAR facilities is restricted to authorized investigators with CLAR and IACUC approval. No individuals may enter the facilities without this CLAR/IACUC authorization. Since its inception, the Center for Laboratory Animal Resources (CLAR) has centralized most research and teaching animal care for the Atlanta University Center consortium. Our purpose is to provide total animal care services as needed to all academic and/or research faculty and staff affiliated with any one of the member institutions of the Atlanta University Center (AUC).

Proper citation: MSM Center of Laboratory Animal Resources (RRID:SCR_009935) Copy   

•   Source: SciCrunch Registry